Clinical trials: Osteopenia
Osteopenia
DXA Precision and Accuracy Comparison Study
This study is being conducted to examine the performance of three common DXA machines (1) Lunar iDXA, (2) Lunar Prodigy and (3) Hologic Discovery A in measuring bone density and body fat.
- Trial name
- DXA P&A (NCT01530477)
- Testing
- Lunar Prodigy (GEHC), Lunar iDXA (GEHC), Discovery A (Hologic
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Alveolar Bone Loss, Alveolar Ridge Augmentation
A Novel Approach for Horizontal Augmentation: A Split Box
The goal of this clinical study is to investigate the effectiveness of the split-box technique in systemically healthy, non-smoking, over 18 years of age, participants with narrow crests (<5mm bone width) and adequate bone height…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Augmentation, Augmentation, Alveolar Ridge
- Trial name
- NCT06177899
- Testing
- Splitting of bone and fixation of bone laminae differ between the 3 groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Marmara University
Bone Loss, Alveolar
Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts
In patients with a single non restorable tooth, does filling the peri-implant buccal gap with alloplastic sticky grafts result comparable results compared to xenogenic sticky grafts?
- Trial name
- NCT06653868
- Testing
- Immediate dental implant with filling the peri implant gap with xenogenic sticky bone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer, Osteoporosis
Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer
RATIONALE: Zoledronate may reduce bone loss in patients receiving letrozole for breast cancer. PURPOSE: This clinical trial is studying how well zoledronate works in treating osteopenia or osteoporosis in postmenopausal women…
- Trial name
- NCT00436917
- Testing
- zoledronic acid, Letrozole as adjuvant therapy
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Osteopenia
Herbal Teas on Bone Health in an Osteopenic Population
The project goal is to identify if herbal teas consumed three times per day over a period of three months can improve these markers of bone health as well as improve quality of life (QOL) compared to women taking placebo by…
- Trial name
- OsTea (NCT03480126)
- Testing
- Herbal Teas
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Paula Witt-Enderby
Marginal Bone Loss Around Implants
Radiographic and Retention Evaluation Over Seven Years for Four Implant Retained Overdenture
ABSTRACT Statement of the problem: Insufficient long-term retrospective data is evaluating marginal bone loss and retention of four-implant Locator-retained mandibular overdentures.
- Trial name
- NCT07536776
- Testing
- implant retained overdenture, four dental implant with locator attachment
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Mansoura University
Periodontitis, Periodontal Pocket
Injectable PRF in Non-Surgical Periodontal Treatment
This study aims to evaluate the clinical and microbiological effects of using injectable Platelet-Rich Fibrin (i-PRF) as an adjunct to non-surgical periodontal therapy (scaling and root planing) in patients with periodontitis.
- Conditions
- Periodontitis, Periodontal Pocket, Alveolar Bone Loss
- Trial name
- IPRF-PERIO (NCT07375004)
- Testing
- Injectable Platelet-Rich Fibrin (i-PRF)., Scaling and Root Planing (SRP).
- Where
- Iraq
- Volunteers
- 18 people
- Sponsor
- Al-Mustansiriyah University
Breast Neoplasms, Bone Loss
Bone Loss Treatment From Adjuvant Zoledronate Efficacy
The main purpose of this study is to observe and assess the impact of adjuvant zoledronate on bone density in breast cancer patients.
- Trial name
- BLAZE (NCT01623908)
- Testing
- Zoledronate
- Where
- 10 sites in China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Dental Implant, Implant Stability
Analysising the Marginal Bone Loss, Torque and Implant Stability Placed in Bone and Tissue Level Dental Implants
It is a prospective clinical study to compare two implants of the same brand of a similar design for implantation [either at the bone tissue level or at the soft tissue level], in order to evaluate the marginal bone loss of each…
- Trial name
- NCT07288606
- Testing
- Dental implant placement
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Barcelona
Osteoporosis
Magnesium Supplementation to Prevent Bone Loss
Extreme magnesium deficiency is known to have an impact on the synthesis, secretion and/or action of calcium regulating hormones.
- Trial name
- NCT00346658
- Testing
- magnesium
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Alveolar Bone Loss
Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
The aim of this trial is to compare whole-tooth vs particulate dentin for their effects in alveolar ridge preservation.
- Trial name
- NCT05336149
- Testing
- Alveolar ridge preservation using whole-tooth dentin graft, Alveolar ridge preservation using particulate dentin graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Limb Fracture, Bone Loss
An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects
Long bone defect (LBD) is defined as a focalized loss of bone tissue in any long bone of the upper or lower extremity. Long bone defects are a complex problem, that may arise as a complication of many different pathologies, such…
- Trial name
- NCT04112992
- Testing
- Any treatment that is used for a defect of any long bone
- Where
- 21 sites in United States, Australia and 12 more
- Volunteers
- 600 people
- Sponsor
- AO Innovation Translation Center
Critical Illness, Kidney Injury
Assessment of Kidney Function and Osteomuscular Status After Critical Care
This observational study aims to assess kidney function through direct glomerular filtration rate (GFR) using iohexol clearance, compared to estimated GFR based on creatinine and cystatin C equations.
- Conditions
- Critical Illness, Kidney Injury, Muscle Loss, Bone Loss
- Trial name
- NCT04980092
- Testing
- one-year follow-up
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University of Liege
Alveolar Bone Loss
Effectiveness of Alveolar Bone Preservation in Alveoli With Infectious Process
Alveolar ridge preservation (ARP) is a surgical technique that aims to minimize the degree of dimensional changes following extraction.
- Trial name
- NCT06661863
- Testing
- alveolar ridge preservation with bioactive glass, alveolar ridge preservation with autologous bone
- Where
- Ecuador
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Alveolar Bone Loss, Dental Implant
Evaluation of the Effect of Periimplant Soft Tissue Phenotype on Marginal Bone Loss
The goal of this clinical trial to test the effect of periimplant soft tissue phenotype in the participants with implant placed and at least 1 year after implant loading. The main questions it aims to answer are: 1.
- Conditions
- Alveolar Bone Loss, Dental Implant, Periimplantitis
- Trial name
- NCT05640284
- Testing
- Nuclear Factor-Kappa B Ligand (RANKL) analysis, Osteoprotegerin (OPG) analysis, Tumor Necrosis Factor Alpha (TNF-α) analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Necmettin Erbakan University
Bone Loss, Periodontitis
Impact of Parathyroid Hormone (PTH) on Osseous Cavity
Parathyroid hormone (PTH) has potent bone-building actions and has been approved for the treatment of osteoporosis as FORTEO by Eli Lilly \& Co.
- Trial name
- NCT00277706
- Testing
- Periodontal surgery, FORTEO, Vitamin D and Calcium
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Osteoporosis
Radiological Biological Genetic and Micro-architectural Bone Determinants of Fractures in Men With Low Bone Mineral Density
Rational: Osteoporosis in men is responsible for one third of fragility fractures. However the definition and especially the determinants of fracture in humans are less well known than in women.
- Trial name
- OSTEHOM (NCT01250314)
- Testing
- Radiology, Biological, biochemical and genetic samples
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes
Risk Factors for Implant Bone Loss in Patients With Diabetes Mellitus
Dental implants are regarded as a standard of care in restoring missing teeth. Although there is a high prevalence of diabetics who receive dental implants, the relationship between dental implants and diabetes has not clearly…
- Trial name
- NCT00933491
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bone Loss
Comparison of Straumann Bone Ceramic and Bio-Oss With Guided Tissue Regeneration for Alveolar Ridge Preservation
The purpose of this study is to compare a new biomaterial with an already existing treatment principle (Bio-Oss/Bio-Gide) with regard to their ability to preserve the dimensions of the alveolar ridge and to promote bone…
- Trial name
- NCT00900718
- Testing
- Straumann Bone Ceramic, Bio-Oss
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Institut Straumann AG
Peri Implant Bone Loss
Effect of Two Different Digital Construction Techniques of Implant-assisted Overdentures
twenty patients received mandibular overdenture constructed by different construction techniques were classified equally and randomly into two groups peri implant bone loss was assessed by CBCT at baseline (T0), at1 year(T1), at…
- Trial name
- NCT06720389
- Testing
- peri implant bone loss was assessed by CBCT, posterior ridge resorption was assessed by CBCT
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University