Clinical trials: Osteoarthritis Arthritis
Degenerative Joint Disease, Osteoarthritis
Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA)
You are being asked to take part in this research study because you are scheduled to have total hip replacement (arthroplasty) surgery.
- Trial name
- NCT01391182
- Testing
- EACA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Blood Loss, Pain
Role of Autologous Platelet Rich Plasma in Total Knee Arthroplasty
This study was designed to evaluate the efficacy of leucocyte free autologous platelet rich plasma on blood loss, pain, wound healing and functional outcome after total knee arthroplasty.
- Trial name
- PRPTKA2012 (NCT01563380)
- Testing
- Platelet rich plasma
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Osteoarthritis, Hip
Metal-metal Articulations Versus Standard 28 mm Cementless Total Hip Arthroplasty
Younger hip patients often need revision of their hip replacement due to wear and loosening. Newer concepts (resurfacing and large head total hip replacement) with articulation surfaces in metal may reduce the wear, increase the…
- Trial name
- NCT01113762
- Testing
- articular surface replacement ASR, DePuy, ReCap/Magnum modular head, Biomet, Bimetric stem, mallory/head cup, 28 mm ceramic head, Biomet
- Where
- 2 sites in Denmark
- Volunteers
- 71 people
- Sponsor
- University of Southern Denmark
Inflammatory Tissue Disorder, Osteoarthritis
Mobile - Bearing Knee Study
To evaluate the safety and efficacy of the Encore Mobile-Bearing Knee.
- Conditions
- Inflammatory Tissue Disorder, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
- Trial name
- NCT00765362
- Testing
- Encore Mobile-Bearing Knee
- Where
- 8 sites in United States
- Volunteers
- 419 people
- Sponsor
- Encore Medical, L.P.
Osteoarthritis
Resiliency in Total Joint Arthroplasty
The investigators primary objective is to determine how does participation in StreaMD affect patient reported outcomes after Total Hip Arthroplasty (THA) or Total Knee Arthroplasty (TKA)?
- Trial name
- NCT04357262
- Testing
- StreaMD
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Utah
Bone Diseases, Infectious, Musculoskeletal Diseases
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health.
- Conditions
- Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis
- Trial name
- MVMS_MRI (NCT04536103)
- Testing
- MRI
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Xiaojuan Li
Osteoarthritis, Thumb Arthritis
Predictive Model for 1-Year Pain and Function Outcomes After Thumb Joint Surgery in Osteoarthritic Patients
This study aims to develop a predictive model to help doctors better understand expected outcomes one year after thumb joint surgery for osteoarthritis.
- Conditions
- Osteoarthritis, Thumb Arthritis, Arthroplasty of the MCP Joint
- Trial name
- NCT06740851
- Testing
- Touch® Trapeziometacarpal Joint Arthroplasty
- Where
- Switzerland
- Volunteers
- 330 people
- Sponsor
- Michael Oyewale
Knee Osteoarthritis, Pain
The Effects of Collateral Meridian Therapy for Knee Osteoarthritis Pain Management
Collateral meridian therapy (CMT) is a recently developed technique according to traditional Chinese medicine (TCM) experiences, differing from traditional Chinese acupuncture in numerous manners.
- Trial name
- NCT01532531
- Testing
- "GEMORE" Multi-Function Electrotherapy Stimulator
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- Taichung Armed Forces General Hospital
Osteoarthritis, Peripheral
Innovative Device for Pain Management by Millimeter Band Radiation : Electronic-Pain Killer.
In this study, in addition of conventional treatment, the efficacy of the medical device, Remedee One, in medical care of patients with peripheral osteoarthritis pain is evaluated.
- Conditions
- Osteoarthritis, Peripheral, Pain
- Trial name
- Epikarthrose (NCT04590079)
- Testing
- Conventional pain treatment with daily sessions with innovative medical device, Remedee One, for pain management by Millimeter Band Radiation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Knee Osteoarthritis
Prospective Evaluation of Biomarkers Variability in Knee Prosthetic Surgery
Bone quality is an important factor influencing the outcome of total knee replacement (TKR) surgery. Therefore, assessing bone quality preoperatively could help the surgeon in the choice of the most appropriate prosthetic…
- Trial name
- NCT01971931
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Milan
Knee Osteoarthritis
Magnetic Field Therapy Versus Transcutaneous Electrical Nerve-stimulation in Knee Osteoarthritis
The effectiveness of PEMF in improving physical function among Osteoarthritic (OA) patients remains a topic of debate, leading to the American College of Rheumatology not yet endorsing its use in OA treatment.
- Trial name
- NCT06406231
- Testing
- comparing efficacy of TENS and PEMF in knee osteoarthritis
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Spine Degeneration, Hip Arthritis
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
This study aims to evaluate the effectiveness of a mobile application in improving postoperative rehabilitation outcomes among patients undergoing orthopedic surgery.
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Trial name
- NCT06407427
- Testing
- App for in-bed conditioning exercises, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Knee Osteoarthritis
Stability of Contemporary Knee Arthroplasty
Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship.
- Trial name
- NCT02861794
- Testing
- Medacta International, GMK Sphere medially stabilized knee
- Where
- Norway
- Volunteers
- 44 people
- Sponsor
- Oslo University Hospital
Muscle Atrophy
Safety and Tolerability of IMM01-STEM in Patients With Muscle Atrophy Related to Knee Osteoarthritis.
An open-label dose escalation study to assess the safety and tolerability of IMM01-STEM in participants with muscle atrophy related to knee osteoarthritis
- Trial name
- STEM-MYO (NCT05211986)
- Testing
- IMM01-STEM
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Immunis, Inc.
Osteoarthritis
Balneotherapy and Echocardiographic Findings in Osteoarthritis
This prospective observational study aims to evaluate changes in heart function using echocardiography before and after a standardized balneotherapy program in adult and elderly patients with osteoarthritis.
- Trial name
- NCT06923969
- Testing
- balneotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Bursa City Hospital
Osteoarthritis of the Knee
A Study to Evaluate Safety of Three Intra-articular Injections of Ampion in the Knee of Adults With Osteoarthritis Pain
Phase 1 will evaluate the safety of 3 intra-articular injections of Ampion™ administered 2 weeks apart to adults with osteoarthritis of the knee.
- Trial name
- NCT02184156
- Testing
- 4 mL injection of Ampion
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Osteoarthritis
Qigong Therapy for Individuals With Knee Osteoarthritis
The purpose of this study is to evaluate the effectiveness of Qigong therapy, an ancient Chinese practice, for pain relief and symptom improvement in people with knee osteoarthritis (OA).
- Trial name
- NCT00104156
- Testing
- External Qigong therapy
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Knee Osteoarthritis
Hydrotherapy Intervention in Elderly With Knee Osteoarthritis
Knee osteoarthritis is a common condition characterized by pain and functional disability in older people. Prevalence increases with age and is more frequent in older women.
- Trial name
- NCT02048956
- Testing
- Hydrotherapy intervention, Control group
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Universidad de Granada
Osteoarthritis, Pain
Celebrex Total Knee Arthroplasty Study
This study will investigate the benefits of administering celecoxib (Celebrex), a selective cyclooxygenase -2 (COX-2) inhibitor, in treating osteoarthritis (OA) subjects undergoing elective unilateral primary total knee…
- Trial name
- NCT00359151
- Testing
- Celecoxib
- Where
- 7 sites in United States
- Volunteers
- 22 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Idiopathic Osteoarthritis
Moxibustion for Knee Osteoarthritis
This study aims to assess the feasibility, effectiveness and safety of moxibustion for symptom management and function improvement in patients with knee osteoarthritis, compared to usual care group.
- Trial name
- NCT01354860
- Testing
- Moxibustion treatment plus usual care, Usual care alone group
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea Institute of Oriental Medicine
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