Clinical trials: Osteo Arthritis Knee
Osteo Arthritis Knee, Pain, Chronic
Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis
Osteoarthritis (OA) affects aged above 45 years. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities.
- Trial name
- NCT03886142
- Testing
- radiofrequency, platelet rich plasma injection
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Osteo Arthritis Knee
Geniculate Artery Embolization for Knee Osteoarthritis
A prospective cohort study to study the effectiveness and safety profile of geniculate artery embolization for the treatment of symptomatic knee osteoarthritis.
- Trial name
- GAEKO (NCT03835988)
- Testing
- Geniculate Artery Embolization
- Where
- Canada
- Sponsor
- University of Calgary
Osteoarthritis, Knee, Osteo Arthritis Knee
Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed
Efficacy and safety study of resiniferatoxin versus placebo to manage pain in patients with knee osteoarthritis whose TKR surgery is delayed
- Conditions
- Osteoarthritis, Knee, Osteo Arthritis Knee, Knee Pain Chronic
- Trial name
- NCT04386980
- Testing
- Resiniferatoxin
- Sponsor
- Sorrento Therapeutics, Inc.
Knee Osteoarthritis
Follow-up of Osteo-articular Biomarkers After Spa Therapy in a Population With Knee Osteoarthritis and Their Correlation With the Clinical Evolution
Spa therapy is used in the treatment of various diseases and mainly osteoarthritis. Knee osteoarthritis is a very common rheumatic disease whose prevalence increases with longer life span and is a public health problem.
- Trial name
- BIOMARTHROSE (NCT04308369)
- Testing
- Blood collection arm
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CHI MONT DE MARSAN ET PAYS DES SOURCES
Osteo Arthritis Knee, Worries; Pain or Disability
The Role of Rumination and Worry in Pain and Functional Limitation in Knee Osteoarthritis
Knee osteoarthritis is a common degenerative joint disease in which pain severity often does not fully correspond with radiographic disease severity.
- Conditions
- Osteo Arthritis Knee, Worries; Pain or Disability, Rumination
- Trial name
- NCT07609056
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Osteo Arthritis Knee, Injection Site Discomfort
Vapocoolant Spray Application During Intraarticular Knee Injection
The goal of this observational study is to learn about the effects of vapocoolant spray applied during intraarticular knee injections on pain and anxiety compared to injections without any agent application in patients with knee…
- Conditions
- Osteo Arthritis Knee, Injection Site Discomfort, Injection Fear
- Trial name
- NCT05581433
- Testing
- Topical Cooling Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Istanbul Rumeli University
Osteo Arthritis Knee
Ultrasound Effect With Hyaluronate Injection on Risk of Fall in Geriatric Women With Knee Osteoarthritis
For many years' physiotherapists have been using ultrasound in treatment of knee osteoarthritis especially in geriatrics (people aged above 65 years) for its known therapeutic effect in relieving pain and improving knee function.
- Trial name
- NCT06078449
- Testing
- Therapeutic Ultrasonic, Hyaluronan intra-articular injection
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Badr University
Osteoarthritic Knee Pain, Osteo Arthritis of the Knee
Effects of High-Intensity Laser Therapy Combined With Exercise in Patients With Knee Osteoarthritis
The goal of this clinical trial was to determine whether high-intensity laser therapy (HILT) combined with exercise improves pain, physical function, and muscle strength in people with knee osteoarthritis.
- Conditions
- Osteoarthritic Knee Pain, Osteo Arthritis of the Knee, Osteoarthitis, Osteoarthritis (OA) of the Knee
- Trial name
- HILT-KOA (NCT07630259)
- Testing
- High Intensity Laser Therapy, Exercise
- Where
- Chile
- Volunteers
- 31 people
- Sponsor
- Universidad Metropolitana de Ciencias de la Educacion
Osteo Arthritis Knee
Effects of Compression Mobilization in OA Patients
The study Design was randomized control trial in which data was collected From Riphah Rehabilitation And Research Center and Pakistan Railway Hospital-IIMCT. Convenient sampling technique was used for data collection.
- Trial name
- NCT04944056
- Testing
- conventional physiotherapy, compression mobilization
- Where
- Pakistan
- Volunteers
- 39 people
- Sponsor
- Mir Arif Hussain
Osteoarthritis, Knee
Hip Joint Mobilizations and Strength Training in Patients With Knee OA Osteoarthritis
Knee osteoarthritis has been ranked 11th highest contributor to non-fatal burdens in the world. Many research studies have discussed the relationship of hip muscle with knee joint stating that impaired hip strength can be a…
- Trial name
- NCT04769531
- Testing
- Hip Joint Mobilizations, Hip joint Muscle strength training, knee strengthening and flexibility exercises
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Dow University of Health Sciences
Osteo Arthritis Knee
Black Seed Oil in Treatment of Osteoarthritis
Osteoarthritis is a continual illness of joints. We aim to investigate the effect of Nigella sativa oil in comparison with placebo on the reduction of osteoarthritis pain.
- Trial name
- NCT06029868
- Testing
- Black seed oil capsule
- Where
- Iran
- Volunteers
- 110 people
- Sponsor
- Ramsar international campus
Osteoarthritis, Knee, Osteoarthritis, Hip
Surgical Joint Registry MBJRF
The purpose of this study is to follow the patient's short term and long term clinical outcome after undergoing joint replacement surgery.
- Trial name
- MBJRFREG (NCT03484325)
- Where
- United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Memorial Bone and Joint Research Foundation
Osteo Arthritis Knee
Comprehensive Knee Osteoarthritis Index (CKOAI): Scale Development, Validation and Reliability Testing
Background: Symptoms, balance, mobility, activities of daily life (ADL) and quality of life (QoL) are to be considered in rehabilitation of the individuals with knee osteoarthritis (IKOA).
- Trial name
- CKOAI (NCT03498833)
- Testing
- Test-retest reliability testing
- Where
- India
- Volunteers
- 52 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Osteo Arthritis Knee, Balance
The Effect of Exercise Training on Balance and Functional Status in Individuals With Osteoarthritis'
The aim of this study was to evaluate and compare the effects of Clinical Pilates Exercise Training and Combined Exercise Training on balance and functional status in individuals with knee Osteoarthritis (OA).
- Trial name
- NCT04183933
- Testing
- Pilates Exercise, Combined Exercise
- Where
- Cyprus
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Osteo Arthritis Knee
Traditional Versus Alternative Alignment in TKR
As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients…
- Trial name
- NCT03196011
- Testing
- TKR with mechanical alignment method, TKR with alternative alignment method
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Osteo Arthritis Knee, Chronic Post-operative Pain
Pain Phenotyping in Knee OA: a Pilot Trial
Osteoarthritis (OA) is disease in which the joint breaks down, causing pain. The decision to surgically replace the knee, a procedure called total knee arthroplasty (TKA), depends on x-ray results as well as pain and dysfunction.
- Trial name
- NCT06066684
- Testing
- n/a, observational
- Where
- 2 sites in Canada
- Volunteers
- 55 people
- Sponsor
- University Health Network, Toronto
Obesity, Overweight
A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee
The main purpose of this study is to evaluate the safety and efficacy of retatrutide once-weekly in participants who have obesity or are overweight and have osteoarthritis (OA) of the knee. The study will lasts about 77 weeks.
- Conditions
- Obesity, Overweight, Osteo Arthritis Knee
- Trial name
- TRIUMPH-4 (NCT05931367)
- Testing
- Retatrutide
- Where
- 49 sites in United States, Australia and 4 more
- Volunteers
- 445 people
- Sponsor
- Eli Lilly and Company
Osteo Arthritis Knee
pAF for the Treatment of Osteoarthritis
This is a Phase I/II Randomized Double-Blinded Standard of Care (Corticosteroid) vs. Sterile Amniotic Fluid for Osteoarthritis
- Trial name
- NCT04886960
- Testing
- Amniotic Fluid Injection, Standard of Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Osteo Arthritis Knee, Pain, Postoperative
Extended Oral Tranexamic Acid After Total Knee Arthroplasty
The utilization of intraoperative tranexamic acid (TXA), whether administered intravenously or orally, has become a standard practice in total joint arthroplasty (TJA).
- Trial name
- NCT06618820
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Campbell Clinic
Osteo Arthritis of the Knee
Home-Based Leg Dexterity Trainer for Management of Knee Osteoarthritis
Rationale: Roughly 14 million adults aged 60 or older (10% male/13% female) in the United States experience symptoms of knee osteoarthritis (OA).
- Trial name
- NCT07397806
- Testing
- Lex Dexterity Trainer, Wobble Board
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Steadman Philippon Research Institute