Clinical trials: Osteoporosis
COPD,, Osteoporosis
Osteoporosis in Chronic Obstructive Pulmonary Disease (COPD)
Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of osteoporosis and fractures. Osteoporosis, however, may be equally as disabling as COPD, and may impair respiratory function even further if the…
- Trial name
- NCT01549028
- Testing
- mobile-based PR program.
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Osteoporosis, Sarcopenia
Does Potassium Bicarbonate Improve the Effect of Dietary Protein on Bone and Muscle?
The purpose of this study is to examine whether adding the basic salt potassium bicarbonate to the diet will have a positive effect on how dietary protein affects your bone and muscle.
- Trial name
- NCT00730184
- Testing
- potassium bicarbonate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Tufts University
Osteoporosis, Post-Menopausal
Combination Osteogenic Therapy in Established Osteoporosis
This study is designed to determine if combining parathyroid (PTH 1-34) with fluoride (MFPSR) therapy in a cyclic treatment regimen will: (1) produce a greater increase in bone density of the spine than would be produced by…
- Trial name
- NCT00018447
- Testing
- PTH 1-34, MFPSR-fluoride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Osteoporosis, Osteopenia
Encouraging Calcium Absorption and Bone Formation During Early Puberty
Increasing bone mass during puberty can ultimately decrease the risk of developing osteoporosis, which causes bones to weaken and break more easily later in life.
- Trial name
- NCT00022867
- Testing
- Nondigestible oligosaccharide (NDO)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Osteoporosis
Osteoporosis Research Registry
The aim of this research registry is to collect information on individuals with osteoporosis, those with risk factors for osteoporosis, and comparative healthy controls.
- Trial name
- NCT01223300
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Primary Hyperparathyroidism, Osteoporosis
Osteoporosis in Primary Hyperparathyroidism
Investigators will prospectively include 40 postmenopausal women with secondary osteoporosis due to primary hyperparathyroidism who have refused surgery.
- Trial name
- NCT04085419
- Testing
- Denosumab 60 MG/ML Prefilled Syringe [Prolia], Zoledronic Acid
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- University Medical Centre Ljubljana
Type 2 Diabetes Mellitus, Menopause
Effect of Anti-diabetic Drugs on Bone Metabolism and Glycemic Variability
This is a Monocentric, Prospective, Randomized, Open-label, Comparative, Phase IV Study, to compare the effects of Vildagliptin and Gliclazide MR on Markers of Bone Remodeling, Bone Mineral Density and Glycemic Variability in…
- Conditions
- Type 2 Diabetes Mellitus, Menopause, Osteoporosis, Osteopenia
- Trial name
- BoneGlyc (NCT01679899)
- Testing
- Vildagliptin, Gliclazide MR
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Centro de Diabetes Curitiba Ltda
Distal Radius Fractures, Poor Bone Quality
The Influence of Local Bone Status on Complications After Surgical Treatment of Distal Radius Fractures
The purpose of this study is to evaluate if poor bone quality increases the risk of specific types of treatment complications in patients with distal radius fractures treated with open reduction and Locking Compression…
- Conditions
- Distal Radius Fractures, Poor Bone Quality, Treatment Complications
- Trial name
- NCT01144208
- Where
- 11 sites in United States, Austria and 4 more
- Volunteers
- 244 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Osteopenia, Osteoporosis, Sarcopenia
Functional and Metabolic Effects of Fonte Fausta® Water on Bone and Muscle Health in Osteoporotic Patients
This clinical study investigates the effects of Fonte Fausta® water on bone and muscle metabolism, as well as quality of life, in patients with osteoporosis or osteopenia, with or without sarcopenia.
- Trial name
- FOCUS (NCT06851676)
- Testing
- water supplemented by calcium
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ANTIMO
Menopausal Osteoporosis
Effect of VSL#3 on Bone Mineral Density in Postmenopausal Women
Osteoporosis has a devastating impact on quality of life of postmenopausal women, and is a significant cause of disability and morbidity.
- Trial name
- ProBoneVSL (NCT03165747)
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Osteoporotic Fractures, Spinal Fractures
Build Better Bones With Exercise
The long-term goal of our research team is to conduct a large multicentre study to evaluate whether tailored home exercise can prevent fractures in high-risk individuals.
- Trial name
- B3E (NCT01761084)
- Testing
- Exercise and behaviour change strategies
- Where
- Canada
- Volunteers
- 141 people
- Sponsor
- University of Waterloo
Osteoporosis, Postmenopausal, Bone Density, Low
The Effect of the Probiotic Strains on Bone Mineral Density in Postmenopausal Women
Osteoporosis is a systemic condition characterized by low bone mass and altered bone tissue microarchitecture, with the resulting greater bone fragility leading to fractures.
- Trial name
- NCT06375668
- Testing
- Probiotic
- Where
- 3 sites in Poland
- Volunteers
- 170 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Osteoporosis, Postmenopausal
Denosumab Biosimilar Injection in Post Menopausal Women With Osteoporosis
Denosumab of Intas is biosimilar denosumab candidate under development by Intas Pharmaceutical Limited (Biopharma Division). Denosumab of Intas is already approved by Indian drug licensing authority- Drug Controller General…
- Trial name
- NCT05419427
- Testing
- Denosumab, Denosumab-Ref
- Where
- India
- Volunteers
- 552 people
- Sponsor
- Lambda Therapeutic Research Ltd.
Osteoporosis
Vitamin D Osteoporosis Long-Term Care Study
The research question is, does a multifaceted, multidisciplinary intervention including small groups, chart audits and point of care tools, increase the number of people receiving optimal vitamin D therapy in the long term care…
- Trial name
- ViDOS (NCT01398527)
- Testing
- Educ sessions & LTC Osteoporosis toolkit
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McMaster University
Sarcopenia, Chronic Kidney Diseases
Sarcopenia, Fall and Osteoporosis in Chronic Kidney Disease
This study is a cross-sectional study that wishes to investigate whether there is an increased incidence of sarcopenia in patients with chronic kidney disease compared to the Danish background population.
- Conditions
- Sarcopenia, Chronic Kidney Diseases, Osteoporosis
- Trial name
- NCT04515342
- Testing
- DXA, Muscle strength and function assessment, Blood samples
- Where
- 2 sites in Denmark
- Volunteers
- 140 people
- Sponsor
- Herlev Hospital
Osteoarthritis, Knee, Prosthesis User
Characteristics of Marrow Fatty Cells in the Ageing of Bone and Joints, Osteoarthritis and Osteoporosis
Obesity and other associated complications promote the development and the progression of osteoarthritis. The subcutaneous and abdominal fat release several factors that alter bone and the cartilage.
- Trial name
- MEDADIPO (NCT03678831)
- Testing
- tissue
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Lille
Osteopenia, Osteoporosis
Once Weekly Parathyroid Hormone for Osteoporosis
Daily parathyroid hormone (PTH) is approved by the FDA for the treatment of osteoporosis. This study will evaluate the safety and effectiveness of PTH when given once a week.
- Trial name
- NCT00065637
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Osteoporosis
A Direct-to-patient Intervention to Increase Rates of Osteoporosis Care
The purpose of this study is to conduct a randomized trial of a tailored intervention designed to provide personalized feedback regarding patients' risk of subsequent fractures, customized information regarding osteoporosis care…
- Trial name
- APROPOS (NCT01907269)
- Testing
- Video-based Intervention
- Where
- 7 sites in United States
- Volunteers
- 2,684 people
- Sponsor
- University of Alabama at Birmingham
Liver Diseases, Transplant-Related Disorder
Liver Transplantation: Skeletal Effects
Fifty patients awaiting liver transplantation and 50 age and gender matched control subjects with normal liver function will be included in the study.
- Conditions
- Liver Diseases, Transplant-Related Disorder, Osteoporosis
- Trial name
- NCT03399227
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Osteoporosis, Postmenopausal
Parameters of Exercise to Prevent Osteoporosis
The principal goal of this study is to determine parameters of walking in terms of peak mechanical vertical force, bout duration, and bout spacing that can preserve or increase bone mineral density (BMD) in postmenopausal women.
- Trial name
- OSTEOPOROSISEX (NCT04063813)
- Testing
- Experimental: 40 minute up trial, Experimental: 40 minute down trial, Experimental: Two 20 minute up trials
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan