Clinical trials: Osteoarthritis Arthritis
Knee Osteoarthritis
Optimal Articular Solutions With Intraosseous and Synovial Platelet-Rich Plasma
This is a prospective cohort clinical study. Due to logistic constraints at the sites of implementation, a randomized allocation will not be feasible (private clinic).
- Trial name
- OASIS-PRP (NCT06520059)
- Testing
- Platelet rich-plasma - PRP - intraosseous and intra-articular admnistration
- Where
- 2 sites in Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
KNEE OSTEOARTHRITIS
Evaluate Efficacy and Safety of X0002 in Treatment of Knee Osteoarthritis
This study is a randomized, double-blind clinical trial in a Chinese population.
- Trial name
- NCT03691818
- Testing
- X0002 Spray, Ibuprofen Tablet
- Where
- China
- Volunteers
- 353 people
- Sponsor
- Tianjin XinChen-Techfields Pharma Co., LTD.
Calcaneocuboid Osteoarthritis Secondary to Trauma
Calcaneocuboid Arthrodesis in Triple Arthrodesis by Plate Versus Screw: Randomized Controlled Trial
Investigators aim to compare clinical and radiological outcome of use of plate versus screw fixation for calcaneocuboid arthrodesis in adult population.
- Trial name
- NCT06003296
- Testing
- Calcaneocuboid arthrodesis
- Where
- Egypt
- Volunteers
- 3 people
- Sponsor
- Assiut University
Total Knee Replacement, Virtual Reality Therapy
Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty
The aim of this study is to assess the efficacy of virtual rehabilitation through the Virtual Reality Rehabilitation System (VRRS) versus traditional rehabilitation improving the functional outcomes after primary Total Knee…
- Conditions
- Total Knee Replacement, Virtual Reality Therapy, Osteoarthritis, Knee Arthroplasty
- Trial name
- NCT02413996
- Testing
- Kinetec® knee continuous passive motion (CPM ), Functional activities, VRRS rehabilitation
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Knee Osteoarthritis, Falls
Effects of Tele Rehabilitation vs Onsite Rehabilitation on Balance, Mobility, and Risk of Fall Among Geriatric Population With Knee Osteoarthritis
This randomized controlled trial aims to determine the effects of telerehabilitation versus onsite rehabilitation on balance, mobility, and risk of fall among geriatric patients with knee osteoarthritis (KOA).
- Conditions
- Knee Osteoarthritis, Falls, Balance Impairment, Mobility Limitation
- Trial name
- NCT07798973
- Testing
- Telerehabilitation, Onsite Rehabilitation
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Ibadat International University, Islamabad
Primary; Coxarthrosis
Gait Initiation and Transition From Double to Single Support in Patients With Unilateral Primary Coxarthrosis
The study consists to evaluate the impact of prosthetic surgery (PTH and RTH) on kinematic and dynamic parameters (joint torques) of the lower limbs during gait initiation in patients with primary coxarthrosis.
- Trial name
- COXAM (NCT06258369)
- Testing
- Patients with primary coxarthrosis (any stage)., Patients with primary coxarthrosis (any stage) and operated with Total Hip Prosthesis (THP)., Patients with primary coxarthrosis (any stage) and operated with RTH (Hip resurfacing).
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Lille Catholic University
Osteoarthritis (OA) of the Knee
2ccPA Study in Patients With Symptomatic Knee Osteoarthritis
This clinical trial is designed to determine safety and tolerability as well as the MTD of a single-dose 2ccPA and PK data in symptomatic knee OA.
- Trial name
- NCT04229394
- Testing
- 2ccPA
- Where
- 5 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- Orient Europharma Co., Ltd.
Osteoarthritis
Effects of Transcutaneous Electrical Nerve Stimulation on Pain and Disability in Patients With Osteoarthritis
The purpose of this study is to determine the effects of transcutaneous electrical nerve stimulation (TENS) on pain and mobility by comparing different stimulation sitesP: 1. the location with the lowest resistance 2.
- Trial name
- NCT01137266
- Testing
- TENS
- Where
- Netherlands
- Volunteers
- 72 people
- Sponsor
- Maxima Medical Center
Lumbar Osteoarthritis, Spondylosis
Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes
Patients undergoing spine surgery often have considerable pain post-operatively and frequently require opioid medication (Percocet, Norco, oxycodone, morphine, etc.) to control their pain postoperatively.
- Conditions
- Lumbar Osteoarthritis, Spondylosis, Lumbar Disc Disease, Spinal Stenosis
- Trial name
- NCT02700451
- Testing
- Ketorolac, Acetaminophen
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis of Knees
The Effectiveness of Arthroscopic Cartilage Regeneration Facilitating Procedure for Patients With Knee Osteoarthritis
The aim of this study is to discuss the effect of gait pattern in patients receiving arthroscopic cartilage regeneration facilitating procedure (ACRFP) for treatment of osteoarthritis of knees.
- Trial name
- NCT03452423
- Testing
- ACRFP
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Osteoarthritis (OA) of the Knee
The Efficacy of Transcutaneous Pulsed Radiofrequency Acupuncture for Knee Osteoarthritis
Efficacy of transcutaneous acupoint pulsed radiofrequency with rehabilitation for knee osteoarthritis.
- Trial name
- NCT06702046
- Testing
- transcutaneous pulsed radiofrequency acupuncture
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Osteoarthritis, Knee, Arthropathy of Knee
Post-operative Rehabilitation of Total Knee Arthroplasty With Applications on Smart Phone
This study is designed to estimate the effect of an application on rehabilitation for osteoarthritis patients after total knee arthroplasty.
- Trial name
- NCT03365427
- Testing
- APP
- Volunteers
- 200 people
- Sponsor
- Peking University People's Hospital
Osteoarthritis of the Knee
Genicular Radiofrequency Ablation for Unilateral Knee Arthroplasty Pain Management
Three primary reasons prolong hospital stays following unilateral knee arthroplasty. Pain is the primary reason followed by opioid drowsiness and nausea/vomiting side effects.
- Trial name
- RFA (NCT02925442)
- Testing
- t-RFA, C-RFA, Control
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lyman Medical Research Foundation, Inc.
Osteoarthritis of Knee Joint
Comparative Clinical Trial of Lornoxicam to Diclofenac in Patients of Osteoarthritis of Knee Joint.
The purpose of this study was to compare the pain relieving action of the lornoxicam and diclofenac in patients of OA knee.
- Trial name
- NCT01055470
- Testing
- Diclofenac, Lornoxicam
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Government Medical College, Bhavnagar
Gonarthrosis, Low Back Pain
Ketorol Gel in Gonarthrosis and Low Back Pain
Comparative clinical study of Ketorolac tromethamineand Ketoprofen gel in patients with Gonarthrosis and Low back pain.
- Trial name
- NCT02638831
- Testing
- Ketorolac Tromethamine, Ketoprofen
- Volunteers
- 240 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Osteoarthritis, Knee
A Controlled Study of an Herbal Topical Patch in Treating Osteoarthritis (OA) of the Knee
An evaluation of the safety and efficacy of an herbal patch in treating osteoarthritis pain of the right or left knee.
- Trial name
- NCT01183624
- Testing
- Herbal Patch
- Where
- 12 sites in China
- Volunteers
- 626 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Knee Osteoarthritis
Efficacy of Radial Shockwave Therapy for Treatment of Pain in Knee Osteoarthritis
The objective of this study is to compare the results of 2000 impulses of radius shockwaves per week with 2000 placebo shockwaves on the treatment of pain and functional incapacity of patients with severe primary knee…
- Trial name
- NCT02197962
- Testing
- Extracorporeal Radial shockwaves
- Where
- 2 sites in Brazil
- Volunteers
- 105 people
- Sponsor
- Marta Imamura
Osteoarthritis, Inflammatory Arthritis
Ultrasound Guided vs Unguided Intra-articular Knee Injections
To determine the accuracy of unguided versus ultrasound (US) guided knee joint injections in obese patients with no clinically detectable effusion.
- Trial name
- NCT02092246
- Testing
- Ultrasound machine, Unguided injection
- Where
- United States
- Sponsor
- Mayo Clinic
Osteo Arthritis Shoulders, Osteoarthritis Shoulder
Endogenous Pain Modulation Study
Rationale: Although most patients experience significant pain relief after total shoulder arthroplasty (TSA), pain persists for some patients even after surgery.
- Trial name
- EPM (NCT05861960)
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Knee Osteoarthritis
Effects of Agility and Perturbation Based Training in Addition to Routine Physical Therapy
Osteoarthritis is a degenerative joint disease. Knee OA patients sometimes report episodes of knee instability that limit their ADLs. The episodes of instability are similar to those reported in knee ligament injuries.
- Trial name
- NCT06460662
- Testing
- Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
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