Clinical trials: Otitis Media Recurrent
Recurrent Acute Otitis Media, Acute Otitis Media
Efficacy of the EarPopper Device in Children With Recurrent Otitis Media
This is a randomized controlled clinical trial evaluating the efficacy of the EarPopper device (EP) in the reduction of episodes of acute otitis media (AOM) in children with recurrent otitis media.
- Trial name
- NCT03534219
- Testing
- EarPopper
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Acute Otitis Media
Herbal-Based Medication vs. Placebo in Preventing Acute Otitis Media in Children at High Risk of Recurrence
The purpose of this study is to study whether a herbal-based medication is superior to placebo for prevention of acute otitis media in pre-school children with upper respiratory tract infection.
- Trial name
- OTV_PRE_01 (NCT02345447)
- Testing
- Herbal-based medication
- Where
- Germany
- Volunteers
- 296 people
- Sponsor
- University Hospital Tuebingen
Otitis Media With Effusion (OME), Eustachian Tube Dysfunction
Autoinflation as a Eustachian Tube Rehabilitation
This randomized controlled trial evaluated the effectiveness of autoinflation in preventing recurrence of otitis media with effusion (OME) and reducing the need for reoperation after tympanostomy tube (TT) extrusion in children.
- Trial name
- NCT07122999
- Testing
- Eustachi
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Pusan National University Hospital
Otitis Media
Nasal Xylitol in the Prevention of Otitis Media
Acute otitis media (AOM) is one of the most prevalent and costly illnesses in children throughout the world. AOM can lead to chronic otitis media with effusion (OME) resulting in conductive hearing loss that can cause speech…
- Trial name
- NCT02592382
- Testing
- Xylitol spray
- Where
- 2 sites in Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Preterm Birth, Preeclampsia
The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health
The 'Standard of Care Plus' ('PLUS') model in the ROOT Study consists of analyzing select micronutrient and gene variants of pregnant females to construct trimester-specific and personalized nutrition and lifestyle…
- Conditions
- Preterm Birth, Preeclampsia, Gestational Diabetes Mellitus (GDM), Small for Gestational Age (SGA)
- Trial name
- ROOT (NCT07559773)
- Testing
- 'Standard of Care PLUS'
- Volunteers
- 500 people
- Sponsor
- GrowBaby Life Project
Otitis Media
Prevention Recurrent Otitis Media in the Young Children
The purpose of this study is to find out if young children have more benefit of the combination of adenotomy and tympanostomy than plain tympanostomy in prevention of recurrent otitis media.
- Trial name
- NCT00162994
- Testing
- adenoidectomy and tymapanostomy
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Oulu University Hospital
Recurrent Upper-Respiratory Tract Infections
CLEARI (Clinical Efficacy Assessment on Recurrent Upper-Respiratory Tract Infections) Study
The purpose of this study is to assess the efficacy and safety of J022X ST for prevention of Recurrent Upper-Respiratory Tract Infections (RURTI) compared to placebo in children of younger age who develop infectious diseases more…
- Trial name
- NCT01948856
- Testing
- J022X ST
- Where
- 24 sites in Italy, Lithuania and 3 more
- Volunteers
- 1,003 people
- Sponsor
- Pierre Fabre Medicament
Otitis Media in Children, Chronic Otitis Media With Effusion
Posterior vs. Anterior Tympanostomy Tube Placement
The goal of this randomized clinical trial is to compare the results of ear tube placement in two different parts of the ear drum. The ear drum can be divided into four parts (called quadrants).
- Conditions
- Otitis Media in Children, Chronic Otitis Media With Effusion, Recurrent Acute Otitis Media
- Trial name
- NCT06191562
- Testing
- Tympanostomy tube
- Where
- 2 sites in United States
- Volunteers
- 386 people
- Sponsor
- David Chi, MD
Recurrent Acute Otitis Media
Effect of Ventilation Tubes in Otitis-prone Children
The purpose of this study is to investigate the effects of ventilation tubes in children with recurrent ear infections. By drawing lots, young children with recurrent ear infections will be assigned to one of two groups…
- Trial name
- NCT05348291
- Testing
- ventilation tubes
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University
Tympanic Membrane Perforation, Chronic Otitis Media
Platelet-Rich Fibrin in Revision Cartilage Tympanoplasty
The aim of this study is to evaluate the success rate of revision surgery using a conchal cartilage graft supported with autologous platelet-rich fibrin (PRF), performed under local anesthesia, in patients who previously…
- Trial name
- NCT07893418
- Testing
- PRF-supported conchal cartilage tympanoplasty under local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Acute Otitis Media
Effect of a New Probiotic Strain on Recurrent Acute Otitis Media in Children (PROMAR)
An interventional, randomized, double-blind, placebo-controlled study will be conducted to investigate the effect of a new probiotic strain Lactobacillus salivarius PS7 on Acute Otitis Media (AOM) in children with recurrent AOM…
- Trial name
- PROMAR (NCT03614117)
- Testing
- Lactobacillus salivarius PS7 during 6 months, Lactobacillus salivarius PS7 during 3 months
- Where
- Spain
- Volunteers
- 222 people
- Sponsor
- ProbiSearch SL
Acute Otitis Media, Chronic Otitis Media
Anesthetic Effect of Lidocaine/Epinephrine Solution Delivered Via Iontophoresis to External Auditory Apparatus
This is a non-randomized, multicenter, prospective, clinical study intended to evaluate the effectiveness of a method for iontophoretic delivery of a buffered lidocaine/epinephrine solution for provision of tympanic membrane…
- Conditions
- Acute Otitis Media, Chronic Otitis Media, Recurrent Acute Otitis Media
- Trial name
- IONTO (NCT00941993)
- Testing
- Iontophoresis System (Acclarent)
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Integra LifeSciences Corporation
Otitis Media With Effusion in Children, Otitis Media Recurrent
Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT) - Study 2
The purpose of this study is to evaluate EXE844 plus tympanostomy tubes compared to tympanostomy tubes only based on sustained clinical cure at end-of-therapy (EOT).
- Trial name
- NCT02436304
- Testing
- EXE844 Sterile Otic Suspension, 0.3%, Tympanostomy Tube Insertion
- Volunteers
- 404 people
- Sponsor
- Alcon Research