Clinical trials: Osteoporosis Fracture
Osteoporotic Fracture of Vertebra
Vertebroplasty and Kyphoplasty in Osteoporotic Vertebral Body Fractures.
Vertebral body fractures are a major health care problem in all countries with incidence 1.4%. They are a common cause of severe debilitating pain, with consequent deteriorated quality of life, physical function and psychosocial…
- Trial name
- NCT03682328
- Testing
- vertebroplasty, kyphoplaty
- Volunteers
- 23 people
- Sponsor
- Assiut University
Osteoporosis, Proximal Femur Fracture
In Vivo Hip Fracture Discrimination With Quantitative Computed Tomography (QCT)
Numerous geometric and bone mineral density (BMD) parameters can be derived from quantitative computed tomography (QCT) images of the proximal femur analyzed using dedicated software.
- Trial name
- FEMFRACT (NCT01035177)
- Where
- France
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoporosis and Fracture Risk in Pregnant Women
Pregnancy and Lactation- Associated Osteoporosis
Pregnancy-Associated Osteoporosis is a condition characterized by loss of bone mass and fragility fractures during pregnancy or breastfeeding, often due to the increased calcium request from fetus.
- Trial name
- POI (NCT07031557)
- Testing
- EchoStation Implementing REMS Technology, Nutritional and Fracture Risk Assessment Questionnaires
- Where
- Italy
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- Parma University Hospital
Osteoporotic Fracture of Vertebra
Percutaneous Vertebral-disc Plasty for Thoracolumbar Very Severe Osteoporotic Vertebral Compression Fractures
Purpose: To compare the clinical outcomes and radiological parameters of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing percutaneous vertebral-disc plasty (PVDP) for back pain, segmental…
- Trial name
- NCT05519332
- Testing
- percutaneous vertebral-disc plasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiawei Jiang
Beta Blocker Toxicity
Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis
Clinical study evaluating selective or nonselective beta blockers use and fracture risk in patients with primary osteoporosis
- Trial name
- NCT04704947
- Testing
- nonselective beta blocker, cardio-selective beta blocker group, alendronate sodium
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sherief Abd-Elsalam
Juvenile Osteoporosis, Low Bone Density
Alendronate in Juvenile Osteoporosis
The investigators earlier have shown that treatment of patients with juvenile osteoporosis with alendronate (Fosamax) for 12 months increased the bone density without side effects.
- Conditions
- Juvenile Osteoporosis, Low Bone Density, Fractures
- Trial name
- NCT00920075
- Testing
- Alendronate (Fosamax)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Medical University of South Carolina
Hip Fracture, Malnutrition
Nutritional Intervention in Hip Fracture Patients
Hip fractures are highly prevalent and are expected to increase due to the ageing population. Malnutrition is often present in these patients and is associated with prolonged convalescence, lower mobility, lower mental function…
- Trial name
- NCT00523575
- Testing
- Cubitan
- Where
- 3 sites in Netherlands
- Volunteers
- 210 people
- Sponsor
- Maastricht University Medical Center
Compression Fracture of Vertebral Body, Osteoporosis
Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs
The study objective is to collect and report 12-month outcomes pertaining to activities of daily living, quality of life, and safety parameters in a Medicare population to be treated with balloon kyphoplasty in the treatment of…
- Conditions
- Compression Fracture of Vertebral Body, Osteoporosis, Cancer
- Trial name
- EVOLVE (NCT01871519)
- Testing
- Balloon kyphoplasty
- Where
- 25 sites in United States
- Volunteers
- 354 people
- Sponsor
- Medtronic Spinal and Biologics
Fractures Related to Skeleton Fragility
Fracture Prediction by Opportunistic Screening for Osteoporosis
Fractures related to skeleton fragility (i.e. osteoporotic fractures) represent a growing health problem, as the life expectancy and thus the number of frail elderly subjects is increasing.
- Trial name
- OPPORTOS (NCT03570177)
- Where
- France
- Volunteers
- 173,720 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Compression Fracture
Comparison of Treatments of Osteoporotic Compression Fracture Using Rigid Brace, Soft Brace, and no Brace
The treatment outcomes in the treatment without brace would be non-inferior to those in use of rigid or soft brace.
- Trial name
- NCT02049931
- Testing
- No brace treatment, Rigid brace, Soft brace
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Osteoporosis
Safety and Efficacy of Alendronate (Fosamax) in Children With Osteoporosis
We have previously evaluated the safety and efficacy of Alendronate in 10 patients with juvenile osteoporosis during a 12-month clinical trial.
- Trial name
- NCT00259857
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Osteoporosis, Hyperkyphosis
Nordic Walking for Individuals With Osteoporosis, Vertebral Fracture or Hyperkyphosis
Nordic walking is currently offered by a number of health care practitioners as a form of exercise therapy for older adults at risk of fracture.
- Conditions
- Osteoporosis, Hyperkyphosis, Vertebral Fracture
- Trial name
- NCT03885466
- Testing
- Nordic Walking exercise
- Where
- Canada
- Volunteers
- 117 people
- Sponsor
- University of Saskatchewan
Osteoporosis, Postmenopausal
Efficacy and Safety of MW031 in PMO Subjects
This study is a multicenter, randomized, double-blinded, placebo-controlled Phase III clinical study to evaluate the clinical efficacy and safety of MW031 in Chinese postmenopausal osteoporotic subjects with increased bone…
- Trial name
- NCT05215977
- Testing
- MW031
- Where
- China
- Volunteers
- 448 people
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
Osteoporosis, Fracture Risk Assessment
New Tools for Assessing Fracture Risk
The goal of this study is to determine whether two new, non-X-ray techniques can discriminate between high-energy fractures of normal bone (trauma) and low-energy fractures (fragility) of osteoporotic bone.
- Trial name
- NCT02436356
- Testing
- Osteoprobe-Reference Point Indentation (RPI), Dual-energy X-ray absorptiometry (DXA) Scans, MRI
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Fragility Fractures of the Pelvis (FFP), Osteoporosis
Robot Assisted Minimally Invasive Treatment Versus Conventional Surgery for FFP3-4 Fragility Fractures of the Pelvis in Elderly Patients
This prospective randomized controlled trial aims to compare the efficacy and safety of robot assisted minimally invasive treatment versus conventional surgery in elderly patients with FFP3-4 fragility fractures of the pelvis.
- Trial name
- NCT07639619
- Testing
- Robot Assisted Minimally Invasive Fixation, Conventional Open Fixation
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Junbo Liang
Osteoporosis
HIV UPBEAT: Understanding the Pathology of Bone Disease in HIV-infected Patients.
Despite the prevalence of osteopenia and osteoporosis in the HIV positive population, relatively little is known about the underlying pathology.
- Trial name
- UPBEAT (NCT01778361)
- Where
- Ireland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Osteoporosis, Postmenopausal, Vertebral Fracture
Comparation of Treatment Strategies for OVF: Teriparatide Injection and PVP
This study aimed to compare teriparatide treatments and PVPs, focusing on its effects on life qualities and effect/coast ratio and evaluate which method is better for patients.
- Conditions
- Osteoporosis, Postmenopausal, Vertebral Fracture, Quality of Life
- Trial name
- NCT03692143
- Testing
- Teriparatide, PVP, Alendronate
- Volunteers
- 90 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Osteoporotic Vertebral Compression Fracture
The Comparative Study About the Effect of Vertebral Body Decompression Procedure
The purpose of this study is to compare the treatment efficacy between vertebral body decompression procedure and conservative treatment with non-inferiority design
- Trial name
- NCT02902250
- Testing
- Decompression, Conservative Treatment
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Osteoporosis
A Randomized Controlled Trial of a Bone Density Decision Aide
This research study is being conducted to determine if a modified bone mineral density (BMD) test report that contains additional fracture risk information will be a useful physician decision aide in selecting patients for…
- Trial name
- NCT00285168
- Testing
- Bone Density Decision Aide
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Osteoporosis, Low-energy Trauma Fracture
3D Imaging of the Hip Using DXA
The study aims to determine the efficacy and best methods for predicting hip fractures and diagnosing post-menopausal osteoporosis using three dimensional structural engineering models (SEMs) of proximal femoral bone produced…
- Trial name
- 3DScans (NCT00666640)
- Testing
- DXA scan of hip, CT scan of hip
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust