Clinical trials: Osteoarthritis Pain
Osteoarthritis of the Knee
A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee
The primary purpose of the study is to evaluate the change from baseline after 4 weeks of topical administration of TV-45070 (4% and 8% ointment) compared with placebo for the relief of symptoms of primary OA affecting a single…
- Trial name
- NCT02068599
- Testing
- TV-45070
- Where
- 42 sites in United States
- Volunteers
- 389 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Hip Osteoarthritis
Comparison of the Effect of Intra Articular Steroid Injection and Pericapsular Nerve Group Block for Hip Osteoarthritis
The most common cause of hip joint dysfunction in the elderly is degenerative osteoarthritis of the hip. Innervation of the hip joint capsule is provided by the obturator nerve, the accessory obturator nerve, and the femoral…
- Trial name
- NCT05136248
- Testing
- intraarticular injection, peng block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Osteoarthritis, Knee, Osteoarthritis Knees Both
Astaxanthin for Management of Inflammation in Knee Osteoarthritis
Over 30 million Americans are currently affected by osteoarthritis (OA), with prevalence expected to increase 40% by 2025 as a result of the aging population and obesity epidemic.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis Knees Both, Joint Inflammation
- Trial name
- NCT05138549
- Testing
- Astaxanthin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Prisma Health-Midlands
Osteoarthritis, Knee
Effects of Neurodynamics of Pain and Function in Patients With Knee Osteoarthrosis
Osteoarthritis is defined as a degenerative joint disease characterised by a decrease in joint space due to cartilage loss and the presence of subchondral sclerosis and osteophytes.
- Trial name
- NCT05375448
- Testing
- Neural mobilisation
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- CEU San Pablo University
Osteoarthritis
Efficacy Test of Curcuminoid Standardized Turmeric Capsules to Improving Inflammatory Biomarkers in Osteoarthritis Genu
The goal of this clinical trial is to learn if Curcuminoid Standardized Turmeric Capsules works to treat Osteoarthritis Genu in adults. It will also learn about the safety of Curcuminoid Standardized Turmeric Capsules.
- Trial name
- ETCS (NCT07183215)
- Testing
- Curcuminoid Standardized Turmeric Capsules
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Gadjah Mada University
Osteoarthritis, Knee
Investigating the Effect of Deep Sea Krill Oil Supplementation in Osteoarthritis of the Knee
To evaluate the effectiveness of 4 g Swisse High Strength Deep Sea Krill Oil (Superba BOOST) daily on pain reduction in adults with mild to moderate osteoarthritis of the knee compared to placebo over a 6 month period.
- Trial name
- NCT03483090
- Testing
- Swisse High Strength Deep Sea Krill Oil
- Where
- 4 sites in Australia
- Volunteers
- 235 people
- Sponsor
- Swisse Wellness Pty Ltd
Knee Osteoarthritis
Efficacy of Celecoxib vs Placebo to Prevent Pain in a Paced Walk
A paced 20-minute walk is a reproducible model for acute pain in knee osteoarthritis
- Trial name
- NCT00194090
- Testing
- celecoxib
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University Hospitals Cleveland Medical Center
Osteoarthritis (OA) of the Knee, Knee Pain Arthritis
Imageless Navigation Versus Image-Based Navigation in Robotic-Assisted Total Knee Arthroplasty for Knee Osteoarthritis
The goal of this clinical trial is to learn if imageless navigation is not inferior to image-based navigation in robotic-assisted total knee arthroplasty (RA-TKA) for treating patients with knee osteoarthritis.
- Conditions
- Osteoarthritis (OA) of the Knee, Knee Pain Arthritis, Total Knee Arthroplasty (TKA), Robotic Assisted Arthroplasty
- Trial name
- NCT07522489
- Testing
- Imageless Robotic-Assisted Total Knee Arthroplasty, Image-based Robotic-Assisted Total Knee Arthroplasty
- Where
- Poland
- Volunteers
- 146 people
- Sponsor
- Medical University of Warsaw
Osteoarthritis of the Knee
To Compare the Efficacy and Safety of LAYLA in Osteoarthritis Patients
This is a randomized, double-blind study to compare the efficacy and safety of LAYLA tablet and Joins tablet in the treatment of osteoarthritis of the knee.
- Trial name
- NCT01768468
- Testing
- LAYLA tablet, JOINS tablet
- Where
- 6 sites in South Korea
- Volunteers
- 124 people
- Sponsor
- PMG Pharm Co., Ltd
Osteo Arthritis Knee, Pain
Use of a Self-Guided Mindfulness Mobile Application to Improve Pain Outcomes in Individuals With Knee Osteoarthritis
This study will investigate if mindfulness training via a smartphone mobile app is effective in improving OA-related knee pain.
- Trial name
- NCT03936088
- Testing
- Intervention -- "Headspace" mindfulness application, Control -- "My Water Balance" application
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- jilliansylvester
Knee Disease, Knee Deformity
Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery
The ultrasound-guided selective blockade of the saphenous nerve in the adductor canal provides effective analgesia and reduces postoperative pain in patients undergoing arthroscopic medial meniscectomy.
- Conditions
- Knee Disease, Knee Deformity, Knee Pain Chronic, Knee Arthropathy
- Trial name
- NCT06084403
- Testing
- 20 ml volume adductor canal block, 30 ml volume adductor canal block, 40 ml volume adductor canal block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Knee Osteoarthritis
Kinesiophobia, Pain, Functional Status and Self-Efficacy in Patients With Knee Osteoarthritis
Objective: The aim of this study is to examine the relationship between kinesiophobia, pain, functional status and self efficacy in patients with knee osteoarthritis.
- Trial name
- NCT05036551
- Testing
- Kellgren Lawrence classification
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hacettepe University
Knee Arthritis, Knee Osteoarthritis
Gold Factor on Knee Joint Health and Function
The purpose of this clinical study was to determine whether gold nanoparticles (AuNP) supplement holds clinical value in improving joint health, function, and quality of life for arthritis patients.
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic, Knee Discomfort
- Trial name
- NCT05347602
- Testing
- Gold Factor (Gold Nanoparticles, AuNPs)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- 4Life Research, LLC
Knee Osteoarthritis
Investigation of the Effects of Physiotherapy in Patients With Platelet Rich Plasma (PRP) Applied Knee Osteoarthritis
This study evaluates effects of PRP and physiotherapy on pain, physical function and quality of life in patients with knee osteoarthritis.
- Trial name
- NCT04387396
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Hacettepe University
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Effects of Different Relaxation Therapies on Pain and Sleep in Hip and Knee Arthroplasty Patients
Hip and knee replacement surgery is commonly performed in older adults. After surgery, many patients experience pain, limited movement, and sleep problems.
- Trial name
- NCT07354542
- Testing
- Virtual Reality-Based Relaxation, Traditional Relaxation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROCOTYL® C Acetabular Components
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) components marketed in the European Union (EU).
- Trial name
- NCT03576573
- Testing
- PROCOTYL® C
- Where
- Germany
- Volunteers
- 143 people
- Sponsor
- MicroPort Orthopedics Inc.
Osteoarthritis, Hip
MONOVISC for Hip Joint Pain Relief Due to Osteoarthritis
Obtain real world, post market data to confirm the clinical improvement and safety in patients treated with a single injection of MONOVISC for the symptomatic relief of osteoarthritis in the hip joint.
- Trial name
- NCT04204083
- Testing
- Monovisc
- Where
- 4 sites in Czechia, Poland
- Volunteers
- 25 people
- Sponsor
- Anika Therapeutics, Inc.
Osteoarthritis, Knee
Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
This study will evaluate the use of a local injection around the knee (periarticular) during total knee replacement (TKR) surgery to see if it reduces postoperative pain levels.
- Trial name
- NCT02570503
- Testing
- Ropivacaine, Ketorolac, Clonidine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Knee Arthritis Osteoarthritis, Balance Assessment
Popliteus and Quadriceps Muscle Thickness and Clinical Parameters in Knee Osteoarthritis
This study aims to examine the relationships between the ultrasonographic muscle thicknesses of the popliteus and quadriceps muscles and functional capacity, balance, and pain levels in elderly patients with knee osteoarthritis…
- Trial name
- NCT07834827
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Afyonkarahisar Health Sciences University
Analgesia and Anti-inflammatory of Osteoarthritis
A Trial of HRF2105 Patch in Relieving Pain of Osteoarthritis
The study is being conducted to evaluate the efficacy, and safety of HRF2105patch in relieving pain of Osteoarthritis.
- Trial name
- NCT06047483
- Testing
- HRF2105 patch, Loxoprofen patch
- Volunteers
- 90 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
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