Clinical trials: Other Surgical Procedures
Pain, Other Surgical Procedures
Comparison of the Clinical Efficacy of Naproxen, Associated or Not With Esomeprazol, in Lower Third Molar Removal
The present clinical trial randomized compared the clinical efficacy of the naproxen associated or not with esomeprazol, for the removal of lower third molars.
- Conditions
- Pain, Other Surgical Procedures, Impacted Third Molar Tooth
- Trial name
- NCT02494856
- Testing
- Surgery with Naproxen, Surgery with Naproxen and Esomeprazole
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Giovana Maria Weckwerth
Other Functional Disturbances Following Cardiac Surgery, Postoperative Hemorrhage
A Gray Zone Approach of Rotational Thromboelastometry for Predicting Postoperative Bleeding in Cardiac Surgical Patients
Rotational thromboelastometry (ROTEM) is reliable point of care management of coagulation disorder undergoing surgery. Recently, there are some reports about prediction of perioperative bleeding using ROTEM.
- Conditions
- Other Functional Disturbances Following Cardiac Surgery, Postoperative Hemorrhage, Coagulation Defect; Bleeding
- Trial name
- NCT01889732
- Testing
- ROTEM
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Lung Cancer
Vibration Response Imaging (VRI) in Lung Cancer Patients
Primary Objective: To estimate the accuracy of the pre-operative VRI QRF (Quantitative Regional Function) results versus the gold standard QRRVP (Quantitative Radionuclide Study of Regional Lung Ventilation and Perfusion)…
- Trial name
- NCT00506467
- Testing
- Vibration Response Imaging
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Medication Adherence, Antibiotic Resistance, Microbial
7-VINCut Antibiotic Stewardship Intervention to Decrease Duration of Antibiotic Treatment and Carbapenem Use in Surgery
Antimicrobial resistance (AMR) is one of the top ten public health threats facing humanity. The misuse and overuse of antibiotics has been identified as a major factor in the development of drug-resistant pathogens, and 30% of…
- Conditions
- Medication Adherence, Antibiotic Resistance, Microbial, Medication Errors and Other Product Use Errors and Issues
- Trial name
- 7_VINCUT (NCT05813821)
- Testing
- Antimicrobial stewardship in surgery
- Where
- Spain
- Volunteers
- 32,499 people
- Sponsor
- Hospital de Granollers
Other Surgical Procedures
Video Double-Lumen Tube Prospective Randomized Study
The goal of this clinical research study is to learn how often a fiberoptic bronchoscopy (FOB -- also known as a fiberoptic scope procedure) needs to be used with a video double lumen tube (VDLT) during surgeries that require…
- Trial name
- NCT02429414
- Testing
- Non-Video Double Lumen Tube (DLT), Fiberoptic Bronchoscopy (FOB), Video Double Lumen Tube (VDLT)
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- M.D. Anderson Cancer Center
Non-small Cell Lung Cancer Stage III
Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features
The goal of this clinical trial is to learn about neoadjuvant cemiplimab with histology-specific chemotherapy followed by resection and adjuvant cemiplimab in stage 3 non-small cell lung cancer (NSCLC) with select N3 lymph node…
- Trial name
- NEO-SURG (NCT06449313)
- Testing
- Cemiplimab-Rwlc
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Georgetown University
Head and Neck Cancer
Head and Neck Cancer Registry (LORHAN)
The primary objective of this study is to describe, in detail, patterns of care for head and neck carcinoma patient
- Trial name
- LORHAN (NCT01080313)
- Testing
- Therapy for head and neck cancer
- Where
- United States
- Volunteers
- 26,000 people
- Sponsor
- Eli Lilly and Company
Breast Cancer, Elderly Patient
A Prospective Cohort Study Comparing Disparity in Surgical Procedure (Wide Local Excision Only vs Any Other Surgery Procedures) Among the Elderly Breast Cancer Patients
The incidence and mortality rates of breast cancer are still increasing in both developing and developed countries. The number of women ≥70 years who are affected by breast cancer (BC) worldwide is also on the increase.
- Conditions
- Breast Cancer, Elderly Patient, Wide Local Excision, Surgery
- Trial name
- NCT04426136
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Enteroendocrine Physiological Changes in Superobese Patients Submitted to Two Different Bariatric Procedures, Determine Whether BPD With DS or SADI-S as Primary or Revisional Surgery is Superior Than the Other as First Choice for the Superobese
Surgical Innovation for Diabetes Treatment 2
This study aims to understand the enteroendocrine physiological changes in superobese patients submitted to two different bariatric procedures (biliopancreatic diversion with duodenal switch versus single anastomosis…
- Conditions
- Enteroendocrine Physiological Changes in Superobese Patients Submitted to Two Different Bariatric Procedures, Determine Whether BPD With DS or SADI-S as Primary or Revisional Surgery is Superior Than the Other as First Choice for the Superobese, Determine Whether or Not Revision Surgery is as Effective as Primary Surgery and Understand the Physiological Mechanisms Inherent in These Putative Differences
- Trial name
- SURIDIAB2 (NCT04712409)
- Testing
- Single anastomosis duodeno-ileal bypass, Biliopancreatic diversion with duodenal switch, SADI-S as a revisional procedure
- Where
- 2 sites in Portugal
- Volunteers
- 40 people
- Sponsor
- Hospital de Sao Sebastiao
Hypertrophic Surgical Scar, Medical Adhesive Related Skin Injury
Surgical Dressing Study Comparing SYLKE vs Other Common Incisional Dressings Following Abdominoplasty/Panniculectomy Patients
Include primary, secondary, and exploratory objectives. Primary Goal: To compare the effects of a silk fibroin-based dressing versus standard postoperative dressings on scar quality.
- Trial name
- NCT07878390
- Testing
- SYLKE, Dermabond Prineo, Paper Tape
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity, Obesity, Morbid
Luso-Cor Stent Compared to Other Endoscopic Techniques for Management of Fistulas and Anastomotic Dehiscences(ES-LCCE-UDFM)
The global prevalence of obesity has prompted an increase in bariatric surgery, which is the only management strategy that provides long-term weight loss and improvement of obesity-related diseases.
- Conditions
- Obesity, Obesity, Morbid, Esophageal Cancer, Esophageal Neoplasms
- Trial name
- ES-LCCE-UDFM (NCT06862479)
- Testing
- Endoscopic management of fistulas with stents or vacum therapy
- Where
- Portugal
- Volunteers
- 180 people
- Sponsor
- Unidade Local de Saúde Santa Maria
Staphylococcal Infections, Meningitis
Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections
Methicillin-resistant Staphylococcus aureus (SA) is a major pathogen causing mainly health-care associated infections and, lately, also community acquired infections. Few treatment choices exist to treat these infections.
- Conditions
- Staphylococcal Infections, Meningitis, Sepsis, Pneumonia
- Trial name
- NCT00427076
- Testing
- Cotrimoxazole, Vancomycin
- Where
- 2 sites in Israel
- Volunteers
- 252 people
- Sponsor
- Rabin Medical Center
Anesthesia; Reaction, Adverse Effect of Other General Anesthetics
Influence of Anesthesia Technique on Postoperative Evolution After Urogenital Surgical Interventions
The study hypothesis is that regional anesthesia offers better outcome for the patients who underwent robot assisted laparoscopic urogenital surgery.
- Conditions
- Anesthesia; Reaction, Adverse Effect of Other General Anesthetics, Adverse Anesthesia Outcome, Acute Kidney Injury
- Trial name
- ROBOTNGAL (NCT01898897)
- Testing
- epidural catheter insertion, robot assisted laparoscopic urogenital surgery
- Where
- Romania
- Volunteers
- 60 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Hypertension, Pulmonary
Riociguat in Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
The aim of the study is to assess safety, tolerability and clinical effects of different doses of riociguat in patients with inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and who are not satisfactorily treated…
- Trial name
- EAS (NCT01784562)
- Testing
- Adempas (Riociguat, BAY63-2521)
- Where
- 102 sites in United States, Austria and 18 more
- Sponsor
- Bayer
Urinary Incontinence, Urinary Stress Incontinence
Pregnancy After Tension-free Vaginal Tape and Other Mid-urethral Sling Procedures
The purpose of this study is to determine the interactions between pregnancy and urinary stress incontinence in women with a mid-urethral sling (MUS).
- Conditions
- Urinary Incontinence, Urinary Stress Incontinence, Pregnancy Complications
- Trial name
- PregnanT (NCT02999347)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Pelvic Organ Prolapse, Stress Urinary Incontinence
Outcomes of Pelvic Surgery With and Without Anti-incontinence Procedure in Occult Stress Urinary Incontinence Patients
1. To evaluate whether a standardized tension-free vaginal tape-obturator(TVT-O) procedure, when added to a planned improved reconstruction pelvic surgery, improves the rate of urinary stress continence in subjects with occult…
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Other Specified Urinary Incontinence
- Trial name
- PTOS (NCT02193607)
- Testing
- TVT-O, Improved reconstruction pelvic surgery
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Peking Union Medical College Hospital
Mohs Surgery
Briagen Observational Study
This research study is evaluating a study product called Briagen™ as a possible treatment for wound healing after Mohs procedure.
- Trial name
- BOS (NCT04090970)
- Testing
- Briagen
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Gemstone Biotherapeutics
Hemophilia A
Phase 3 Efficacy and Safety Study of BAX 855 in Severe Hemophilia A Patients Undergoing Surgical Procedures
The purpose of the study is to evaluate the efficacy and safety of BAX 855 in severe hemophilia A previously treated (PTP) males, 12 to 65 years of age who are undergoing elective surgical or other invasive procedures.
- Trial name
- NCT01913405
- Testing
- PEGylated Recombinant factor VIII (rFVIII)
- Where
- 22 sites in United States, Bulgaria and 7 more
- Volunteers
- 30 people
- Sponsor
- Baxalta now part of Shire
Other Complications of Surgical and Medical Procedures
Use of McGrath Videolaryngoscope to Assist Transesophageal Echocardiography Probe Insertion in Intubated Patients
The primary aim of this study is to investigate the difference in the first attempt and overall success rate of different techniques for insertion of transesophageal echocardiography.
- Trial name
- NCT02634047
- Testing
- conventional technique, videolaryngoscope technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Antalya Training and Research Hospital
Blood Loss, Surgical, Coagulation Disorder
Phase 3 Trial of Reltodecacog Alfa (VMX-C001) vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.
The goal of this clinical trial is to learn if reltodecacog alfa (VMX-C001) works to to allow blood clotting control in participants who take FXa Direct Oral Anticoagulants (DOACs) during surgery or other invasive procedures that…
- Trial name
- EQUILIBRIX-S (NCT07288489)
- Testing
- Reltodecacog alfa, Usual Pharmacological Care
- Where
- 77 sites in United States, Australia and 16 more
- Volunteers
- 800 people
- Sponsor
- VarmX B.V.