Clinical trials: Other Metabolic Diseases
Obesity, Weight Loss
Does Use of the Voy Program Improve Weight Loss Percentage and Other Health Outcomes in a Population Already Taking GLP/GIP-1RA Medication?
The aim of the trial is to assess the impact of the Voy Program on weight loss and other health outcomes in an obese population already approved for GLP/GIP-1RA medication.
- Trial name
- VOYAGER (NCT06710587)
- Testing
- Voy Program
- Volunteers
- 470 people
- Sponsor
- Menwell Limited
SARS-CoV2 Infection Common Pathogens, Diabetes Mellitus, Type 1
Characterisation of the Immune Response to SARS-CoV-2 Infection / COVID-19 in Type 1 Diabetes
Emerging clinical details of the current SARS-CoV-2 pandemic have illustrated that there are multiple clinical presentations and outcomes of this viral infection.
- Trial name
- TIRID (NCT05171998)
- Testing
- venous blood sample
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Cwm Taf University Health Board (NHS)
HIV, Metabolic Syndrome
Incidence of HANA Conditions in HIV-infected Individuals
With the availability of effective anti-retroviral therapy, HIV-infected individuals are expected not to die of AIDS and have longer life expectancy.
- Conditions
- HIV, Metabolic Syndrome, Osteopenia, Osteoporosis
- Trial name
- NCT03483584
- Where
- Hong Kong
- Volunteers
- 215 people
- Sponsor
- Chinese University of Hong Kong
Diabetes Mellitus
Swiss Diabetes Registry - SwissDiab Study
Currently, the estimated number of people with diabetes mellitus is approximately 387 million people worldwide. Due to population growth, urbanization, ageing and the rising prevalence of obesity the numbers of individuals with…
- Trial name
- SwissDiab (NCT01179815)
- Where
- 4 sites in Switzerland
- Volunteers
- 1,500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Obesity
Situation and Evolution of the Misuse of Alcohol and Other Addictive Behaviors in Obese Patients Being Managed at Nîmes University Hospital
Obesity is a multifactorial pathology in which external (lifestyle, environment) and internal (psychological or biological, especially genetic) factors are involved. These are responsible for a positive energy balance.
- Trial name
- ADOB (NCT04613791)
- Testing
- Blood test
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Obesity
Rimonabant in Abdominally Obese Patients With Impaired Fasting Blood Glucose
Primary objective: To determine the effect of Rimonabant 20mg on the co-primary endpoint including Fasting Plasma Glucose (FPG), HDL-Cholesterol (HDL-C) and triglyceride (TG) levels over a period of 12 months when prescribed with…
- Trial name
- PRADO (NCT00405808)
- Testing
- Rimonabant
- Where
- 27 sites in Austria, Belgium and 25 more
- Volunteers
- 2,666 people
- Sponsor
- Sanofi
Schizophrenia, Type 2 Diabetes Mellitus
Janssen - Glucose Regulation/Risp/Olanz
Abnormalities in peripheral glucose regulation and type 2 diabetes can occur more commonly in individuals with schizophrenia than in healthy subjects or in other psychiatric conditions.
- Trial name
- NCT00205738
- Testing
- Risperidone, Olanzapine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus Type 2
A Study of Dipeptidyl-peptidase IV (DPP-IV) RO4876904 in Patients With Type 2 Diabetes.
This 5 arm study will assess the efficacy, pharmacokinetics, safety and tolerability of a DPP-IV inhibitor compared to placebo in patients with type 2 diabetes.
- Trial name
- NCT00502710
- Testing
- RO4876904
- Where
- 48 sites in United States, Australia and 7 more
- Volunteers
- 289 people
- Sponsor
- Hoffmann-La Roche
Sickle Cell Disease, Transfusion Dependent Alpha- or Beta- Thalassemia
Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies
This is a study to collect the outcomes of stem cell transplantation for patients with hematologic diseases other than cancer.
- Conditions
- Sickle Cell Disease, Transfusion Dependent Alpha- or Beta- Thalassemia, Diamond Blackfan Anemia, Paroxysmal Nocturnal Hemoglobinuria
- Trial name
- NCT02179359
- Testing
- Reduced Toxicity Ablative Regimen, Reduced Intensity Preparative Regimen, Myeloablative Preparative Regimen
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Hyperlipidemia, Cardiovascular Diseases
The Effect of Strawberries in a Cholesterol-Lowering Dietary Portfolio
The purpose of this study is to determine whether addition of strawberries to a dietary portfolio of cholesterol-lowering foods will improve compliance and so increase the effectiveness of the dietary portfolio in lowering…
- Conditions
- Hyperlipidemia, Cardiovascular Diseases, Hypercholesterolemia
- Trial name
- NCT00345722
- Testing
- strawberry dietary intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes, Diabetes Mellitus, Type 1
Observational Study on Levemir® in Obese Diabetic Patients
This study is conducted in Europe. The aim of this observational study is to investigate the effect of switch from other basal insulin treatments to Levemir® on body weight in obese diabetic patients.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- KILOS (NCT00849342)
- Testing
- insulin detemir
- Where
- 2 sites in Netherlands, Slovenia
- Volunteers
- 580 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus, Type1 Diabetes Mellitus
China Diabetes Registry by Metabolic Management Center
Epidemiologic studies have revealed a tremendous increase in the prevalence of diabetes and related mortality worldwide. In order to meet all the challenges in the treatment of metabolic diseases in China, the National Metabolic…
- Conditions
- Type 2 Diabetes Mellitus, Type1 Diabetes Mellitus, Monogenetic Diabetes, Pancreatogenic Diabetes
- Trial name
- CDR-MMC (NCT03811470)
- Testing
- Standard diabetes management model in each MMC center
- Where
- China
- Volunteers
- 1,000,000 people
- Sponsor
- Guang Ning
Obesity, Prostate Cancer
Effect of Lap-Band Induced Weight Loss on Serum PSA Levels
The proposed prospective study aims to determine whether interpretation of PSA levels in morbidly obese men require correction due to the obesity itself.
- Trial name
- NCT00562341
- Testing
- Bariatric Surgery
- Where
- United States
- Sponsor
- Maimonides Medical Center
Randomized Controlled Trial
Feasibility and Preliminary Effect of Baduanjin Program for People Diagnosed With Schizophrenia
Introduction Low levels of physical activity and central obesity contribute to metabolic syndrome in patients with schizophrenia.
- Trial name
- NCT04027634
- Testing
- Baduanjin program
- Volunteers
- 22 people
- Sponsor
- National Yang Ming Chiao Tung University
Schizophrenia
Study of Aripiprazole in Patients With Schizophrenia- Effects on Glucose Metabolism-
The objective of this study is to examine the effects of aripiprazole on glucose metabolism in schizophrenic patients without hyperglycemia and diabetes mellitus or any history thereof.
- Trial name
- NCT00392197
- Testing
- Aripiprazole
- Where
- 5 sites in Japan
- Volunteers
- 111 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Thyroid Gland Carcinoma
An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy
This trial investigates whether hyperpolarized magnetic resonance imaging (hpMRI) can predict treatment response in patients with thyroid cancer and other malignancies of the head and neck undergoing radiation therapy and/or…
- Trial name
- NCT04589624
- Testing
- Hyperpolarized Carbon C 13 Pyruvate, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Schizophrenia
Study on Metabolic Parameters of Sertindole in Patients With Schizophrenia
The purpose of this exploratory study is to evaluate the effects of sertindole and olanzapine on metabolic parameters and syndrome in patients with schizophrenia.
- Trial name
- NCT00759460
- Testing
- Sertindole, Olanzapine
- Where
- China
- Volunteers
- 250 people
- Sponsor
- H. Lundbeck A/S
Metabolic Complications
Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
We hypothesize that metformin co-administered with olanzapine will be well tolerated and associated with significantly less insulin resistance, weight gain and dyslipidemia as compared to olanzapine plus placebo.
- Trial name
- NCT00682448
- Testing
- Metformin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rush University Medical Center
Vitamin D Deficiency, Vascular Calcification
Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis
Aim: To investigate whether cholecalciferol (4800 U/daily) or placebo for 16 weeks reduces proteins levels associated with vascular calcification (osteoprotegerin, osteopontin, osteocalcin) in patients treated with peritoneal…
- Conditions
- Vitamin D Deficiency, Vascular Calcification, Renal Insufficiency, End Stage Renal Failure on Dialysis
- Trial name
- NCT02598635
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Malnutrition
The Dietetic Consultation: an Illuminative Evaluation
This study aims to understand the experience of the dietetic consultation from the perspective of nutritionally vulnerable older patients receiving oral nutrition support and dietitians, as well as other key stakeholders involved…
- Trial name
- NCT03509116
- Testing
- Observations, documents, Interviews, key stakeholders, documents
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- King's College London