Clinical trials: Otitis Media With Effusion
Hearing Loss, Sensorineural, Hearing Loss, Conductive
Wide Frequency Band Test of Hearing in Veterans
The accurate assessment of auditory status is critical for planning treatment for Veterans with hearing loss to include medical and audiological management.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Conductive, Hearing Loss, Mixed Conductive-Sensorineural, Otosclerosis
- Trial name
- CWTBAFV (NCT02019888)
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Otitis Media With Effusion
Acupuncture Effect on Inflammatory Markers in Pediatric Otitis Media With Effusion: A Pilot Study
Objective: to evaluate acupunctures effect on inflammatory markers in pediatric Otitis Media with Effusion Methods: 100 Children with otitis media with effusion (OME) diagnosis, who are in watchful waiting for 3 month, will be…
- Trial name
- NCT02215681
- Testing
- acupuncture
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Ziv Hospital
Otitis Media With Effusion
OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
The purpose of this study is to confirm the effectiveness, safety and tolerability of OTO-201 in the treatment of pediatric subjects with bilateral middle ear effusion who require tympanostomy tube placement.
- Trial name
- NCT01949155
- Testing
- OTO-201
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Otonomy, Inc.
Otitis Media With Effusion in Children, Otitis Media Recurrent
Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT)
The purpose of this study is to evaluate EXE844 plus tympanostomy tubes compared to tympanostomy tubes only based on sustained clinical cure at end-of-therapy (EOT).
- Trial name
- NCT02432105
- Testing
- EXE844 Sterile Otic Suspension, 0.3%, Tympanostomy Tube Insertion
- Volunteers
- 470 people
- Sponsor
- Alcon Research
Otitis Media
Long-term Antibiotics for Treatment and Prevention of Otitis Media in Aborignal Children
This clinical trial was conducted in a population where tympanic membrane perforation occurs in 60% infants in the first year of life.
- Trial name
- COMIT1 (NCT00539149)
- Testing
- Amoxycillin
- Where
- Australia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Otorrhea, Otitis Media With Effusion in Children
Otiprio Versus Ciprodex Tympanostomy Tube Outcomes
Otolaryngologists routinely administer ear drops at the time of tympanostomy tube placement in order to prevent tube otorrhea; however, there is a lack of consensus as to which drops are the most effective, and whether a…
- Trial name
- NCT03347461
- Testing
- Otiprio, Ciprodex
- Where
- United States
- Sponsor
- Boston Medical Center
Secretory Otitis Media
A Comparison of Surgical and a New Non-Surgical Treatment Methods for Secretory Otitis Media in Children
Secretory otitis media (SOM) or middle ear effusion is a common finding affecting children in the age of 4-5 years. It is usually associated with 5-15 deci Bells hearing loss.
- Trial name
- NCT02546518
- Testing
- Moniri Otovent, Tympanostomy tube in the ear drum
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Vastra Gotaland Region
Otitis Media With Effusion
Sinuclean Nebules 45 for Treatment of Pediatric Exudative Otitis Media
The goal of the study is to investigate if the active agent of Sinuclean Nebules is efficacious in the treatment of pediatric exudative otitis media, comparing with saline.
- Trial name
- NCT02858388
- Testing
- Sinuclean Nebules 45, Saline solution
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Galsor S.r.l.
Otitis Media, Otitis Media Chronic
SWIR Otoscopy Study
The aim of this study is to provide preliminary data to support future studies to demonstrate that the short wave infrared (SWIR) otoscope is a better diagnostic tool than a white light otoscope for diagnosing middle ear…
- Conditions
- Otitis Media, Otitis Media Chronic, Otitis Media Effusion
- Trial name
- NCT06944795
- Testing
- SWIR device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Bilateral Middle Ear Effusion Requiring Tympanostomy Tube Placement
OTO-201 for Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
The purpose of this study is to describe the safety and tolerability of two dose levels of OTO-201, placebo and sham when administered intra-operatively in pediatric subjects with bilateral middle ear effusion who require…
- Trial name
- NCT01755286
- Testing
- OTO-201
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Otonomy, Inc.
Otitis Media, Middle Ear Effusion
Clinical Study of Solo Tympanostomy Tube Device (TTD)
This is a multi-centre, single arm study to evaluate the placement of tympanostomy tubes with the AventaMed Solo Tympanostomy Tube Device (TTD)
- Trial name
- NCT02957578
- Testing
- Solo TTD
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Otitis Media With Effusion
A Clinical Trial of Proton Pump Inhibitors to Treat Children With Chronic Otitis Media With Effusion
This study is being done to see if reflux of stomach fluid might be a cause of chronic fluid in the ears. Our hypothesis is that treatment with an anti-reflux medication (lansoprazole) will increase the rate of resolution of…
- Trial name
- NCT00546117
- Testing
- lansoprazole
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Washington University School of Medicine
Microplastics, Otitis Media With Effusion
Microplastics in Otitis Media With Effusion Material
Microplastic rate is increasing ib athmosphere. They can be found in lung, kidney, heart, even placenta. Otitis media with effusion (OME) is a clinical condition that is ver common in children.
- Conditions
- Microplastics, Otitis Media With Effusion, Biofilms
- Trial name
- NCT06316635
- Testing
- ventilation tube insertion
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kerem Kökoğlu
Otitis Media in Children, Chronic Otitis Media With Effusion
Posterior vs. Anterior Tympanostomy Tube Placement
The goal of this randomized clinical trial is to compare the results of ear tube placement in two different parts of the ear drum. The ear drum can be divided into four parts (called quadrants).
- Conditions
- Otitis Media in Children, Chronic Otitis Media With Effusion, Recurrent Acute Otitis Media
- Trial name
- NCT06191562
- Testing
- Tympanostomy tube
- Where
- 2 sites in United States
- Volunteers
- 386 people
- Sponsor
- David Chi, MD
Otitis Media Effusion
Balloon Dilation of Eustachian Tube Versus Tympanostomy Tube in Management of Pediatric Obstructive Eustachian Tube Dysfunction
The study was conducted in children with otitis media with effusionto compare the efficacy and outcome of Balloon dilation of Eustachian tube versus tympanostomy tube .
- Trial name
- NCT07899177
- Testing
- eustachian tube dilatation, tympanostomy tube insertion
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Mansoura University
Hearing Loss, Conductive
Testing a New App for Children With Glue Ear
To assess whether children with glue ear ( and some normal hearing controls) and their families find the Hear Glue Ear application acceptable and easy to use.
- Trial name
- NCT06256081
- Testing
- Hear Glue ear application
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Tamsin Brown
Otitis Media With Effusion in Children, Otitis Media Recurrent
Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT) - Study 2
The purpose of this study is to evaluate EXE844 plus tympanostomy tubes compared to tympanostomy tubes only based on sustained clinical cure at end-of-therapy (EOT).
- Trial name
- NCT02436304
- Testing
- EXE844 Sterile Otic Suspension, 0.3%, Tympanostomy Tube Insertion
- Volunteers
- 404 people
- Sponsor
- Alcon Research
Otalgia, Otitis Media
Validating and AI Software for Assessment of Children With Ear Concerns
The goal of this observational study is to determine if the Glimpse machine learning algorithm can accurately assess ear diseases in children.
- Conditions
- Otalgia, Otitis Media, Otitis Media Effusion
- Trial name
- NCT07243093
- Volunteers
- 658 people
- Sponsor
- Glimpse Diagnostics, Inc.
Otitis Media Acute, Otitis Media Effusion
Gamified Training and AI Support for Improving Ear Infection Diagnosis in Primary Care
Acute otitis media (AOM), or middle ear infection, is one of the most common childhood infections and a leading cause of antibiotic prescribing in primary care.
- Trial name
- NCT07246551
- Testing
- AOM Dx Trainer (gamified educational program), No Intervention - Standard Care
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Otitis Media With Effusion
Secretory Otitis Media in Adenoids Hypertrophy Patients
This study aims to compare the fate of Secretory Otitis Media in patients with adenoids hypertrophy undergoing Adenoidectomy alone or with Myringotomy or with Myringotomy and Tympanostomy Tube application
- Trial name
- NCT04584073
- Testing
- Adenoidectomy alone or with Myringotomy or with Myringotomy and Tympanostomy Tube application
- Volunteers
- 150 people
- Sponsor
- Assiut University