Clinical trials: Other Disease/Injury
Peripheral Nerve Disease, Peripheral Nerve Injury Lower Limb
Effect of Ankle-foot Orthoses on Balance Confidence
The patients at our Prosthetics and Orthotics Outpatient Clinic who have had an ankle-foot orthosis for at least one year will fill in the Activities-Specific Balance Confidence Scale (ABC Scale) for wearing the orthosis and for…
- Conditions
- Peripheral Nerve Disease, Peripheral Nerve Injury Lower Limb, Poliomyelitis, Cerebral Palsy
- Trial name
- ABCOGS (NCT04080687)
- Testing
- Ankle-foot orthosis
- Where
- Slovenia
- Volunteers
- 150 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Brain Injury, Chronic
Cross-cultural Adaptation to the Spanish Population and Validation of the Community Balance & Mobility Scale (S-CB&M)
Due to acquired brain injury (ABI), is often difficulty in gait and balance alterations, as problems that patients designated as the most disabling. It is essential to an effective assessment of the balance.
- Trial name
- S-CB&M (NCT04710147)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Castilla-La Mancha
Cardiovascular Disease Acute, Cardiomyopathies
The Role of Adaptive Immunity in COVID-19 Associated Myocardial Injury
COVID-19 is associated with complications including ARDS and myocardial injury, which informs prognosis and patient outcome. The laboratory plans to perform immunophenotyping of peripheral T-cells in patients with COVID-19 and…
- Conditions
- Cardiovascular Disease Acute, Cardiomyopathies, COVID
- Trial name
- NCT04340921
- Testing
- COVID-19 exposure
- Where
- United Kingdom
- Sponsor
- Barts & The London NHS Trust
Brain Injury, Chronic
Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy
The purpose of this study is to determine if hyperbaric oxygen therapy (HBOT) improves the cognitive function of OIF/OEF individuals who have chronic mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT00810615
- Testing
- Hyperbaric oxygen @ 2.4 ATA
- Volunteers
- 50 people
- Sponsor
- San Antonio Military Medical Center
Respiratory Tract Diseases, Respiratory Tract Infections
Assesment of the Endotracheal Tube Cuff Pressure Values in ICU Pateints Before and After Training Seminar
There is no accepted standard for the frequency of monitoring endotracheal tube cuff pressures (ETCP). the investigators plan on comparing two strategies for monitoring ETCP in mechanically ventilated patients.
- Conditions
- Respiratory Tract Diseases, Respiratory Tract Infections, Pneumonia, Ventilator-Associated, Ventilator-Induced Lung Injury
- Trial name
- NCT03401463
- Testing
- traning seminar
- Where
- Poland
- Volunteers
- 188 people
- Sponsor
- Jagiellonian University
Covid19, Diaphragm Injury
Respiratory Muscle Assesment in COVID-patients Without Hospitalization
Fatigue and exercise intolerance after survived COVID-19-infection might be related to weakness of the respiratory muscles. The aim of the project is to measure respiratory muscle function and strength in our respiratory…
- Trial name
- RMA-COVID-19 (NCT06105450)
- Testing
- Comprehensive assessment of respiratory muscle function.
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- RWTH Aachen University
Bronchopulmonary Dysplasia
Examining the Use of Non-Invasive Inhaled Nitric Oxide to Reduce Chronic Lung Disease in Premature Newborns
Bronchopulmonary dysplasia (BPD) is a serious lung condition that affects premature newborns. The condition involves abnormal development of lung tissue and is characterized by inflammation and scarring in the lungs.
- Trial name
- NCT00955487
- Testing
- Inhaled Nitric Oxide (iNO)
- Where
- 6 sites in United States
- Volunteers
- 124 people
- Sponsor
- University of Colorado, Denver
Bronchopulmonary Dysplasia, Lung Diseases
Inhaled NO in Prevention of Chronic Lung Disease
To test the hypothesis that low-dose inhaled nitric oxide administered to preterm infants who continue to require mechanical ventilation at 14 days of age will reduce the incidence of chronic lung disease.
- Trial name
- NCT00000548
- Testing
- mechanical ventilation
- Sponsor
- University of California, San Francisco
Renal Replacement Therapy, Acute Kidney Injury
PrEvalence of Acute and Chronic Kidney Disease Treated by Renal Replacement Therapy
A prospective international, multi-centre, prevalence study on the epidemiology of the use of renal replacement therapy for ICU patients who have acute kidney injury and chronic end stage kidney disease.
- Conditions
- Renal Replacement Therapy, Acute Kidney Injury, Chronic End Stage Kidney Disease
- Trial name
- PEACE (NCT02341885)
- Where
- Belgium
- Volunteers
- 2,000 people
- Sponsor
- European Society of Intensive Care Medicine
Traumatic Brain Injury
MENTOR Wellness Program
This randomized trial aims to determine the effectiveness a virtual wellness intervention program in individuals with traumatic brain injury (TBI).
- Trial name
- NCT06148324
- Testing
- MENTOR Program
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- NYU Langone Health
Kidney Injury, Antineoplastics Toxicity
Immune Checkpoint Inhibitors Nephrotoxicity
In recent years, immunotherapy has been postulated as one of the most effective strategy in the fight against cancer. The greatest success in this field has been achieved through the inhibition of molecules involved in the brake…
- Trial name
- NCT04902846
- Testing
- Early kidney damage biomarkers, Predisposition to kidney injury biomarkers
- Where
- 2 sites in Spain
- Volunteers
- 220 people
- Sponsor
- R. Laura Vicente Vicente
Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Randomized Study Comparing Metabolic Surgery With Intensive Medical Therapy to Treat Diabetic Kidney Disease
Proven therapy for DKD is primarily limited to RAAS blockers and SLGT2i. Weight reduction has the potential to become an additional and much needed treatment option.
- Conditions
- Diabetes Mellitus, Type 2, Kidney Disease, Chronic, Kidney Injury
- Trial name
- OBESE-DKD (NCT04626323)
- Testing
- Roux-en-Y gastric bypass, Best medical treatment
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
Hand Injuries, Hand Injuries and Disorders
Early Ultrasound-guided Nerve Block for Painful Hand Injuries in the Emergency Department
This study aims to determine whether early initiation of temporary nerve block therapy improves patient satisfaction, decreases patient pain and discomfort, decreases the use of dangerous medications such as narcotics, and frees…
- Trial name
- NCT03195413
- Testing
- Ultrasound-guided forearm nerve block, 1:1 volume measured solution of: 1% lidocaine without epinephrine and 0.5% bupivacaine without epinephrine, Bedside ultrasound machine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Washington
Critical Illness, Acute Gastrointestinal Injury
The Effect of Early Enteral Nutrition Feeding Process Assisted by Gastrointestinal Ultrasonography
In critical ill patients, feeding protocol is one of the important factor which determines the successful implementation of enteral nutrition（EN）.
- Trial name
- NCT05379582
- Testing
- Implement nutrition therapy according a procedure assisted by gastrointestinal ultrasound
- Where
- China
- Volunteers
- 294 people
- Sponsor
- Chinese Medical Association
Congenital Heart Disease, Brain Injuries
Autologous Umbilical Cord Blood Treatment of Neonate With CHD
The aim of the study is to evaluate the feasibility and safety and efficacy of collecting and infusing autologous umbilical cord blood (UCB) in newborn infants with hypoplastic left heart syndrome (HLHS) and transposition of…
- Conditions
- Congenital Heart Disease, Brain Injuries, Low Cardiac Output Syndrome, Neonatal Disorder
- Trial name
- NCT03558269
- Testing
- Autlogous UCB infusion
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Critical Illness, Acute Kidney Injury
Standard Dose Continuous Renal Replacement Therapy (CRRT) Versus Low-Dose CRRT ( KETZEREI )
Acute kidney injury (AKI) is a well-recognized complication in critically ill patients, which often leads to the necessity of mechanical kidney support (CRRT).
- Trial name
- KETZEREI (NCT06021288)
- Testing
- Effluent dose of CRRT
- Where
- 2 sites in Germany
- Volunteers
- 165 people
- Sponsor
- Universität Münster
Ventilator-associated Pneumonia, Traumatic Brain Injury
Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury
This randomized controlled trial will compare closed versus open endotracheal suctioning techniques for preventing ventilator-associated pneumonia (VAP) in adults with severe traumatic brain injury (TBI) who need mechanical…
- Trial name
- NCT07883083
- Testing
- Closed endotracheal suction system, Open endotracheal suction
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Minia University
Kidney Failure
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function
Tacrolimus is the standard immunosuppressive drug used to prevent organ rejection post liver transplant. One side effect of Tacrolimus is nephrotoxicity. Everolimus does not have the nephrotoxicity side effects of Tacrolimus.
- Trial name
- NCT04258423
- Testing
- Tacrolimus, Everolimus
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Concussion, Brain, Mild Traumatic Brain Injury
A Highly Portable Device for Assessment of Mild Traumatic Brain Injury in Deployed and Far-Forward Settings
The purpose of this study is to develop a highly portable, ruggedized diagnostic tool for concussion, EyeBOX Lens (EBLens), that can be utilized in deployed field and far-forward settings.
- Trial name
- NCT05527041
- Testing
- EyeBOX Lens (EBLens)
- Where
- United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Oculogica, Inc.
Acute Ischemic Stroke, Acute Renal Injury
Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation
The aim of this trial is to assess the safety and efficacy of conestat alfa (Ruconest®, Pharming Technologies B.V.) on renal and cerebral ischemic events in patients undergoing TAVI for severe symptomatic aortic stenosis (AS)…
- Trial name
- PAIR-TAVI (NCT05145283)
- Testing
- Conestat alfa (Ruconest®), NaCl 0.9%)
- Where
- 2 sites in Switzerland
- Volunteers
- 141 people
- Sponsor
- University Hospital, Basel, Switzerland
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