Clinical trials: Osteoarthritis Hip
Coxarthrosis
10 Year Clinical Evaluation of Primoris Hip Component
Using the traditional and hitherto used uncemented hip prostheses achieved good clinical results, but one of the drawbacks is the risk of fracture in the femoral shaft in indbankning of the prosthesis (1-2%).
- Trial name
- Primoris (NCT01326832)
- Testing
- Primoris
- Where
- 2 sites in Denmark
- Volunteers
- 350 people
- Sponsor
- Zimmer Biomet
Osteoarthrosis
Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients
The study evaluates the pathophysiological effects of a single dose Methylprednisolone administered prior to total hip-arthroplasty (THA) surgery.
- Trial name
- NCT02445898
- Testing
- Methylprednisolone, Isotonic Sodium Chloride
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis, Knee, Osteoarthritis, Hip
A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip
The primary objective of the study is to evaluate the efficacy of fasinumab compared with placebo, when administered for up to 16 weeks in patients with pain due to osteoarthritis (OA) of the knee or hip.
- Trial name
- FACT OA1 (NCT03161093)
- Testing
- Fasinumab, Naproxen
- Where
- 139 sites in United States, Denmark and 10 more
- Volunteers
- 3,307 people
- Sponsor
- Regeneron Pharmaceuticals
Osteo Arthritis of Hip
Effects of Modified Clamshell Exercises in Patients With Hip Osteoarthritis Grade Ⅱ.
This study focuses on patients diagnosed with Grade II hip osteoarthritis, a degenerative joint condition characterized by pain, reduced range of motion, muscle weakness, and functional limitations.
- Trial name
- NCT07401719
- Testing
- Modified clamshell exercise, Clamshell Exercises, Conventional exercises
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Osteoarthritis, Hip, Joint Deformities, Acquired
Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty
The purpose of this study is to establish whether or not there is a clinical advantage to the use of Aquamantys® System from Medtronic Advanced Energy (formerly Salient Surgical Technologies) in patients undergoing primary total…
- Conditions
- Osteoarthritis, Hip, Joint Deformities, Acquired, Hip Dislocation, Congenital, Osteonecrosis
- Trial name
- Aquamantys (NCT01583465)
- Testing
- Aquamantys, standard electrocautery (Bovie)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Joint Implant Surgeons, Inc.
Coxarthrosis
Efficacy and Safety of Ostenil® Plus in the Treatment of Coxarthrosis
PMCF study to observe the Routine application of Ostenil® Plus in the Treatment of pain and restricted mobility in degenerative and traumatic changes of the Hip Joint.
- Trial name
- NCT03809962
- Testing
- Ostenil® Plus
- Where
- 7 sites in Germany
- Volunteers
- 170 people
- Sponsor
- TRB Chemedica AG
Total Hip Replacement, Coxarthrosis
Comparison of the Use of Conventional Ancillary Reaming and Single-use Ancillary Reaming Material in Total Hip Replacement
The main objective of the study is to compare the use of single-use ancillary reaming material during total hip replacement and conventional reusable ancillary reaming material.
- Trial name
- LUUC (NCT04903860)
- Testing
- total hip replacement with single use ancillary, total hip replacement with conventional ancillary
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Total Hip Arthroplasty, Osteoarthritis, Hip
Migration in Total Hip Arthroplasty with a Cemented BiMobile Cup: Better Stability with More Cement?
Objective: The main objective of this study is to compare the (early) migration of the cemented BiMobile cup at two year post-surgery between two different cup sizes after standard optimal reaming, and consequently adjusting the…
- Trial name
- Be-Mobile (NCT04049279)
- Testing
- BiMobile standard cement, BiMobile larger cement, Avantage standard cement
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- JointResearch
Hip Osteoarthritis, Joint Diseases
Robotic Total Hip Arthroplasty Anesthesia Management
Robotic arthroplasty is increasing in acceptance on a global scale as a result of advancements in orthopedic surgery technology.
- Conditions
- Hip Osteoarthritis, Joint Diseases, Anesthesia
- Trial name
- NCT05794282
- Testing
- the robot assisted total hip arthroplasty, the conventional total hip arthroplasty
- Volunteers
- 150 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Osteoarthritis
A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis (0686-006)
This study is being conducted to assess the safety and tolerability of MK-0686 and to evaluate its efficacy in the treatment of osteoarthritis of the hip or knee in men and women.
- Trial name
- NCT00296569
- Testing
- MK0686
- Volunteers
- 150 people
- Sponsor
- Merck Sharp & Dohme LLC
Hip Osteoarthritis
Mirogabalin for Total Hip Arthroplasty
The purpose of this study is to confirm the analgesic effect of mirogabalin in patients undergoing unilateral hip arthroplasty.
- Trial name
- NCT05938088
- Testing
- Arm I (mirogabalin group)
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Gangnam Severance Hospital
Osteoarthritis, Hip
H-29 DELTA Multihole TT Study.
This study is aimed to provide a clinical and radiographic evaluation of 50 suitable subjects who underwent a complex primary or a revision Total Hip Arthroplasties with DELTA Multihole TT acetabular cup in 2019 onwards.
- Trial name
- NCT05007067
- Testing
- DELTA Multihole TT
- Where
- Poland
- Volunteers
- 7 people
- Sponsor
- Limacorporate S.p.a
Hip Fracture, Arthrosis
Preventing Loss of Weight, Fat Free Mass and Activities of Daily Living
Malnutrition of elder orthopaedic patients leads to weight loss and loss of fat free mass. Changes in the individual's nutritional status and body composition may adversely affect the patient's postoperative level of activity.
- Trial name
- NCT00373971
- Testing
- Involving the patients in their own nutritional care
- Where
- Denmark
- Volunteers
- 252 people
- Sponsor
- University of Aarhus
Osteoarthritis, Avascular Necrosis
Trinity™ BIOLOX Delta™ CoC THR Multi-center Study
To demonstrate the safety and effectiveness of the Trinity™ BIOLOX delta™ Ceramic-on-Ceramic Total Hip System in comparison to the Trinity™ Acetabular Hip System,which is FDA cleared for use in the U.S.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, CDH
- Trial name
- NCT01921309
- Testing
- Trinity CoC Total Hip System, Trinity Ceramic-on-Poly THR
- Where
- 10 sites in United States, United Kingdom
- Volunteers
- 342 people
- Sponsor
- Corin
Osteoarthritis, Hip, Hip Pain Chronic
The Effect of Dexamethasone Administration Route on Pain and Inflammatory Response in PENG Block for Total Hip Arthroplasty
This study aims to evaluate the effect of the dexamethasone administration route (intravenous vs. perineural) on postoperative pain, inflammatory response, and clinical outcomes in patients undergoing total hip arthroplasty (THA)…
- Conditions
- Osteoarthritis, Hip, Hip Pain Chronic, Hip Arthropathy, Hip Arthritis
- Trial name
- NCT06789328
- Testing
- perineural Dexamethasone 4mg, intravenous Dexamethsone 4mg
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Osteo Arthritis Knee, Osteoarthritis, Knee
OA Optimization Program Pilot Trial
Total joint replacement is a highly successful treatment option for people affected by severe osteoarthritis (OA), however, the mismatch between resources and demand for this surgery means that many patients face long wait times…
- Conditions
- Osteo Arthritis Knee, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis
- Trial name
- NCT05389371
- Testing
- Alberta Healthy Living Program, Alberta Obesity Centre Program, Osteoarthritis advice
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Calgary
Osteoarthritis of the Hip
Comparison of MIS Anterior Versus MIS Anterolateral Approach
Aim of the present investigation is to analyse the amount of muscle trauma in relation to the surgical approach and to the individual postoperative functional recovery.
- Trial name
- NCT02458144
- Testing
- Total hip arthroplasty
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Osteoarthritis, Knee, Osteoarthritis, Hip
A Long Term Study of the Safety of Tanezumab When Administered By Subcutaneous Injections
This study will investigate the safety of three fixed dose levels of tanezumab (2.5 mg, 5 mg, and 10 mg) administered at an 8-week interval by subcutaneous injection multiple (7) times during the study treatment period.
- Trial name
- NCT00994890
- Testing
- Tanezumab 2.5 mg, Tanezumab 5 mg, Tanezumab 10 mg
- Where
- 100 sites in United States
- Volunteers
- 679 people
- Sponsor
- Pfizer
Degenerative Joint Disease, Osteoarthritis
Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA)
You are being asked to take part in this research study because you are scheduled to have total hip replacement (arthroplasty) surgery.
- Trial name
- NCT01391182
- Testing
- EACA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoarthritis, Rheumatoid Arthritis
A Randomised Trial Comparing Anterior Versus Posterior Approach in Total Hip Replacement
This is a single-centre, randomised, prospective clinical follow-up study to evaluate clinical outcome and gait analysis after total hip arthroplasty using the standard postero-lateral approach or the minimally invasive anterior…
- Trial name
- NCT01106560
- Testing
- Minimally Invasive Anterior Approach, Standard postero-lateral approach
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Medacta International SA
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