Clinical trials: Otitis Media Chronic
Tympanic Membrane Perforation, Chronic Otitis Media
Platelet-Rich Fibrin in Revision Cartilage Tympanoplasty
The aim of this study is to evaluate the success rate of revision surgery using a conchal cartilage graft supported with autologous platelet-rich fibrin (PRF), performed under local anesthesia, in patients who previously…
- Trial name
- NCT07893418
- Testing
- PRF-supported conchal cartilage tympanoplasty under local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Otitis Media With Effusion, Laryngopharyngeal Reflux
Three Methods Used in the Diagnosis of EER in Children With OME
Detection of extraesophageal reflux (EER) in children with chronic otitis media with effusion (OME) using three different diagnostic methods and selection of the group of patients with severe EER who could potentially benefit…
- Trial name
- NCT02183961
- Testing
- Restech, Peptest, Detection of pepsin in adenoid specimen
- Where
- Czechia
- Volunteers
- 24 people
- Sponsor
- University Hospital Ostrava
Balloon Eustachian Tuboplasty
The Therapeutic Effect of BET in COM With ETD
Currently, surgical treatment of patients with chronic otitis media is one of the most important treatment methods. However, the current results show that some patients with eustachian tube dysfunction can't reconstruct the…
- Trial name
- NCT03440710
- Testing
- BET
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Chronic Otitis Media
Validation of a Questionnaire for Measuring Quality of Life in Patients With Chronic Inflammation of the Middle Ear
For measuring quality of life in patients with chronic inflammation of the middle ear, only two questionnaires currently exist. However, these questionnaires are designed only to measure either disease-specific health or…
- Trial name
- NCT02226718
- Testing
- Administration of questionnaire
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Chronic Otitis Media, Age Determined Bacteria
Bacterial Assessment of Middle Ear Fluid in Children Undergoing Ventilation Tube Placement Surgery
Children with chronic otitis media have more resistant bacteria that require surgical intervention to eradicate the infections. The study will evaluate the dominant bacteria and their sensitivities to antibiotics.
- Trial name
- NCT01157910
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Respiratory Tract Infections
Procalcitonin Guided Antibiotic Use in Acute Respiratory Tract Infections (PARTI)-Study
Acute respiratory tract infections (ARTI) are among the most frequent reasons for seeking medical attention in primary care. Although from predominantly viral origin, ARTIs are the most important condition for the prescription of…
- Trial name
- NCT00099840
- Testing
- Procalcitonin guided antibiotic therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Otitis Media With Effusion, Sleep Disturbances
The Effect of Tympanostomy Tube Insertion on Sleep in Children With Chronic Otitis Media With Effusion
The purpose of this study is to investigate the prevalence of sleep disturbances in children with Chronic Otitis Media with Effusion (COME) and the effect of tympanostomy tube insertion (TTI) on sleep disturbances.
- Trial name
- NCT02477735
- Testing
- Actigraphy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Otitis Media With Effusion in Children, Quality of Life
Short-term Effects of Ventilation Tubes in Children With Chronic Otitis Media With Effusion
The goal of this clinical, randomized trial is to compare the sleeping patterns and quality of life of children with chronic otitis media with effusion (OME) with or without tympanic tubes insertion.
- Conditions
- Otitis Media With Effusion in Children, Quality of Life, Sleep
- Trial name
- NCT06100159
- Testing
- Tympanostomy tube insertion
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Chronic Otitis Media
Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement
This is a study to compare intranasal dexmedetomidine to intranasal fentanyl following anesthesia induction in patients undergoing myringotomy and placement of pressure equalization (PE) tubes in providing analgesia and smoothing…
- Trial name
- NCT01188551
- Testing
- Dexmedetomidine, Fentanyl, Midazolam
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nationwide Children's Hospital
Otitis Media Chronic, Cholesteatoma
The Serum Sclerostin Levels in Cholesteatoma Patients
The aim of this study is to investigate the levels of sclerostin in patients with cholesteatoma. So far, there is no study showing the levels of sclerostin in cholesteatoma.
- Trial name
- NCT03954288
- Testing
- serum for sclerostin ELISA test
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Abant Izzet Baysal University
Cholesteatoma, Chronic Otitis Media
Combined Access Closed Tympanomastoidectomy: Microsurgery Allied to Endoscopy
Chronic otitis media is a prevalent medical condition, leading to important impact in the lives of the individuals with this condition, and a great amount of patients may need surgical intervention.
- Trial name
- NCT03294421
- Testing
- combined access tympanomastoidectomy, standard closed tympanomastoidectomy
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Otitis Media, Otitis Media Chronic
SWIR Otoscopy Study
The aim of this study is to provide preliminary data to support future studies to demonstrate that the short wave infrared (SWIR) otoscope is a better diagnostic tool than a white light otoscope for diagnosing middle ear…
- Conditions
- Otitis Media, Otitis Media Chronic, Otitis Media Effusion
- Trial name
- NCT06944795
- Testing
- SWIR device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Chronic Otitis Media With Effusion in Chronic Sinusitis With Polyps
The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear.
- Trial name
- NCT03975842
- Testing
- Sinonasal and otologic evaluation
- Volunteers
- 80 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Tympanic Membrane Perforation, Chronic Otitis Media
Boomerang-Shaped Cartilage Graft in Endoscopic Tympanoplasty
This study evaluates the anatomical and functional outcomes of using a boomerang-shaped chondroperichondrial graft in endoscopic Type I tympanoplasty for repairing anterior or subtotal tympanic membrane perforations.
- Trial name
- NCT07823894
- Testing
- Endoscopic Type I Tympanoplasty with Boomerang-Shaped Chondroperichondrial Graft
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hearing Impaired Children, Glue Ear
Exploring Interventions for Glue Ear During Covid-19
During the Coronavirus pandemic children's hearing services are closed or reduced and grommet operations are part of the lowest priority group.
- Conditions
- Hearing Impaired Children, Glue Ear, Hearing Loss, Conductive
- Trial name
- BIG-C (NCT04427631)
- Testing
- Bone conduction headphones
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Cambridgeshire Community Services NHS Trust
Chronic Otitis Media
The Effects of Chronic Otitis Surgery on SVV
Inner ear trauma during chronic otitis surgery is one of the major concerns of Otolaryngology. Hearing thresholds or semicircular canals were investigated with this purpose.
- Trial name
- NCT04396145
- Testing
- Subjective Visual Vertical
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Complement Deficiency, Antibody Deficiency
Systematic Search for Primary Immunodeficiency in Adults With Infections
Antibody deficiencies and complement deficiencies are the most frequent Primary immunodeficiencies (PIDs) in adults, and are associated with greatly increased susceptibility to recurrent and/or severe bacterial infections …
- Conditions
- Complement Deficiency, Antibody Deficiency, Chronic Sinus Infection, Meningitis, Bacterial
- Trial name
- SPIDAC (NCT02972281)
- Testing
- Immunological diagnosis tests
- Where
- 19 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Lille
Chronic Otitis Media
Tegmen Defect Management During Mastoidectomy
In this study, we aimed to discuss our clinical experience on the management of the tegmen defects which were revealed during the mastoidectomy surgeries.
- Trial name
- NCT04374266
- Testing
- physical examination, and computerized tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Medeniyet University
Otitis Media, Otitis Media Effusion
Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media
The goal of this clinical trial is to learn whether osteopathic manipulative treatment, or OMT, can reduce the need for tympanostomy tube surgery in children with recurrent or chronic otitis media who have been referred to an…
- Conditions
- Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children
- Trial name
- NCT07639775
- Testing
- Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sarah Vidal
Chronic Otitis Media, Cholesteatoma
A Study of the Clinicopathologic Behaviour of the Different Types of Unsafe Chronic Otitis Media
The purpose of the study is to study the clinicopathologic behaviour of the 3 dangerous types of chronic otitis media that are prone for complications.
- Trial name
- NCT00270660
- Testing
- biopsy, audiometry, ET function test, ear swab culture, DNE
- Where
- India
- Volunteers
- 192 people
- Sponsor
- Karnataka Institute of Medical Sciences