Clinical trials: Osteosynthesis
Flail Chest
MatrixRIB Implants for Surgical Stabilization of Flail Chest Injuries: A Registry
The purpose of this observational study is to document the treatment of serial rib fractures with MatrixRIB implants in a registry.
- Trial name
- MatrixRIB (NCT00810251)
- Testing
- MatrixRIB (FDA Approval # K081623)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Legacy Biomechanics Laboratory
Hand Fractures
Repair of Extra-articular Fractures of the Metacarpals and First Phalanges of the Long Fingers
The goal of this randomized controlled trial is to compare the effectiveness, complications, and cost-effectiveness of three surgical techniques (intramedullary screw fixation, locked plating, and percutaneous pinning) for…
- Trial name
- FinXger (NCT07186829)
- Testing
- Percutaneous pinning, Locked plate, Intramedullary screw
- Where
- France
- Volunteers
- 111 people
- Sponsor
- University Hospital, Montpellier
Fragility Ankle Fractures and Complex Distal Tibial Fractures
Tibio-talo-calcaneal Fusion by Hindfoot Nail Versus Open Reduction and Internal Fixation in Treatment of Complex Fractures Distal Tibial and Fragility Ankle Fractures in Elderly
Tibiotalar calcaneal fusion by hindfoot nail Vs open reduction and internal fixation in treatment of complex distal tibial fractures and ankle fragility ankle fractures in elderly
- Trial name
- NCT06709365
- Testing
- Tibiotalar calcaneal fusion by hindfoot
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Mandibular Class Iv Fractures
Patient-Specific Guides vs. Classical Workflow in Class IV Mandibular Fracture Fixation
This study aims to overcome the limitations of current, standard approach of mandibular fracture reduction and fixation including improper alignment of segments, malocclusion, nerve affections and related teeth roots injury.
- Trial name
- NCT07153354
- Testing
- patient-specific screw holes locating surgical guide and pre-bent plates, 2 titanium per-bent mini plates
- Volunteers
- 20 people
- Sponsor
- Mohamed abdelsalam Gaber elkhouly
Undisplaced Fracture, Femoral Neck Fractures
Arthroplasty Versus Internal Fixation for Undisplaced Femoral Neck Fracture
This is the world's first national orthopedic randomized controlled trial (RCT) involving 19 out of 21 departments in Denmark. Each year, 7,000 patients suffer a hip fracture.
- Conditions
- Undisplaced Fracture, Femoral Neck Fractures, Internal Fixation; Complications, Arthroplasty Complications
- Trial name
- SENSE (NCT04075461)
- Testing
- Arthroplasty, Internal fixation
- Where
- 19 sites in Denmark
- Volunteers
- 330 people
- Sponsor
- University of Southern Denmark
Femoral Neck Fractures
Comparison Study of 3-4-screws-internal Fixation With Multi-screw-system Targon FN for Femoral Neck Fracture
The purpose of this study is to compare between two methods of internal fixation, the 3-4 parallel screws or the Targon FN implant in gardens type 1-2 or Pauwels type 1-2 femoral neck fractures in terms of the outcomes and…
- Trial name
- NCT00829725
- Testing
- screws-internal fixation, TARGON FN
- Where
- 3 sites in Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Tibial Fractures, Fibula Fracture
Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation
Palmitoylethanolamide (PEA), a non-psychoactive cannabis compound derived from peanuts, egg yolks, and soybeans, is an Endogenous FA Amide produced in the body as a biological response and a repair mechanism in chronic…
- Conditions
- Tibial Fractures, Fibula Fracture, Knee Fracture
- Trial name
- NCT05317676
- Testing
- Palmitoylethanolamide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified
A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements
This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children…
- Conditions
- Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation
- Trial name
- NCT07552766
- Testing
- Lidocaine Infusion, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Nemours Children's Clinic
Distal Femur Fractures
Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation
The purpose of this study is to evaluate the performance of Dynamic Locking Screws (DLS) used to stabilize the shaft component of distal femur fractures in comparison to standard locking screws (SLS).
- Trial name
- NCT01693367
- Testing
- DLS 5.0 (Dynamic locking screws), SLS (Standard locking screw)
- Where
- 12 sites in United States, Austria and 2 more
- Volunteers
- 5 people
- Sponsor
- AO Innovation Translation Center
Distal Radius Fractures, Mechanical Complication of Internal Rod Fixation Device
Results Of Usage Of Bridging Plate In Multi-fragmentary Distal Radius Fracture
using a plate as a distraction method bridging the comminution to restore anatomical parameters to treat comminuted distal radius fracture follow-up functional outcomes of the wrist after metal removal
- Conditions
- Distal Radius Fractures, Mechanical Complication of Internal Rod Fixation Device, Internal Fixation; Complications
- Trial name
- NCT06723483
- Testing
- Distraction Plate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mina Hany Moris Zakhary
Humeral Fracture
Treatment of Humeral Fractures With Long PHILOS Plates Using a Modified Technique and Approach Avoids Radial Nerve Palsy
Radial paralysis is a well-known complication of plate osteosynthesis on the humeral shaft. At the University Hospital Basel, these fractures have been treated in an adapted procedure with long PHILOS plates using a modified…
- Trial name
- NCT05256849
- Where
- Switzerland
- Volunteers
- 61 people
- Sponsor
- University Hospital, Basel, Switzerland
Magnesium-based, Bioresrobable Implants
MagnezixKids Study
The overall objective of the study is to describe the outcomes of osteosyn-thesis with magnesium based screws in children with a primary or second-ary (within 7 days from trauma) dislocated fracture of the Epicondyles ul-naris or…
- Conditions
- Magnesium-based, Bioresrobable Implants, Pediatric Elbow Fractures, Osteosynthesis
- Trial name
- NCT04571905
- Testing
- Osteosynthesis with resorbable Material
- Where
- Switzerland
- Volunteers
- 17 people
- Sponsor
- Thomas Krebs
Fracture Lower Leg, Diabetes
Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients
The goal of this clinical trial is to learn if taking an antibiotic pill for 7 days after surgery reduces the risk of wound infection in adults with poorly controlled diabetes who have surgery to fix a broken bone in the leg…
- Conditions
- Fracture Lower Leg, Diabetes, Fracture Fixation, Internal
- Trial name
- NCT07561541
- Testing
- Cefadroxil 500 mg Capsules, Clindamycin, Bactrim DS
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Radius; Fracture, Lower or Distal End
MIPO Versus Conventional Approach in Volar Locking Plate for Close Fractures Distal End Radius Under WALANT
The goal of this clinical trial is to compare the Minimally Invasive Plate Osteosynthesis (MIPO) approach with conventional methods in volar locking plate treatment for distal end radius fractures under the Wide Awake Local…
- Trial name
- NCT06260761
- Testing
- MIPO, Conventional
- Where
- Thailand
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Police General Hospital, Thailand
Glenoid; Fracture
Fixation of Glenoid Fractures
Scapula fractures are uncommon but make up 3-5% of all shoulder girdle injuries. Moreover, intraarticular glenoid fossa fractures represent only 1% of scapula fractures.
- Trial name
- NCT04070859
- Testing
- Internal Fixation of Glenoid Fractures
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Unstable Osteoporotic Vertebral Compression Fractures
RCT on the Efficacy and Safety of Minimally Invasive SAIF Technique vs Spinal Fixation in Unstable Osteoporotic Vertebral Fractures
Osteoporotic vertebral fractures (OVF) represent a significant cause of morbidity, mortality, decreased level of function and quality of life.
- Trial name
- SAIF (NCT07071870)
- Testing
- Stent-screw Assisted Internal Fixation (SAIF), Surgical stabilization
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- Eva Koetsier MD PhD
Femoral Neck Fracture
Total Hip Arthroplasty Compared to Internal Fixation for Displaced Intracapsular Fractures of the Femoral Neck
The primary aim of this study was to determine the Harris hip score as an evaluation of hip function, in mentally competent elderly patients (>65 years old) treated with either THR or IF, after contracting a displaced femoral…
- Trial name
- NCT01344772
- Testing
- Internal fixation, Total hip arthroplasty
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital
Acetabular Fractures
Pericapsular Nerve Group (PENG) Block on Postoperative Pain Management After Acetabular Fracture Fixation
The goal of this clinical trial is to find out whether a Pericapsular Nerve Group (PENG) block, a type of nerve block used to control pain, can reduce pain after surgery in adults with an acetabular (hip socket) fracture who are…
- Trial name
- NCT07765095
- Testing
- Pericapsular nerve group (PENG) block
- Where
- Puerto Rico
- Volunteers
- 56 people
- Sponsor
- University of Puerto Rico
Radius; Fracture, Lower or Distal End
Role of the Pronator Quadratus in Distal Radius Fractures
The skin, the bones, and most muscles received branches from the source arteries of at least two angiosomes, thus revealing one of the important anastomotic pathways by which the circulation is reconstituted in those cases where…
- Trial name
- NCT03371030
- Testing
- Pronatus quadratus reparation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Fracture of Patella
Clinical Outcome After Treatment of Patellar Fractures With Locking Plates
Depending on the fracture pattern of patellar fractures tension band wiring, interfragmentary screw fixation or combinations are common treatments.
- Trial name
- NCT02015975
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Diakoniekrankenhaus Friederikenstift