Clinical trials: Osteoarthritis of Hands
Hand Osteoarthritis
Crystalline Glucosamine Sulfate Therapy in Hand Osteoarthritis
The objective of this study is to retrospectively evaluate the symptomatic effects of crystalline glucosamine sulfate (GS), prescribed for the actually approved indication of knee OA, in addition to conventional therapy, in…
- Trial name
- NCT03911570
- Testing
- Glucosamine Sulfate
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- University of Siena
Hand Osteoarthritis
Progressive Strength in Hand Osteoarthritis
Background: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase.
- Trial name
- NCT02528630
- Testing
- Progressive resistance strength training program, Joint protection and energy conservation advice
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Osteoarthritis
Effect of Diacerein on Hand Osteoarthritis
Ostearthritis is one of the most common arthritis, affecting more than 30% of aged people world-widely. The disease is characterized by pain and stiffness of the affected joints and is the most common cause of disability in aged…
- Trial name
- NCT00685542
- Testing
- diacerein
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Hospital
Neuropathic Pain
Neuropathic Pain Symptoms in Arthritis
It was aimed to compare neuropathic pain symptoms in hand osteoarthritis and rheumatoid arthritis.
- Trial name
- NCT05975281
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Thumb Osteoarthritis, Hand Osteoarthritis
Assessment and Comparison of Efficacy of Intra-Articular PRP and Corticosteroid in First CMC Joint OA Treatment
Aim: We aim to determine and compare the efficiency of single dose intra-articular (IA) platelet rich plasma (PRP) and corticosteroid (CS) injections for the treatment of first carpometacarpal joint osteoarthritis (1.
- Conditions
- Thumb Osteoarthritis, Hand Osteoarthritis, Platelet Rich Plasma, Corticosteroid
- Trial name
- NCT06657300
- Testing
- PRP, Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Osteoarthritis of the Hand
AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint
This study will evaluate the safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the basal thumb joint.
- Trial name
- NCT02762760
- Testing
- AMPION™, Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Hand Osteoarthritis, Osteoarthritis
Investigation of the Effectiveness of Short Wave Diathermy Treatment in Patients With Hand Osteoarthritis
The aim of this randomized, double-blind, placebo-controlled study was to evaluate the effects of shortwave diathermy therapy on pain, grip strength, and functionality in patients with hand osteoarthritis.
- Trial name
- NCT06739096
- Testing
- Short Wave Diathermy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Omer Sezgin
Thumb Osteoarthritis, CMC
3D-Printed Hand Orthosis Versus Thermoplastic Orthosis
This study will investigate the effectiveness of 3D-printed splints for treating thumb osteoarthritis (CMC OA). These splints are made by Occupational Therapists and Physical Therapists out of low-temperature plastic and formed…
- Conditions
- Thumb Osteoarthritis, CMC, Splints
- Trial name
- NCT05896410
- Testing
- splint (orthosis)
- Volunteers
- 10 people
- Sponsor
- Western University, Canada
CBD, Hand Osteoarthritis
Is Topical CBD Effective in Treating Thumb Joint Arthritis
Rationale: CBD is commonly being used as an over-the-counter treatment for arthritis-related pain, however no clinical trial has been performed to establish efficacy.
- Trial name
- NCT04611347
- Testing
- CBD, Shea Butter
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Thumb Carpometacarpal Osteoarthritis, Thumb Basal Joint Osteoarthritis
Mechanisms of a Dynamic Stability Approach
Background. Arthritis is the leading cause of disability in the United States and osteoarthritis (OA) of the hand affects an estimated 25.6 US residents.
- Trial name
- NCT05247398
- Testing
- Dynamic Stability Exercise Program
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Minnesota
Hands Osteoarthritis
Corticosteroid Intra-articular Injection in Hands Osteoarthritis
Objective - to evaluate the effectiveness and tolerance of intra-articular injections (IAI) of hexacetonide triamcinolone (HT) for the treatment of osteoarthritis (OA) in interphalangeal joints.
- Trial name
- NCT02102620
- Testing
- Intra-articular injection with corticosteroid, Intra-articular injection with lidocaine
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Polyarthritis
Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo
Interest of methotrexate in inflammatory rheumatisms was demonstrated since several years. At present time,there is no effective treatment against digital arthritis.
- Trial name
- ADEM (NCT01068405)
- Testing
- Methotrexate
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hand Osteoarthritis
Testing of a New Joint Protection Program
The goal of this study is to to examine the feasibility of a full-scale trial on Helping Hand, a new Joint Protection Program for Hand Osteoarthritis and to examine the acceptability of the new Joint Protection Program.
- Trial name
- "Helping Hand" (NCT06963164)
- Testing
- Helping Hand - Joint Protection Program
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis Hand
CapFlex PIP Implant RSA
Rationale: Patients with osteoarthrtis (OA) of the proximal interphalangeal (PIP) joint are commonly treated with joint arthroplasty.
- Trial name
- Capflex RSA (NCT05484089)
- Testing
- CapFlex PIP implant
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Hand Osteoarthritis
Primary Care Study With Chondroitin Sulfate and Glucosamine Hydrochloride in Hand Osteoarhritis
PICASSO has been designed to demonstrate that combination therapy with CS/GH has superior efficacy compared to placebo in pain reduction (average score reduction in Huskisson's 0 to 100 mm Visual Analogue Scale) from baseline to…
- Trial name
- PICASSO (NCT02823548)
- Testing
- Droglican
- Where
- Spain
- Volunteers
- 330 people
- Sponsor
- Bioiberica
Osteoarthritis
Efficacy and Tolerability of Mud Packs Therapy in Osteoarthritis of the Hand
Objective To assess both the short-term and the long term effectiveness of spa therapy in patients with primary hand osteoarthritis (OA) in a single blind, prospective controlled, randomized trial.
- Trial name
- mdph (NCT00773682)
- Testing
- local mud-pack therapy and balneotherapy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Siena
Osteoarthritis
Open-label Safety Extension Study of Gevokizumab in Erosive Osteoarthritis of the Hand
The purpose of this study is to evaluate the long-term safety of gevokizumab in the treatment of active inflammatory, erosive osteoarthritis of the hand.
- Trial name
- NCT02293564
- Testing
- gevokizumab
- Where
- 28 sites in United States
- Volunteers
- 312 people
- Sponsor
- XOMA (US) LLC
Osteoarthritis Hand
Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of STT Osteoarthritis
The aim of this open, prospective, multicenter trial is to evaluate the use of a sterile, devitalized, processed umbilical cord amniotic membrane implant placed in joint interposition in the treatment of STT osteoarthritis.
- Trial name
- NCT06038331
- Testing
- SclerFIX-IP
- Where
- 4 sites in France
- Volunteers
- 14 people
- Sponsor
- TBF Genie Tissulaire
Osteoarthritis
The Effects of a Knitting Program on Osteoarthritis Symptoms in Elderly Women
This pilot randomized controlled trial (RCT) studies the adherence and clinical effectiveness of a knitting program in older females suffering from hand osteoarthritis (HOA) to evaluate the acceptability of this intervention and…
- Trial name
- NCT05975229
- Testing
- Knitting and education (pamphlet), Education (pamphlet)
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Université de Sherbrooke
Reduction in Pain, Reduction of Inflammation
Hand OA AND Methotrexate Use
Osteoarthritis (OA) is a common disabling condition, for which no effective therapy currently exists. Synovitis has been demonstrated in hand OA imaging.
- Conditions
- Reduction in Pain, Reduction of Inflammation, Improvement in Function
- Trial name
- Hand OA & MTX (NCT01927484)
- Testing
- 25 mg/week oral methotrexate tablets
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- University of Alexandria