Clinical trials: Osteoarthritis Pain
Osteoarthritis
Efficacy of Proprietary Cherry Juice Blend in Osteoarthritis of the Knee
The primary purpose of this research study is to test the ability of a proprietary cherry juice blend to be helpful in the treatment of osteoarthritis (OA) of the knee.
- Trial name
- NCT00443092
- Testing
- proprietary cherry juice blend (food), control juice (kool aid blend)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- CherryPharm
Osteoarthritis
Tanezumab In Osteoarthritis Of The Hip Or Knee
The purpose of the study is to test the efficacy and safety of 2 doses of tanezumab compared to oxycodone CR and placebo in patients with osteoarthritis
- Trial name
- NCT00985621
- Testing
- tanezumab 10 mg, tanezumab 5 mg, oxycodone
- Where
- 112 sites in United States, Austria and 5 more
- Volunteers
- 614 people
- Sponsor
- Pfizer
Osteoarthritis Knees Both, Pain, Chronic
Investigation of the Effectiveness of a Structured Squat-based Program in Knee Osteoarthritis Rehabilitation
The main purpose of the study is to examine the effect of squat-based exercise approach in individuals with knee osteoarthritis.
- Conditions
- Osteoarthritis Knees Both, Pain, Chronic, Walking, Difficulty
- Trial name
- NCT04588558
- Testing
- Flywheel exercise, Home exercise, Electrotherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul Medipol University Hospital
Hip Osteoarthritis, Hip Pain Chronic
Fast Track Total Hip Arthroplasty vs Standard Care
Fast-track total hip arthroplasty (THA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-H (NCT04211987)
- Testing
- fast track care protocol, standard care protocol
- Where
- Italy
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Hip Osteoarthritis, Knee Osteoarthritis
The Effects of Conventional Exercise Combined With Core Stabilization Exercise by Telerehabilitation in Patients With Hip and/or Knee Osteoarthritis
Age-related hip and knee osteoarthritis is the leading cause of pain and locomotor problems worldwide. There is no definitive solution in the treatment of hip and knee osteoarthritis.
- Trial name
- NCT05272748
- Testing
- Conventional Exercise + Core Stabilization Exercise, Conventional Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Saglik Bilimleri Universitesi
Knee Osteoarthritis
Effects Of Maitland's Mobilization At Mid Versus End Range In Knee Osteoarthritis Patients
Knee Osteoarthritis (OA) is the most common form of arthritis affecting mostly elderly people contributing to major cause of disability worldwide.In knee osteoarthritis Maitland's manual therapy technique could be the most…
- Trial name
- NCT06751095
- Testing
- Maitland's Mobilization in End range, Maitland's mobilization in Mid range
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Pain Syndrome, Pain, Chronic
Validity, Reliability and Responsiveness of Pain Sensitization Questionnaire
The aim of this study was to translate the Pain Sensitivity Questionnaire, which was developed to determine the level of pain sensitivity of individuals, to Turkish and to evaluate the validity and reliability of the Turkish…
- Conditions
- Pain Syndrome, Pain, Chronic, Knee Osteoarthritis
- Trial name
- NCT04162730
- Testing
- Pressure pain threshold and behavioural data
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Acibadem University
Chronic Pain, Osteoarthritis, Knee
Embo Registry; National Registry for Artery Embolization
Embo Registry is a retrospective and prospective observational study to evaluate real world effectiveness and the use of Artery Embolization as a treatment for chronic pain with patients that have osteoarthritis and localized…
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder
- Trial name
- NCT06477965
- Testing
- Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions of North Carolina
Osteoarthritis, Knee
Functional Outcome and Analgesia in TKA: Radiofrequency vs Continuous Adductor Canal Block
This randomized, double blind controlled trial is designed to investigate the potential benefits of radiofrequency in terms of analgesia and functional outcome, compared to the conventional continuous adductor canal block, for…
- Trial name
- NCT02680392
- Testing
- Pulsed and Continuous Radiofrequency, Continuous Adductor Canal Block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Hyaluronate, Osteoarthritis
Efficacy of Three Weekly Injections of a Bacterial-- Sourced Hyaluronate on Pain and Function in Patients With Knee Osteoarthritis (OA)
Three weekly injections of hyaluronate (Hya-Joint) are safe and well tolerated, provide rapid pain relief as early as 1 and 2 weeks after the first injection, and improve function in patients with knee osteoarthritis.
- Conditions
- Hyaluronate, Osteoarthritis, Knee
- Trial name
- NCT01185444
- Testing
- Hya-Joint, Hyalgan
- Where
- Taiwan
- Volunteers
- 89 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Pain, Low Back Pain
Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain
The purpose of this study is to determine whether BEMA Buprenorphine is safe in the treatment of chronic pain.
- Conditions
- Pain, Low Back Pain, Osteoarthritis, Neuropathic Pain
- Trial name
- NCT01298765
- Testing
- BEMA Buprenorphine
- Where
- 26 sites in United States
- Volunteers
- 302 people
- Sponsor
- BioDelivery Sciences International
Osteoarthritis, Knee
A Controlled Study of an Herbal Topical Patch in Treating Osteoarthritis (OA) of the Knee
An evaluation of the safety and efficacy of an herbal patch in treating osteoarthritis pain of the right or left knee.
- Trial name
- NCT01183624
- Testing
- Herbal Patch
- Where
- 12 sites in China
- Volunteers
- 626 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Osteoarthritis, Knee, Pain
A Study to Evaluate ONO-4474 in Patients With Pain Due to Osteoarthritis of the Knee
The purpose of this phase 2, randomised, double-blind, placebo controlled, parallel group, multicentre study is to investigate the efficacy, safety, tolerability and pharmacokinetics of a compound ONO-4474 in patients with…
- Trial name
- MOTION (NCT02997696)
- Testing
- ONO-4474
- Where
- 47 sites in Denmark, Hungary and 3 more
- Volunteers
- 70 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Osteoarthritis, Knee, Osteoarthritis, Hip
Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total joint arthroplasty, as compared to standard of care analgesia.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
- Trial name
- NCT02197273
- Testing
- Liposomal bupivacaine, Standard of care analgesia
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- OhioHealth
Osteoarthritis of the Knee
Apitox, Honeybee Venom Treatment for Osteoarthritis Pain and Inflammation
The study will evaluate Apitox, pure honeybee venom as a treatment for pain and inflammation of osteoarthritis of the knee.
- Trial name
- HBV (NCT00949754)
- Testing
- honeybee venom (Apitoxin (Korea) Apitox (USA))
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Apimeds, Inc.
Knee Osteoarthritis
Effects of Carbon Dioxide Infrared Laser Moxibustion on Pain and Function in Knee Osteoarthritis
Knee osteoarthritis is a prevalent degenerative joint disorder characterized by chronic knee pain, stiffness, reduced range of motion, and limitations in daily functional activities.
- Trial name
- CILM-KOA (NCT07423182)
- Testing
- Exercise Program for Knee Osteoarthritis, CO2 Infrared Laser Moxibustion (CILM)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Knee Osteoarthritis
Low-Dose Radiotherapy for Painful Knee Osteoarthritis
Knee osteoarthritis is a common cause of chronic pain and difficulty with everyday activities, particularly in older adults. Some patients continue to experience clinically relevant knee pain despite medication, therapeutic…
- Trial name
- LDRT-KOA (NCT07886697)
- Testing
- Low-Dose Radiotherapy (LDRT)
- Where
- 4 sites in Spain
- Volunteers
- 283 people
- Sponsor
- Universidad Rey Juan Carlos
Knee Osteoarthritis (Knee OA)
To Assess the Effect of 336 Days Exposure of Paractin® on Pain & Disease Progression in Patients Suffering From Osteoarthritis of Knee Joint.
Sponsor aimed to study hydroalcoholic extract of Andrographis paniculata (for its effect on OA disease progression in OA patients with moderate to severe knee OA.
- Trial name
- NCT04833946
- Testing
- Andrographis paniculata [150 mg], Microcrystalline Cellulose (MCC)
- Where
- 5 sites in India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Knee Osteoarthritis
Effectiveness of Exercise Plus Pain Neuroscience Education on Brain Function in Knee Osteoarthritis
A three-arm randomized controlled trial will be conducted. Fifty-nine participants with KOA will be recruited in a 1:1:1 ratio. Assessor, and statistician will be blinded to group allocation.
- Trial name
- NCT06482970
- Testing
- Neuromuscular exercise plus pain neuroscience education, Neuromuscular exercise
- Volunteers
- 57 people
- Sponsor
- Universidad Santo Tomas, Chile
Pain
A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain
The purpose of this study is to investigate how topical diclofenac use can improve functional mobility and physical activity primarily, as well as other quality-of-life (QoL) parameters such as sleep, mood, and engagement in…
- Trial name
- NCT06379893
- Testing
- Voltaren Gel
- Where
- 8 sites in United States, Poland
- Volunteers
- 196 people
- Sponsor
- HALEON
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