Clinical trials: Osteoporosis Fracture
Osteoporotic Fracture of Vertebra
Percutaneous Vertebral-disc Plasty for Thoracolumbar Very Severe Osteoporotic Vertebral Compression Fractures
Purpose: To compare the clinical outcomes and radiological parameters of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing percutaneous vertebral-disc plasty (PVDP) for back pain, segmental…
- Trial name
- NCT05519332
- Testing
- percutaneous vertebral-disc plasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiawei Jiang
Osteoporosis, Osteoporotic Fractures
Osteoporosis and Knee Insufficiency Fracture
Osteoporosis is a systemic bone disease characterized by low bone mass and microarchitectural deterioration of bone tissue with consequent bone fragility and susceptibility to fracture.
- Conditions
- Osteoporosis, Osteoporotic Fractures, Osteonecrosis
- Trial name
- NCT02332681
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- University of Sao Paulo General Hospital
Vertebral Fracture, Osteonecrosis
Vertebral Fracture and Osteonecrosis Associated With High-dose Glucocorticoid
Osteoporotic vertebral fracture (VF) and osteonecrosis of the femoral head (OFH) are major concerns in patients with systemic rheumatic diseases treated with high-dose glucocorticoids (GCs).
- Conditions
- Vertebral Fracture, Osteonecrosis, Rheumatic Diseases
- Trial name
- NCT00679978
- Volunteers
- 60 people
- Sponsor
- Saitama Medical University
Hip Fractures, Osteoporotic Fractures
Fixation Methods of Basicervical Fractures
This prospective, randomized study included patients aged over 65 years with basicervical fracture of femur from January 2016 to January 2018.
- Trial name
- NCT04240743
- Testing
- cephalomedullary nail, sliding hip screw
- Volunteers
- 64 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Osteoporosis in Post-menopausal Women, Vertebral Body Fractures
Effect of Muscle Stiffness on Vertebral Fractures in Women Over 60
This study aims to assess the quality of lumbar and abdominal core muscles through elastography and evaluate its impact on vertebral fracture risk.
- Conditions
- Osteoporosis in Post-menopausal Women, Vertebral Body Fractures, Balance, Postural
- Trial name
- NCT06687889
- Testing
- Elastography Measurements, Bone Mineral Density Measurement (DEXA), Berg balance scale
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Osteoporotic Vertebral Compression Fracture
The Comparative Study About the Effect of Vertebral Body Decompression Procedure
The purpose of this study is to compare the treatment efficacy between vertebral body decompression procedure and conservative treatment with non-inferiority design
- Trial name
- NCT02902250
- Testing
- Decompression, Conservative Treatment
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Osteoporosis
Analgesic Effects of the Gastrolith, in Osteoporotic Patients Suffering From Recent Skeletal Pain Caused by Vertebral Fractures
This study aims to evaluate the safety and analgesic effect (efficacy) of Gastrolith powder (GASP) on skeletal pain caused by osteoporotic vertebral compression fractures (OVCF) versus placebo, primarily as assessed by the…
- Trial name
- NCT01482858
- Testing
- Gastrolith
- Where
- 5 sites in Israel
- Sponsor
- Amorphical Ltd.
Hip Fractures
Vibration Therapy as an Intervention for Enhancing Trochanteric Hip Fracture Healing in Elderly Patients
Currently, there are approximately 300,000 hip fractures per year in the US with a mortality rate of 20% within 1 year. In Hong Kong, around 6,000 hip fractures occur yearly with costs approximately 52 million USD, and these…
- Trial name
- NCT04063891
- Testing
- Low-magnitude high-frequency vibration (LMHFV)
- Where
- Hong Kong
- Volunteers
- 83 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Osteoporosis, Vertebral Fracture
Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures
Postmenopausal women with vertebral fractures (VFs) represent an important target for secondary fracture prevention, but few of these patients come for clinical attention.
- Trial name
- COSHIBA (NCT00463905)
- Testing
- Clinical assessment +/- radiography
- Where
- United Kingdom
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Osteoporosis, Postmenopausal
Impact of Oral Ibandronate 150 mg Monthly on Structural Properties of Bone in Postmenopausal Osteoporosis (SPIMOS-3D)
Efficacy: To investigate changes of structural bone properties in vivo using 3DpQCT ("Xtreme" CT, Scanco) in monthly oral ibandronate therapy for women with postmenopausal osteoporosis.
- Trial name
- NCT00271713
- Testing
- ibandronate, calcium and vitamin D
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Osteoporosis, Accidental Falls
The Effect of Digital Education for Osteoporosis Patients on Fracture Risk and Related Health Outcomes.
A digital education for osteoporosis patients (DEOP) has been developed and tested on patients in Region Vastra Gotaland, Sweden.
- Conditions
- Osteoporosis, Accidental Falls, Fractures, Bone, Patient Reported Outcome Measures
- Trial name
- NCT06603545
- Testing
- Digital education for osteoporosis patients
- Volunteers
- 2,640 people
- Sponsor
- Sahlgrenska University Hospital
Stroke, Anoxia
Bone Loss, Fractures, and Management of Bone Health in People With Stroke in Managed Rehabilitation Settings
The purpose of the study is to evaluate the state of bone health of brain injury patients being seen within a rehabilitation setting.
- Conditions
- Stroke, Anoxia, Brain Injury
- Trial name
- NCT00462683
- Where
- 2 sites in United States
- Volunteers
- 87 people
- Sponsor
- Northwestern University
Severe Osteoporosis
Phase 2a Study on Intravenous Infusion of Autologous Osteoblastic Cells in Severe Osteoporosis
Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a subsequent increase in bone fragility and susceptibility to fracture.
- Trial name
- NCT02061995
- Testing
- PREOB® Intravenous Infusion
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Erasme University Hospital
Aging, Sarcopenia
A Prospective Cohort Study of Aged People for Chronic Diseases
This study is a hospital-based, prospective cohort study to elucidate the predictive factors including muscle and fat mass for chronic diseases and mortality in elderly persons aged 60 years and older.
- Trial name
- HAPPY (NCT02640872)
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Osteoporosis, Osteopenia
Effects of OsteoStrong vs. Individually Adapted and Combined Training on Bone Health
The aim of this clinical trial is to investigate the effect of the OsteoStrong training method and the Individually Adapted and Combined Training on the bone health of older women with high fracture risk.
- Conditions
- Osteoporosis, Osteopenia, Bone Density, Low, Bone Loss
- Trial name
- NCT05721014
- Testing
- OsteoStrong, Individually Adapted and Combined Physical Training
- Where
- Sweden
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pathologic Fracture of the Vertebra Due to Osteoporosis
Clinical Evaluation of the Crosstrees Pod™ in the Treatment of Pathologic Fracture of the Vertebral Body (Levels T4 - L5) in Adult Patients
The clinical trial is being conducted to evaluate the performance of the Crosstrees System in reducing pain and decreasing the risk of cement leakage associated with vertebroplasty and kyphoplasty.
- Trial name
- NCT00933036
- Testing
- Crosstrees Pod system for PVA
- Where
- 9 sites in United States
- Volunteers
- 135 people
- Sponsor
- Crosstrees Medical Inc.
Bone Disease, Metabolic, Osteopenia
Electromagnetic Treatment For Bone Loss After Forearm Fracture
This study will determine the usefulness of pulsing electromagnetic field (PEMF) technology to reverse or reduce the bone loss (osteopenia) that occurs in the forearm after fracture or surgery.
- Conditions
- Bone Disease, Metabolic, Osteopenia, Osteoporosis, Post-Traumatic
- Trial name
- NCT00067834
- Testing
- Pulsing electromagnetic field (PEMF)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoporosis
Safety and Efficacy of Alendronate (Fosamax) in Children With Osteoporosis
We have previously evaluated the safety and efficacy of Alendronate in 10 patients with juvenile osteoporosis during a 12-month clinical trial.
- Trial name
- NCT00259857
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Type 2 Diabetes, Osteoporosis
Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes
The DIACTIVE study is a randomized controlled trial with a 5- year follow-up designed to evaluate the impact of comprehensive screening and multicomponent interventions on fall prevention, bone health, nerve function and…
- Conditions
- Type 2 Diabetes, Osteoporosis, Diabetic Neuropathies, Fall Prevention
- Trial name
- DiaACTIVE (NCT06745544)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Osteoporosis
Secondary Prevention of Osteoporosis
The purpose of this study is to develop and implement an evidence based protocol for the secondary prevention of osteoporotic fractures and falls, and to determine how compliance with this intervention improves muscle strength…
- Trial name
- NCT00421343
- Testing
- alendronate with cholecalciferol, calcium carbonate with cholecalciferol, Falls prevention measures
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Hebrew SeniorLife