Clinical trials: Otorhinolaryngologic Diseases
Hearing Loss
Bilateral Cochlear Implant Benefit in Young Children
The primary purpose of this study is to track patient outcomes for bilateral cochlear implant recipients in a cohort of 60 children, ages 12 to 36 months at time of surgery, who receive two implants in the same operation or in…
- Trial name
- NCT00424307
- Testing
- HiResolution Bionic Ear System
- Where
- 14 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Advanced Bionics
Otitis Externa, Otorhinolaryngologic Diseases
Safety and Efficacy Study of Foam Otic Cipro Compared to a Standard Solution ( Ciloxan - Alcon Labs ) to Treat Acute Otitis Externa
The purpose of this study is to assess the Safety and Efficacy of Foam Otic Cipro, a novel medication developed to treat Acute Diffuse Otitis Externa of bacterial origin.
- Conditions
- Otitis Externa, Otorhinolaryngologic Diseases, Ear Diseases, Otitis
- Trial name
- NCT00872209
- Testing
- 0.3% Ciprofloxacin Ear Drops, 0.3% Ciprofloxacin Foam Otic Cipro
- Where
- 4 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Otic Pharma
Upper Respiratory Tract Infections, Pharyngitis
Efficacy and Safety of L. Plantarum and P. Acidilactici in Children With Upper Respiratory Tract Infections
Randomized, placebo-controlled trial to evaluate the coadjuvant effect of a combination of L. plantarum and P. acidilactici probiotic strains, taken twice daily, in children 6 months to 5 years-old with upper respiratory tract…
- Conditions
- Upper Respiratory Tract Infections, Pharyngitis, Tonsillitis
- Trial name
- NCT05279534
- Testing
- Probiotic
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- AB Biotics, SA
Dysphonia, Connective Tissue Disease
Characterization of "Bamboo" and Other Vocal Cord Lesions Responsible for Dysphonia in Patients With Systemic Autoimmune Diseases (BAMBOO)
The goal of this multicenter retrospective observational study is to provide an inventory of the specific and non specific cord vocal lesions that can cause dysphonia in patients with systemic autoimmune diseases.
- Conditions
- Dysphonia, Connective Tissue Disease, Vasculitis
- Trial name
- BAMBOO (NCT06779799)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Dysphagia, Oral Phase, Temporomandibular Disorders
Efficacy of the Myofunctional Therapy on Oral Dysphagia
The aim of the study is to analyze the effects of orofacial myofunctional therapy (OMT) on oral dysphagia (OD) in patients with temporomandibular disorders (TMD).
- Trial name
- NCT04636606
- Testing
- Home Exercise, Manual Therapy Combined with Home Exercise, Orofacial Myofunctional Therapy combined with Manual Therapy and Home Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hasan Kalyoncu University
Perennial Allergic Rhinitis (PAR)
Effectiveness of Beclomethasone Dipropionate Nasal Aerosol for Perennial Allergic Rhinitis
This study will be a prospective observational study of "real world" BDP nasal aerosol users with PAR, with or without seasonal allergic rhinitis (SAR).
- Trial name
- BALANCE (NCT01632540)
- Testing
- Beclomethasone Dipropionate (BDP) Nasal Aerosol
- Where
- 46 sites in United States
- Volunteers
- 824 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Nasopharyngeal Carcinoma
Adjuvant Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
The purpose of this study is to compare concurrent chemoradiotherapy plus adjuvant chemotherapy with concurrent chemoradiotherapy in patients with locoregionally advanced NPC, in order to evaluate the value of adjuvant…
- Trial name
- NCT00677118
- Testing
- Cisplatin,fluorouracil, Cisplatin
- Where
- China
- Volunteers
- 506 people
- Sponsor
- Sun Yat-sen University
Head and Neck Cancer, Oropharyngeal Cancer
Role of Immune Activation in Response of Head and Neck Squamous Cell Carcinoma to Therapy
The purpose of this study is to investigate the role of the immune system in the response of squamous cell cancers of the head and neck to treatment that includes radiation therapy.
- Conditions
- Head and Neck Cancer, Oropharyngeal Cancer, Human Papillomavirus, Squamous Cell Cancer
- Trial name
- NCT01358097
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Mutational Falsetto, Dysphonia
Efficacy of Kinesio Taping on Mutational Falsetto
This study aimed to assess of efficacy of the kinesio-taping on male patients suffering from mutational falsetto
- Trial name
- NCT04729660
- Testing
- Kinesio Tex Gold
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Otitis Media With Effusion, Probiotics
Effect of Probiotics on Nasopharyngeal Microbiome of Children With Otitis Media With Effusion
The aim of this study is to investigate whether the microbiota in the upper respiratory tract (nasopharynx, adenoids and middle ear fluid) of otitis media with effusion (OME) patients is changed after 4 weeks of probiotic product…
- Conditions
- Otitis Media With Effusion, Probiotics, Adenoid Vegetations
- Trial name
- NCT03277820
- Testing
- Probactiol Mini
- Where
- Belgium
- Volunteers
- 37 people
- Sponsor
- University Hospital, Antwerp
Dysphagia, Head and Neck Cancer
Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Conditions
- Dysphagia, Head and Neck Cancer, Mucositis, Xerostomia
- Trial name
- NCT00503776
- Testing
- exercise intervention, amifostine trihydrate, therapeutic dietary intervention
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Alzheimer Disease, Dementia
HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms
This randomized controlled trial study aims to evaluate a revised hearing care intervention for older adults with Alzheimer's Disease and Related Dementias (ADRD).
- Conditions
- Alzheimer Disease, Dementia, Hearing Loss, Cognitive Impairment
- Trial name
- HEARS-NPS (NCT06930560)
- Testing
- HEARS-NPS device, HEARS-NPS program
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hearing Loss
Hearing Preservation Using Dexamethasone and Hyaluronic Acid for Cochlear Implantation
The objective of the present study is to investigate the effect dexamethasone and hyaluronic acid have on hearing preservation
- Trial name
- NCT01588925
- Testing
- Cochlear Implantation, Cochlear Implantation+dexamethasone, Cochlear Implantation+dexamethasone+hyaluronic acid
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- University of Sao Paulo General Hospital
Vestibular Disorder
Comparative Effects Of Gaze Stability Exercises And Optokinetic Exercises In Patients With Vestibular Hypofunction
This randomized clinical trial will occur at Bahawal Victoria Hospital, Bahawalpur within 7 months after the approval of synopsis. The sample size for this trial will be 40 participants.
- Trial name
- NCT06303310
- Testing
- Gaze Stability Exercises, Optokinetic Exercises, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Nasal Polyps
Omalizumab Efficacy in Patients With Refractory Nasal Polyps
in patients with chronic rhinosinusitis with nasal polyps and concomitant asthma, they have a poor therapeutic response and a higher recurrence rate, and treatment in these patients often fails.
- Trial name
- NCT05405478
- Testing
- Omalizumab, SNOT22 score
- Where
- Iran
- Volunteers
- 2 people
- Sponsor
- Shiraz University of Medical Sciences
Vestibular Diseases, Vestibular Vertigo
Investigation of the Efficacy of Non-Invasive Vagus Nerve Stimulation and Physiotherapy in Unilateral Vestibular Hypofunction Patients
The purpose of this study: To investigate the effectiveness of non-invasive vagus nerve stimulation and vestibular rehabilitation applications in patients diagnosed with Unilateral Vestibular Hypofunction (UVH).
- Conditions
- Vestibular Diseases, Vestibular Vertigo, Vertigo
- Trial name
- NCT06332326
- Testing
- non-invasive vagus nerve stimulation, vestibular rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Nasopharyngeal Carcinoma
KSD-101 Therapy for Standard Treatment Failed EBV-associated NPC: an Exploratory Clinical Trial
The main purpse of this study is to evaluate the safety of KSD-101 in patients with EBV-associated Nasopharyngeal Carcinoma,to evaluate the initial clinical outcomes and evaluate the immune response to KSD-101 for the treatment…
- Trial name
- NCT06370026
- Testing
- KSD-101
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Patient Satisfaction, Relapse
Long-term Follow-up After Surgical Treatment for GERD (Gastroesophageal Reflux Disease)
10 years of follow-up with SF-36 global (Quality of Life issues), GSRS (Gastrointestinal Symptom Rating Scale) and two reflux specific questionnaires.
- Conditions
- Patient Satisfaction, Relapse, Dysphagia, Bloating
- Trial name
- NCT04182178
- Testing
- 10 years follow up
- Where
- Sweden
- Volunteers
- 307 people
- Sponsor
- Karolinska Institutet
Allergic Rhinitis
Effect of Home Environment Regulation on Symptom Control and Quality of Life in Children With Allergic Rhinitis
The purpose of this study is to examine the effect of nursing intervention to regulate the home environment on symptom control and quality of life in children with allergic rhinitis.
- Trial name
- NCT04479085
- Testing
- nursing intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Head and Neck Cancer
S0329, Gemcitabine and Paclitaxel in Treating Patients With Persistent, Recurrent, or Metastatic Head and Neck Cancer
RATIONALE: Drugs used in chemotherapy, such as gemcitabine and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00100789
- Testing
- gemcitabine, paclitaxel
- Where
- 123 sites in United States
- Volunteers
- 67 people
- Sponsor
- SWOG Cancer Research Network
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