Clinical trials: Osteoarthritis Pain
Thumb Osteoarthritis
Magnesium as an Adjunct for Pain Treatment After Surgery for Thumb Base Arthrosis
A randomised controlled trial of addition to the standard pain treatment of 1000 mg oral magnesium citrate or placebo for 7 Days during surgery for thumb base arthrosis.
- Trial name
- NCT04613154
- Testing
- magnesiumcitrate
- Where
- Sweden
- Volunteers
- 9 people
- Sponsor
- Region Örebro County
Osteoarthritis, Knee
Pain Neuroscience Education in Patients With Total Knee Arthroplasty
The aim of Pain Neuroscience Education (PNE) is to explain to patients the biological and physiological processes involved in a pain experience and, more importantly, defocus the issues associated with the anatomical structures.
- Trial name
- NCT05928351
- Testing
- Pain Neuroscience Education, Standard Physiotherapy Program (SPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Severe Osteoarthritis of the Knee
Open Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the Knee
This Open Label Extension (OLE) study will assess the safety of long-term treatment with a 4 mL intra-articular injection of Ampion™ in adults with pain due to severe osteoarthritis of the knee
- Trial name
- NCT03349645
- Testing
- 4 mL injection of AMPION™
- Where
- 11 sites in United States
- Volunteers
- 94 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Knee Osteoarthristis
Ultrasound Duration Effects on Knee Osteoarthritis Pain and Function
This study aims to compare the effects of different ultrasound treatment durations on pain and physical function in patients with knee osteoarthritis.
- Trial name
- NCT07057869
- Testing
- 5-minute Ultrasound Group, 10-minute Ultrasound Group, 15-minute Ultrasound Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- KTO Karatay University
Hand Osteoarthritis
Hand Osteoarthritis: Investigating Pain Trajectories and Association With Biomarkers Including Estrogen Cohort
Adults with painful hand osteoarthritis are invited to take part in this observational cohort study. The course of hand pain can vary and is not well understood - some people seem to have short episodes of worsening pain…
- Trial name
- HOPE-c (NCT05105854)
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Oxford
Osteoarthitis
Clinical Trial to Assess the Safety and Efficacy of Intra-articular Injection Collagen Versus Hyaluronic Acid on Knee Osteoarthritis
This study was designed to assess the efficacy for pain relief, functional improvement, and safety of intra-articular collagen injections compared to hyaluronic acid injections for knee osteoarthritis.
- Trial name
- NCT07511777
- Testing
- CartiZol, Synovian inj.
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Cellontech Co., Ltd.
Osteo Arthritis Knee
Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms
This clinical trial aims to evaluate whether a 2 week regimen of transcranial direct current stimulation (tDCS) paired with mindfulness-based meditation (MBM) can improve pain modulation, reduce clinical pain, and alleviate…
- Trial name
- NCT04375072
- Testing
- active tDCS paired with active MBM
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Arizona
Osteoarthritis, Knee
Effect of Low Intensity Training Combined With Partial Restriction of Blood Flow in Individuals With Knee Osteoarthritis
Osteoarthritis (OA) is a chronic degenerative infection that presents clinical features such as pain and limited range of motion.
- Trial name
- NCT04819672
- Testing
- Low Intensity Training associated with Partial Blood Flow
- Volunteers
- 66 people
- Sponsor
- Universidade Federal do Ceara
Osteoarthritis
Evaluation of the Latella™ Knee Implant System for Medial Osteoarthritis Pain Reduction
The objective of the Latella-US study is to demonstrate the safety and efficacy of the Latella Knee Implant System for the reduction of medial osteoarthritis pain.
- Trial name
- Latella-US (NCT02608957)
- Testing
- Latella Knee Implant System
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Cotera, Inc.
Osteoarthritis
Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuroendocrine Function in Men
This study will examine the effects of morphine on leuteinizing hormone, testosterone, adrenocorticotropic hormone and cortisol in men.
- Trial name
- NCT00088296
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Osteoarthritis, Knee
Study of Pain Catastrophizing-2 (SPAC-2)
This study experimentally manipulates pain catastrophizing in order to investigate the neural mechanisms by which pain catastrophizing influences the experience of pain in different ethnic groups among adults with knee…
- Trial name
- SPAC (NCT04805190)
- Testing
- Cognitive-Behavioral Intervention, Pain Education
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Florida
Osteoarthritis of the Shoulder, Adhesive Capsulitis
Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Adhesive Capsulitis
This is a double-blind study to evaluate the efficacy and safety of FX006 in patients with glenohumeral osteoarthritis (OA) or shoulder adhesive capsulitis (AC).
- Trial name
- NCT04160091
- Testing
- FX006, Normal Saline
- Where
- 27 sites in United States
- Volunteers
- 19 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis
A Placebo Controlled, Double Blind, Randomised, 8-week Phase IIa Proof of Concept Study to Assess the Efficacy and Safety of AKR 202 in Patients With Osteoarthritis Pain
This proof of concept study will be a placebo controlled, randomised, double blind, parallel study. The purpose of the study is to determine efficacy for AKR 202 in the treatment of osteoarthritis (OA) pain in the knee.
- Trial name
- NCT02003118
- Testing
- AKR 202
- Where
- Austria
- Volunteers
- 266 people
- Sponsor
- Akron Molecules AG
Osteoarthritis, Rheumatoid Arthritis
Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder
The aim of this study is to find out how patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis receiving NSAID-therapy are treated and managed by their doctor in usual clinical practice, how patients…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- EVIDENCE (NCT01176682)
- Where
- 244 sites in Belgium, France and 10 more
- Volunteers
- 1,149 people
- Sponsor
- AstraZeneca
Knee Osteoarthritis, Central Sensitisation
Relationship Between Central Sensitization and Kinesiophobia in Knee Osteoarthritis
Objective: The knee joint is one of most common locations in OA. In recent years, it has been accepted that there are different pain phenotypes and patient subgroups in knee OA and that central sensitization (CS) mechanisms are…
- Conditions
- Knee Osteoarthritis, Central Sensitisation, Kinesiophobia
- Trial name
- NCT06336278
- Testing
- Pressure Algometer
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Selda Sarıkaya
Osteoarthritis
Efficacy and Safety of ATB-346 Versus Placebo in Osteoarthritis Patients
The primary objective of this study is to evaluate the efficacy of a 14-day dosing regimen of ATB-346 at doses of 150 mg, 200 mg and 250 mg compared to placebo in reducing osteoarthritis knee pain as measured by changes in the…
- Trial name
- NCT03978208
- Testing
- ATB-346 low dose, ATB-346 mid-dose, ATB-346 standard dose
- Where
- 35 sites in Canada
- Volunteers
- 381 people
- Sponsor
- Antibe Therapeutics Inc.
Post-operative Pain, Total Shoulder Arthroplasty
LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs
This will be a single-center, prospective, randomized controlled cross-sectional study comparing interscalene brachial plexus block with liposomal bupivacaine versus bupivacaine with epinephrine and PF dexamethasone in patients…
- Conditions
- Post-operative Pain, Total Shoulder Arthroplasty, Osteoarthritis of the Shoulder, Pain Management
- Trial name
- NCT03887650
- Testing
- Liposomal Bupivicaine 1.3%, Bupivacaine 0.5%
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Hartford Hospital
Osteoarthritis
Effectiveness of a Training Program in Improving Coping Skills in People With Arthritis Pain
Osteoarthritis (OA) is the leading cause of disability in the United States. Studies have shown that training patients to cope with pain improves physical and social functioning, increases self-efficacy, and reduces psychological…
- Trial name
- NCT00636454
- Testing
- Coping skills training (CST) for chronic pain, Usual care
- Where
- 3 sites in United States
- Volunteers
- 257 people
- Sponsor
- Stony Brook University
Osteoarthritis
Comparison of Anesthetic Techniques on Total Hip Arthroplasty
To compare analgesia and orthopedic rehabilitation milestones in patients receiving either spinal anesthesia (local anesthetic plus opioid) or general endotracheal anesthesia with lumbar plexus block.
- Trial name
- NCT01359865
- Testing
- Lumbar Plexus Block
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Osteoarthritis, Pain
Celebrex Total Knee Arthroplasty Study
This study will investigate the benefits of administering celecoxib (Celebrex), a selective cyclooxygenase -2 (COX-2) inhibitor, in treating osteoarthritis (OA) subjects undergoing elective unilateral primary total knee…
- Trial name
- NCT00359151
- Testing
- Celecoxib
- Where
- 7 sites in United States
- Volunteers
- 22 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
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