Clinical trials: Osteoarthritis Arthritis
Osteo Arthritis Knee
Geniculate Artery Embolization for Knee Pain Secondary to Osteoarthritis (OA)
Purpose: To evaluate embolization as a treatment for OA related knee pain versus placebo to demonstrate the actual effect of embolization on pain and disability.
- Trial name
- NCT03362957
- Testing
- Geniculate Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- University of North Carolina, Chapel Hill
Hip Osteoarthritis, Anesthesia, Local
LPB Combined with QLB Using Single-needle Technique (LPQLB-SNT) for Hip Arthroplasty
Total hip arthroplasty (THA) is one of the most successful orthopedic procedures to effectively relieve pain and restore function in patients with hip osteoarthritis, osteonecrosis of femoral head and hip fracture.The Lumbar…
- Conditions
- Hip Osteoarthritis, Anesthesia, Local, Hip Fractures, Osteonecrosis of Femoral Head
- Trial name
- LPQLB-SNT (NCT04266236)
- Testing
- L3 LPB, L4 LPB, T12 block
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai 6th People's Hospital
Osteoarthritis, Knee
VItamin D Effect on Osteoarthritis Study
Observational evidence suggests that vitamin D deficiency may have a role in the causes of osteoarthritis (OA) and there are biologically plausible mechanisms to explain this.
- Trial name
- VIDEO (NCT01176344)
- Testing
- Vitamin D
- Where
- 2 sites in Australia
- Volunteers
- 413 people
- Sponsor
- Menzies Institute for Medical Research
Osteoarthritis (OA) of the Knee
Collagen-PVP vs Hylan G-F 20 in the Treatment of Knee Osteoarthritis
Abstract Title: "Efficacy of intra-articular polyvinylpyrrilidone collagen in the treatment of Kellgren-Lawrence grade II-III primary knee osteoarthritis compared to Hilano G-F 20: a controlled clinical trial." Investigators…
- Trial name
- 26092023 (NCT07692009)
- Testing
- Collagen-polyvinylpyrrolidone, Hylan G-F 20
- Where
- Mexico
- Volunteers
- 32 people
- Sponsor
- Centro Multidisciplinario para el Desarrollo Especializado de la Investigacion Clinica en Yucatan S.
Peripheral Arterial Disease, Claudication
THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease
The purpose of this study is to understand the effects of fish oil supplement (containing parts of omega-3 fatty acids) on inflammation.
- Conditions
- Peripheral Arterial Disease, Claudication, Claudication, Intermittent, Vascular Occlusion
- Trial name
- NCT02719665
- Testing
- SPM Emulsion, Dose-modality, SPM Softgel, Dose-Modality
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Knee Osteoarthritis
The Effect of Postoperative "Peanut Ball" Rehabilitation After Total Knee Replacement.
The purpose of this randomized controlled study is to evaluate the effect of postoperative exercise with a "peanut ball" after total knee replacement, on pain, intake of pain killers, knee function, and health-related quality of…
- Trial name
- NCT05137834
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Ankle Fractures, Intra-Articular Fractures
Prevention of Posttraumatic Osteoarthritis After Acute Intraarticular Fractures
Intra-articular fracture is a very common fracture. The only method to treat these fractures is surgery with plate and screws followed by rehabilitation.
- Conditions
- Ankle Fractures, Intra-Articular Fractures, Osteoarthritis
- Trial name
- NCT03769909
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Degenerative Lumbar Spinal Stenosis, Facet Joint Arthrosis
Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases
The purpose of this multi-center, randomized, clinical study is to show that the treatment of degenerative lumbar spine with high- or mid-flex rods is not inferior to the treatment with low-flex rods in terms of clinical and…
- Conditions
- Degenerative Lumbar Spinal Stenosis, Facet Joint Arthrosis, Spondylarthritis, Discopathy
- Trial name
- NCT06320899
- Testing
- SpineShape System IV straight rod elastic, SpineShape System IV straight rod medium, SpineShape System IV straight rod stiff
- Where
- 2 sites in Switzerland
- Volunteers
- 126 people
- Sponsor
- SpineSave AG
Knee Osteoarthritis
Factors Predicting the Duration of Effectiveness of Viscosupplementation in Knee Arthosis
Knee osteoarthritis is a frequent condition whose prevalence is estimated at 7.6% of the French population aged 40 to 75, or approximately 2 million individuals .
- Trial name
- PRESAGE (NCT04988698)
- Testing
- none intervention
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Hopital Nord Franche-Comte
Osteoarthritis
Effects of Oral Salmon Calcitonin in Human Osteoarthritis
To assess the safety, tolerability and clinical efficacy of oral salmon calcitonin in patients suffering from osteoarthritis
- Trial name
- NCT00376311
- Testing
- oral salmon calcitonin
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Université Catholique de Louvain
Glenohumeral Osteoarthritis
Hymovis® Intra-articular Injections vs Corticosteroids Intra-articular Injections in Patients Affected by Glenohumeral Osteoarthritis:
This monocentric randomized open-label study aims to assess the efficacy and safety of a treatment with medium molecular weight hyaluronic acid (HA) compared to a treatment with corticosteroids on patients affected by…
- Trial name
- NCT06043544
- Testing
- Hyaluronic Acid 24 MG in 3 mL Prefilled Syringe, Corticosteroid injection
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Concordia Hospital Rome
Osteoarthritis of the Knee
Safety and Feasibility Study of Mesenchymal Trophic Factor (MTF) for Treatment of Osteoarthritis
Allogeneic mesenchymal trophic factors (MTF) from human umbilical cord tissue-derived mesenchymal stem cells (UC-MSC) injected into the knee joints of 20 patients (group 1) or injected subcutaneously into 20 patients (group 2) is…
- Trial name
- NCT02003131
- Testing
- Trophic factors from umbilical cord mesenchymal stem cells
- Where
- Panama
- Sponsor
- Translational Biosciences
Degenerative Osteoarthritis, Defect of Articular Cartilage
Follow-Up Study of CARTISTEM® Versus Microfracture for the Treatment of Knee Articular Cartilage Injury or Defect
This is a long term follow-up study to investigate the safety and efficacy of CARTISTEM®, human umbilical cord blood-derived mesenchymal stem cells, in repair of cartilage injury or defects, compared with microfracture.
- Trial name
- NCT01626677
- Testing
- CARTISTEM, Microfracture
- Where
- 10 sites in South Korea
- Volunteers
- 103 people
- Sponsor
- Medipost Co Ltd.
Hip Osteoarthritis
Patient Education and Basic Body Awareness Therapy in Hip Osteoarthritis: a Randomized Controlled Trial
The incidence of hip osteoarthritis (OA) is rising in western countries due to an ageing population and the epidemic of obesity.
- Trial name
- HipOA (NCT02884531)
- Testing
- Patient Education and Basic Body Awareness Therapy, Patient Education
- Where
- Norway
- Volunteers
- 101 people
- Sponsor
- University of Bergen
Osteoarthritis, Knee
Use of Perioperative Photograph as a Motivation for Increasing Range of Motion After Primary Total Knee Arthroplasty
Total knee arthroplasty (TKA) is recognized as a successful procedure for treating osteoarthritis (OA) of the knee. One important factor that make the successful surgery is the degree of knee flexion.
- Trial name
- NCT03075319
- Testing
- Received perioperative photograph, Didn't receive perioperative photograph
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Osteoarthritis
A Phase I, Prospective, Randomized, Open-label, Active-Controlled Clinical Trial for Safety Evaluation of Intra-articular Injection of RegenoGel-SP for the Treatment of Moderate to Severe Osteoarthritis
This is a Phase I, prospective, active-controlled, randomized, open-label, clinical trial designed to assess the safety and tolerability of single intra-articular injection of RegenoGel-SP for the treatment of OA.
- Trial name
- NCT02188771
- Testing
- intra-articular administration of RegenoGel-SP or hyaluronic acid (HA)
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- ProCore Ltd.
Knee Osteoarthritis, Knee Pain Chronic
The Effect of Physical Therapy Modalities and Kinesio Taping in Patients With Knee Osteoarthritis
Osteoarthritis (OA) is the most common degenerative joint disease with pathological structural and functional disorders all over the world. 27 million patients diagnosed with osteoarthritis in the USA alone.(1-2)
- Trial name
- NCT05211544
- Testing
- physical therapy modalities and exercise, kinesio taping and exercise, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Abant Izzet Baysal University
Hip Osteoarthritis
Neurocognitive Rehabilitation After Hip Replacement
The purpose of the study is to evaluate the effectiveness of an approach based on neurocognitive rehabilitation exercises in the form of sensory-motor problems, whose solution involves the use of higher cognitive functions…
- Trial name
- NCT02231567
- Testing
- Neurocognitive Rehabilitation, Traditional Rehabilitation
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- University of Roma La Sapienza
Arthropathy of Hip, Hip Osteoarthritis
Comparison of Spinal Anesthesia With Intrathecal Morphine Versus PENG Block With or Without Dexamethasone in Hip Arthroplasty
The goal of this clinical trial is to learn which of three regional anesthesia approaches provides better pain relief and safety for older adults having planned hip replacement surgery.
- Trial name
- THA (NCT07584200)
- Testing
- Intrathecal Morphine, Pericapsular Nerve Group Block, Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Knee, Joint Instability
Combined Prospective and Retrospective Post-Market Follow Up of the 'BPK-S Integration' UC as Primary Implant in the Variant CoCr
Patients who received a total knee endoprosthesis BPK-S Integration between 2011 and 2013 will be invited to participate in this PMCF study provided sufficient source data documentation is available regarding preoperative…
- Trial name
- NCT03406637
- Testing
- BPK-S Integration
- Where
- 2 sites in Belgium
- Volunteers
- 62 people
- Sponsor
- Peter Brehm GmbH
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