Clinical trials: Osteoarthritis Arthritis
Primary Osteoarthritis
Effect of Zoledronic Acid in Primary Knee Osteoarthritis
We try to find out the effect of zoledronic acid over pain of primary knee osteoarthritis and also functional status in a period of 6 months.
- Trial name
- NCT06051344
- Testing
- Zoledronic acid
- Where
- Bangladesh
- Volunteers
- 92 people
- Sponsor
- Toufiqe-E-Ealahi
Glenohumeral Osteoarthritis, Proximal Humerus Fracture
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Shoulder Prosthesis System
This study is designed as a prospective, multicenter, observational post-market clinical follow-up (PMCF) study to evaluate the safety and effectiveness of the Tipmed™ Shoulder Prosthesis System at 12 months postoperatively.
- Conditions
- Glenohumeral Osteoarthritis, Proximal Humerus Fracture, Rotator Cuff Arthropathy, Rheumatoid Arthritis
- Trial name
- NCT07678034
- Testing
- Tipmed™ Reverse Shoulder Prosthesis System, Tipmed™ Shoulder Prosthesis System (Hemiarthroplasty Configuration)
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Osteoarthritis Knee Pain
A Study in the Treatment of Osteoarthritis Knee Pain
To gather data on whether a new drug for osteoarthritis knee pain will be safe and have an effect on pain levels.
- Trial name
- NCT00790790
- Testing
- LY545694 49 mg, LY545694 105 mg
- Where
- 10 sites in United States, Puerto Rico and 1 more
- Volunteers
- 147 people
- Sponsor
- Eli Lilly and Company
Pain, Stiffness
Telerehabilitation for Knee Osteoarthritis: Study Protocol
Patient Recruitment and Enrolment All patients diagnosed with knee OA who present at Artros Medical Center for an orthopaedic specialist consultation will undergo a radiological examination.
- Conditions
- Pain, Stiffness, Physical Function
- Trial name
- NCT07137897
- Testing
- Telerehabilitation, Control group
- Where
- Slovenia
- Volunteers
- 118 people
- Sponsor
- University of Novo Mesto
Knee Osteoarthritis
To Evaluate the Performance and Safety of the Medical Device IRADYN in Subjects With Osteoarthritis of the Knee
The benefits of single or repetitive administration (1 to 6) can have similar result in terms of muscular strength and patients' quality of life improvement, benefiting of the advantages of polymerized polynucleotides (IRADYN)…
- Trial name
- IRADYN (NCT05206474)
- Testing
- IRADYN
- Where
- 2 sites in Romania
- Volunteers
- 50 people
- Sponsor
- I.R.A. Istituto Ricerche Applicate S.p.A.
Metabolic Syndrome, Osteoarthritis, Hip
Effects of a Clinical Dietary Intervention During Inpatient Treatment
The purpose of the study is a scientific and prospective documentation of the clinical effects of an inpatient treatment at the Immanuel Hospital of Berlin, in the department for complementary and integrative medicine, with the…
- Conditions
- Metabolic Syndrome, Osteoarthritis, Hip, Osteoarthritis, Knee, Rheumatoid Arthritis
- Trial name
- FASTA (NCT03785197)
- Testing
- Prolonged modified fasting
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Charite University, Berlin, Germany
Osteoarthrosis
A Comparison of Two Total Hip Replacements: Hip Resurfacing System Versus Mallory-Head/Exeter
The purpose of this study is to compare two total hip replacement systems: Hip Resurfacing System (ReCap) versus Mallory-Head/Exeter.
- Trial name
- NCT00116948
- Testing
- ReCap, Hip resurfacing system, Biomet
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Osteoarthritis
Safety of Diclofenac Sodium Gel in Knee Osteoarthritis
This study will test the efficacy and safety of topical Voltaren in the treatment of knee osteoarthritis.
- Trial name
- NCT00171691
- Testing
- Diclofenac Topical Sodium Gel 1%
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Novartis
Medial Collateral Ligament Lesions, Knee Osteoarthritis
Comparison of the Efficacy of Ultrasound-Guided Injections of Saline, High-Concentration Dextrose, and Ligament Repair Agents for the Treatment of Medial Collateral Ligament Pathology in Degenerative Knee Osteoarthritis: A Randomized Double-Blind Trial.
The goal of this clinical trial is to evaluate the effectiveness of STABHA, high-concentration glucose water, and saline injections in treating knee osteoarthritis with medial collateral ligament lesions.
- Trial name
- NCT06620874
- Testing
- STABHA Injection, High-Concentration Glucose Water Injection, Saline Injection
- Volunteers
- 51 people
- Sponsor
- Chen Ting-an
Osteoarthritis, Knee, Pain
Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis
Osteoarthritis (OA) in the knee is characterized by chronic inflammatory pain that is not necessarily related to the amount of joint damage.
- Conditions
- Osteoarthritis, Knee, Pain, Physical Activity, Mitochondrial Pathology
- Trial name
- NCT03344913
- Testing
- Walking
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Knee Osteoarthritis
Characteristics of Patients Declining INKA Trial Participation
The objective of this study is to compare baseline characteristics of overweight knee OA patients accepting vs. declining enrolment in the INKA trial (NCT05172843) to explore if enrolled patients differ systematically from the…
- Trial name
- n-INKA (NCT05215678)
- Testing
- Acceptance of invitation to trial participation, Declining invitation to trial participation
- Where
- Denmark
- Volunteers
- 129 people
- Sponsor
- Marius Henriksen
Osteoarthritis
Pilot Testing a Patient and Provider Intervention for Managing Osteoarthritis in Hispanic Adults.
Hispanics are affected by arthritis at a slightly lower age-adjusted rate compared to non-Hispanic whites and African Americans.
- Trial name
- PRIMO-Latino (NCT01782417)
- Testing
- patient and provider intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Hip Osteoarthritis, Hip Arthroplasty
Collared Versus Collarless Femoral Implants for Total Hip Arthroplasty
This is a randomized control trial that will investigate whether a collared hip replacement implant provides greater stability compared to a collarless option.
- Trial name
- NCT03558217
- Testing
- Collared Femoral Implant, Collarless Femoral Implant
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis, Varus Malalignment
Ellipse Intramedullary High Tibial Osteotomy Nail Study
The purpose of this study is to collect outcomes data in patients implanted with the Ellipse IM HTO Nail System.
- Trial name
- NCT02519218
- Testing
- Ellipse Technologies Intramedullary High Tibial Osteotomy Nail System
- Volunteers
- 6 people
- Sponsor
- Ellipse Technologies, Inc.
Knee Replacement, Hip Replacement
Perioperative Hyperglycaemia in Primary Total Hip and Knee Replacement
The purpose of this study is to analyze how common stress hyperglycaemia (abnormally high blood glucose) is in primary hip and knee replacement surgeries and which factors predispose to hyperglycaemia.
- Conditions
- Knee Replacement, Hip Replacement, Hyperglycemia
- Trial name
- HyTe-1 (NCT01021826)
- Where
- Finland
- Volunteers
- 193 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Knee Osteoarthritis
Efficacy of Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis.
Knee osteoarthritis (OA) causes patients considerable joint pain and leads to instability, reduced range of motion, and functional limitations.
- Trial name
- NCT03379168
- Testing
- Microfragmented Adipose Tissue (Lipogems), Corticosteroid injection, Saline
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dustin L. Richter, MD
Osteoarthritis of Knee, Osteoarthritis Hip
Cannabinoids for Osteoarthritis Pain Effectiveness Trial
This study aims to investigate whether oral cannabis extracts can effectively manage pain caused by osteoarthritis (OA), a common joint condition affecting one in seven Canadians.
- Trial name
- COPE (NCT06878417)
- Testing
- CBD, THC
- Where
- 3 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Osteoarthritis
A Study to Investigate the Efficacy and Safety of GSK3196165 in Inflammatory Hand Osteoarthritis
This is a randomized, Phase IIa, multicentre, double-blind, placebo-controlled parallel group study with the primary objective to assess the efficacy potential of GSK3196165 on pain, in subjects with active inflammatory hand…
- Trial name
- NCT02683785
- Testing
- GSK3196165
- Where
- 16 sites in United States, Germany and 3 more
- Volunteers
- 44 people
- Sponsor
- GlaxoSmithKline
Osteoarthritis, Rheumatoid Arthritis
PS150 Total Knee Arthroplasty Outcomes Registry
This registry is intended to evaluate the clinical outcomes of the DePuy P.F.C. Sigma PS150 RP Total Knee System. 200 participants will be enrolled prospectively or retrospectively and the follow up period will be 5 years.
- Trial name
- NCT02319291
- Testing
- P.F.C. Sigma PS150 RP Total Knee System
- Where
- 4 sites in Australia, South Korea
- Volunteers
- 175 people
- Sponsor
- DePuy Orthopaedics
Knee Osteoarthritis
Assessment of Protective Effect of JOINS on Cartilage in Knee Osteoarthritis
A Pilot study Randomized and Double-blinded Placebo controlled In 2 parallel group (JOINS 200mg:Placebo = 1:1) Overall 24 months treatment (JOINS:Placebo comparison up to 12 months, Additional follow-up assessment up to 24…
- Trial name
- Joins_Carp_Ⅳ (NCT01293955)
- Testing
- JOINS 200mg
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- SK Chemicals Co., Ltd.
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