Clinical trials: Osteoarthritis Arthritis
Knee Osteoarthritis
Exercise and Pain Sensitivity in Knee Osteoarthritis
A commonly administered conservative non-pharmacological treatment for OA is exercise, with beneficial effects in terms of reduced pain and disability. While the link between exercise and reduced disability is mediated by e.g.
- Trial name
- NCT01545258
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Frederiksberg University Hospital
Primary Elective Hip Arthroplasty (THA), Primary Elective Total Knee Arthroplasty (TKA)
Digital Patient Journey Solution for Patients Undergoing Elective Hip and Knee Arthroplasty Dueto Primary Osteoarthritis
This is an interventional study which aims at assessing the effects of a digital patient journey solution in patients undergoing elective hip and knee arthroplasty due to primary osteoarthritis.
- Trial name
- NCT04083326
- Testing
- Digital Patient Journey Solution
- Where
- Finland
- Volunteers
- 69 people
- Sponsor
- VTT Technical Research Centre of Finland
Chronic Knee Pain, Chronic Knee Osteoarthritis
Treating Chronic Pain of Peripheral Nerve Origin With the Novel Noninvasive Hypersound Neuromodulation System
First, the subject will undergo screening and provide informed consent. Baseline measurements are then taken. The subject remains seated with back support throughout the session.
- Conditions
- Chronic Knee Pain, Chronic Knee Osteoarthritis, Post Surgical Neuropathic Pain
- Trial name
- NCT06626854
- Testing
- RF-PNS
- Volunteers
- 5 people
- Sponsor
- Hypersound Medical Inc
Osteoarthritis (Knee), Metabolic Syndrome (MetS)
Effect of Resistance Exercises on Serum IGF-1 Levels in Knee Osteoarthritis
The goal of this clinical trial is to evaluate the effects of a resistance exercise program on serum Insulin-like Growth Factor 1 (IGF-1) levels in patients with knee osteoarthritis.
- Trial name
- NCT07890155
- Testing
- Resistance Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Moderate to Severe Osteoarthritis
Phase 1, Dose Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SM04690 in Moderate to Severe Knee Osteoarthritis (OA)
The purpose of this study is to find the optimal dose of SM04690 that can be safely given by intra-articular injection into the target knee joint of subjects with moderate to severe osteoarthritis.
- Trial name
- NCT02095548
- Testing
- SM04690, 0.03mg/2mL, SM04690, 0.07mg/2mL, SM04690, 0.23mg/2mL
- Where
- 7 sites in United States
- Volunteers
- 61 people
- Sponsor
- Biosplice Therapeutics, Inc.
Observational Study, Geniculate Artery
Prospective Observational Study Of Geniculate Artery Embolization For Symptomatic Knee Osteoarthritis In A Cancer Population
To explore associations with demographics/clinical factors; assess trajectories via annual follow-up; evaluate healthcare utilization and barriers; oversample >10-year survivors.
- Conditions
- Observational Study, Geniculate Artery, Embolization, Symptomatic Knee Osteoarthritis
- Trial name
- NCT07807943
- Testing
- SOC (Standard of care)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Hip Osteoarthritis
Prospective Catalystem CT-RSA
Multi-Centre Study in patients undergoing Total Hip Arthroplasty with the Smith+Nephew CATALYSTEM™ Primary Hip System. The primary objective is to establish the mean inferior stem migration (subsidence) of the CATALYSTEM™ stem…
- Trial name
- NCT07698717
- Testing
- CATALYSTEM
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Shoulder Arthropathy Associated With Other Conditions, Shoulder Arthritis
Microcurrent Dressing to Treat Infections, Before, During and After Surgery
Deep periprosthetic infection following total joint arthroplasty is a major complication. Although it only occurs in a small percentage of patients (~1%), it results in substantial morbidity and a decline in functional outcome.
- Conditions
- Shoulder Arthropathy Associated With Other Conditions, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Pain
- Trial name
- NCT03156543
- Testing
- Jumpstart Dressing, Standard Dressing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Painful Osteoarthritis of the Knee
Radiofrequency Ablation of Genicular Nerves for Advanced Osteoarthrosis of the Knee Joint 1 Year Follow-up.
Pharmacological treatment of pain due to osteoarthritis of the knee often proves to be inadequate and/or cause intolerable side effects.
- Trial name
- NCT02688543
- Testing
- RF treatment, radiofrequency ablation, ultrasound
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital General de Jerez de la Frontera
Knee Osteoarthrosis
Participants With Knee Osteoarthrosis
Title: Efficacy and Safety Trial of PRP and ICQ for Elderly Women with KOA Goal: To assess if PRP and ICQ reduce symptoms and improve mobility in elderly women with knee osteoarthritis.
- Trial name
- KOA (NCT06535425)
- Testing
- Platelet-Rich Plasma, Isometric Contractions of Quadriceps, Platelet-Rich Plasma Combined with Isometric Contractions of Quadriceps
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Chengdu Sport University
Knee Osteoarthritis
Shock Wave Versus Iontophoresis in Treatment of Subjects With Knee Osteoarthritis
Both extra corporeal shock wave and dexamethasone iontophoresisare effective in treatment of knee osteoarthritis but which one is more effective is not clear yet .
- Trial name
- Shockwave (NCT04731350)
- Testing
- radial extracorporeal shock wave, iontophoresis, Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Osteoarthritis, Rheumatoid Arthritis
Healthier Living With Arthritis Online Program
Individuals with with arthritic conditions (rheumatoid arthritis, osteoarthritis, or fibromyalgia) and internet and email access were randomized to receive an internet-based arthritis self-management program (treatment group) or…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Fibromyalgia
- Trial name
- NCT00398255
- Testing
- self-management program
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Stanford University
Inflammatory and Non-inflammatory Bone and Joint Diseases
"Translating Articular Biomarkers Into Diagnoses"
Early diagnosis is a key factor in the prevention and management of rheumatic diseases. Rheumatic diseases are classically diagnosed based on criteria combining clinical, biological and radiological features.
- Trial name
- ARTBioSes (NCT06312943)
- Testing
- Collection of joint fluid or tissue sample
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis, Hip
Effects of Grade III Traction-mobilization in End-range Joint Position in Patients With Hip Osteoarthritis
Lower limb osteoarthritis is a major health problem in the westernized countries. The current gold standard treatment is joint replacement.
- Trial name
- NCT02469025
- Testing
- Manual caudal traction mobilization in resting position, Manual caudal traction mobilization in end range position, Selftreatment
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Zaragoza
Osteoarthritis
Saline-Controlled Study of nSTRIDE APS for Knee Osteoarthritis
A double-blind, multicenter, randomized, controlled trial (RCT) that will evaluate the efficacy of a single dose of Autologous Protein Solution (APS) in patients with Osteoarthritis (OA) of the knee.
- Trial name
- PROGRESS IV (NCT02905240)
- Testing
- nSTRIDE APS, Saline
- Where
- 27 sites in United States
- Volunteers
- 332 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Study to Evaluate the Efficacy and Safety of Intra-articular DA-5202 in Patients With Osteoarthritis of the Knee
This Phase II clinical study is to evaluate the efficacy and safety of DA-5202 in patients with osteoarthritis of the knee.
- Trial name
- NCT02554240
- Testing
- DA-5202 20mg, DA-5202 10mg, Na Hyaluronate 20mg
- Where
- South Korea
- Volunteers
- 115 people
- Sponsor
- Dong-A ST Co., Ltd.
Osteoarthritis, Hip Dislocation
Supine Sleeping After Total Hip Replacement
Aim of the current study is to test the non-inferiority hypothesis of differences in early hip dislocation between a group of patients who will be restricted to sleep in supine position and a group without restricted sleeping…
- Trial name
- NCT02107248
- Testing
- Sleep position: no restrictions, Sleep position: supine
- Where
- Netherlands
- Volunteers
- 456 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Hip Osteoarthritis
Obesity's Impact on the Effect of Hip Arthroplasty
The purpose of this study is to investigate whether there is a correlation between hip arthroplasty patients' preoperative weight and the patients quality of life and the clinical effect one year postoperatively.
- Trial name
- NCT01496716
- Testing
- Hip arthroplasty
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- University of Aarhus
Osteoarthritis
Aerobic Exercise Intervention for Knee Osteoarthritis
This trial will test if walking or bicycling exercise is effective as a non-surgical treatment option for patients with knee osteoarthritis.
- Trial name
- NCT00049816
- Testing
- Walking exercise, Cycling Exercise
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- Mayo Clinic
Knee Osteoarthritis, Total Knee Replacement
Knee Arthroplasty Activity Trial
Total knee replacement (TKR) is a common and costly procedure widely used to relieve pain and improve function in patients with symptomatic advanced knee osteoarthritis (OA).
- Trial name
- KArAT (NCT04107649)
- Testing
- Telephonic Active Coaching (Motivational Interviewing) + Financial Incentives, Wrist based activity tracker wear, Basic Study Activities
- Where
- 5 sites in United States
- Volunteers
- 600 people
- Sponsor
- Brigham and Women's Hospital
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