Clinical trials: Osteoarthritis; Primary
Osteoarthritis
A Migration and Bone Density Study Comparing 2 Types of Bone Cement in the OptiPac Bone Cement Mixing System
The goal of this scientific study is to determine whether there are differences in early migration and prosthesis-near bone density when a standard knee prosthesis is fixed with Refobacin Bone Cement R or with Refobacin Plus Bone…
- Trial name
- NCT00678236
- Testing
- Refobacin Bone Cement R, Refobacin Plus Bone Cement
- Where
- Denmark
- Volunteers
- 54 people
- Sponsor
- University of Aarhus
Osteoarthritis of the Knee
Clinical and Stereoradiological Comparison of the Results After Primary Cemented Total Knee Arthroplasty Inserted With or Without the Use of a Tourniquet
The purpose of this study is to investigate if the use of a tourniquet during insertion of a cemented primary total knee arthroplasty will influence clinical and radiological (measured with RSA X-ray technique) outcome.
- Trial name
- NCT01488175
- Testing
- tourniquet, no tourniquet
- Where
- Denmark
- Sponsor
- Hvidovre University Hospital
Patient Satisfaction, Hip Osteoarthritis
Dual Mobility Cup: Does it Improve Patient's Satisfaction After Total Hip Arthroplastry?
Although the success of total hip arthroplasty, many patients were dissatisfied postoperatively. Patient's reported outcome measures become of a great importance in assessment of the results after joint replacement.
- Trial name
- NCT04333316
- Testing
- large head, dual mobility cup
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tanta University
Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis
Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty
This long-term outcomes study is designed to collect safety and efficacy data on designated, commercially available, hip arthroplasty products.
- Conditions
- Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis, Femur Head Necrosis, Congenital Dislocations
- Trial name
- NCT02230826
- Where
- 13 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Corin
Osteoarthritis Of Knee
Trial to Assess the Structural Effect and Long-term Symptomatic Relief of Intra-articular Injections of Hyaluronic Acid in Primary Knee OA
The present study is designed to test the hypothesis that Intra-Articular Hyaluronic Acid (IAHA) is superior to placebo in slowing structural progression and on long term symptomatic effect in primary knee Osteoarthritis (OA)…
- Trial name
- ViscOA (NCT02280538)
- Testing
- Intra-Articular Hyaluronic Acid
- Where
- 2 sites in Portugal
- Volunteers
- 300 people
- Sponsor
- Universidade Nova de Lisboa
Gonarthrosis; Primary, Varus Gonarthrosis
Safety of Bilateral HTO: One-Stage vs.Two-Stage: A Randomized Controlled Study
In this study, bilateral simultaneous high tibial osteotomy (HTO) was compared with staged bilateral HTO in terms of complications.
- Trial name
- NCT04399304
- Testing
- simultaneous bilateral high tibial osteotomy, Staged bilateral high tibial osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Bezmialem Vakif University
Degenerative Arthritis, Rheumatoid Arthritis
Zimmer Trabecular Metal Total Ankle PMCF
The primary objective of this study is to obtain implant survivorship and clinical outcome data for commercially available Zimmer Trabecular Metal Total Ankle implants used in primary or revision total ankle arthroplasty.
- Conditions
- Degenerative Arthritis, Rheumatoid Arthritis, Post Traumatic Arthritis
- Trial name
- NCT02038140
- Testing
- Zimmer Trabecular Metal Total Ankle System
- Where
- 11 sites in United States, Canada and 4 more
- Volunteers
- 120 people
- Sponsor
- Zimmer Biomet
Total Knee Replacement, Primary Knee Replacement
Comparison of Pivotal Medial Polyethylene Versus Ultra-congruent in Total Knee Arthroplasty
The aim of this study is to compare the forgotten joint score for the medial pivot polyethylene and ultra-congruent polyethylene which are used in total prosthetic replacement of the knee
- Conditions
- Total Knee Replacement, Primary Knee Replacement, Gonarthrosis
- Trial name
- MEPCAT (NCT06676189)
- Testing
- total knee arthroplasty with medial pivot polyethylene, total knee arthroplasty with ultra-congruent polyethylene
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Knee Osteoarthritis
Self-managed vs Supervised Exercise for Knee OA
Knee osteoarthritis (OA) is a common painful condition associated with pain and disability. OA healthcare costs the Danish society 4.6 billion DKK more per year than the non-OA population and we lack evidence on how best to…
- Trial name
- SELFIT (NCT07210931)
- Testing
- Self-managed exercise in a fitness center, Supervised Exercise
- Volunteers
- 300 people
- Sponsor
- Marius Henriksen
Osteoarthritis
A Study to Evaluate the Performance of the DePuy Low Contact Stress (LCS®) Complete Anterior-Posterior Glide (APG) Mobile Bearing Knee
The primary objective of this investigation is to determine the survivorship of the LCS Complete AP Glide mobile bearing knee prosthesis at 5 years.
- Trial name
- NCT00733486
- Testing
- L.C.S. APG Knee Anterior Posterior Glide knee
- Where
- 3 sites in South Korea
- Volunteers
- 233 people
- Sponsor
- DePuy International
Knee Osteoarthritis (Knee OA), OA
Kinesiophobia and Its Impact on Pain and Function in Knee Osteoarthritis
Knee osteoarthritis (OA) is the most common chronic joint disorder, especially in older adults, and is a leading cause of pain, disability, and reduced quality of life.
- Conditions
- Knee Osteoarthritis (Knee OA), OA, Kinesiophobia
- Trial name
- KinesiOA (NCT07161895)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara Training and Research Hospital
Arthroplasty, Replacement, Hip
Tritanium® Primary Acetabular Shell Study
This study will be a prospective, non-randomized evaluation of the Tritanium® Acetabular Shell for primary total hip replacement (THR) with a cementless application in a consecutive series of patients who meet the eligibility…
- Trial name
- NCT01063751
- Testing
- Tritanium® Primary Acetabular Shell
- Where
- 7 sites in United States
- Volunteers
- 275 people
- Sponsor
- Stryker Orthopaedics
Rheumatoid Arthritis, Osteoarthritis
Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement
The purpose of this study is to monitor the performance of a large metal-on-metal bearing from the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery or a total hip…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872547
- Testing
- DePuy ASR™ Hip System, DePuy ASR™ XL Head / ASR™ Acetabular Cup System
- Where
- 8 sites in Austria, Czechia and 6 more
- Volunteers
- 329 people
- Sponsor
- DePuy International
Localized, Primary Osteoarthritis, Post-traumatic Arthrosis of Other Joints, Shoulder Region
Aequalis Resurfacing Head Study
Aequalis® Resurfacing Head implant is a range of shoulder arthroplasty device available for the treatment of various shoulder pathologies. It received CE Mark in June 2007.
- Conditions
- Localized, Primary Osteoarthritis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Avascular Necrosis of the Head of Humerus
- Trial name
- NCT02444299
- Testing
- Shoulder hemi-arthroplasty
- Volunteers
- 100 people
- Sponsor
- Stryker Trauma and Extremities
Knee Osteoarthritis
Effect of Mechanical Traction and Therapeutic Exercises in Treatment of Primary Knee Osteoarthritis
The purpose of this study is to compare between therapeutic exercises and therapeutic exercises preceded by mechanical traction in treatment of patients with primary knee osteoarthritis attributed to the outcomes of pain, muscle…
- Trial name
- NCT04830748
- Testing
- Mechanical knee traction, Therapeutic exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hip Osteoarthritis, Knee Osteoarthritis
Determining the Impact of a Physiotherapist-Led Primary Care Model for Hip and Knee Pain - A Pilot Trial
This is a pilot cluster randomized controlled trial to to evaluate the individual and health system impacts of implementing a new physiotherapist-led primary care model for hip and knee pain in Canada.
- Trial name
- NCT05736133
- Testing
- Physiotherapist-led primary care model for hip and knee pain, Usual physician-led primary care model for hip and knee pain
- Where
- Canada
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Jordan Miller, PT, PhD
Osteoarthrosis
Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients
The study evaluates the pathophysiological effects of a single dose Methylprednisolone administered prior to total hip-arthroplasty (THA) surgery.
- Trial name
- NCT02445898
- Testing
- Methylprednisolone, Isotonic Sodium Chloride
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis, Intraoperative Bleeding
Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty
Hypotheses: Primary - A weighted dose of 20 mg/kg of tranexamic acid will be more efficacious than a single uniform dose of 1 gram in primary total knee arthroplasty (TKA) cases.
- Trial name
- NCT01651806
- Testing
- Tranexamic Acid standard dose, Females Tranexamic Acid weighted dose, Females receiving a uniform dose of TA
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Chronic Pain, Osteoarthritis
Acupuncture Approaches for Chronic Pain
Chronic pain is a major public health problem that places many burdens on individuals, including impairment of physical and psychological functioning, lost productivity, and side effects of medications used to treat pain.
- Conditions
- Chronic Pain, Osteoarthritis, Neck Pain, Back Pain
- Trial name
- AADDOPT-2 (NCT02456727)
- Testing
- Group/Community Acupuncture, Individual Acupuncture
- Where
- United States
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Total Hip Arthroplasty, Osteoarthritis, Hip
Migration in Total Hip Arthroplasty with a Cemented BiMobile Cup: Better Stability with More Cement?
Objective: The main objective of this study is to compare the (early) migration of the cemented BiMobile cup at two year post-surgery between two different cup sizes after standard optimal reaming, and consequently adjusting the…
- Trial name
- Be-Mobile (NCT04049279)
- Testing
- BiMobile standard cement, BiMobile larger cement, Avantage standard cement
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- JointResearch