Clinical trials: Osteoporosis Postmenopausal
Osteoporosis, Postmenopausal
Effect of Laser Acupuncture on Forearm Bone Mineral Density and Wrist Pain in Osteoporotic Postmenopausal Women
Sixty-eight postmenopausal women diagnosed with osteoporosis aged between 50 and 60 years were randomly allocated to one of two equal sets. The drug treatment group received calcium and vitamin D3 supplement daily for 12 weeks.
- Trial name
- NCT05559619
- Testing
- Calcium carbonate, Vitamin D3, laser acupuncture therapy
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Osteoporosis, Postmenopausal
Comparison Medications in the Treatment of Postmenopausal Women With Osteoporosis
To compare in postmenopausal women with established osteoporosis the effect of treatment with teriparatide 20 micrograms/day subcutaneous with the effect of salmon calcitonin 100 IU/day subcutaneous on change in lumbar spine BMD.
- Trial name
- NCT00542984
- Testing
- teriparatide 20 micrograms/day subcutaneous, salmon calcitonin 100 IU/day subcutaneous
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Eli Lilly and Company
Postmenopausal Osteoporosis
A Study of Quarterly Intravenous Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis.
This single arm study will assess the efficacy and safety of quarterly intravenous Bonviva in women with post-menopausal osteoporosis. All patients will receive Bonviva 3mg i.v. every 3 months.
- Trial name
- NCT00493532
- Testing
- ibandronate [Bonviva/Boniva]
- Where
- 14 sites in Taiwan
- Sponsor
- Hoffmann-La Roche
Osteoporosis, Postmenopausal, Osteopenia
Influence of Alfacalcidol on Falls in Osteopenic/Osteoporotic Postmenopausal Women (ALFA Study)
The purpose of this study is to evaluate the effect of alfacalcidol 1 µg daily on the number of fallers in postmenopausal, alendronate-treated, osteopenic or osteoporotic women.
- Conditions
- Osteoporosis, Postmenopausal, Osteopenia, Falls
- Trial name
- NCT00168909
- Testing
- alfacalcidol
- Where
- 2 sites in Germany
- Volunteers
- 282 people
- Sponsor
- Charite University, Berlin, Germany
Osteoporosis, Postmenopausal Osteoporosis
Efficacy and Safety of Odanacatib in Postmenopausal Women Previously Treated With Alendronate (MK-0822-050)
This study will evaluate the therapeutic effects and safety of odanacatib on bone mineral density in osteoporotic postmenopausal women who were previously treated with alendronate.
- Trial name
- NCT01552122
- Testing
- Odanacatib, Alendronate, Cholecalciferol (Vitamin D3)
- Sponsor
- Merck Sharp & Dohme LLC
Primary Hyperparathyroidism, Bone Diseases, Metabolic
Radius Loading in Primary Hyperparathyroidism
The purpose of the study is to determine the effect of forearm exercise on forearm bone density in post-menopausal women with or without primary hyperparathyroidism.
- Conditions
- Primary Hyperparathyroidism, Bone Diseases, Metabolic, Osteoporosis, Postmenopausal, Bone Loss, Postmenopausal
- Trial name
- NCT01571843
- Testing
- Forearm exercise program, Walking program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cardiovascular Diseases, Osteoporosis
A Study on the Impact of Calcium on Woman's Vascular Health
The overarching aim of this randomized clinical trial is to estimate the effect of dietary intake of calcium as compared to supplemental calcium on the vascular system and markers of vascular and bone health in postmenopausal…
- Trial name
- NCT01731340
- Testing
- Calcium Citrate, Low Dietary Calcium, High Dietary Calcium
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Postmenopausal Osteoporosis
StrAtegies For Zoledronic Acid Post-dEnosumab Discontinuation in Postmenopausal oSTeoporosis
Denosumab (Dmab) is a treatment for postmenopausal osteoporosis. However, its withdrawal is associated with a rebound phenomenon associated with an unexpected increased risk of vertebral fractures.
- Trial name
- SAFEST (NCT06767150)
- Testing
- a second infusion of ZOL when crosslaps levels reach 300 pg/mL, a rescue second infusion at month-12 (standard traitment)
- Where
- 17 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Toulouse
Osteoporosis
Compliance and Persistence With Osteoporosis Treatment and Attitude Towards Future Therapy Among Post-menopausal Israeli Women During Drug Treatment or Drug Holiday
The purpose of the study is to provide information about the rate of response and persistence to drug therapies for osteoporosis.
- Trial name
- CONTINUITY (NCT01854086)
- Testing
- Questionnaires about compliance and persistence with bisphosphonates treatment
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Meir Medical Center
Osteopenia or Osteoporosis
Effect of Consumption of Supplements and Enriched Olive Paste on Bone Metabolism Indices
It was a prospective randomized controlled trial. A sample of 115 apparently healthy post-menopausal women(45 -75 years of age) randomized into four groups and received supplements of Ca, Vitamin D and Mg with or without enriched…
- Trial name
- Osteoporosis (NCT06135831)
- Testing
- Functional olive paste, Calciovitmag (CDCaMg), Phosporovitmag (PDCaMg)
- Where
- Greece
- Volunteers
- 115 people
- Sponsor
- University of the Aegean
Osteoporosis, Osteopenia
Texture Analysis for Postmenopausal Osteoporosis
The purpose of this study is to determine if a new test for osteoporosis can be useful in monitoring treatment. We are studying a new method for examining the quality of bone by an experimental method of computerized analysis of…
- Trial name
- NCT00145977
- Testing
- Alendronate, Calcium Citrate, Vitamin D
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Chicago
Osteoporosis, Postmenopausal
Comparison of Raloxifene Hydrochloride and Placebo in the Treatment of Postmenopausal Women With Osteoporosis
To study the effect of long-term treatment with raloxifene, compared with placebo, on the rate of new vertebral fractures in osteoporotic postmenopausal women with and without existing vertebral fractures.
- Trial name
- MORE (NCT00670319)
- Testing
- Raloxifene HCL
- Where
- 25 sites in United States, Argentina and 23 more
- Volunteers
- 7,705 people
- Sponsor
- Eli Lilly and Company
Hypovitaminosis D, Osteoporosis, Postmenopausal
Effect of Vitamin D and Denosumab on Bone Remodelling in Women With Postmenopausal Osteoporosis
Denosumab is a monoclonal antibody against RANKL ligand, which is used as an alternative treatment for osteoporosis in patients who have a poor response to first-line antiresorptive therapy.
- Conditions
- Hypovitaminosis D, Osteoporosis, Postmenopausal, Menopause
- Trial name
- NCT05372224
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 55 people
- Sponsor
- Hospital Regional 1o de Octubre
Osteoporosis, Postmenopausal
Parameters of Exercise to Prevent Osteoporosis
The principal goal of this study is to determine parameters of walking in terms of peak mechanical vertical force, bout duration, and bout spacing that can preserve or increase bone mineral density (BMD) in postmenopausal women.
- Trial name
- OSTEOPOROSISEX (NCT04063813)
- Testing
- Experimental: 40 minute up trial, Experimental: 40 minute down trial, Experimental: Two 20 minute up trials
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Endometrial Hyperplasia, Osteoporosis
Study Evaluating Safety and Efficacy of Bazedoxifene/Conjugated Estrogens Combinations in Postmenopausal Women
The purpose of this study is to determine whether bazedoxifene/conjugated estrogens combinations are effective for the prevention of endometrial hyperplasia and for the prevention of osteoporosis in postmenopausal women.
- Trial name
- NCT00675688
- Testing
- Bazedoxifene/Conjugate Estrogens (CE), Raloxifene
- Volunteers
- 3,544 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Obesity, Osteoporosis
Bone Metabolism After Bariatric Surgery
The purpose and objective of this study is to determine the changes in bone metabolism after bariatric surgery in postmenopausal women.
- Trial name
- NCT01824797
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Duke University
Osteoporosis
The Prevention of Osteoporosis in Premenopausal and Newly Postmenopausal (Up to 8 Years) Women With Breast Cancer Following Chemotherapy (REBBeCA Study)
The purpose of this study is to evaluate the effectiveness of once weekly risedronate in the prevention and treatment of bone loss in premenopausal and newly menopausal women with breast cancer who have received chemotherapy.
- Trial name
- NCT00118508
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Pittsburgh
Osteoporosis
A Study to Evaluate Oral Salmon Calcitonin in the Treatment of Osteoporosis in Postmenopausal Women Taking Calcium and Vitamin D
The purpose of this Phase III study is to evaluate the efficacy and safety of oral salmon calcitonin in the treatment of patients with osteoporosis
- Trial name
- NCT00525798
- Testing
- SMC021 Oral calcitonin
- Where
- 16 sites in United States, Brazil and 10 more
- Volunteers
- 4,665 people
- Sponsor
- Nordic Bioscience A/S
Osteoporosis
A Study to Test Once-Weekly Doses of Odanacatib (MK0822) on Healthy Adult Females (0822-005)(COMPLETED)
This study will assess the safety, tolerability, PK, and PD of a once weekly dose of MK0822 in healthy postmenopausal women.
- Trial name
- NCT00770159
- Testing
- odanacatib
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Osteoporosis, Postmenopausal
ValoRization of Dairy Sidestreams to Fight Calcium dEficits iN Postmenopausal Women
The primary objective of this study is to investigate the effects of 12-months supplementation with calcium-enriched permeate, taken alone or in conjunction with inulin, on changes in markers of bone formation and resorption and…
- Trial name
- RENEW (NCT04836637)
- Testing
- Maltodextrin, Calcium-carbonate, Calcium-enriched permeate
- Where
- 2 sites in Denmark
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen