Clinical trials: Osteoarthritis
Arthritis, Degenerative, Arthritis, Rheumatoid
Excia T Cementless EBRA Study
In this Post Market Clinical Follow-up Study (PMCF Study), the short-term clinical and radiological results of the cementless Excia T® prosthesis in routine clinical use shall be assessed and the migration taking place in the…
- Conditions
- Arthritis, Degenerative, Arthritis, Rheumatoid, Hip Fractures, Femur Head Necrosis
- Trial name
- NCT02799654
- Where
- Germany
- Sponsor
- Aesculap AG
Arthrosis, Traumatic Arthritis
The Medacta International AMIStem-P Post-Marketing Surveillance Study
This is a Post-Market Surveillance study of AMIStem-P femoral stem prosthesis
- Conditions
- Arthrosis, Traumatic Arthritis, Rheumatoid Polyarthritis, Congenital Hip Dysplasia
- Trial name
- NCT04997005
- Testing
- AMIStem-P
- Where
- 5 sites in France
- Volunteers
- 550 people
- Sponsor
- Medacta International SA
Osteoarthritis of the Knee
Efficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the Knee
The purpose of this study is to determine the efficacy of ADL5859 versus placebo and ADL5747 versus placebo in relieving pain in participants with osteoarthritis of the knee.
- Trial name
- NCT00979953
- Testing
- ADL5859, ADL5747, Oxycodone CR
- Where
- 11 sites in United States
- Volunteers
- 408 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Osteoarthritis, Knee
Long-term Safety and Performance of KiOmedine CM-Chitosan Supplementation in Advanced Symptomatic Knee Osteoarthritis
A single-blind randomized controlled design intended for the assessment of safety and performance of a single intra-articular injection of the IMD.
- Trial name
- PIONEER (NCT05214807)
- Testing
- KiOmedine® CM-Chitosan, Synvisc-One®
- Where
- Belgium
- Volunteers
- 104 people
- Sponsor
- Kiomed Pharma
Osteoarthritis
Gait and Functional Improvement in Total Knee Arthroplasty With the Use of Verasense for Soft Tissue Balancing
The primary objectives of this study are to understand the effects of soft-tissue balancing on Gait, function and rehabilitation potential after sensor-assisted Total Knee Arthroplasty and correlate Intra-operative subjective…
- Trial name
- NCT02290119
- Testing
- Sensor-assisted TKR (Verasense), Control - Without the use of Verasense
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Orthosensor, Inc.
Osteoarthritis
10003 PRO Current Products
This post-marketing investigation will evaluate the functional knee performance of Subjects who have undergone primary total knee arthroplasty (TKA).
- Trial name
- 10003 (NCT01497730)
- Testing
- Total Knee Replacement
- Where
- 22 sites in United States, Australia and 2 more
- Volunteers
- 842 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis, Knee
A Telehealth Study of a Wearable Electroceutical & Sports Sleeve for Knee Osteoarthritis Pain Relief & Improved Function
The purpose of this telemedicine 24-person open-label study is to evaluate the safety and usability of a proprietary wearable microcurrent electroceutical (a device that delivers micro-ampere electronic pulses) made by Healables…
- Trial name
- HEAL01WMCOA1 (NCT04938271)
- Testing
- HEAL-122 microcurrent electroceutical with e-textile sports knee sleeve
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Healables Ltd.
Osteoarthritis
Evaluation of a New Formulation Useful for the Osteoarthrosis Treatment
Abstract Kondrium, is a pharmaceutical composition for the treatment of osteoarthritis (OA). This study was designed to evaluate the efficacy and safety of kondrium in the treatment of OA of knee.
- Trial name
- EFO (NCT00977444)
- Testing
- kondrium, kondrium f, methyl prednisolone (corticosteroid)
- Where
- Mexico
- Volunteers
- 114 people
- Sponsor
- Nucitec
Osteoarthritis
A Randomized Control Trial to Assess Early Clinical and Functional Outcome of the ROCC and LCS Total Knee Implant Designs
This is a prospective Randomised Control Trial to compare the Early Clinical and Functional Outcome of the ROCC and LCS total knee arthroplasty implant designs.
- Trial name
- NCT00755144
- Testing
- LCS Knee, ROCC Knee
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Efficacy Study of Intra-articular Hyaluronic Acid in the Knee Osteoarthritis
The purpose of this study is to prove the non-inferiority of the intra-articular injection of hyaluronic acid (Sinovial®) in the symptomatic treatment of knee OA in comparison to Synvisc®.
- Trial name
- NCT00556608
- Testing
- Sinovial® (syringe containing sodium hyaluronate solution), Synvisc® ( syringe containing Hylan G-F 20 solution)
- Where
- 20 sites in Czechia, France and 4 more
- Volunteers
- 381 people
- Sponsor
- IBSA Institut Biochimique SA
Knee Osteoarthritis
Long-term Study of The Press Fit Condylar (P.F.C.) Sigma Total Knee Replacement System
The main purpose of this study is to record information from clinical and radiographic examinations and patient assessment questionnaires before surgery and at suitable postoperative intervals to assess the functioning and…
- Trial name
- NCT00734110
- Testing
- P.F.C. Sigma Total Knee System
- Where
- United Kingdom
- Volunteers
- 723 people
- Sponsor
- DePuy International
Pain
A Study of Topical XG004 in Participants With Osteoarthritis of the Knee
This is phase 1 placebo controlled study to evaluate the safety, tolerability and pharmacokinetics of XG004 applied topically in participants with osteoarthritis of the knee
- Trial name
- NCT05454020
- Testing
- XG004
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- Xgene Pharmaceutical Group
Osteoarthritis, Knee
Safety Study of TissueGene-C in Degenerative Joint Disease of the Knee
The study is being conducted to investigate the safety and activity of TissueGene-C injected into the knee joint of patients with chronic degenerative joint disease (DJD) who will be undergoing total knee replacement.
- Trial name
- TGC-03-01 (NCT00599248)
- Testing
- TissueGene-C
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Kolon TissueGene, Inc.
Pain, Osteoarthritis, Hip
Observational Study Investigating the Effectiveness of Fentanyl Matrix in Relieving Pain and Improving Function in Patients With Osteoarthritis of the Knee or Hip
The purpose of this study is to investigate the utility of fentanyl matrix for the treatment of pain due to osteoarthritis (OA) of knee or hip, which was not adequately controlled by non-opioid analgesic (e.g.
- Conditions
- Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT01119885
- Testing
- fentanyl matrix
- Volunteers
- 742 people
- Sponsor
- Janssen Korea, Ltd., Korea
Knee Osteoarthritis
Evaluation of NMES Therapy for Pain Relief Associated With Knee Osteoarthritis
A roll-over study of the current CM-2019 trial to assess the same preplanned outcomes of CM-2019 at 14 weeks.
- Trial name
- NCT04367597
- Testing
- Home-based Neuromuscular Electrical Stimulation (NMES) therapy
- Where
- 5 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CyMedica Orthopedics, Inc
Pain, Chronic Back Pain
An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)
The purpose of this study is to evaluate tapentadol Extended Release (ER) in the treatment of moderate to severe chronic pain in participants with a diagnosis of chronic low back pain (LBP) or osteoarthritis (OA) of the hip or…
- Conditions
- Pain, Chronic Back Pain, Chronic Low Back Pain, Osteoarthritis Pain In The Hip or Knee
- Trial name
- NCT01631513
- Testing
- Nucynta ER
- Where
- 7 sites in United States
- Sponsor
- Janssen Scientific Affairs, LLC
Osteoarthritis
Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.
The objective of this study is to assess the safety and efficacy of the buprenorphine transdermal system (5, 10, and 20 mg) in comparison to placebo transdermal system in subjects with osteoarthritis pain.
- Trial name
- NCT00314652
- Testing
- Buprenorphine transdermal delivery system
- Where
- 22 sites in United States
- Volunteers
- 260 people
- Sponsor
- Purdue Pharma LP
Chronic Pain
A Study Comparing the Effectiveness and Safety of Extended Release Tramadol Versus Placebo for the Treatment of Osteoarthritis (OA) of the Knee
The purpose of this study is to compare the analgesic effectiveness and safety of tramadol HCl ER to placebo in patients with moderate to severe pain due to osteoarthritis (OA).
- Trial name
- NCT00348010
- Testing
- Tramadol HCl ER
- Volunteers
- 245 people
- Sponsor
- Bausch Health Americas, Inc.
Hip Osteoarthritis
Evaluation of the Structure Modifying Effect of Avocado-Soybean Unsaponifiables in Hip Osteoarthritis
This study aims to assess the long term (three years) ability of ASU (Avocado Soya unsaponifiable) to slow the decrease of radiographic JSW (Joint Space Width) in hip osteoarthritis (OA).
- Trial name
- ERADIAS (NCT01062737)
- Testing
- ASU
- Where
- France
- Sponsor
- Laboratoires Expanscience S.A.
Low Back Pain, Migraine
Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain
The purpose of this study is to evaluate the safety and tolerability of OraVescent fentanyl for the potential treatment of breakthrough pain episodes in patients who have chronic noncancer pain.
- Conditions
- Low Back Pain, Migraine, Diabetic Neuropathies, Osteoarthritis
- Trial name
- NCT00228605
- Testing
- OraVescent Fentanyl
- Where
- 38 sites in United States
- Volunteers
- 500 people
- Sponsor
- Cephalon
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