Clinical trials: Osteoarthritis of the Hip
Osteoarthritis, Hip, Hip Osteoarthritis
Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty
his study will test whether giving dexamethasone through a vein can improve pain control after total hip replacement surgery. Dexamethasone is commonly used to reduce nausea and may also help with pain, but it is not clear which…
- Trial name
- NCT07581470
- Testing
- Dexamethasone 4mg, Dexamethasone 8mg
- Where
- Poland
- Volunteers
- 198 people
- Sponsor
- Poznan University of Medical Sciences
Hip Osteoarthritis
Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With Hip Osteoarthritis
Hip osteoarthritis is associated with joint pain, physical disability, decreased muscle strength and poor health status, and the most common cause for total hip arthroplasty.
- Trial name
- PROHIP (NCT04070027)
- Testing
- Total Hip Arthroplasty, Progressive Resistance Training
- Where
- 4 sites in Denmark
- Volunteers
- 109 people
- Sponsor
- Vejle Hospital
Hip Osteoarthritis, Osteoarthritis
Development and Evaluation of a Web Based Decision Aid for Patients With Hip Osteoarthritis
The main goal of this study is assess the effectiveness of a PtDA for patients with hip osteoarthritis
- Trial name
- NCT04241978
- Testing
- Patient Decision Aid (PtDA), Brochure with general information about osteoarthritis
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Servicio Canario de Salud
Hip Osteoarthritis
REDAPT Revision Hip System With RSA
The principal objectives of the study are to evaluate early and mid-term fixation of the REDAPT revision hip stem and acetabular cup as measured by stem subsidence and proximal cup migration at 2 and 5 years post-surgery through…
- Trial name
- NCT04541693
- Testing
- Full revision, Cup revision, Stem revision
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Innovation Centre
Hip Osteoarthritis, Hip Necrosis
H1 Hip Resurfacing Arthroplasty
This is a prospective, non-randomized, consecutive series, multicentre, observational study to evaluate the clinical outcome of ceramic-on- ceramic hip resurfacing arthroplasty using the ceramic, non-porous, non-cemented H1 Hip…
- Conditions
- Hip Osteoarthritis, Hip Necrosis, Hip Dysplasia
- Trial name
- H1HRA (NCT03326804)
- Testing
- H1 Hip Resurfacing Arthroplasty
- Where
- 2 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- Embody Orthopaedic Limited
Osteoarthritis
Meloxicam SoluMatrix® Capsules vs Meloxicam Tablets to Treat Osteoarthritis Pain
The purpose of this study is to evaluate the safety and efficacy of a low dose and a high dose of Meloxicam SoluMatrix® Capsules versus Meloxicam Tablets for the treatment of pain due to osteoarthritis of the knee or hip.
- Trial name
- NCT02405793
- Testing
- Meloxicam Test Capsules, Meloxicam Tablets
- Sponsor
- Iroko Pharmaceuticals, LLC
Hip Osteoarthritis, Complications; Arthroplasty
Correlation of Spinopelvic Parameters and Acetabular Cup Orientation
In total hip arthroplasty, cup anteversion is an important factor in stability. Lewinnek's safe zone and functional anteversion are often used to assess appropriate orientation.
- Trial name
- NCT02598700
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Duke University
Orthopedic, Osteo Arthritis Knee
Energy Status and Protein Intake As Prognostic Indicators of Rehabilitative Outcomes
The proposed project is novel in its goal to establish a foundation for evidence-based rehabilitative nutrition guidelines to enhance perioperative patient care and improve post-operative rehabilitative outcomes specific to…
- Conditions
- Orthopedic, Osteo Arthritis Knee, Hip Osteoarthritis, Protein-Energy Malnutrition
- Trial name
- ESPI-PRO (NCT06734845)
- Testing
- Total Knee Arthroplasty, Total Joint Arthroplasty
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Osteoarthritis, Hip, Arthroplasty, Replacement, Hip
Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen
The primary aim of this randomised trial is to determine the effects of a short peri-operative course of treatment with a non-steroidal anti-inflammatory drug (NSAID), ibuprofen, on the long-term consequences of ectopic bone…
- Conditions
- Osteoarthritis, Hip, Arthroplasty, Replacement, Hip, Arthritis, Rheumatoid
- Trial name
- NCT00145730
- Testing
- Ibuprofen
- Volunteers
- 1,000 people
- Sponsor
- The George Institute
Total Hip Arthroplasty, Degenerative Joint Disease of Hip
G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study
The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of the G7 Acetabular Shells when used with the Vivacit-E and Longevity HXLPE liners and instrumentation in primary and…
- Conditions
- Total Hip Arthroplasty, Degenerative Joint Disease of Hip, Avascular Necrosis of Hip, Rheumatoid Arthritis of Hip
- Trial name
- NCT04754087
- Testing
- Vivacit-E and Longevity (HXLPE) Liners
- Where
- 11 sites in United States, Denmark and 3 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Osteoarthritis, Post-traumatic Arthritis
A Randomised Study to Compare Metal Ion Release and Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-Metal or a Metal-on-Metal Bearing
The purpose of this study is to monitor the performance and compare the metal ion release of two bearing combinations, ceramic-on-metal and metal-on-metal in the treatment of patients with hip joint disease requiring a total hip…
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders, Avascular Necrosis
- Trial name
- NCT00873444
- Testing
- Pinnacle™ Acetabular System
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- DePuy International
Innate Inflammatory Response, Osteoarthritis, Hip
The Immunomodulatory Effect of Sugammadex After Total Hip Replacement Surgery Under Neuraxial Anaesthesia: a Pilot Study
Monocenter randomized controlled proof of principle study to investigate the effect of sugammadex at the end of total hip replacement surgery on the postoperative innate immune function
- Trial name
- MAGIC (NCT05723406)
- Testing
- Sugammadex 100 MG/ML [Bridion]
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Radboud University Medical Center
Lumbar Spondylosis, Cervical Spondylosis
Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly
The purpose of this research is to determine if post-operative cognition will be better if the general anesthesia for surgery is done with an inhaled (gas through a breathing tube) or intravenous (medicine injected in the IV)…
- Conditions
- Lumbar Spondylosis, Cervical Spondylosis, Hip Osteoarthritis, Knee Osteoarthritis
- Trial name
- NCT00788008
- Testing
- inhalation anesthesia with isoflurane vs. TIVA with propofol
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Osteoarthritis, Hip
Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoarthritis
This is a two-part, multi-center, randomized, double-blind, placebo-controlled, parallel-group study in patients with hip OA. Approximately 70 patients will be enrolled in Part I and approximately 440 patients will be enrolled in…
- Trial name
- NCT03793010
- Testing
- FX006, Normal saline
- Where
- 32 sites in United States
- Volunteers
- 70 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Joint Pain, Knee Pain
Context Effects in Exercise Therapy for Knee and/or Hip Pain
The study is designed to investigate the effect of physical surroundings on the effect of exercise therapy for knee and hip pain.
- Conditions
- Joint Pain, Knee Pain, Hip Pain, Osteoarthritis, Knee
- Trial name
- CONEX (NCT02043613)
- Testing
- Contextually enhanced physical surroundings of exercise, Neuromuscular exercise
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- University of Southern Denmark
Hip Arthritis, Hip Osteoarthritis
Defining Optimum Cup Orientation for Hip Replacements Taking Into Account the Individual's Anatomy and Movement Patterns
The purpose of this study is to investigate and determine the optimal zone for implanting the cup component (the ball that sits in the joint socket) in a total hip replacement.
- Trial name
- NCT04633525
- Testing
- Optimum Cup Orientation
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis of Knee, Osteoarthritis Hip
Cannabinoids for Osteoarthritis Pain Effectiveness Trial
This study aims to investigate whether oral cannabis extracts can effectively manage pain caused by osteoarthritis (OA), a common joint condition affecting one in seven Canadians.
- Trial name
- COPE (NCT06878417)
- Testing
- CBD, THC
- Where
- 3 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Osteoarthritis, Knee, Osteoarthritis, Hip
Barriers and Faciliators for Physical Activity in People With RMDs
The aim of this project is to systematically survey and explore barriers and facilitators for the implementation of physical activity according to the physical activity recommendations of the European Alliance of Associations for…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Rheumatoid Arthritis, Axial Spondyloarthritis
- Trial name
- COPA (NCT06514443)
- Testing
- survey
- Volunteers
- 400 people
- Sponsor
- Anne-Kathrin Rausch
Hip Osteoarthritis
Study of the Clinical and Radiographic Results of a Fixed Polyethylene Posteriorly Stabilized Cemented Total Knee Prosthesis With a Minimum Follow-up of 1 Year.
The knee replacement market is experiencing constant growth. Alongside this growth, there is also an increasing interest in customizing implantation based on specific phenotypes to restore the morphology of the native knee.
- Trial name
- PTG-Anatomic (NCT07313449)
- Where
- France
- Volunteers
- 960 people
- Sponsor
- University Hospital, Strasbourg, France
Osteoarthritis, Knee, Osteoarthritis, Hip
Study of Hip and Knee Arthroplasty in South Africa
This multi-site, observational, prospective study aims to investigate current practice and associated outcomes for patients scheduled for elective unilateral total hip or knee arthroplasty in South Africa.This information will…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Arthritis, Rheumatoid, Arthritis Knee
- Trial name
- NCT03540667
- Where
- 9 sites in South Africa
- Volunteers
- 206 people
- Sponsor
- University of Cape Town