Clinical trials: Osteoporosis, Osteopenia
Osteopenia, Osteoporosis
Study of Bone Disease in Older HIV-infected Adults
This study will look to see if there are changes in the blood cells that are associated with bone disease and sort out effects that are due to the HIV virus itself, the medications and see if faster aging occurs in the cells of…
- Conditions
- Osteopenia, Osteoporosis, HIV Infection, Aging
- Trial name
- NCT00935935
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Ruth M. Rothstein CORE Center
Osteoporosis, Osteopenia
Controlled Study of ONO-5334 in Postmenopausal Women With Osteopenia or Osteoporosis
The purpose of this study is to evaluate the efficacy and safety of ONO-5334 in postmenopausal women with osteopenia or osteoporosis.
- Trial name
- NCT00532337
- Testing
- ONO-5334
- Where
- Netherlands
- Volunteers
- 285 people
- Sponsor
- Ono Pharma USA Inc
Osteoporosis, Osteopenia
Study to Evaluate Effect of Intranasal Teriparatide on Serum P1NP, a Biomarker of Bone Formation, in Postmenopausal Women With Low Bone Mass
This study is being conducted to evaluate the effect treatment has on serum P1NP levels, a biomarker of bone formation in postmenopausal women with low bone mass.
- Trial name
- NCT01604057
- Testing
- ZT-034 Low Dose Nasal Spray, ZT-034 Mid Dose Nasal Spray, ZT-034 High Dose Nasal Spray
- Volunteers
- 130 people
- Sponsor
- Azelon Pharmaceuticals
Osteoporosis, Osteopenia
Effect of Assessing Risk for Osteoporosis on Physician and Patient Behaviors
The study seeks to determine the impact of assessing risk for osteoporosis in women on patient and physician behaviors through a pharmacist directed osteoporosis screening program.
- Trial name
- NCT01572766
- Testing
- FRAX Assessment Tool
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Osteoporosis, Osteopenia
The Effect of Chymosin on the Intestinal Absorption of Calcium
An adequate calcium intake is important for bone turnover and the risk of developing osteoporosis. Yet many studies have documented that supplementation with calcium tablets are often associated with a poor compliance, therefore…
- Trial name
- Chymosin (NCT01370941)
- Testing
- Drug A Chymosin
- Where
- Denmark
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoporosis, Osteopenia
Melatonin Osteoporosis Prevention Study
Osteoporosis is one of the most common skeletal disorders. Today in the United States, 10 million individuals have osteoporosis and 34 million more have low bone mass or osteopenia, which places them at an increased risk of some…
- Trial name
- MOPS (NCT01152580)
- Testing
- melatonin, sugar pill
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Women, Osteoporosis
Temporomandibular Disorders and Osteoporosis
Increased life expectancy has attracted research attention, interested in provide a quality and healthy aging. According to the latest census conducted in 2010 by IBGE, Brazilian population consists of 97,342,162 women, whom…
- Conditions
- Women, Osteoporosis, Osteopenia, Temporomandibular Disorder
- Trial name
- TMDOST (NCT01029210)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Osteopenia, Osteoporosis
Creatine Supplementation and Bone Mass
Resistance training as well as creatine supplementation may increase bone mass. Therefore, the investigators speculate that resistance training combined with creatine supplementation would promote additive benefits on bone mass…
- Trial name
- NCT01163370
- Testing
- creatine supplementation, exercise training
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Osteoporosis, Osteopenia
High Dosage Vitamin D and Osteoporosis
Vitamin D and calcium are essential in the treatment and prevention of osteoporosis. What dosage of vitamin D which is the ideal one, is not yet clear. We want to test the hypothesis that high dosage of vitamin D (i.e.
- Trial name
- NCT00491920
- Testing
- cholecalciferol (Vitamin D3)
- Where
- Norway
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Osteoporosis, Osteopenia
Effect of Exercise Training and Soy-based Nutritional Supplementation on Prevention of Osteoporosis
The purpose of the study is to determine the effectiveness of combining exercise training (i.e. weight lifting and walking) and dietary supplementation with a soy-based nutritional supplement for increasing bone mineral density.
- Trial name
- NCT00204425
- Testing
- exercise/soy isoflavone
- Where
- Canada
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Osteoporosis, Osteopenia
A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
The purpose of this study is to determine whether in postmenopausal women with low bone mineral density, the mean percent change in total hip BMD in subjects receiving denosumab is not less than that observed in subjects…
- Trial name
- NCT00330460
- Testing
- Alendronate, Denosumab
- Volunteers
- 1,189 people
- Sponsor
- Amgen
Bone Density, Osteopenia
The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces…
- Conditions
- Bone Density, Osteopenia, Osteoporosis, Post-Menopause
- Trial name
- NCT00420940
- Testing
- Juvent 1000 Dynamic Motion Therapy (DMT) Platform
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Osteopenia
Tai Chi for Osteopenic Women
This study will assess the effectiveness of Tai Chi to affect the rate of bone loss in post-menopausal women who have been diagnosed with the initial stages of bone thinning.
- Trial name
- NCT01039012
- Testing
- Tai Chi, Standard Care
- Where
- 2 sites in United States
- Volunteers
- 86 people
- Sponsor
- Harvard University Faculty of Medicine
COPD, Osteoporosis
Osteoporosis and Chronic Obstructive Pulmonary Disease (COPD)
The goals of the trial are: To determine the prevalence of osteoporosis in subgroups of COPD patients. To look for risk factors of osteoporosis in COPD patients.
- Conditions
- COPD, Osteoporosis, Osteopenia
- Trial name
- NCT00231127
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Osteoporosis, Osteopenia
Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women
Osteopenia and osteoporosis cause thinning of bone tissue and loss of bone density over time. The purpose of this study is to determine the safety and effectiveness of nitroglycerin ointment for the treatment of osteopenia in…
- Trial name
- NCT00043719
- Testing
- Nitroglycerin ointment, Calcium supplement with vitamin D
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Crohn's Disease, Osteopenia
Zoledronate for Osteopenia in Pediatric Crohn's
Background: Up to 30% of children and adolescents with Crohn's disease have decreased bone strength, or decrease bone density, called osteopenia.
- Conditions
- Crohn's Disease, Osteopenia, Osteoporosis
- Trial name
- NCT00798473
- Testing
- zoledronic acid, IV saline infusion
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
HIV Infections, Osteopenia
Bisphosphonate Therapy for HIV-Infected Adults With Decreased Bone Mineral Density
Bisphosphonates are a type of drug used to prevent and treat bone loss. The purpose of this study is to determine if zoledronate, an investigational bisphosphonate, can improve bone mineral density (BMD) in HIV-infected adults.
- Conditions
- HIV Infections, Osteopenia, Osteoporosis
- Trial name
- NCT00102908
- Testing
- Zoledronate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Osteoporosis, Postmenopausal, Osteopenia
Influence of Alfacalcidol on Falls in Osteopenic/Osteoporotic Postmenopausal Women (ALFA Study)
The purpose of this study is to evaluate the effect of alfacalcidol 1 µg daily on the number of fallers in postmenopausal, alendronate-treated, osteopenic or osteoporotic women.
- Conditions
- Osteoporosis, Postmenopausal, Osteopenia, Falls
- Trial name
- NCT00168909
- Testing
- alfacalcidol
- Where
- 2 sites in Germany
- Volunteers
- 282 people
- Sponsor
- Charite University, Berlin, Germany
Menopause, Osteopenia
Vascular and Skeletal Protective Effects of Genistein in Postmenopausal Women
The present research program is proposed deepening some pharmacological effects of the genistein therapy in order to individualize alternative treatments to the conventional hormonal replacement therapy useful to reduce the…
- Trial name
- NCT00355953
- Testing
- Genistein
- Volunteers
- 400 people
- Sponsor
- University of Messina
Osteopenia, Osteoporosis
Study to Evaluate Effect of Intranasal Teriparatide on Bone Mineral Density in Postmenopausal Women With Low BMD
This study is being conducted to compare the effect of increasing nasal teriparatide dosing on percent change in Bone Mineral Density (BMD) of the lumbar spine after 24 weeks of therapy in postmenopausal women with low bone…
- Trial name
- NCT00624481
- Testing
- Teriparatide, Teriparatide Nasal Spray
- Volunteers
- 350 people
- Sponsor
- Nastech Pharmaceutical Company, Inc.