Clinical trials: Osteocalcin
Healthy Nutrition
Dose Estimation of Jarlsberg Cheese in Young, Active Norwegian Cross-country Skiers (XCS)
The main aim was to estimate the daily OED of Jarlsberg cheese related to increased total serum Osteocalcin (tOC) level in young, active female and male Cross-country skiers (XCS).
- Trial name
- NCT05447936
- Testing
- Jarlsberg cheese
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Meddoc
Overweight and Obesity
High Vitamin K Intake Diet Intervention Effect on Cardiovascular Risk Percentage in Young Adults
The goal of this clinical trial is to compare the effect of a high vitamin K diet intervention on vitamin K, insulin, osteocalcin serum levels and the cardiovascular risk percentage in normal weight and overweight or obese young…
- Trial name
- VKDI (NCT06250647)
- Testing
- vitamin K diet
- Where
- Mexico
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Vitamin D Deficiency
Effect of Vitamin d and Omega 3 on Osteocalcin
Assessing the combined effect of omega-3 fatty acid and vitamin D 3 on plasma osteocalcin levels
- Trial name
- NCT04005612
- Testing
- vitamin D3, omega-3 fatty acid, vitamin D3 and omega-3 fatty acid
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Overweight and Obesity, Cardiometabolic Risk Factors
Effect of Vitamin K2 Over Osteocalcin, Leptin, Cytokines, and Cardiovascular Risk in Young Adults With Overweight and Obesity
The goal of this clinical trial is to compare de effect of vitamin K2 in young adults with overweight or obesity. The main questions to answer are: What is the effect of Vitamin K2 supplementation on methylation, serum…
- Trial name
- NCT05995522
- Testing
- Vitamin K2, Cornstarch
- Where
- Mexico
- Volunteers
- 51 people
- Sponsor
- University of Guadalajara
CKD 5D, Hemodialysis
Vitamin K2 Supplementation to Activate Matrix Gla Protein (MGP) as Endogenous Inhibitor of Vascular Calcification in Hemodialysis Patients
Vascular calcification (VC) is a predictor of cardiovascular morbidity and mortality. Hemodialysis (HD) patients suffer from severe vascular calcifications.
- Trial name
- NCT01407601
- Testing
- daily supplementation of MK-7 over 6 weeks
- Where
- 3 sites in Germany
- Volunteers
- 53 people
- Sponsor
- RWTH Aachen University
Hemodialysis
Use of ETElcalcetidefor pReserving vitamiN K-dependent proteIn activiTY ITAlian Study
The goal of this Prospective Observational Study of comparative effectiveness is to provide real world evidence of the effect of Etelcalcetide in increasing actives form VKDPs levels such as BGP and MGP at 3, 9 and 18 months from…
- Trial name
- ETERNITY-ITA (NCT06352957)
- Volunteers
- 160 people
- Sponsor
- Istituto di Fisiologia Clinica CNR
Bone Metabolism Disorder, Aging Disorder
Effect of Vitamin K Supplementation on Circulating Levels of Osteocalcin on the Bone Metabolism and Aging
This is an interventional study on nutraceuticals. It is a randomized controlled, open-label, prospective, single-center study that involves the enrollment of 82 patients with osteoporosis and 41 subjects without osteoporosis.
- Conditions
- Bone Metabolism Disorder, Aging Disorder, Osteoporosis
- Trial name
- OstMARK (NCT04669782)
- Testing
- Vitamin K (MK7), Teriparatide
- Where
- Italy
- Volunteers
- 99 people
- Sponsor
- University of Milano Bicocca
Asthma
A Randomized Study Evaluating Steroid Hormone Levels, Safety And Tolerability Of GW870086X In Healthy Volunteers
GW870086X is a novel inhaled steroid that has an improved safety profile over other steroids but is also less potent. This study will look at higher doses to confirm the improved safety profile.
- Trial name
- NCT00549497
- Testing
- GW870086X
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Aging
Daily Dose Estimation of Jarlsberg Cheese in Healthy Norwegian Elderly Male and Female
Aim: To estimate OED of Jarlsberg cheese and the stabilized level of serum Osteocalcin in healthy elderly men and women. Study population consists of healthy men at least 65 years old and healthy post-menopausal women.
- Trial name
- HV-ID (NCT05434806)
- Testing
- Jarlsberg cheese
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meddoc
Osteopenia, Osteoporosis
The Long-term Effect of Daily Jarlsberg Cheese Intake in Patient With Osteopenia
Aim: To estimate the effect of daily optimal efficacy dose (OED) of Jarlsberg cheese in patients with Osteopeni (OP). Study population: Post-menopausal women and men above 55 years of age in risk of Osteoporosis Treatment: Daily…
- Trial name
- PF-JB3 (NCT06358443)
- Testing
- Jarlsberg cheese
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Meddoc
D Vitamin Deficiency, Osteocalcin
Serum Vitamin D and Gingival Crevicular Fluid Levels of Osteocalcin and N-Terminal Telopeptide
This study examines the relationship between serum vitamin D levels and bone metabolism markers-osteocalcin and N-terminal telopeptide (NTx)-in gingival crevicular fluid (GCF) of periodontally healthy and periodontitis patients.
- Conditions
- D Vitamin Deficiency, Osteocalcin, Gingival Crevicular Fluid
- Trial name
- NCT06871631
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Menopausal Patients, Chronic Periodontitis
Treatment of Periodontitis in Menopausal Patients
The goal of this clinical trial is to compare the effectiveness of polyunsaturated fatty acids (PUFAs) [omega-3] as an adjunctive treatment to scaling and root planing for menopausal women with periodontitis versus scaling and…
- Conditions
- Menopausal Patients, Chronic Periodontitis, Omega 3 Fatty Acids
- Trial name
- NCT06254118
- Testing
- Polyunsaturated Fatty Acids, olive oil
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Hadir F. El-Dessouky
Nutritional Rickets, Bone Turnover Rate Disorder
Effectiveness of Vitamin C Supplementation in Treatment of Rickets
Effectiveness of therapeutic dose of vitamin C in infants and children with nutritional rickets as an adjuvant therapy with vitamin D and calcium The study is two armed Randomized Control Trial, to validate the role of Vit C…
- Trial name
- NCT05310760
- Testing
- Vit C
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Bone Density, Overweight
Nutritional Problems After Lung and Heart Transplantation
Part 1) Bone health after transplantation - possible influence of vitamin K Part 2) Fat metabolism and endocrine parameters - possible predictors for developement of overweight after transplantation
- Trial name
- NCT00826254
- Testing
- Vitamin K
- Where
- Norway
- Volunteers
- 94 people
- Sponsor
- Oslo University Hospital
Non-Alcoholic Fatty Liver Disease, Osteoporosis
Effect of Fatty Liver Disease on Bone Density
Non Alcohlic Fatty Liver (NAFLD) is a spectrum of diseases that ranges from accumulation of fat in the liver (Hepatosteatosis) that may be accompanied by inflammation (Steatohepatitis) to necrosis, fibrosis and even cirrhosis…
- Trial name
- NCT04850547
- Volunteers
- 80 people
- Sponsor
- Sohag University
Diabetic Nephropathies
Magnesium Supplementation in Diabetic Nephropathy
Higher prevalence of hypomagnesaemia in diabetic patients with nephropathy was compared to those without nephropathy. Serum magnesium levels were significantly inversely correlated with serum creatinine and U-A/C ratio, and…
- Trial name
- NCT03824379
- Testing
- Magnesium citrate, Antidiabetic
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Polycystic Ovarian Syndrome
Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women
High ucOC may favor insulin release in lean hyperandrogenic women to compensate for impaired insulin sensitivity. Meformin is an insulin sensitizing agent will be given for these women trying to interfere with the pathophysiology…
- Trial name
- U-C OC IN PCOS (NCT02244567)
- Testing
- Metformin 850 mg twice daily for 3 months, Serum uc-oc, drug
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Hip Fracture
Nutritional Risk Factors for Hip Fracture: a Case Control Study
Low Body Mass Index (BMI) is a risk factor for hip fracture, but it is unknown if it is the low BMI per se that increases risk of hip fracture or if specific micro-nutrients contribute.
- Trial name
- NCT01738776
- Where
- Norway
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Healthy
The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children
Background of the study: Results from several studies show that vitamin K has an important function in bone metabolism. In a previous cross-sectional study conducted by our department, evidence for a poor vitamin K status of bone…
- Trial name
- NCT00402974
- Testing
- menaquinone 7
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Tooth Movement
OC and ICTP in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Treatment
The aim of this study was to evaluate the tooth movement with and without piezocision with regard to the levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen in the gingival crevicular fluid.
- Trial name
- NCT04611984
- Testing
- Piezocision, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marmara University