Clinical trials: Other Disorders of Autonomic Nervous System
Parkinson's Disease, Multiple System Atrophy
An Observational Study of Parkinson's Disease and Other Synucleinopathies (EASE-PD)
The study is a multi-center, observational study to evaluate the feasibility of α-synuclein-related biomarkers and imaging data in the disease diagnosis and prognosis evaluation in Synucleinopathies and healthy subjects.
- Trial name
- EASE-PD (NCT05638815)
- Where
- 4 sites in China
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- SciNeuro
Schizophrenia, Schizoaffective Disorder
Theta tACS During Working Memory Training: A Pilot Study of the Effects on Negative Symptoms of Schizophrenia
In this randomized double-blind trial, we investigated whether externally induced left-hemispheric frontoparietal theta synchronization by multi-electrode online theta (6Hz) transcranial alternating current stimulation (tACS)…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Negative Symptoms, Working Memory Training
- Trial name
- NCT04545294
- Testing
- Theta tACS
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Parkinson Disease
The Role of the Noradrenergic System in the Nonmotor Symptoms of Parkinson's Disease
The goal of this clinical trial is to learn about the role of noradrenergic system in the non-motor symptoms of Parkinson's disease. The main objectives it aims to answer are: 1.
- Trial name
- NAinPD (NCT04346394)
- Testing
- Yohimbine HCl
- Where
- United States
- Sponsor
- Nathaniel M. Robbins
Complex Regional Pain Syndrome Type I of the Upper Limb, Unilateral Limb Pain of Other Origin
Correlation Between 3 Phase Bone Scintigraphy and Pressure Pain Thresholds in Patients With Complex Regional Pain Syndrome (CRPS)
The aim of the study is to investigate the correlation between increased bone metabolism in the 3 phase bone scintigraphy (TPBS) and decreased pressure pain thresholds in patients with complex regional pain syndrome (CRPS) of the…
- Conditions
- Complex Regional Pain Syndrome Type I of the Upper Limb, Unilateral Limb Pain of Other Origin, Healthy Subjects
- Trial name
- NCT01623141
- Testing
- Pressure Pain measurement
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Parkinson Disease, Parkinsonism
Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism
The purpose of this study is to determine whether identification of misfolded proteins in the skin will help to determine what sort of parkinsonism someone has.
- Conditions
- Parkinson Disease, Parkinsonism, Dementia With Lewy Bodies, Multiple System Atrophy
- Trial name
- NCT04518059
- Testing
- punch skin biopsy
- Where
- 2 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Parkinsonian Disorders
Post-prandial Hypotension and Sleepiness in Parkinson's Disease and Other Synucleinopathies
Excessive daytime sleepiness (EDS) is observed in 30 to 50 % of patients with Parkinson's disease (PD) patients, Dementia with Lewy Bodies (DLB) and Multiple System Atrophy (MSA).
- Trial name
- HYPOSOMNPARK (NCT02021903)
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Toulouse
Complex Regional Pain Syndromes, Neuralgia
Forms of Cervical Brachial Syndrome Treated With Plasma Concentrate Enriched for A2M
Alpha 2 macroglobulin (A2M) is a plasma protein that acts as a molecular trap for inflammatory factors such as tumor necrosis factor (TNF). After plasma is enriched for A2M, it may be injected for treating chronic inflammation.
- Conditions
- Complex Regional Pain Syndromes, Neuralgia, Thoracic Outlet Neurologic Syndrome
- Trial name
- A2M (NCT04066933)
- Testing
- A2M enriched plasma
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Neurological Associates of West Los Angeles