Clinical trials: Osteoarthritis Arthritis
Osteoarthritis, Osteoarthritis Finger
Effects of Using Custom Photobiomodulation Therapy for the Treatment of Osteoarthritis of the Fingers and Rhizarthrosis
Osteoarthrosis (OA), a multifactorial degenerative process, is responsible for joint pain and functional limitation. In the hand, more specifically in the proximal and distal interphalangeal joints of the fingers, it is one of…
- Conditions
- Osteoarthritis, Osteoarthritis Finger, Osteoarthritis Hand, Osteoarthritis Both Hands
- Trial name
- NCT05041231
- Testing
- Photobiomodulation therapy (PBT)
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Vita Care
Knee Osteoarthritis
Functional Recovery After Total Knee Arthroplasty
Total knee replacement is one of the most successful surgical procedures in Orthopaedics. However, 10-20% of the patients are still dissatisfied with the results of the surgery.
- Trial name
- NCT02156453
- Testing
- Total knee arthroplasty
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Knee Osteoarthritis
Self-administered Acupressure for Knee Osteoarthritis: A Pilot Randomized Controlled Trial
Objectives: To test the feasibility of the study design and clinical effects of self-administered acupressure on relieving knee osteoarthritis (OA) pain.
- Trial name
- NCT03155737
- Testing
- Self-acupressure, Knee health education
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- The Hong Kong Polytechnic University
Osteoarthritis, Total Knee Arthroplasty
Antero-Posterior Knee Stability
A retrospective one-time evaluation of total knee patients one year or more postoperative, to compare antero-posterior (AP) stability with the TELOS Stress device/stress x-rays and clinical outcomes.
- Conditions
- Osteoarthritis, Total Knee Arthroplasty, Stability, Knee Osteoarthritis
- Trial name
- NCT03387839
- Testing
- Stress X-Ray
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- David F. Scott, MD
Knee Osteoarthritis
Evaluation of Safety and Exploratory Efficacy of an Autologous Adipose-derived Cell Therapy Product for Treatment of Single Knee Osteoarthritis
The objective of this clinical study is to evaluate the safety of an intraarticular injection of an investigational biologic product (IBP), PSC-01, the patient's own adipose-derived stromal vascular fraction cells (SVF) extracted…
- Trial name
- NCT04043819
- Testing
- PSC-01
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Personalized Stem Cells, Inc.
Osteoarthritis, Knee
Use of Fresh Platelet Rich Plasma With Concentrated Leukocytes or Fresh Platelet Rich Plasma Without Concentrated Leukocytes in the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial
The aim of the study is to compare the triple infiltration of Fresh Platelet Rich Plasma with concentrated Leukocytes against triple infiltration of Fresh Platelet Rich Plasma Without Concentrated Leukocytes in the treatment of…
- Trial name
- PRP019 (NCT04187183)
- Testing
- Fresh Platelet Rich Plasma with leukocyte, Fresh Platelet Rich Plasma without leukocyte
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis, Knee
Evaluation of the TruMatch® System in Knee Prosthetic Surgery
Patient specific instrumentation is an alternative to conventional intra- and extra-medullary guides to perform the femoral and tibial cuts in total knee replacement (TKR).
- Trial name
- NCT01876654
- Testing
- TruMatch® patient specific cutting guide
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Milan
Osteoarthritis, Knee
The Efficacy of TGF for Treating Osteoarthritis of the Knee
This study is to evaluate the efficacy of herbal formula TGF treating knee joint osteoarthritis(KOA) and its biochemical mechanism.
- Trial name
- NCT03562429
- Testing
- TGF, TGFP
- Volunteers
- 180 people
- Sponsor
- China Medical University Hospital
Osteoarthritis of the Hip
Physical Therapy Prior to Total Knee Replacement
In this study, the investigators are investigating the effects of physical therapy (PT) for treating high grade knee osteoarthritis (OA) in patients that are candidates for total knee replacement.
- Trial name
- NCT02279277
- Testing
- Supervised physical therapy program prior to total knee replacement surgery
- Volunteers
- 148 people
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis, Knee
Immediate Effects of rTMS on Excitability of the Quadriceps With Knee Osteoarthritis
The purpose of the study is to identify things that influence the ability to "turn on" the thigh muscle (quadriceps). The thigh muscle tends to be under active with knee osteoarthritis, which may make it difficult to strengthen…
- Trial name
- NCT02881775
- Testing
- rTMS and exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Knee Osteoarthritis
Comparing Efficacy of PRP Combined With Different Hyaluronan for the Treatment of Knee Osteoarthritis
Either PRP or HA is each effective for treating knee OA. However, the efficacy of combined PRP and HA injections remains unknown clinically.
- Trial name
- NCT04931719
- Testing
- PRP+Artz group, PRP+ HYAJOINT Plus group
- Where
- Taiwan
- Volunteers
- 95 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Osteoarthritis of the Hand
AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint
This study will evaluate the safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the basal thumb joint.
- Trial name
- NCT02762760
- Testing
- AMPION™, Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Wrist Arthritis, Wrist Osteoarthritis
Study of Wrist Fusions With the Medartis Aptus Arthrodesis Plate
The primary working hypothesis of this study is whether wrist arthrodesis leads to an improvement in functional status in both rheumatoid arthritis and post-traumatic osteoarthritis.
- Trial name
- STIF (NCT05875896)
- Testing
- Total wrist fusion
- Where
- Germany
- Volunteers
- 73 people
- Sponsor
- Waldfriede Hospital
Complex Regional Pain Syndromes, Fibromyalgia
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
Motor neglect describes a loss of function without a loss of strength, reflexes or sensation. Motor neglect has been described in patients with traumatic brain injury, stroke and chronic pain conditions, e.g.
- Conditions
- Complex Regional Pain Syndromes, Fibromyalgia, Stroke, Traumatic Brain Injury
- Trial name
- VERMONT (NCT03887962)
- Testing
- Virtual Environment Biofeedback, Treadmill walking with no Virtual Environment Biofeedback
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Low Back Pain, Migraine
Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain
The purpose of this study is to evaluate the safety and tolerability of OraVescent fentanyl for the potential treatment of breakthrough pain episodes in patients who have chronic noncancer pain.
- Conditions
- Low Back Pain, Migraine, Diabetic Neuropathies, Osteoarthritis
- Trial name
- NCT00228605
- Testing
- OraVescent Fentanyl
- Where
- 38 sites in United States
- Volunteers
- 500 people
- Sponsor
- Cephalon
Arthritis, Osteoarthritis Hand
Novel Splinting Technique Using 3D Models
The purpose of the study is to determine the feasibility of a non-contact custom splint fabrication method for patients with chronic diseases suffering from hypersensitive skin or compromised skin integrity.
- Conditions
- Arthritis, Osteoarthritis Hand, Scleroderma, Systemic, Scleroderma, Diffuse
- Trial name
- NCT05351060
- Testing
- Custom Fabricated Splint
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Giovanna Fichera
Osteoarthritis, Hip, Osteoarthritis, Knee
Study on Costs and Effects of Waiting Time in Total Hip and Knee Replacements
The aim of this study is to compare the cost-effectiveness of major joint replacement in patients with short and non-fixed (control group) waiting time (WT).
- Trial name
- NCT00294424
- Testing
- Short waiting time, Non-fixed waiting time
- Where
- Finland
- Volunteers
- 833 people
- Sponsor
- Academy of Finland
Osteoarthritis
ORCA Study: Osteoarthritis and Risks Associated With the Consumption of NSAIDs
Cross-sectional epidemiological study in patients with diagnosis of osteoarthritis (OA) in order to evaluate risk factors associated with the use / prescription of non-steroidal anti-inflammatory drugs (NSAID).
- Trial name
- ORCA (NCT04099459)
- Where
- Colombia
- Volunteers
- 1,250 people
- Sponsor
- Scandinavia Pharma
Osteoarthritis, Knee
Technology and System for Minimally Invasive TKA Surgery Robot
Developed a robot for minimally invasive TKA surgery and prepare for the subsequent CFDA application of the minimally invasive total knee replacement robot system.
- Trial name
- NCT04953988
- Testing
- Robotic TKA, Manual operation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Osteoarthritis Hand
Use of Allograft Adipose Matrix for Small Joint Arthritis of the Hand
The purpose the research is to evaluate the safety and efficacy of injection of adipose allograft matrix (AAM) to the small joints of the hand for treatment of early stage osteoarthritis.
- Trial name
- NCT05747469
- Testing
- local anaesthetic injection, Human Adipose Allograft
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
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