Clinical trials: Outcomes
Aged, Home Care, Hospital-Based
Home-based Acute Care for Older Persons Initiated by the Emergency Medical and Ambulance Services - a Retrospective Observation of Effects on Healthcare Utilisation and Mortality
This observational study aims to examine outcomes of home-based acute care delivered by a mobile healthcare team in persons aged 75 years and older following an episode of acute illness.
- Conditions
- Aged, Home Care, Hospital-Based, Home Care Services, Emergency Medical Dispatch Centre
- Trial name
- NCT07472335
- Testing
- Type of care pathway
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Vastra Gotaland Region
Breast Cancer, Patient Reported Outcomes
Breast Cancer Patient Engagement With Patient Reported Outcome Measure Survey
The purpose of this research protocol is to measure Patient Reported Outcome Measures (PROMs) in breast cancer patients. PROM results will be provided to patients and providers and the investigators will evaluate the relationship…
- Trial name
- NCT03995082
- Testing
- Patient Reported Outcome Measure Survey result feedback
- Where
- 3 sites in United States
- Volunteers
- 925 people
- Sponsor
- University of Colorado, Denver
Cancer, Abdominal Cancer Surgery
Developing Pilot Postoperative Guidelines for Improved Functional Outcomes After High-Risk Cancer Surgery
The objective of this study is to develop and evaluate the implementation of novel timeline-specific National Comprehensive Cancer Network (NCCN)-style clinical guidelines designed to improve functional outcomes after high-risk…
- Conditions
- Cancer, Abdominal Cancer Surgery, Surgery, Recovery Outcomes
- Trial name
- NCT07720089
- Testing
- Algorithmic Guideline for Functional Recovery following Cancer Surgery
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Alabama at Birmingham
Maternal Health, Pregnancy Outcomes
Antenatal and Postnatal Care Research Collective - Household Survey (ARCH)
The overarching goal of the ARCH Survey is to establish a prospective longitudinal pregnancy surveillance study in Lusaka, Zambia, to precisely characterize the pregnancy rate and outcomes of women of reproductive age prior to…
- Trial name
- ARCH (NCT05154331)
- Where
- Zambia
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Breastfeeding, Breastfeeding Attitudes
Breastfeeding Education Integrated With Web Portal and Mobile Application-Supported Counseling
Breastfeeding provides significant benefits for maternal and infant health; however, perceived insufficient milk supply is one of the most common factors associated with early breastfeeding discontinuation.
- Conditions
- Breastfeeding, Breastfeeding Attitudes, Breastfeeding Education, Breastfeeding Initiation
- Trial name
- NCT07721311
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pregnancy in Diabetes, Pregnancy
Are There Any Clinical Benefits to Screening for Late -Onset Gestational Diabetes Mellitus?"
This study aims to screen women who have a negative Gestational diabetes mellitus (GDM) result in routine screening tests or who have never had it with the Fasting Blood Glucose Test (FBG) at 32-34 weeks of gestation to diagnose…
- Conditions
- Pregnancy in Diabetes, Pregnancy, Pregnancy Outcomes
- Trial name
- NCT07776314
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Izmir Ataturk Training and Research Hospital
Mobility on the Way to Work and Health-related Outcomes
Promoting Sustainable and Active Mobility Among Employees and Students
The aim of the study is to assess health data (heart rate variability, blood pressure, blood glucose, particulate matter pollution) and travel characteristics (length, duration and type of commute) on the way to and from work…
- Trial name
- DiNaMo-active (NCT06493006)
- Where
- Germany
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Infertility (IVF Patients), BMI
BMI Versus Body Fat Percentage - Which is the Better Predictor of Fertility Outcomes in IVF Cycles?
The goal of this prospective observational cohort study is to evaluate whether body composition measured using bioelectrical impedance analysis (BIA) (including measures of body fat% and visceral fat) serve as a better predictor…
- Conditions
- Infertility (IVF Patients), BMI, Bioelectrical Impedance Analysis, IVF Outcomes
- Trial name
- NCT07765368
- Testing
- Measurement of BIA (Body Fat and Visceral Fat Percentage)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Nutrition Assessment, Nutritional Support
The Effect of Perioperative Nutritional Assessment and Nutritional Support on Clinical Outcomes
It is a study to evaluate the relationship between preoperative nutritional assessment and clinical outcomes and to explore the effect of preoperative nutritional support on clinical outcomes in patients after abdominal operation.
- Conditions
- Nutrition Assessment, Nutritional Support, Clinical Outcomes, General Surgery
- Trial name
- PNAS (NCT03115931)
- Testing
- no intervention
- Where
- China
- Volunteers
- 4,880 people
- Sponsor
- Jinling Hospital, China
Tracheostomy Patients, Multidisciplinary Care Team
Evaluation of a Specialised Tracheostomy Team for the Management of Patients With a Tracheostomy Cannula in a Belgium General Hospital: A Retrospective Study.
Patients admitted to intensive care units (ICUs) frequently require prolonged mechanical ventilation. Difficulties in weaning from mechanical ventilation represent an important indication for performing a tracheotomy, which…
- Conditions
- Tracheostomy Patients, Multidisciplinary Care Team, Outcomes, Hospital
- Trial name
- NCT07755969
- Testing
- The implementation of the specialised multidisciplinary tracheostomy team.
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Vitaz
an Intelligent Teaching Agent for the "Epidemiology" Course of the MBBS Program, Students' Critical Thinking, Practical Ability and Learning Outcomes
Research and Application of an AI Agent-Based MBBS Course Assistant
Prior to the quasi-experiment, this study performed semi-structured interviews among Bachelor of Medicine and Bachelor of Surgery(MBBS) undergraduate students from the Belt and Road International Medical College, Zhejiang…
- Trial name
- NCT07752160
- Testing
- Socratic Agent for Guided Epidemiology, General LLM
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Malocclusion, Angle Class II, Overbite (Excessive) Horizontal
Long-term Stability of Treatment With the Twin Block Appliance
The objective of this observational study is to investigate the long-term stability of treatment with the Twin block appliance in a patient group previously treated with a Twin block appliance.
- Conditions
- Malocclusion, Angle Class II, Overbite (Excessive) Horizontal, Overbite (Excessive) Deep, Treatment Outcome
- Trial name
- NCT07752498
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Region Jönköping County
Preeclampsia Postpartum, Adverse Pregnancy Outcomes
A Community Health Worker Intervention to Address Adverse Pregnancy Outcomes
United States maternal mortality and preterm birth rates are among the highest among high-income countries due in part to a combination of racial, regional and socioeconomic disparities in access to care and overall health.
- Trial name
- AW2H (NCT06353256)
- Testing
- usual postpartum care, usual postpartum care + community health worker intervention
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Surgery, Obstructive Defecation Syndrome
Mental Health Outcome After Surgery for Obstructed Defecation Syndrome (ODS)
Background: Obstructed Defecation Synsdrome (ODS) causes people to strain and sometimes need help to go to the toilet. They think about going to the toilet a lot, which makes their lives worse.
- Conditions
- Surgery, Obstructive Defecation Syndrome, Mental Health Issue, Depression/Anxiety
- Trial name
- MentODSSurg (NCT06502184)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Evangelisches Klinikum Köln Weyertal gGmbH
Major Bleeding, Major Bleeding Outcomes
Observational Study to Characterize Patients Experiencing Major Acute Bleeding Events During Anticoagulation Treatment With Oral Factor Xa Inhibitors.
Oral factor Xa inhibitors are widely used for the prevention of cardioembolic events in patients with atrial fibrillation and for the treatment of venous thromboembolism, thanks to their good efficacy/safety ratio compared to…
- Trial name
- EMERALD (NCT07745933)
- Where
- Italy
- Volunteers
- 503 people
- Sponsor
- Fadoi Foundation, Italy
Psychosocial Functioning, Surgery
Building Resilience for Surgical Recovery
The goal of this clinical trial is to test problem solving therapy (PST) in older adults who are undergoing major surgery. The main question it aims to answer is: What is the feasibility and acceptability of delivering PST to…
- Conditions
- Psychosocial Functioning, Surgery, Older Adults, Physical Function
- Trial name
- BRSR (NCT06174701)
- Testing
- Problem Solving Therapy (PST), Enhanced Usual Care
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Osteopathic Medicine
Examining Relationships Between Musculoskeletal Function Measurements of Movement Efficiency and Nervous System Function After Chronic Stroke
Stroke remains the leading cause of severe disability, and survivors frequently have incomplete recovery. More than half of older survivors have impaired mobility which contributes to poorer quality-of-life (QoL) and suffering.
- Conditions
- Stroke, Osteopathic Medicine, Physical Examination, Heart Rate Variability (HRV)
- Trial name
- SOMADC-CC (NCT07737873)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Quality of Life Outcomes
Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials
Although cure rates continue to rise, one in five children with cancer still die from their disease, so new therapies are urgently needed.
- Trial name
- NCT07696065
- Testing
- Pediatric Palliative Care Consultation
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Phoenix Children's Hospital
Elderly, Surgery
Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery
A majority of the elderly patients undergo surgery for malignant tumors. For these patients, postoperative tumor recurrence and metastasis are main factors that worsen long-term outcomes.
- Conditions
- Elderly, Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03012971
- Testing
- Dexmedetomidine supplemented morphine analgesia, Morphine analgesia
- Where
- 12 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Peking University First Hospital
Sarcopenia in Elderly, Sarcopenia
Effect of the Consumption of Cookies Enriched With Plant Proteins and of a Vitamin D Supplement on the Progression of Sarcopenia in the Elderly
The ageing population makes it necessary to find effective strategies for the prevention of sarcopenia (the progressive loss of muscle mass and strength and a decline in physical performance) that can be counteracted with foods…
- Conditions
- Sarcopenia in Elderly, Sarcopenia, Nutritional Intervention, Microbiome Analysis
- Trial name
- SARC-PEA (NCT07356440)
- Testing
- Vitamin D3 supplement, Protein-enriched biscuits, Control biscuit
- Where
- 3 sites in Italy
- Volunteers
- 74 people
- Sponsor
- University of Udine