Clinical trials: Osteoarthritis Arthritis
Osteoarthritis of the Knee
Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee
The purpose of this trial is to investigate the efficacy and safety of OLT1177 Gel in subjects with moderate to severe pain associated with osteoarthritis of the knee following cessation of pain therapy.
- Trial name
- NCT01768975
- Testing
- OLT1177 Gel
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Olatec Therapeutics, Inc.
Thumb Osteoarthritis
Proprioceptive Thumb Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Trial name
- thumb (NCT04738201)
- Testing
- Proprioceptive thumb exercises.
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Malaga
Osteoarthritis,Knee
Can 3D Kinematic Parameters Assess the Symptomatic and Functional Severity of KOA?
There is little study focusing on kinematic parameters in the assessment of the symptomatic and functional severity of knee osteoarthritis (KOA).
- Trial name
- NCT03011112
- Testing
- Observational procedure
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Hip Osteoarthritis, Arthropathy of Hip
PENG Block vs PENG Plus Periarticular Injection vs Periarticular Injection in Older Adults
Pain after hip surgery is common in older adults and may limit early mobilization, increase the need for opioid medications, and contribute to complications such as delirium, nausea, or prolonged hospital stay.
- Trial name
- NCT07327892
- Testing
- Pericapsular Nerve Group (PENG) Block, Periarticular Injection (PAI)
- Where
- Poland
- Volunteers
- 108 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis
Evaluation of Acetabular Perfusion After Ganz Osteotomy by Positron Emission Tomography
The purpose of this study is to examine the blood flow in acetabulum after periacetabular osteotomy by Positron Emission Tomography (PET).
- Trial name
- NCT00119444
- Testing
- Periacetabular osteotomy
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Osteoarthritis, Rheumatoid Arthritis
Exceed ABT Acetabular Cup Cementless System
A Post-market Clinical Follow-up Study to provide safety, performance and clinical benefits data on the Exceed ABT acetabular cup (implants and instruments) when used in combination with ceramic liners or polyethylene…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Correction of Functional Deformity
- Trial name
- NCT04255394
- Volunteers
- 677 people
- Sponsor
- Zimmer Biomet
Osteoarthritis of the Knee
A Randomized, Controlled Study to Evaluate Efficacy and Safety of Intra-articular Ampion for Osteoarthritis Pain in Knee
This study will evaluate the efficacy of an Intra-Articular Injection of Ampion™ in Adults with pain due to osteoarthritis of the knee.
- Trial name
- NCT02024529
- Testing
- 4 mL injection of Ampion
- Volunteers
- 538 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Osteoarthritis
Surgery Versus no Surgery for OA of the Knee
The purpose of this trial is to evaluate the effectiveness of arthroscopy (lavage and debridement) in conjunction with the best available non-surgical treatment versus the best available non-surgical treatment alone (medication…
- Trial name
- NCT00158431
- Testing
- Arthroscopy plus Medical Management, Medical Management
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- Fowler Kennedy Sport Medicine Clinic
Osteoarthritis, Hip
Conservative Treatment for Hip Osteoarthritis
The purpose of the study is to evaluate the effect of manual treatment and a patient education programme for patients without indication for hip surgery.
- Trial name
- COHART (NCT01039337)
- Testing
- Hip School, Hip School and Manual Treatment, Minimal control intervention
- Where
- Denmark
- Volunteers
- 118 people
- Sponsor
- Nordic Institute of Chiropractic and Clinical Biomechanics
Knee Osteoarthritis
Improvement in Pain and Function Following a Physiotherapy Program in Older Adults With Knee Osteoarthritis
This study evaluates the combination of a therapeutic exercise program and dry needling in the treatment of knee osteoarthritis in older adults.
- Trial name
- NCT02698072
- Testing
- Therapeutic exercise, Dry needling
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Gonarthrosis, Coxarthrosis
Radiotherapy 3 vs 6 Gy in Gonarthrosis and Coxarthrosis
This is a non-inferiority study in which the investigators compare two low-dose radiotherapy schemes, which are recommended from DEGRO Clinical Practice Guidelines (3 Gy vs 6 Gy) for the treatment of osteoarthritis and other…
- Trial name
- RAGOCO (NCT04424628)
- Testing
- Low dose radiotherapy A, Low dose radiotherapy B
- Where
- Spain
- Volunteers
- 338 people
- Sponsor
- Fundacion GenesisCare
Osteoarthritis, Insomnia
Insomnia and Osteoarthritis Study
This research is being done to evaluate the effects of a sleeping pill (eszopiclone, Lunesta)in patients with arthritis of the knee who also suffer from chronic insomnia.
- Trial name
- NCT00374556
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Knee Osteoarthritis
Neuro-muscular Exercise Training Verses Quadriceps Training in Mild to Moderate Knee Osteoarthritis
A randomized controlled trial in which Neuro-muscular exercise training and Isolated quadriceps training program would be applied on patients with symptomatic knee Osteoarthritis by using different tools and changes would be…
- Trial name
- NCT03798002
- Testing
- Neuro-muscular exercise training Group, quadriceps training program
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Osteoarthritis of the Knee
Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee
Efficacy and safety of Imotun capsule in osteoarthritis of the knee
- Trial name
- ABSOLUTE-R (NCT01756937)
- Testing
- Imotun
- Where
- 9 sites in South Korea
- Volunteers
- 287 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Back Pain, Coronary Artery Disease
Detecting and Addressing Preclinical Disability
The Physical Functioning Inventory (PFI) is a standardized patient reported outcome measure that assesses preclinical disability.
- Conditions
- Back Pain, Coronary Artery Disease, Chronic Obstructive Pulmonary Disease, Diabetes
- Trial name
- NCT01979081
- Testing
- Tailored advice from a physiotherapist and/or an occupational therapist through the myOSCAR patient portal
- Where
- Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- McMaster University
Osteoarthritis, Knee
VItamin D Effect on Osteoarthritis Study
Observational evidence suggests that vitamin D deficiency may have a role in the causes of osteoarthritis (OA) and there are biologically plausible mechanisms to explain this.
- Trial name
- VIDEO (NCT01176344)
- Testing
- Vitamin D
- Where
- 2 sites in Australia
- Volunteers
- 413 people
- Sponsor
- Menzies Institute for Medical Research
Bone Malalignment
CT Imaging Study for Knee Osteotomy (CISKO)
Malalignment of the knee joint causes arthritis in later life. Currently there are three surgical ways to treat knee arthritis: total knee replacement, partial knee replacement, and high tibial osteotomy (HTO).
- Trial name
- CISKO (NCT02717845)
- Testing
- Ellipse, Tomofix
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- North Cumbria University Hospitals NHS Trust
Osteoarthritis, Knee, Arthritis of Knee
Treatment of Knee Osteoarthritis With Allogenic Mesenchymal Stem Cells
In this study we want to evaluate the clinical use of allogenic mesenchymal stem cells (MSC), obtained from bone marrow of healthy donors, for treatment of knee osteoarthritis.
- Conditions
- Osteoarthritis, Knee, Arthritis of Knee, Knee Osteoarthritis
- Trial name
- MSV_allo (NCT01586312)
- Testing
- Allogenic mesenchymal stromal cells injection, Hyaluronic Acid
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Red de Terapia Celular
Pain, Acute, Knee Osteoarthritis
Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphenous Block and IPACK in Total Knee Replacement Surgery.
Total knee replacement surgery is associated with significant pain in the immediate postoperative period, especially in movement. In turn, this is associated with more subsequent chronic pain.
- Conditions
- Pain, Acute, Knee Osteoarthritis, Anesthesia
- Trial name
- NCT06514365
- Testing
- IPACK block with Bupivacaine 0.25% with adrenaline
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Germans Trias i Pujol Hospital
Necrosis of Femoral Head, Knee Osteoarthritis
Ketamine Prevent POCD
Previous study demonstrated that neuroinflammation induced by surgery is the main cause of the postoperative cognitive dysfunction. As an agonist of NMDA receptor, ketamine is proved to be an anti-inflammation agent.
- Trial name
- KPPOCD (NCT02220400)
- Testing
- Ketamine
- Where
- 3 sites in China
- Volunteers
- 484 people
- Sponsor
- RenJi Hospital
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