Clinical trials: Osteoarthritis Arthritis
Osteoarthritis
AMS Study: Inflammatory and Biomechanical Contributors to Arthritis Development Following Arthroscopic Meniscectomy
The purpose of this study is to examine the relationship between muscle activation and heart rate on joint generalized inflammation and arthritis development.
- Trial name
- NCT00752271
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Osteoarthritis
Study of Cartilage Relaxometry and Physical Activity in Osteoarthritis
This study is the radiological component of an earlier registered trial under the title: Efficacy of Exercise on Physical Function and Cartilage Health in Patients With Knee Osteoarthritis.
- Trial name
- NCT01797679
- Testing
- Strength Training, Aerobic Exercise
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Osteoarthritis, Knee
To Evaluate the Efficacy and Safety of Collavant n2 in Individuals With Osteoarthritis of the Knee
A randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of Collavant n2 in individuals with osteoarthritis of the knee.
- Trial name
- NCT05474586
- Testing
- Collavant n2 40 mg/day, Glucosamine hydrochloride & Chondroitin sulfate, Microcrystalline cellulose
- Where
- 10 sites in India
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Osteoarthritis (OA) of the Knee, Fear of Needles
Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?
This study aims to investigate factors that affect the subjective experience of pain during and after intra-articular knee joint injection of steroids by comparing needle gauge size (22 G vs 25 G needles), as well as the presence…
- Trial name
- NCT06865170
- Testing
- 25 gauge needle, 22 gauge needle, +/- Ethyl Chloride Topical Aerosol Anesthetic
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Osteoarthritis, Cardiovascular Risk Factors
Osteoarthritis Cardiovascular Risk Factors
We analyze retrospectively the relationship between traditional cardiovascular risk factors as hypertension, obesity, dislipidemia and diabetes and hand or knee osteoarthritis and we compare the results with a control groups of…
- Conditions
- Osteoarthritis, Cardiovascular Risk Factors, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT01902654
- Testing
- Cardiovascular risk factors diagnoses collection., History of cardiovascular disease, Cardiovascular risk factors association
- Where
- Spain
- Volunteers
- 490 people
- Sponsor
- Parc Taulí Hospital Universitari
Knee Osteoarthritis
Radiofrequency Ablation in the Pain Management of Knee Osteoarthritis
The aim of this study is to assess the safety and efficacy of radio frequency thermo-coagulation on the genicular nerve (RFTGN) and intra-articular pulsed radio frequency (IAPRF) for Knee Osteoarthritis (KOA) to improve physical…
- Trial name
- NCT05303766
- Testing
- Radio-frequency ablation, Intra-articular steroids, Pulsed Radio-frequency
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Osteoarthritis, Hip
Whole Blood Metal Ion Concentrations in Metal-on-metal Total Hip Arthroplasty and Hip Resurfacing
The investigators aimed to investigate the possible differences in metal ion concentrations in patients following one of two types of metal-on-metal articulating hip prosthesis regarding chromium and cobalt concentration…
- Trial name
- NCT04585022
- Testing
- Magnum, Zimmer Biomet, Warsaw, IN, Recap, Zimmer Biomet, Warsaw, IN
- Volunteers
- 75 people
- Sponsor
- Hvidovre University Hospital
Knee Osteoarthritis
Efficacy of AI-Driven and Traditional Physical Therapy Programs in Patients With Knee Osteoarthritis
This study aims to compare the effectiveness of an artificial intelligence (AI)-guided physical therapy program with a traditional physical therapy program in patients with knee osteoarthritis.
- Trial name
- NCT07774195
- Testing
- AI-Guided Physical Therapy Program, Traditional Physical Therapy Program, Lifestyle Modification and Joint Protection Education
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Monocompartimental Tibiofemoral Osteoarthritis, Osteoarthritis
Evaluation of the Use of Tranexamic Acid in Tibial Osteotomies
A randomised controlled double-blind clinical trial focused on the evaluation of the effectiveness of the tranexamic acid on bleeding, pain and wound complications reduction in tibial osteotomies.
- Trial name
- NCT04785651
- Testing
- Tibial osteotomy with Tranexamic acid, Tibial osteotomy without Tranexamic acid
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis
A Study of the Patterns of Use of Etoricoxib in France (MK-0663-148)
This postmarketing study will examine the use of etoricoxib (Arcoxia®) in routine clinical practice in France as well as the use of celecoxib (Celebrex®).
- Trial name
- COXIBUS (NCT01572675)
- Testing
- etorocoxib, celecoxib
- Volunteers
- 547 people
- Sponsor
- Organon and Co
Osteoarthritis, Rheumatoid Arthritis
Total Knee Replacement With the ROCC Knee
The purpose of this study was to assess the results of a Total Knee prosthesis specifically intended to enhance functional performance , especially in terms of physical and sports activity.
- Trial name
- NCT02127619
- Testing
- Total knee replacement with the ROCC® knee prosthesis
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Bercovy, Michel, M.D.
Knee Osteoarthritis
Pre-emptive Effect of Duloxetine in the Second Knee in Staged Total Knee Arthroplasty
In Korea, the interval between knee arthroplasties is usually 1 week. According to previous studies, when total knee arthroplasty was performed at 1-week intervals, total bleeding was reduced and the period of hospital stay was…
- Trial name
- NCT03792828
- Testing
- Duloxetine HCl 30mg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Osteoarthritis, Knee
Is Phonophoresis Treatment Effective?
The specimens from patients as knee osteoarthritis diagnosed who was applied ibuprofen phonophoresis will be analyzed.
- Trial name
- NCT02358707
- Testing
- Ibuprofen phonophoresis
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Cukurova University
Osteoarthritis, Knee
Efficacy and Mechanism of FSN Treatment for Senile Knee Osteoarthritis
The goal of this clinical trial is to compare FSN with oral Nonsteroidal Antiinflammatory Drugs (NSAIDs) in pain relief and improvement in knee function among elder people, the main questions it aims to answer are: Q1: Compared…
- Trial name
- NCT06328153
- Testing
- Fu's Subcutaneous Needling, Celecoxib
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Knee Osteoarthritis
Effectiveness of Using a Chatbot to Promote Adherence to Home Physiotherapy
A Chatbot oriented to virtually assist patients in a physiotherapy treatment has been designed and developed to interact with patients with musculoskeletal disorders in need for domiciliary rehabilitation.
- Trial name
- NCT05363137
- Testing
- Chatbot Assistant, Standard care
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- University of Valencia
Osteoarthritis, Knee, Knee Replacement
Prediction of Outcomes Following Total Knee Replacement- Pilot
This study seeks to examine multiple risk factors as predictors of pain and function following total knee arthroplasty (TKA). Risk factors will be measured pre-surgically using psychophysical testing procedures, multimodal…
- Trial name
- POKR-p (NCT04328701)
- Testing
- Mindfulness-based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Brigham and Women's Hospital
Knee Osteoarthritis
Pilot Synovial Fluid Molecular/Stem Cell Response to PRP in Knee Osteoarthritis: Clinical & Imaging Outcome Correlation
The purpose of this study is to evaluate the affect that platelet rich plasma has on the molecular an cellular functioning of the knee joint.
- Trial name
- NCT02468492
- Testing
- Platelet Rich Plasma, Normal Saline
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Knee Osteoarthritis
The Effect of Intrinsic Focus on Gait Cycle and the Possible Confounding Effect of Noise in Patients With Knee Osteoarthritis
Patients with knee osteoarthritis may develop an antalgic gait over time due to pain in the knee, characterized by a decrease in the stance phase and stride length on the painful side.
- Trial name
- NCT06065410
- Testing
- Baseline, Intrinsic focus, White noise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University
Osteoarthritis, Knee, Pain
A Study to Evaluate ONO-4474 in Patients With Pain Due to Osteoarthritis of the Knee
The purpose of this phase 2, randomised, double-blind, placebo controlled, parallel group, multicentre study is to investigate the efficacy, safety, tolerability and pharmacokinetics of a compound ONO-4474 in patients with…
- Trial name
- MOTION (NCT02997696)
- Testing
- ONO-4474
- Where
- 47 sites in Denmark, Hungary and 3 more
- Volunteers
- 70 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Knee Osteoarthritis
Balance Training Using Biodex Stability System in Knee Osteoarthritis.
This was a randomized control Trial, conducted with two group of patients, one has received Balance and stability training on Biodex stability system along with conservative protocol of traditional exercises.
- Trial name
- NCT04019366
- Testing
- Balance Training, Conventional Training
- Where
- Pakistan
- Volunteers
- 43 people
- Sponsor
- Riphah International University
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