Clinical trials: Osteopenia or Osteoporosis, active
Critical Illness, Osteoporosis
Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults
The Bone Zone trial is a prospective, multi-centre, double-blind, phase II, randomised controlled trial evaluating the effect of denosumab or zoledronic acid compared to placebo on change in bone mineral density over one year in…
- Trial name
- BoneZone (NCT04608630)
- Testing
- Denosumab 60 MG/ML, Zoledronic Acid 5Mg/Bag 100Ml Inj, Sodium Chloride 0.9% or 5% Dextrose Intravenous
- Where
- 22 sites in Australia, New Zealand
- Volunteers
- 450 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Osteoporosis, Postmenopausal, Osteopenia
High-Intensity Laser Therapy and Physiotherapy for Bone Health in Postmenopausal Women: A Randomized Trial
The goal of this clinical trial is to learn if adding high-intensity laser therapy (HILT) to a physiotherapy programme helps bone health in women after menopause who have low bone density (osteopenia or osteoporosis).
- Trial name
- NCT07734922
- Testing
- High-Intensity Laser Therapy, Standardised Physiotherapy Programme
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Osteopenia or Osteoporosis
Strenght Training in Osteoporosis Prevention
The study involves 120 women over the age of 50. All participants in the study take part in high-intensity strength training for 10 months. In addition, half of the participants receive vitamin D3 at a dose of 4,000 IU/day.
- Trial name
- SPORT (NCT06733064)
- Testing
- Supplementation of vitamin D3
- Where
- 2 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Mateusz Karnia
Osteoporosis Risk, Bone Loss
Comparison of Bone Microarchitecture Analysed by HRpQCT and pQCT in Pathologies With Bone Loss and/or Muscle Loss
The study aims to utilize medical devices, such as the Xtreme CT and XCT 3000, to assess bone and muscle microarchitecture for various pathologies.
- Trial name
- MICROS (NCT06541548)
- Testing
- HR-pQCT, pQCT, DEXA
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Change in Bone Mineral Density, Bone Loss
LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
The primary objective of this study is to evaluate the impact of LF111 and drospirenone (DRSP) 3.5 mg chewable tablets on bone mineral density (BMD) at the lumbar spine after 12 months (13 medication cycles) of investigation in…
- Trial name
- NCT05303636
- Testing
- drospirenone 4 mg oral tablet or drospirenone 3.5 mg chewable tablet
- Where
- 37 sites in United States, Czechia and 1 more
- Volunteers
- 1,536 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
Osteopenia or Osteoporosis
Profylactic Treatment for Patients in Risk Osteoporosis
The aim is to compare the daily intake of Calsium (Ca) + vitamin D with and without daily optimal efficacy dose (OED) of Jarlsberg on Bone Mineral Density (BMD) and bone markers (BM) to Osteopeni patients (OP).
- Trial name
- PF-Jarlsberg (NCT05787808)
- Testing
- Calsium, Vitamin D, Jarlsberg cheese
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meddoc