Clinical trials: Osteopenia
Osteoporosis, Osteopenia
The Effect of Exercise in Postmenopausal Women with Low Bone Density
This clinical trial aims to evaluate the effects of a 12 month gym- and home-based exercise program on bone density and falls risk factors in postmenopausal women with low bone density.
- Trial name
- NCT00643331
- Testing
- Exercise
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Low Back Pain, Osteopenia
Effect of Manual Therapy on Low Back Pain in Osteopenic Postmenopausal Women
The purpose of this study is to determine the effect of manual therapy on low back pain in osteopenic postmenopausal women.
- Trial name
- NCT06671665
- Testing
- calcium supplementation, Manual therapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Osteoporosis, Osteopenia
Effectiveness of the Adherence for Exercise Rehabilitation in Older People (AERO) Program in People with Osteoporosis
The goal of this pilot study is to investigate the effect of an evidence-based adherence promoting intervention on exercise adherence of patients with osteoporosis.
- Conditions
- Osteoporosis, Osteopenia, Bone Loss
- Trial name
- NCT06164847
- Testing
- AERO Program, Standard Care
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Hochschule Osnabruck
Type 1 Diabetes, Osteopenia
Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk
Patients with Type 1 Diabetes Mellitus (T1DM) have a higher risk of low-trauma (osteoporotic) fracture that is 7-12 times higher than non-diabetics.
- Conditions
- Type 1 Diabetes, Osteopenia, Bone Loss, Fractures, Bone
- Trial name
- NCT05701254
- Testing
- Transilial bone biopsy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Creighton University
Osteopenia, Osteoporosis
Safety And Tolerability Study Of RN564 In Women With Osteopenia And Healthy Men.
The purpose of this study is to determine the safety and tolerability of RN564 in women with osteopenia and healthy men.
- Conditions
- Osteopenia, Osteoporosis, Bone Disease
- Trial name
- NCT01293487
- Testing
- RN564
- Where
- 8 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Pfizer
Osteoporosis, Osteopenia
The Impact of Hormonal Contraceptive Use and Lifestyle Factors on Fracture Risk and Bone Quality in Young Female Adults
The study on hand is based on a cross-sectional design and aims to acquire 1) descriptive data on the physical state and health condition of female soldiers in the German armed forces.
- Conditions
- Osteoporosis, Osteopenia, Fracture Reduction, Body Composition
- Trial name
- FH (NCT06608862)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bundeswehr University Munich
Osteopenia
Food Trial Evaluating the Efficacy of SBD111 Versus Placebo for the Clinical Dietary Management of the Metabolic Processes of Osteopenia
The aim of the trial is to determine if the SYNBIOTIC (prebiotic and probiotic), provided twice daily (capsule) will help support skeletal health in otherwise healthy postmenopausal women in the early years postmenopause (1-6…
- Trial name
- NCT05009875
- Testing
- Medical Food SBD111
- Where
- Australia
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Solarea Bio, Inc
Osteopenia, Low Bone Density
Evaluation of the Effect of Spry Belt Treatment on Bone Turnover Marker Profile
To conduct a sham-controlled study to rigorously evaluate the effect of Spry Belt treatment on key bone turnover markers (BTMs) over a 12-week period.
- Trial name
- NCT05457036
- Testing
- Spry Belt
- Where
- 2 sites in United States
- Volunteers
- 94 people
- Sponsor
- Bone Health Technologies, Inc.
Osteopenia
Comparison of Tibolone and Raloxifene on Bone Mineral Density in Osteopenic Postmenopausal Women (P06090)
Both tibolone and raloxifene have been demonstrated to prevent postmenopausal bone loss. During treatment with tibolone bone mineral density (BMD) of the spine has been shown to be increased between 1.8 and 5.8 % above baseline…
- Trial name
- STEP (NCT00431431)
- Testing
- tibolone, raloxifen
- Volunteers
- 324 people
- Sponsor
- Organon and Co
Osteopenia or Osteoporosis
The Effect of Pre-exercise Feeding on Bone Turnover Biomarkers
Osteoporosis is a major contributor to loss of independence due to bone fractures and resulting hospital treatments lead to significant morbidity.
- Trial name
- NCT06550466
- Testing
- Breakfast only, FAST, FED
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Postmenopausal Osteopenia, Bone Loss, Age Related
OsteoPreP: Food Supplements for Postmenopausal Bone Health
To evaluate the effect of 12 months of supplementation with a probiotic (probiotic plus prebiotic; 2 capsules per day) on relative change (%) in total volumetric bone density (measured using high resolution peripheral…
- Conditions
- Postmenopausal Osteopenia, Bone Loss, Age Related, Age-Related Sarcopenia, Glucose Metabolism Disorders
- Trial name
- OsteoPreP (NCT05348694)
- Testing
- Pendulum WBF-038
- Where
- Australia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Australian Catholic University
Osteopenia
Effectiveness of Calcium and Vitamin D, With and Without Collagen Peptide, in Enhancing Bone Mineral Density on Postmenopausal Women With Osteopenia
Osteopenia is characterized by bone mineral density (BMD) being lower than normal but not reaching the osteoporosis threshold, poses a serious problem for women after menopause.
- Trial name
- NCT06464718
- Testing
- Fortibone, Chewable Tablet
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Frontier Medical and Dental College, Abbotabad
Osteoporosis, Osteoporosis, Postmenopausal
Efficacy of Zoledronic Acid to Prevent Bone Loss Following Denosumab Discontinuation
This two-year observational, open-label clinical trial will evaluate the efficacy of a once-yearly infusion of zoledronic acid after denosumab discontinuation to maintain tissue mineral density and bone microarchitecture using…
- Conditions
- Osteoporosis, Osteoporosis, Postmenopausal, Osteopenia, Bone Loss
- Trial name
- NCT05405894
- Testing
- Zoledronic acid
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Rheumatoid Arthritis, Osteoporosis
A Study on the Prevention and Treatment of GIOP With Eldecalcitol
The study will be a multi-center, randomized, open label, parallel trial conducted in rheumatoid arthritis patients treated with glucocorticoids.
- Conditions
- Rheumatoid Arthritis, Osteoporosis, Osteopenia
- Trial name
- ELEGANT (NCT06385093)
- Testing
- Eldecalcitol capsules, Alfacalcidol tablets, Calcium carbonate tablets
- Where
- 7 sites in China
- Volunteers
- 314 people
- Sponsor
- Chinese SLE Treatment And Research Group
Postemenopusal Women With Osteopenia
Effect of Raloxifene Plus Cholecalciferol and Cholecalciferol Alone on the Bone Mineral Density in Postmenopausal Women With Osteopenia
Osteoporosis is a very strong predictor of fractures with low BMD, but more than half of osteoporotic fractures actually occur in the osteopenic patient group.
- Trial name
- NCT05386784
- Testing
- Raloxifene plus cholecalciferol, Cholecalciferol
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Yonsei University
Osteoporosis, Osteopenia, Hypercholesterolemia
Effect of Pitavastatin on Bone
This clinical trial investigates the effects of pitavastatin on bone health in postmenopausal women with osteopenia or osteoporosis and hypercholesterolemia.
- Conditions
- Osteoporosis, Osteopenia, Hypercholesterolemia, Menopausal Osteoporosis
- Trial name
- NCT06359353
- Testing
- Pitavastatin
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoporosis, Osteopenia
Effects of OsteoStrong vs. Individually Adapted and Combined Training on Bone Health
The aim of this clinical trial is to investigate the effect of the OsteoStrong training method and the Individually Adapted and Combined Training on the bone health of older women with high fracture risk.
- Conditions
- Osteoporosis, Osteopenia, Bone Density, Low, Bone Loss
- Trial name
- NCT05721014
- Testing
- OsteoStrong, Individually Adapted and Combined Physical Training
- Where
- Sweden
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Sarcopenia, Osteopenia
Effect of a Ghrelin Receptor Agonist on Muscle and Bone
Adults with low muscle mass also usually have low bone mass, making them vulnerable to falls, fractures and other injuries. This project will determine the effectiveness of treatment with a ghrelin receptor agonist in improving…
- Trial name
- NCT04021706
- Testing
- Anamorelin Hydrochloride
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tufts University
Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Osteopenia
Denosumab in Treating Patients With Bone Loss Due to Donor Stem Cell Transplant
This Phase II trial studies the side effects of denosumab and to see how well it works in treating patients with bone loss who have received a donor stem cell transplant.
- Conditions
- Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Osteopenia, Osteoporosis
- Trial name
- NCT03925532
- Testing
- Denosumab
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Roswell Park Cancer Institute
Osteopenia, Postmenopausal Osteopenia
Design and Development of a Novel Food Supplement for Osteoporosis Based on Gut Microbiome Mechanisms
It is well proven that the intestinal microbe regulates bone metabolism by the absorption of calcium and other metallic trace elements.
- Trial name
- OSTEOME (NCT05421819)
- Testing
- Calcium and vitamin D supplement, Calcium, vitamin D and prebiotic supplement, Calcium, vitamin D and flavonoid supplement
- Where
- Greece
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens