Clinical trials: Other Disease/Injury
Cardiogenic Shock, Renal Replacement Therapy
REnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO)
This retrospective study assesses long term renal outcome in patients having suffered medical or post cardiotomy refractory cardiogenic shock requiring renal replacement therapy (RRT) concomitant with veno-arterial extracorporeal…
- Conditions
- Cardiogenic Shock, Renal Replacement Therapy, Venoarterial Extracorporeal Membrane Oxygenation
- Trial name
- RECOVECMO (NCT05788211)
- Testing
- standard of care
- Where
- France
- Volunteers
- 93 people
- Sponsor
- University Hospital, Bordeaux
Amyotrophic Lateral Sclerosis (ALS)
Magnetic Resonance Imaging (MRI) in Amyotrophic Lateral Sclerosis (ALS)
This is a pilot study to identify the degree of grey and white matter involvement in patients with Amyotrophic Lateral Sclerosis (ALS) utilizing non-invasive techniques.
- Trial name
- NCT01945853
- Testing
- 7 Tesla MRI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Critical Illness, Acute Kidney Injury
Collective Accuryn Physiologic Signals and Signatures
The CAPSS Study is a retrospective and prospective, multi-center, single-arm post-market data collection study with an FDA cleared device.
- Conditions
- Critical Illness, Acute Kidney Injury, Sepsis, Septic Shock
- Trial name
- CAPSS (NCT03817281)
- Testing
- Accuryn Monitoring System
- Where
- United States
- Sponsor
- Potrero Medical
Chronic Traumatic Encephalopathy
Tau Imaging of Chronic Traumatic Encephalopathy
Chronic traumatic encephalopathy (CTE) is a progressive degenerative brain disease with symptoms that include memory loss, problems with impulse control, and depression that can lead to suicide.
- Trial name
- NCT02191267
- Testing
- [F18]-T807, [F18]-Florbetapir, MRI/MRS
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Brain Injury, Head Injury
S100 Biomarker in the Acute Management of Mild Head Injuries
A prospective validation study of the "Scandinavian guidelines for initial management of minimal, mild and moderate head injuries in adults".
- Trial name
- S100 (NCT02650765)
- Testing
- Indications for head CT imaging after acute head injury
- Where
- Finland
- Volunteers
- 295 people
- Sponsor
- Tampere University Hospital
Bronchopulmonary Dysplasia, Neonatal Disease
The Baby Lung Study
The introduction of exogenous surfactant therapy has significantly improved the mortality in preterm infants born between 23- and 28-weeks of gestation.
- Trial name
- NCT05152316
- Testing
- Observational study
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- University College, London
Lung Diseases, Bronchopulmonary Dysplasia
Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants
To determine whether or not inhaled nitric oxide (iNO) safely decreases the incidence of chronic lung disease (CLD) in premature infants.
- Trial name
- NCT00006401
- Testing
- iNO
- Where
- 14 sites in United States
- Volunteers
- 793 people
- Sponsor
- University of Colorado, Denver
Spinal Cord Injuries, Hypotension
Impact of Transcutaneous Spinal Stimulation on Blood Pressure and Orthostasis in Spinal Cord Injury
The purpose of this study is to learn whether stimulation applied to the spinal cord through the skin (called transcutaneous spinal stimulation) can help control blood pressure in people with a spinal cord injury.
- Conditions
- Spinal Cord Injuries, Hypotension, Orthostatic Hypotension, Spinal Cord Diseases
- Trial name
- (SCI) (NCT07674511)
- Testing
- Tilt test with stimulation (real-time effects): Intervention 1, 20 sessions of stimulation (Intervention 2)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Common Femoral Artery Injury, Other Vascular Adverse Event
Efficacy Study of Assiut Femoral Compression Device Versus Manual Compression in the Achievement of Hemostasis
This study was performed to evaluate the safety and efficacy of a locally designed Assiut Femoral Compression Device (AFCD) versus manual compression (MC).
- Trial name
- NCT02214030
- Testing
- Assiut Femoral Compression Device
- Where
- Egypt
- Sponsor
- Assiut University
Prematurity, Symptomatic Respiratory Disease
Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies
This is an observational study that proposes to collect clinical, physiological, cellular and molecular information in an attempt to identify a set of factors that may predict the risk for persistent lung disease in babies born…
- Conditions
- Prematurity, Symptomatic Respiratory Disease, Bronchopulmonary Dysplasia
- Trial name
- NCT01607216
- Where
- 2 sites in United States
- Volunteers
- 277 people
- Sponsor
- University of Rochester
Alzheimer Disease, Stroke
Assessment of Social-emotional Functioning in Neurological Diseases
Empathy, defined as the ability to understand others emotions, is a fundamental concept in social interactions. It is a psychological phenomenon involving various separable components : (i) the ability to feel and imagine the…
- Conditions
- Alzheimer Disease, Stroke, Parkinson's Disease, Lewy Body Dementia
- Trial name
- Emotion (NCT01339130)
- Testing
- Computerized tests and Electrophysiological measurements
- Where
- France
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Spinal Cord Injury, Sleep Apnea, Obstructive
Sleep-Disordered Breathing in Chronic SCI
The purpose of this study is to examine impact of Sleep Disordered Breathing (SDB) treatment in persons with chronic Spinal Cord Injury (SCI).
- Trial name
- NCT02176928
- Testing
- AutoPAP
- Where
- 4 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Miami
Trauma Injury, Trauma
The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma
Traumatic injury followed by critical illness provokes pathophysiologic changes in the bone marrow and the gut that contribute to persistent anemia and changes in the microbiome which significantly impact long-term recovery.
- Conditions
- Trauma Injury, Trauma, Critical Illness, Microbiome
- Trial name
- NCT06606119
- Testing
- Data and tissue collection
- Where
- 3 sites in United States
- Volunteers
- 275 people
- Sponsor
- University of Florida
Eustachian Tube Dysfunction, Middle Ear Barotrauma
Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury
- Trial name
- NCT04776967
- Testing
- Hyperbaric Compression Profile
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwell Health
Osteoarthritis, Knee
A Telehealth Study of a Wearable Electroceutical & Sports Sleeve for Knee Osteoarthritis Pain Relief & Improved Function
The purpose of this telemedicine 24-person open-label study is to evaluate the safety and usability of a proprietary wearable microcurrent electroceutical (a device that delivers micro-ampere electronic pulses) made by Healables…
- Trial name
- HEAL01WMCOA1 (NCT04938271)
- Testing
- HEAL-122 microcurrent electroceutical with e-textile sports knee sleeve
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Healables Ltd.
Respiratory Distress Syndrome, Adult, Gastrointestinal Hemorrhage
INR-Triggered Transfusion In GI Bleeders From ER
Transfusion-related acute lung injury (TRALI) is the most common cause of transfusion-related morbidity and mortality in the United States.
- Conditions
- Respiratory Distress Syndrome, Adult, Gastrointestinal Hemorrhage, Liver Diseases, Transfusion Related Lung Injury
- Trial name
- I-TRIGER (NCT01461889)
- Testing
- Transfuse plasma to High INR target, Transfuse plasma to Low INR target
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Perioperative Myocardial Infarction, Perioperative Myocardial Injury
Monitoring of Vital Signs for Phenotyping of Perioperative Myocardial Infarction/Injury After Noncardiac Surgery
The goal of this observational prospective cohort study is to learn about the pathophysiology of perioperative myocardial infarction/injury in high-risk patients undergoing major non-cardiac surgery.
- Trial name
- PMI-VITAL (NCT05866874)
- Where
- Switzerland
- Volunteers
- 875 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Kidney Injury, Critical Illness
REVERSE-AKI Randomized Controlled Pilot Trial
Observational studies among patients with acute kidney injury (AKI) have shown an association with fluid accumulation and increased mortality.
- Trial name
- REVERSE-AKI (NCT03251131)
- Testing
- Restrictive fluid management
- Where
- 7 sites in Australia, Belgium and 3 more
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Stress Disorders, Post-Traumatic, Sexually Transmitted Infection (STI) Prevention
Cognitive Processing Therapy to Treat PTSD and Sexually Transmitted Infections Among Men Who Have Sex With Men
Gay, bisexual, queer, and other men who have sex with men (GBM) continue to bear a disproportionate burden of the sexually transmitted and blood-borne infections (STBBI), largely attributable to efficient transmission during…
- Trial name
- CPT-T (NCT06463431)
- Testing
- Cognitive Processing Therapy
- Where
- 2 sites in Canada
- Volunteers
- 56 people
- Sponsor
- Toronto Metropolitan University
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