Clinical trials: Osteoarthritis Pain
Osteoarthritis Pain, Chronic Low Back Pain
Study To Assess Changes In The Number Of Nerves In The Skin At The Site Where Where Tanezumab Is Injected
Subcutaneous administration of tanezumab can result in changes in the number of nerves around the injection site in the thigh.
- Conditions
- Osteoarthritis Pain, Chronic Low Back Pain, Pain Due to Interstitial Cystitis
- Trial name
- NCT01030640
- Testing
- tanezumab
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Diabetes Mellitus Type 2, Breast Neoplasms
AI-Based Phenome Data Analysis for Predicting the Onset of Major Diseases
This study aims to develop and validate an artificial intelligence (AI)-based predictive model to estimate the risk of incident onset of five major diseases or conditions: cardiovascular disease, type 2 diabetes mellitus, breast…
- Conditions
- Diabetes Mellitus Type 2, Breast Neoplasms, Low Back Pain, Osteoarthritis
- Trial name
- NCT07595718
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Jae Yong Jeon, MD
Osteoarthritis, Osteoarthritis, Knee
A 12-Week Home-Based Electrical Stimulation Program for Strength in Adults With Knee Osteoarthritis
The purpose of this research is to investigate if a 12-week program of stimulation assisted activities can combat disuse atrophy for individuals diagnosed with knee osteoarthritis (KOA).
- Trial name
- NCT05765435
- Testing
- 12-week exercise and walking program, NMES, FES
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cionic, Inc.
Knee Osteoarthritis
Post Marketing Clinical Follow up Study of HyaleXo
Hyaluronic acid is a polysaccharide naturally present in several human tissues such as cartilage. It is the major constituent of synovial fluid and provides its viscosity and elasticity.
- Trial name
- PMCF (NCT07096050)
- Testing
- HyaleXo
- Where
- Romania
- Volunteers
- 101 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Knee Osteoarthritis
A Study of Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee
A study to assess safety, tolerability and clinical effects of single and repeat dose intra-articular administration of UBX0101 in patients with moderate to severe painful knee osteoarthritis (OA).
- Trial name
- NCT04229225
- Testing
- UBX0101
- Where
- 7 sites in United States
- Volunteers
- 35 people
- Sponsor
- Unity Biotechnology, Inc.
Osteoarthritis, Pain
fMRI and Central Sensitization in Chronic Knee Osteoarthritis. A Pre and Post TKR Study
Painful osteoarthritis (OA) is the 4th largest cause of disability in the UK. Preoperative temporal summation, a measure of central pain facilitation, has been shown to predict postoperative pain after total knee replacement…
- Conditions
- Osteoarthritis, Pain, Postoperative Pain, Surgery
- Trial name
- NCT03126279
- Testing
- Total Knee Replacement Surgery
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Knee Osteoarthritis
Effects of the Egoscue Exercises With and Without Mwm Among Patients With Knee Osteoarthritis
Knee osteoarthritis is a common degenerative joint disorder characterized by joint pain, stiffness, limited mobility, and reduced quality of life.
- Trial name
- NCT07646366
- Testing
- Egoscue exercises with MWM, Egoscue exercises without MWM
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Osteoarthritis
Qigong Therapy for Individuals With Knee Osteoarthritis
The purpose of this study is to evaluate the effectiveness of Qigong therapy, an ancient Chinese practice, for pain relief and symptom improvement in people with knee osteoarthritis (OA).
- Trial name
- NCT00104156
- Testing
- External Qigong therapy
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Osteoarthritis of the Shoulder, Corticosteroid
Comparing Platelet Rich Plasma and Corticosteroid for Military & Civilian Patients With Glenohumeral Osteoarthritis
Shoulder arthroplasty provides successful improvement in pain and function for the treatment of end stage osteoarthritis (OA) of the shoulder in the older patient population (Sanchez 2008, Sampson 2010, Kon 2012, Fitzpatrick…
- Conditions
- Osteoarthritis of the Shoulder, Corticosteroid, PRP, Pain
- Trial name
- PRP (NCT05160441)
- Testing
- Platelet Rich Plasma Injection, Corticosteroid Injection, Delayed Platelet Rich Plasma Injection After Corticosteroid Injection Failure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Walter Reed National Military Medical Center
Knee Osteoarthritis
Effectiveness and Safety of Intra-Articular Hyaluronic Acid Conjugated With Fibrinogen in Knee Osteoarthritis
This study aims to evaluate the effectiveness and safety of intra-articular injections of hyaluronic acid conjugated with fibrinogen in patients with knee osteoarthritis.
- Trial name
- NCT07323342
- Testing
- Intra-articular hyaluronic acid conjugated with fibrinogen
- Where
- Vietnam
- Volunteers
- 31 people
- Sponsor
- Cao Kim Xoa
Knee Osteoarthritis
Effectiveness of Platelet-rich Plasma Treatment of Knee Osteoarthritis
Osteoarthritis (OA) is a disease that affects the joints of the body, causing pain, stiffness, and reduced mobility. To treat knee OA, a therapy called platelet-rich plasma (PRP) is used, which involves making a concentrated…
- Trial name
- NCT05825105
- Testing
- Platelet-Rich Plasma
- Where
- Argentina
- Volunteers
- 111 people
- Sponsor
- Universidad Nacional de Entre Rios
Knee Osteoarthritis
Comparative Study Between Intra Articular Injection of Hyaluronic Acid (HA) With Platelet Rich Plasma (PRP) Versus Genicular Nerve Thermal Radiation in Management of Pain in Knee Osteoarthritis
Intraarticular injection (IAI) of Platelet rich plasma (PRP) with Hyaluronic acid (HA) Versus Radiofrequency (RF) of genicular nerve for pain reduction of of knee osteoarthritis , Improving daily activity and reduction analgesia…
- Trial name
- NCT04188561
- Testing
- Intra articular injection Group, Radiofrequency Group
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis, Knee
A Pilot Feasibility Study of IM OXT on Fear of Pain and Trust in Physical Therapist During OP Rehabilitation After TKA
This study will examine the effect that a dose of intramuscular (IM) oxytocin (naturally occurring hormone) has on fear of pain and movement and trust in the physical therapist during outpatient rehabilitation after total knee…
- Trial name
- NCT04493229
- Testing
- Oxytocin
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Knee Osteoarthritis
The Effect of "Laying on of Hands" in Older Women With Knee Osteoarthritis
Osteoarthritis (OA) is the most common form of chronic degenerative joint disease, as well as the main cause of pain and disability in older persons worldwide.
- Trial name
- NCT02917356
- Testing
- Spiritual laying on of hands (SP), Non-spiritual Laying on of Hands, Control group
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Federal University of Juiz de Fora
Knee Osteoarthritis
Ultrasound Guided Intra Articular Injection of Platelet Rich Fibrin Versus Hyaluronic Acid As Means of Pain Relief in Patients with Moderate Degree Knee Osteoarthritis
Randomised controlled trial
- Trial name
- NCT06797960
- Testing
- Ultra sound guided Injection of PRF intra articularly, Intra articular injection of HA
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Osteoarthritis
A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) Pain
CE-224535 is a new medication being developed as an analgesic and anti-inflammatory agent for the treatment of the signs and symptoms of osteoarthritis (OA).
- Trial name
- NCT00418782
- Testing
- naproxen, CE-224535
- Where
- 46 sites in United States
- Volunteers
- 212 people
- Sponsor
- Pfizer
Osteoarthritis, Hip
MONOVISC for Hip Joint Pain Relief Due to Osteoarthritis
Obtain real world, post market data to confirm the clinical improvement and safety in patients treated with a single injection of MONOVISC for the symptomatic relief of osteoarthritis in the hip joint.
- Trial name
- NCT04204083
- Testing
- Monovisc
- Where
- 4 sites in Czechia, Poland
- Volunteers
- 25 people
- Sponsor
- Anika Therapeutics, Inc.
Osteoarthritis, Knee, Knee Pain Chronic
A Phase 3 Study to Evaluate the Efficacy and Safety of Resiniferatoxin for Pain Due to Osteoarthritis of the Knee
This study evaluates the efficacy and safety of intra-articular injection of resiniferatoxin in patients with moderate to severe knee pain due to osteoarthritis.
- Trial name
- NCT04044742
- Testing
- Resiniferatoxin
- Sponsor
- Sorrento Therapeutics, Inc.
Osteo Arthritis Knee
Analgesic Potential of Light Therapy in Knee Osteoarthritis
Managing joint pain is one of the main goals for treating osteoarthritis (OA) and other musculoskeletal disorders. Alleviating chronic pain pharmacologically has several potential drawbacks including diminishing efficacy…
- Trial name
- NCT05398666
- Testing
- White LED light, Green LED light
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Nova Scotia Health Authority
Osteoarthritis, Osteo Arthritis Knee
A Study to Assess Efficacy of Supporting Properties and Safety of ARTNEO in Patients With Knee Osteoarthritis
The goal of the interventional study is to assess the effectiveness of the supporting properties and safety of the dietary supplement ARTNEO (ARTNEO®), capsules with an average weight of 585 mg, in patients with osteoarthritis of…
- Conditions
- Osteoarthritis, Osteo Arthritis Knee, Osteoarthritis, Knee
- Trial name
- NCT06032442
- Testing
- ARTNEO, Artra
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- NPO Petrovax