Clinical trials: Osteoarthritis, Hip
Osteoarthritis of the Hip
Comparison of MIS Anterior Versus MIS Anterolateral Approach
Aim of the present investigation is to analyse the amount of muscle trauma in relation to the surgical approach and to the individual postoperative functional recovery.
- Trial name
- NCT02458144
- Testing
- Total hip arthroplasty
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROFEMUR® Gladiator HA Coated Modular Femoral Stems
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) and resurfacing components marketed in the European Union (EU).
- Trial name
- NCT02314611
- Testing
- PROFEMUR® Gladiator HA Coated Modular Femoral Stem
- Where
- Belgium
- Volunteers
- 154 people
- Sponsor
- MicroPort Orthopedics Inc.
Osteoarthritis, Hip, Femur Head Necrosis
Prospective Clinical 5-year Follow-up of the LINK® SP-CL® Hip Prosthesis Stem
The objective of this PMCF is to collect clinical and radiographic outcome information on Total Hip Arthroplasty (THA) performed with LINK® SP-CL® Hip Prosthesis Stem under routine conditions.
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Femoral Neck Fractures
- Trial name
- NCT02288117
- Where
- 4 sites in Germany, Italy and 1 more
- Volunteers
- 240 people
- Sponsor
- Waldemar Link GmbH & Co. KG
Osteoarthritis
Use of Autologous Adipose-Derived Stromal Vascular Fraction To Treat Osteoarthritis of Hip, Knee, Ankle, and Thumb Joints
This study will examine the safety and efficacy of autologous adipose-derived stromal vascular fraction (SVF) cells for treatment of hip, knee and thumb osteoarthritis (OA); monitoring adverse events and measuring pain, function…
- Trial name
- NCT03166410
- Testing
- Cell injection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Texas Plastic Surgery
Hip Osteoarthritis
Usability and Effectiveness of ReHub in Patients After Total Hip Arthroplasty
This is a randomized, non-blinded, parallel assignment, clinical trial for the evaluation of usability and effectiveness of ReHub, a telerehabilitation system made up of a cloud platform and an exercise kit with smart sensors…
- Trial name
- REHIP (NCT04176315)
- Testing
- Conventional Home-based Rehabilitation Plan, ReHub Home-based Rehabilitation Plan
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Bio-Sensing Solutions S.L. (DyCare)
Osteoarthritis, Hip
Effect of Local Infiltration Anesthesia With Ropivacaine on Pain After Primary Total Hip Arthroplasty
Background: The Local infiltration analgesic (LIA) technique has been widely used to reduce opioid requirements and improve the patient's mobilization after total hip arthroplasty (THA).
- Trial name
- NCT02359136
- Testing
- local infiltration anesthesia using Ropivacaine and Epinephrine, local infiltration anesthesia using saline, Multimodal analgesic regimen
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- St. Olavs Hospital
Total Hip Arthroplasty (THA), Osteoarthritis
A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary Hip System
A Multi-Center Study in Patients Undergoing Total Hip Arthroplasty with the Smith+Nephew CATALYSTEM™ Primary Hip System. The purpose of the study is to assess safety and performance of the CATALYSTEM™ and to support product…
- Conditions
- Total Hip Arthroplasty (THA), Osteoarthritis, Degenerative Joint Disease, Inflammatory Arthritis
- Trial name
- CATALYSTEM (NCT06564636)
- Testing
- CATALYSTEM
- Where
- 10 sites in United States, Canada
- Volunteers
- 119 people
- Sponsor
- Smith & Nephew, Inc.
Patellofemoral Osteoarthritis
Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study
The purpose of this research is to develop and test the feasibility of an exercise intervention for persons with painful knee osteoarthritis involving the patella (kneecap).
- Trial name
- NCT02825238
- Testing
- Supervised exercise program
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
Knee Osteoarthritis
Foot and Hip Abductor Strengthening in Patients With Knee Osteoarthritis.
The study will be Randomized controlled trail, Subject diagnosed with knee osteoarthritis meeting predetermined inclusion and exclusion criteria will be divided into two groups.
- Trial name
- NCT06343909
- Testing
- Hip abductor strengthening exercise, Intrinsic foot muscle strengthening along with conventional exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Primary Hip Osteoarthritis, Secondary Hip Osteoarthritis Due to Idiopathic Femoral Head Necrosis, Childhood or Inflammatory Disease
Fitmore Versus CLS Stem in Total Hip Arthroplasty. Bilateral One-stage Operations
Main question: Will use of a stem design that allows anatomical reconstruction of the hip joint improve the outcome in terms of hip function and patient satisfaction without causing any adverse effects? Background: Total hip…
- Conditions
- Primary Hip Osteoarthritis, Secondary Hip Osteoarthritis Due to Idiopathic Femoral Head Necrosis, Childhood or Inflammatory Disease, Bilateral Hip Disease, Surgical Treatment
- Trial name
- NCT03112785
- Testing
- Total hip arthroplasty (Fitmore or CLS uncemented femoral stem made by Zimmer-Biomet, Warshaw, USA)
- Volunteers
- 44 people
- Sponsor
- Sahlgrenska University Hospital
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
A Clinical Investigation of the M2a- Taper™ Hip System
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a- Taper™ Hip System
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis
- Trial name
- NCT00698633
- Volunteers
- 43 people
- Sponsor
- Biomet Orthopedics, LLC
Coxarthrosis
Compaction Femur Preparation for Cementless Total Hip Arthroplasty (THA) Unilateral
This is a prospective, randomized study comparing two different bone preparation techniques for insertion of a hydroxylapatite (HA) coated titanium cementless femoral stem.
- Trial name
- NCT00318396
- Testing
- Bone preparation technique: compaction, Bone preparation technique: conventional technique
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis, Hip Arthropathy
Topical Tranexamic Acid (TXA) in Joint Arthroplasty
The objective of this study is to evaluate the efficacy of topical tranexamic acid (TXA) in decreasing blood loss following both shoulder arthroplasty and primary total hip arthroplasty.
- Conditions
- Osteoarthritis, Hip Arthropathy, Shoulder Arthropathy
- Trial name
- NCT01937559
- Testing
- Tranexamic acid (TXA), Normal saline
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- The Hawkins Foundation
Hip Osteoarthritis
Dosage of Metal Ions in the Blood of Different Metal-on-metal Prostheses, in Correlation With Physical Activity
Prospective study including 6 groups of 20 patients with a total hip prosthesis. Five different types of metal-on-metal prostheses are studied, and 1 group with ceramic-on-ceramic prostheses acts as control group.
- Trial name
- NCT00285974
- Testing
- metal-on-metal total hip prosthesis versus ceramic-on-ceramic total hip prosthesis
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Hospital, Ghent
Hip Osteoarthritis, Osteonecrosis of the Femoral Head
Comparison of the Efficacy of Pericapsular Nerve Group Block Alone Versus Pericapsular Nerve Group Block Combined With Superior Cluneal and Superior Gluteal Nerve Blocks in Patients Undergoing Hip Surgery
In the clinic, total hip arthroplasty is a frequently performed surgical procedure that often results in moderate to severe postoperative pain.
- Conditions
- Hip Osteoarthritis, Osteonecrosis of the Femoral Head, Avascular Necrosis of Femur Head, Dysplasia of Hip Joint
- Trial name
- NCT07255768
- Testing
- 15 ml Bupivacaine Hcl 0.25% injection, 20 mL bupivacaine 0.25% injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Type 2 Diabetes, Hip Osteoarthritis
DexCom Hospital Study-CGM Directed Insulin Delivery
This is a pilot investigator initiated/sponsored clinical trial to evaluate the feasibility of using real-time DexCom G6 continuous glucose monitor (CGM or glucose sensor) trend data and an insulin-dosing algorithm to control the…
- Conditions
- Type 2 Diabetes, Hip Osteoarthritis, Knee Osteoarthritis
- Trial name
- NCT05504785
- Testing
- DexCom G6 continuous glucose monitor
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Thomas Jefferson University
Knee Osteoarthritis, Hip Osteoarthritis
The STavanger osteoARThritis Study
The START study will implement osteoarthritis (OA) treatment recommendations to increase the use of recommended treatment modalities and reduce non-desired events (e.g.
- Trial name
- START (NCT02876120)
- Testing
- Implementation
- Volunteers
- 330 people
- Sponsor
- Diakonhjemmet Hospital
Coxarthrosis; Primary
Evaluation of Proprioception in Patients With Total Hip Replacement
Disturbances of balance and postural stability are frequent in patients with coxarthrosis due to the damage to the mechanoreceptors, characteristic of arthritic degeneration, and muscular hypotrophy of the affected limb.
- Trial name
- PROPRIO-ATA (NCT05763368)
- Testing
- Clinical tests and proprioception evaluation
- Where
- Italy
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis, Pain
Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as Monotherapy compared with placebo in participants with signs and symptoms of osteoarthritis of the hip or knee that are not…
- Trial name
- NCT02336698
- Testing
- Fulranumab 1 mg, Fulranumab 3 mg
- Where
- 32 sites in United States, Poland and 2 more
- Volunteers
- 18 people
- Sponsor
- Janssen Research & Development, LLC
Hip Osteoarthritis, Hip Disease
Treatment of Osteoarthritis of the Hip Joint With Intra-articular Injection of Microfractured Autologous Adipose Tissue Containing Mesenchymal Stromal Cells.
The aim of the study is to evaluate the safety and efficacy up to 12 months of MF-AT in the echo-guided infiltrative treatment of hip OA through clinical, subjective and objective evaluations.
- Trial name
- Lipo-Hip (NCT05465096)
- Testing
- Micro-fragmented adipose tissue injection
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
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