Clinical trials: Osteoarthritis Pain
Peripheral Neuropathy, Osteoarthritis
A Study to Investigate the Genetic Variation of Dopamine Pathway in Patients With Chronic Pain
Patients having completed former trials T1001-01 or T1001-02 will undergo one blood sampling for genotyping purposes. In addition they will compete the personality questionnaires they had completed in the former trial.
- Trial name
- NCT02989792
- Testing
- Blood sampling for genotyping, Personality Questionnaires completion
- Where
- 4 sites in Belgium, France
- Volunteers
- 110 people
- Sponsor
- Tools4Patient
Osteoarthritis
The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty
The purpose of this study is to use a new combination of anesthesia techniques in an attempt to minimize early pain after surgery and improve the patient's ability to participate more fully with physical therapy.
- Trial name
- NCT00620828
- Testing
- Ropivicaine 0.5%
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Duke University
Hip Arthropathy, Hip Osteoarthritis
Erector Spinae vs. PENG Block for Total Hip Arthroplasty
Effect of PENG block and ESPB on pain management, and NLR and PLR following knee arthroplasty
- Conditions
- Hip Arthropathy, Hip Osteoarthritis, Hip Pain Chronic
- Trial name
- NCT06083428
- Testing
- Ropivacaine 0.2% Injectable Solution Erector Spinae Plane Block, Ropivacaine 0.2% Injectable Solution - PENG block, Control Test
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis
Study of the Use of Laser Light to Treat Osteoarthritis of the Hand.
The purpose of this study is to determine whether low level light therapy is effective in the treatment of osteoarthritis of the hand, when the treatment is applied to the hand by an individual in his or her own home.
- Trial name
- NCT00254111
- Testing
- Ultra Probe Laser System
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- TriTech Manufacturing
Degenerative Joint Disease of Shoulder
Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After Receiving a Reverse Total Shoulder Arthroplasty (RTSA)
The main purpose of this research is to find out if a treatment called cryoneurolysis can reduce pain after reverse total shoulder replacement surgery. This treatment uses cold to temporarily block a nerve in the shoulder.
- Trial name
- NCT07125833
- Testing
- Cryoneurolysis, No cryoneurolysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- North Texas Medical Research Institute, PLLC
Osteoarthritis, Pain
Effectiveness of Tailored Activity Pacing for Symptomatic Osteoarthritis
The primary objective of this project is to examine effectiveness of a tailored pacing intervention on fatigue, pain, and physical function compared to general pacing intervention and usual care groups.
- Trial name
- AIM (NCT01192516)
- Testing
- Tailored Activity Pacing, General Activity Pacing
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- US Department of Veterans Affairs
Osteoarthritis Knee Pain
Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain
A Randomized, Double-Blind, Placebo-Controlled, Single Dose Study to Assess the Safety and Efficacy of SL1002 for the Treatment of Knee Pain in Patients with Osteoarthritis of the Knee.
- Trial name
- NCT07226258
- Testing
- SL1002, Normal Saline
- Where
- 22 sites in United States
- Volunteers
- 150 people
- Sponsor
- Saol Therapeutics Inc
Pain, Osteoarthritis, Knee
Audio-Recorded vs. Nurse-Led Brief Mindfulness-Based Intervention
This is a single-site, three-arm, parallel-group randomized clinical trial (RCT). The clinical effects of a nurse-led, very brief, preoperative mindfulness-based intervention for hip and knee replacement patients will be…
- Conditions
- Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT05054595
- Testing
- Standard Pain Management, Audio-Recorded Mindfulness-Based Intervention, Nurse-Led Mindfulness-Based Intervention
- Sponsor
- University of Utah
Knee Osteoarthritis (Knee OA)
High-Intensity Laser Therapy (HILT) in Patients With Knee Osteoarthritis
This randomized placebo-controlled trial aims to evaluate the effectiveness of High-Intensity Laser Therapy (HILT) as an adjunct to standard outpatient physiotherapy in patients with knee osteoarthritis.
- Trial name
- NCT07661407
- Testing
- Conventional Physiotherapy, High-Intensity Laser Therapy (HILT)
- Volunteers
- 72 people
- Sponsor
- University of Rzeszow
Osteoarthritis (OA) of the Knee
INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE
The goal of this clinical trial is to evaluate the effectiveness of Neural Ice for pain management associated with knee osteoarthritis in adults aged 22-80 years.
- Trial name
- ICE (NCT06700109)
- Testing
- Neural Ice, Triamcinolone acetate
- Where
- 15 sites in United States
- Volunteers
- 263 people
- Sponsor
- Brixton Biosciences, Inc.
Osteoarthritis
A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 In Participants With Osteoarthritis Pain
The main purpose of this study is to evaluate the efficacy and safety of LY3857210 in participants with Osteoarthritic Pain. This trial is part of the chronic pain master protocol, H0P-MC-CPMP (NCT05986292), which is a protocol…
- Trial name
- OA05 (NCT05620563)
- Testing
- LY3857210
- Where
- 30 sites in United States, Puerto Rico
- Volunteers
- 147 people
- Sponsor
- Eli Lilly and Company
Osteoarthritis of the Knee, Degenerative Osteoarthritis
Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis
The primary research purpose is to determine if the use of a drug therapy intervention (each study participant will be randomly assigned to receive one of 3 study medications which will be blinded from everyone, including the…
- Conditions
- Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
- Trial name
- PRPNSAIDsKOA (NCT05742763)
- Testing
- Ibuprofen and PRP, Acetaminophen and PRP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- QC Kinetix LLC
Knee Osteoarthritis
Estimation of the Localization Accuracy of the Genicular Ablation Procedure Applied for Chronic Pain Suppression
Estimation of the localization accuracy of the genicular ablation procedure applied for chronic pain suppression
- Trial name
- NCT02873611
- Testing
- MRI, genicular ablation procedure
- Volunteers
- 30 people
- Sponsor
- TPM Medical Systems Ltd.
Hip Osteoarthritis, Total Hip Arthroplasty
Clinical Phenotypes in Persons With Hip Osteoarthritis and Prognostic Factors for Outcome After Total Hip Arthroplasty
This prospective longitudinal cohort study aims (1) to identify clinical phenotypes in persons with hip osteoarthritis and after total hip arthroplasty, and (2) to identify prognostic factors for outcomes after total hip…
- Trial name
- HIPPROCLIPS (NCT05265858)
- Testing
- Total Hip Arthroplasty
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
Knee Osteoarthritis
Decompression Versus Heat and Decompression in Knee OA
a randomized controlled trial tends to compare the effects of adding superficial heating during the application of knee decompression session to the results of decompression alone without heating.
- Trial name
- NCT06428071
- Testing
- standard physical therapy, knee Decompression, hot pack
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- University of Hail
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Myofascial Trigger Point Pain, Knee Osteoarthritis
Effect of High Intensity Laser in Treatment of Myofascial Trigger Points in Symptomatic Knee Osteoarthritis
This study was conducted to investigate the effect of High intensity laser therapy( HILT) on pressure pain threshold, serum cortisol level, passive knee range of motion, and changes of functional disability in patients with…
- Trial name
- NCT05148416
- Testing
- High intensity laser treatment, knee osteoarthritis conventional exercises program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Osteoarthritis, Knee
Effects of Strength Training on Knee Osteoarthritis
To understand the effects of leg strengthening exercise, we will study the effects of strength training of the legs in four groups of people: (1) osteoarthritis (OA) with knee pain; (2) OA without knee pain; (3) no OA but elderly…
- Trial name
- NCT00000406
- Testing
- Progressive resistance exercise
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Indiana University
Degenerative Joint Disease
Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty
To compare two methods of post-operative pain management in patients undergoing total hip arthroplasty. There is a perception that the periarticular injections may not be as effective in controlling post-operative pain.
- Trial name
- DA THA pain (NCT02904993)
- Testing
- L2 paravertebral block, periarticular injection group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteo Arthritis Knee
Evaluation of the Effect of Different Doses of Ozone Therapy on Pain and Function of Patients With Knee Osteoarthritis
This study is designed as a randomized clinical trial that will be conducted in Hazrat Rasool Akram Hospital in Tehran. Patients with knee osteoarthritis were selected based on the study entry criteria and written consent was…
- Trial name
- NCT06088706
- Testing
- Intra-articular injection of ozone
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Ahmad Nazari
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