Clinical trials: Otolaryngology
Thyroid
LumaENT and Patient Satisfaction
Patient satisfaction is an important metric currently used to rate quality of healthcare in hospitals. Maximizing patient satisfaction scores is therefore significantly beneficial to any hospital establishment.
- Trial name
- NCT02611622
- Testing
- LUMA ENT™, Survey
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Washington University School of Medicine
Extraesophageal Symptoms, Cough
Screening for Barrett's Esophagus in Otolaryngology Patients
The purpose of this project is to develop an accurate method to identify patients that suffer from acid reflux, but may not present with classic reflux symptoms (such as heart burn).
- Conditions
- Extraesophageal Symptoms, Cough, Throat Clearing, Hoarseness
- Trial name
- SCE (NCT00695227)
- Testing
- Screening for Barrett's Esophagus
- Where
- United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Tinnitus
Task-Based Functional MRI (fMRI) in Patients With Severely Bothersome Tinnitus
Tinnitus is a poorly understood symptom that is often described either as ringing, clicking, ocean sounds, or nature sounds. There is no cure for tinnitus.
- Trial name
- NCT01172262
- Testing
- MRI
- Sponsor
- Washington University School of Medicine
Hearing Loss, Age-Related, Presbycusis
Optimizing Elderly Hearing Loss Care in Hong Kong A Cost-Effectiveness and Satisfactory Analysis of a Pilot Collaborative Model Between Otorhinolaryngologists and Family Medicine Specialists
This study will evaluate a new collaborative elderly hearing-loss service in Hong Kong. The service is based in Family Medicine (FM) and supported by Ear, Nose and Throat (ENT) specialist nurses and audiology services.
- Trial name
- NCT07782177
- Where
- Hong Kong
- Volunteers
- 500 people
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Chronic Tonsillitis, Tonsillar Hypertrophy, Tonsillitis
Comparing Two Agents Used to Stop Bleeding During Tonsil Removal Surgery: Adrenaline Versus Hydrogen Peroxide
The goal of this quasi-experimental study is to compare the effectiveness of topical adrenaline and 3% hydrogen peroxide for controlling bleeding (hemostasis) during tonsil removal surgery in patients aged 5 to 18 years.
- Conditions
- Chronic Tonsillitis, Tonsillar Hypertrophy, Tonsillitis, Tonsillectomy
- Trial name
- NCT07675278
- Testing
- Adrenaline, Hydrogen Peroxide
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Rawalpindi Medical College
Anesthesia
Prediction of Hemodynamic Reactivity During General Anesthesia Using Analgesia/Nociception Index (ANI)
The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing ear-nose-throat or lower limb orthopedic surgery on…
- Trial name
- NCT01839513
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hôpital Edouard Herriot
Hearing Loss
SSNHL in Head & Neck Cancer Patients
A sound dosimeter will be used to measure noise level to which a population of head and neck patients on the otolaryngology ward are exposed to. The device is the EXTECH 407764 type II sound level meter (IEC 651 RS232).
- Trial name
- NCT04609982
- Testing
- ear plugs
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Carcinoma
Evaluation of the Oncoral® Test in Epidermoid Carcinomas of the Upper Aerodigestive Tract
This is a multicentric feasibility study aimed to evaluate the Oncoral® test. The study includes 2 steps. The first one aims to validate the algorithm defined at the time when the test was developed in patients with different…
- Trial name
- NCT01361100
- Testing
- Oncoral® test
- Where
- 8 sites in France
- Volunteers
- 485 people
- Sponsor
- Centre Leon Berard
Airway Remodeling, Radiography in Otolaryngology
Effect of Lateral Positions on the Shape of Upper Airway
The severity and frequency of respiratory events is increased in the supine body posture compared with the lateral position in emergency, difficult airway patients.
- Conditions
- Airway Remodeling, Radiography in Otolaryngology, Position, Patency
- Trial name
- NCT06236971
- Testing
- MRI scanning first at supine position and then turn into lateral position
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Pain Management
Local Anesthesia for Facial Fractures
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics.
- Trial name
- LAFF (NCT06429501)
- Testing
- Bupivacaine/Epinephrine, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Squamous Cell Carcinoma of the Head and Neck
Understanding GRID Radiation Therapy Effects on Human Tumor Oxygenation and Interstitial Pressure to Increase Translation of Solid Tumor Therapy
To estimate the mean and standard deviation (SD) of the post-treatment decreases in the interstitial fluid pressure and hypoxia-specific PET-scan signal from GRID-treated tumors in patients with locally advanced squamous-cell…
- Trial name
- NCT01967927
- Testing
- 18F-MISO
- Where
- United States
- Sponsor
- University of Arkansas
Rehabilitation, Neck Cancer
Rehabilitation Nursing Program in Otolaryngology
The European Commission's current political guidelines demonstrate into a joint plan aimed at improving and controlling cancer disease. Head and neck cancer (HNC) are the sixth most common cancer worldwide.
- Conditions
- Rehabilitation, Neck Cancer, Otorhinolaryngologic Neoplasms
- Trial name
- NCT05246891
- Testing
- rehabilitation nursing
- Where
- Portugal
- Volunteers
- 151 people
- Sponsor
- University of Évora
Head and Neck Cancer, Analgesia
Multimodal Pain Study in Free Flap Patients
This study will be a randomized, prospective study comparing Pain Management Arm A and Pain Management Arm B. Arm A will have scheduled Tylenol with opioids available as needed (PRN) in the peri-operative period.
- Trial name
- NCT04246697
- Testing
- Tylenol, Oxycodone, Morphine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Endoscopic Coblation Adenoidectomy
Coblation and Traditional Adenoidectomy: A Comparative Study
Adenoidectomy is a common pediatric otolaryngologic procedure. While cold curettage remains widely practiced, endoscopic coblation has been developed to enhance precision, minimize intraoperative complications, and reduce…
- Trial name
- NCT07417007
- Testing
- Cold Curettage Adenoidectomy, Coblation-Assisted Adenoidectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Medipol University
Anesthesia, Complication
Effect of Neutrophil Lymphocyte-platelet Lymphocyte Ratio on Complications in Pediatric Patients
The aim of this study was to investigate the relationship between NLR, PLR and postoperative complications in children undergoing adenotonsillectomy and adenoidectomy.
- Trial name
- NLOPEDI (NCT03756909)
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Obstructive Sleep Apnea of Child
Surgical Treatment of Children With OSA and Small Tonsils or Down Syndrome
The purpose of this study is to prospectively compare the effectiveness of a novel personalized approach to the surgical treatment of obstructive sleep apnea (OSA) in children, drug induced sleep endoscopy (DISE) directed surgery…
- Trial name
- NCT05154214
- Testing
- Adenotonsillectomy, Drug-induced sleep endoscopy directed surgery
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Hearing Loss, Adult-Onset, Tinnitus
AI-assisted Diagnosis, Triage and Assessment of Hearing Loss and Tinnitus
Hearing loss affects approximately 11 million people in the UK, while tinnitus impacts around 7 million. Both conditions can significantly reduce quality of life and are linked to poorer mental health and employment challenges.
- Trial name
- NCT07586098
- Testing
- Artificial Intelligence (AI) Assisted Clinical Decision Support Tool for managing Hearing Loss and Tinnitus
- Where
- United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- Royal Cornwall Hospitals Trust
Sinus Disease, Rhinitis
Virtual Reality Induced Analgesia for Nasal Procedures
In-office nasal procedures can cause pain and discomfort to otolaryngology patients. While local anesthesia is the mainstay choice for main management, patients may have allergies or contraindications to the anesthetic agents…
- Conditions
- Sinus Disease, Rhinitis, Turbinate; Hypertrophy Mucous Membrane, Deviated Nasal Septum Acquired
- Trial name
- NCT06812676
- Testing
- Virtual Reality Goggles
- Where
- Saudi Arabia
- Volunteers
- 64 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Tinnitus
Oto Smartphone App in Treating Tinnitus Amongst Adult Patients Compared with Standard Talking Therapies
A study that looks at treating tinnitus and its associated burden, insomnia and quality of life effects with a smartphone app when compared with the talking therapies already offered on the national health service.
- Trial name
- NCT06623123
- Testing
- Oto Smartphone Application (Oto Health Ltd), Tinnitus Retraining Therapy (TRT)
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- East and North Hertfordshire NHS Trust
Substance Withdrawal Syndrome
Process Evaluation Standardised Nurse-led Approach for Risk Screening and Decrease of Alcohol Withdrawal in ENT
In ear, nose, throat (ENT) and jaw surgery departments, up to 60% of patients suffer from alcohol dependence (Allen et al., 2009), and may develop an alcohol withdrawal syndrome (AWS) when undergoing sur-gery.
- Trial name
- NCT02782156
- Testing
- Process evaluation
- Where
- Switzerland
- Volunteers
- 89 people
- Sponsor
- University Hospital, Basel, Switzerland