Clinical trials: Osteomyelitis
Musculoskeletal Infection, Acute Hematogenous Osteomyelitis
Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal Infections
The purpose of this study is to evaluate the use of a blood test: Karius® plasma-based next-generation sequencing test (Karius Test), to see if we can detect and measure the infection causing agent in children with…
- Conditions
- Musculoskeletal Infection, Acute Hematogenous Osteomyelitis, Septic Arthritis, Osteomyelitis
- Trial name
- KDG-002 (NCT03846804)
- Testing
- Karius Test
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Indiana University
Osteomyelitis
RETR(Osteomyelitis)
This is a retrospective study describing the management of osteomyelitis in a referece center, with success and failures.
- Trial name
- NCT04936958
- Testing
- patients having had an osteomyelitis since 2017
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Diabetic Foot Osteomyelitis
White Blood Cell SPECT/CT and Diabetic Foot Osteomyelitis
Osteomyelitis is a risk factor for lower extremity amputation in diabetic people. Antibiotic therapy allows a remission in 60 to 80% of cases.
- Trial name
- NCT02927678
- Testing
- white blood cell SPECT/CT (Single Photon Emission Computed Tomography/Computed Tomography) imaging
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Hospices Civils de Lyon
Diabetes Mellitus, Foot Osteomyelitis
Assessment of PCR Multiplex Tests as a Tool to Obtain a Quicker Diagnosis of Bacteria Responsible for Foot Osteomyelitis Than Usual Cultures
Bone samples from infected diabetic feet will be collected and tests will be performed for the diagnosis of causative bacteria. Samples will be processed by PCR multiplex tests and usual cultures for identification of causative…
- Trial name
- RAPDIAGOS (NCT03434288)
- Testing
- Bone sampling
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Montpellier
Osteomyelitis
Effect of Pulsed Electromagnetic Field Stimulation on Localized Pediatric Osteomyelitis
This study will be applied to evaluate effect of pulsed electromagnetic field on pediatric localized osteomyelitis.
- Trial name
- PEMF (NCT06084754)
- Testing
- pulsed electromagnetic field, Antibiotics
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Osteomyelitis of Lower Extremities, Osteomyelitis - Foot
Comparison of Oral Antibiotics For Bone Infections of the Leg and Foot
The goal of this clinical trial is to compare different classes of oral antibiotics (beta-lactam and non-beta-lactam antibiotics) for the treatment of bone infections of the leg and foot.
- Conditions
- Osteomyelitis of Lower Extremities, Osteomyelitis - Foot, Osteomyelitis of the Foot
- Trial name
- OSTEO (NCT07266753)
- Testing
- Oral Beta-Lactam Antibiotic, Oral Non-Beta-Lactam Antibiotic
- Where
- 3 sites in Canada
- Volunteers
- 1,418 people
- Sponsor
- Michael Garron Hospital
Chronic Rhinosinusitis
Computed Tomography (CT) Score and Histopathology of the Middle Turbinate in Chronic Rhinosinusitis
In a previous study (Berger el al. Old and new aspects of middle turbinate histopathology. Otolaryngol Head Neck Surg. 2009;140:48-54), the investigators reported significant histopathologic changes in the middle turbinate mucosa…
- Trial name
- CT (NCT00899561)
- Where
- 2 sites in Israel
- Volunteers
- 45 people
- Sponsor
- Meir Medical Center
Bacterial Infections, Bacteremia
Procalcitonin Level and Kinetics in Children With Bacterial Infections
The purposes of this study are: 1. To determine whether procalcitonin level at admission of pediatric patients with bacterial infections can be used as a marker for prediction of defervescence and hospitalization length 2.
- Conditions
- Bacterial Infections, Bacteremia, Meningitis, Urinary Tract Infection
- Trial name
- NCT00714402
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Osteomyelitis
CERAMENT™|G - Bone Healing and Re-infection Prophylaxis
The surgical management of long bone infections is often challenging. Adequate surgical debridement decreases the bacterial load, removes dead tissues, and gives a chance for the host immune system and antibiotics to arrest…
- Trial name
- NCT02128256
- Testing
- Cerament G
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Dr. Olivier Borens
Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis
CHronic Nonbacterial Osteomyelitis International Registry
The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease…
- Trial name
- CHOIR (NCT04725422)
- Testing
- Methotrexate, Sulfasalazine, Leflunomide
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Seattle Children's Hospital
Diabetic Foot Infection, Osteomyelitis
A Clinical Trial Testing the Efficacy of PDT in Preventing Amputation in Diabetic Patients
The feet of diabetic patients continue to be an important problem in medicine. In general, patients with diabetic foot have some sort of amputation, especially in underserved populations.
- Conditions
- Diabetic Foot Infection, Osteomyelitis, Photo Antimicrobial Chemotherapy
- Trial name
- NCT03380403
- Testing
- PDT, Ciprofloxacin
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Faculdade de Medicina do ABC