Clinical trials: Osteochondral Lesion of Talus, active
Osteochondral Defect
Clinical Outcome After Episealer Talus Implant in Treatment of Osteochondral Lesion of the Talus
Autologous Chondrocyte Implantation (ACI) is an appealing technique whereby cartilage is harvested from the joint in a first operation.
- Trial name
- NCT06522139
- Testing
- Implantation of Episealer Talus Implant
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Stefano Zaffagnini
Osteochondral; Defect
Autologous Osteo-periosteal Cylinder Graft Transplantation for Hepple V Osteochondral Lesions of the Talus
The trial evaluates the clinical efficacy and safety of autologous osteo-periosteal cylinder graft transplantation for Hepple V osteochondral lesions of the talus.
- Trial name
- NCT03347877
- Testing
- autologous osteo-periosteal cylinder graft transplantation, autologous osteochondral graft transplantation, autologous osteo-periosteal cylinder graft
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Talar Osteochondral Defect of Ankle, Pain
Clinical and Radiographic Outcomes After AMIC Treatment for Talus Osteochondral Lesion Trattamento Artroscopico Delle Lesioni Osteocondrali Dell'Astragalo Con Tecnica AMIC
Aim of the study is to evaluate clinical and radiographic outcomes in patients undergone all-arthroscopic autologous matrix induced chondrogenesis for symptomatic osteochondral talar lesions
- Conditions
- Talar Osteochondral Defect of Ankle, Pain, Arthroscopy
- Trial name
- NCT03371121
- Testing
- AT-AMIC (arthroscopic talus autologous matrix induced chondrogenesis)
- Where
- Italy
- Volunteers
- 103 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Cartilage Injury, Orthopedic Disorder
CAsting and REhabilitation Versus Supervised Neglect for Osteochondral Lesions of the Talus in the Pediatric Population
Rationale: OCLs (osteochondral lesions) of the talus can be congenital or can occur after trauma or in patients with juvenile idiopathic arthritis (JIA). The main complaint of an OCL is pain during weightbearing activities.
- Conditions
- Cartilage Injury, Orthopedic Disorder, Skeletal Injury, Rehabilitation
- Trial name
- CARE (NCT06220539)
- Testing
- Casting and supervised rehabilitation
- Where
- 2 sites in Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tristan Buck
Articular Cartilage Defect
Autologous Costal Osteochondral Transplantation for Talar Osteochondral Lesions
The goal of this clinical trial is to evaluate the effectiveness and safety of autologous costal osteochondral transplantation in the treatment of Hepple Stage V talar osteochondral lesions, compared with autologous…
- Trial name
- NCT05942430
- Testing
- Autologous costal osteochondral transplantation, Autologous iliac osteoperiosteal transplantation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Pilon Fractures
Talar Osteochondral Lesions With Pilon Fractures
Patients with pilon fractures have a high incidence of talar osteochondral lesions. In this study, patients will undergo ankle arthroscopy at the time of external fixation.
- Trial name
- NCT07553221
- Testing
- Diagnostic Ankle Nano-Arthroscopy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Missouri-Columbia
Osteochondral Lesions of the Talus
The Effect of Platelet Rich Plasma for the Treatment of Osteochondral Lesions of the Talus
Osteochondral lesion of the talus (OCL) results from the detachment of the talar cartilage which could also be associated with subchondral bone fragmentation due to trauma.
- Trial name
- NCT05795660
- Testing
- platelet rich plasma
- Volunteers
- 24 people
- Sponsor
- Ministry of Health, Kuwait
Chondral Defect, Articular Cartilage Defect
A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle
The objective of this study is to demonstrate the superiority of MACI (autologous cultured chondrocytes on porcine collagen membrane) versus Bone Marrow Stimulation in the treatment of patients aged 17 to 65 years with…
- Trial name
- MASCOT (NCT06915233)
- Testing
- autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation
- Where
- 12 sites in United States
- Volunteers
- 309 people
- Sponsor
- Vericel Corporation
Osteochondral Lesion of Talus, Microfractures
Microfracture With Platelet Rich Plasma Gel Injection for Osteochondral Lesion of the Talus
The goal of this clinical trial is to learn if combined local injection of platelet rich plasma (PRP) gel adds clinical efficacy to isolated arthroscopic microfracture in treatment of osteochondral lesion of the talus (OLT).
- Conditions
- Osteochondral Lesion of Talus, Microfractures, Platelet Rich Plasma
- Trial name
- NCT06358807
- Testing
- Arthroscopic microfracture with intraoperative local PRP gel injection, Isolated microfracture
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Osteochondral Defect of Talus
Ten Years Follow-up After the Arthroscopic Repair of Osteochondral Lesions of the Talus Via Autologous Matrix-induced Chondrogenesis (AMIC)
This clinical study evaluates the long-term, ten-year clinical and functional outcomes of patients who underwent arthroscopic repair of osteochondral lesions of the talus (OLT) using the autologous matrix-induced chondrogenesis…
- Trial name
- AMIC10Y (NCT07725770)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio