Clinical trials: Osteoarthritis Hand
Knee Osteoarthritis (OA)
Functional Hip Strength Improvement in Knee Osteoarthritis Following Single-Dose PRP and a 6-Week Home Exercise Program
This single-group longitudinal study evaluated changes in hip stability isometric strength, knee muscle strength, and activity-related pain in women with knee osteoarthritis following a single-dose intra-articular platelet-rich…
- Trial name
- NCT07307118
- Testing
- Platelet-Rich Plasma (PRP) Injection, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Firat University
Hand Osteoarthritis
Topical Clobetasol Propionate for Inflammatory Hand Osteoarthritis
This is a randomized, double-blind, comparative trial evaluating the efficacy on pain intensity between topical Clobetasol Propionate 0.05% and placebo in patients with symptomatic hand osteoarthritis.
- Trial name
- PROCLAME (NCT07812701)
- Testing
- Propionate de Clobétasol ( 0.05 %)
- Where
- France
- Volunteers
- 187 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis Thumb, Osteoarthritis, Knee
Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints
The study project aims at examining molecular markers in synovial fluid, bone and articular cartilage from osteoarthritic thumb basal joints.
- Conditions
- Osteoarthritis Thumb, Osteoarthritis, Knee, Metabolic Disease
- Trial name
- NCT06370312
- Testing
- Trapeziectomy
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Knee Osteoarthritis
Conventional Instrumentation, Computer Navigation, and Robotic Assistance Techniques in TKA
Knee osteoarthritis is a debilitating disease that can cause severe knee pain and significant limitations to patients' activities of daily living.
- Trial name
- NCT05629715
- Testing
- ROSA Knee System, KneeAlign Computer Assisted Navigation System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Osteoarthritis
Safety and Biologic Activity Study of Gevokizumab to Treat Erosive Osteoarthritis of the Hand
The purpose of this proof-of-concept study is to determine whether gevokizumab is effective in the treatment of inflammatory erosive osteoarthritis of the hand.
- Trial name
- NCT01882491
- Testing
- gevokizumab
- Where
- 23 sites in United States
- Volunteers
- 91 people
- Sponsor
- XOMA (US) LLC
Hand Osteoarthritis, Erosive Osteoarthritis
Methotrexate in Erosive Inflammatory Hand Osteoarthritis
A placebo-controlled randomized controlled trial exploring the effect of methotrexate on pain, function and structural outcomes in erosive inflammatory hand osteoarthritis.
- Trial name
- MERINO (NCT04579848)
- Testing
- Methotrexate Tablets, Folic Acid 1 MG
- Where
- Norway
- Volunteers
- 163 people
- Sponsor
- Diakonhjemmet Hospital
Low Level Laser Therapy, Osteoarthritis
Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.
This study is a randomized, control trial of Active Duty and DoD Beneficiaries, age 18 years or older, with complaints of hand osteoarthritis. Subjects will be randomized into one of two groups receiving either LLLT or sham LLLT.
- Conditions
- Low Level Laser Therapy, Osteoarthritis, Family Medicine, Pain Management
- Trial name
- NCT04692597
- Testing
- Phoenix Thera-Lase System
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- David Moss
Arthritis, Arthritis/Arthrosis
Combining Virtual Reality and Hypnosis to Alleviate Chronic Pain in Elderly Patients with Hand Arthritis
The goal of this pilot randomized clinical trial is to test the efficacy of an intervention combining virtual reality and hypnosis on decreasing pain and improving quality of life in elderly patients with hand arthritis.
- Conditions
- Arthritis, Arthritis/Arthrosis, Arthritis, Rheumatoid, Elderly
- Trial name
- VRHArthrisis (NCT06833905)
- Testing
- Virtual reality: Beach, Virtual Reality: Forest, Hypnosis: Magic Hand
- Volunteers
- 80 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Hand Osteoarthritis
Water-filtered Infrared-A Radiation in Patients With Hand Osteoarthritis
The aim of this clinical trial is to evaluate the effects of water-filtered Infrared-A radiation on patients suffering from hand osteoarthritis.
- Trial name
- NCT06329219
- Testing
- water-filtered Infrared-A radiation
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Osteoarthritis, Hand Osteoarthritis
Balneotherapy and Peloid Therapy Impact Small Joint Diseases
This clinical trial investigates the effects of natural healing factors (mineral water and mud procedures) in combination with regular rehabilitation of patients with degenerative small joint disease.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Foot Osteoarthritis
- Trial name
- NCT06477393
- Testing
- Regular rehababilitation, Heat procedures, Healing mud application
- Where
- 2 sites in Lithuania
- Volunteers
- 130 people
- Sponsor
- Lithuanian University of Health Sciences
Rhizarthrosis
Dual Mobility Total Joint Prosthesis (Touch) for Thumb Carpometacarpal Joint Osteoarthritis
The dual mobility concept currently represents the newest generation of thumb carpometacarpal prostheses. The aim of this study was to evaluate the outcomes of TOUCH® prosthesis.
- Trial name
- NCT05047744
- Testing
- Touch Dual Mobility CMC I Prosthesis
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Kepler University Hospital
Osteoarthritis
Study of the Use of Laser Light to Treat Osteoarthritis of the Hand.
The purpose of this study is to determine whether low level light therapy is effective in the treatment of osteoarthritis of the hand, when the treatment is applied to the hand by an individual in his or her own home.
- Trial name
- NCT00254111
- Testing
- Ultra Probe Laser System
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- TriTech Manufacturing
Hands Osteoarthritis
Corticosteroid Intra-articular Injection in Hands Osteoarthritis
Objective - to evaluate the effectiveness and tolerance of intra-articular injections (IAI) of hexacetonide triamcinolone (HT) for the treatment of osteoarthritis (OA) in interphalangeal joints.
- Trial name
- NCT02102620
- Testing
- Intra-articular injection with corticosteroid, Intra-articular injection with lidocaine
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Osteoarthritis
Subject Insights to Understand the Hand Osteoarthritis (HOA)
Osteoarthritis (OA) is a degenerative joint disease which causes joints to become painful and stiff. HOA is the second most common form of OA and is characterized by stiffness, joint pain and inflammation and tenderness in the…
- Trial name
- NCT03271203
- Testing
- Michigan Hand Outcomes Questionnaire, Real-time data capture app
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- GlaxoSmithKline
Hand Osteoarthritis
Can we Use Estrogen-containing Therapy to Improve Pain in Women After Menopause With Hand Osteoarthritis?
Post-menopausal women aged 40-65 with symptomatic hand osteoarthritis are invited to take part in this feasibility study. The study's aim is to investigate whether it is acceptable to women with painful hand OA to take an…
- Trial name
- HOPE-e (NCT04036929)
- Testing
- Estrogen-bazedoxifene
- Where
- 3 sites in United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Oxford
Osteoarthritis of the Hand
Compassionate Use of Pennsaid Topical Lotion (Diclofenac) in Osteo or Rheumatoid Arthritis
This was a compassionate use, open treatment safety study of Pennsaid topical lotion (diclofenac) for osteo or rheumatoid arthritis.
- Trial name
- NCT01579890
- Testing
- Diclofenac
- Sponsor
- Mallinckrodt
CBD, Hand Osteoarthritis
Is Topical CBD Effective in Treating Thumb Joint Arthritis
Rationale: CBD is commonly being used as an over-the-counter treatment for arthritis-related pain, however no clinical trial has been performed to establish efficacy.
- Trial name
- NCT04611347
- Testing
- CBD, Shea Butter
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Hand Osteoarthritis
An Integrated Self Management Programme to Improve Outcomes in Patients With Hand Osteoarthritis
The goal of this trial is to evaluate the efficacy of an integrated self-management programme in improving clinical outcomes in patients with hand osteoarthritis (OA).
- Trial name
- OASIS-H (NCT06264908)
- Testing
- Integrated self-management programme
- Volunteers
- 90 people
- Sponsor
- Dr Iris Tang Yan Ki
Osteoarthritis Both Hands
Task Shifting in the Care for Patients With Hand Osteoarthritis
The main aim in this randomized controlled trial is to improve access to safe and effective care, professional practice and cost-effective utilisation of health care resources by testing if occupational therapist-led care is as…
- Trial name
- NCT03102788
- Testing
- Rheumatologist-led care., Occupational therapist-led care.
- Where
- 3 sites in Norway
- Volunteers
- 400 people
- Sponsor
- National Resource Center for Rehabilitation in Rheumatology
Osteoarthritis Hand
Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of STT Osteoarthritis
The aim of this open, prospective, multicenter trial is to evaluate the use of a sterile, devitalized, processed umbilical cord amniotic membrane implant placed in joint interposition in the treatment of STT osteoarthritis.
- Trial name
- NCT06038331
- Testing
- SclerFIX-IP
- Where
- 4 sites in France
- Volunteers
- 14 people
- Sponsor
- TBF Genie Tissulaire