Clinical trials: Outcomes
Malalignment, Bone, Osteoarthritis, Knee
Knee Osteotomy Associated With Allograft Meniscus Transplantation
This is a prospective randomized double-blind controlled clinical trial with parallel arms and 1:1 allocation. The main objective of the BIOMAT project is to demonstrate, through an RCT, whether the combined approach by knee…
- Trial name
- NCT05840887
- Testing
- Knee osteotomy associated with meniscal allograft transplantation, Knee osteotomy
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Istituto Ortopedico Rizzoli
Insomnia
Evaluation of Digital Sleep Program to Improve Sleep Among New Parents
Sleep disturbances are highly prevalent during the postpartum period, with an estimated 40-60% of new parents experiencing inadequate sleep.
- Trial name
- NCT07302893
- Testing
- Digital CBT-I
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Udisense DBA Nanit
Surgery
Evaluation of Coaching Impact on Surgical Outcomes
This two arms parallel cluster-randomized trial will evaluate the impact of a customized coaching program for surgeons on the occurrence of patient major adverse events.
- Trial name
- TopSurgeons (NCT04532658)
- Testing
- Coaching program
- Where
- France
- Volunteers
- 20,791 people
- Sponsor
- Hospices Civils de Lyon
Treatment Resistant Depression, Generalized Anxiety Disorder
An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept Assay
Genomind has developed and introduced a battery of genetic tests, the Genecept Assay, which clinicians can administer to patients using a simple saliva sample technique. The present study proposes to enroll 1.
- Trial name
- COM-1 (NCT01507155)
- Testing
- Genecept Assay
- Where
- United States
- Volunteers
- 685 people
- Sponsor
- Genomind, LLC
Osteoarthritis
Comparison of Stability and Outcomes in Single-radius Femoral Component for Total Knee Arthroplasty
This is a comparison of the functional results and Varus-Valgus Stability in Single-radius versus Multi-radius Femoral Component for Total Knee Arthroplasty.
- Trial name
- NCT01379755
- Where
- South Korea
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Chronic Migraine
rTMS for the Prevention Treatment of CM: a Single Arm Study
We design this pilot, single arm study to explore the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) for the treatment of chronic migraine.
- Trial name
- NCT03568617
- Testing
- rTMS
- Volunteers
- 15 people
- Sponsor
- Peking Union Medical College Hospital
Post-operative Pain, Post-operative Nausea and Vomiting
Multimodal Perioperative Pain Management: ComfortSafe Program
Proposed is a demonstration project to characterize the immediate, short-term and long-term pain and other post-operative outcomes of 60, self-selected breast (n=20), caesarian-section (n=20) and abdominal (n=20) surgical…
- Conditions
- Post-operative Pain, Post-operative Nausea and Vomiting, Respiratory Depression, Confusion Postoperative
- Trial name
- NCT04046068
- Testing
- ComfortSafe Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
Achilles Tendinitis
A Pilot Study: Treatment of Achilles Tendinopathy With Platelet-Rich Plasma Therapy
The overall goal of this proposal is to correlate ultrasound elastography technique with more standard clinically based outcome measures within the setting of a small sample sized group of patients affected by moderate-to…
- Trial name
- NCT01911650
- Testing
- Autologous Platelet Rich Plasma, Ultrasound Imaging, Quality of Life Questionnaires
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Sleep Circadian Rhythms, Chronodisruption
Assessing Sleep and Circadian Rhythms in Primary Brain Tumors Patients
Background: Sleep disturbances are among the most common and severe symptoms reported by people with primary brain tumors (PBT).
- Trial name
- NCT04669574
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- National Cancer Institute (NCI)
Metastatic Cancer
Electronic Patient Reporting of Symptoms During Cancer Treatment
The current study is designed to test nationally whether patients' outcomes and utilization of services can be improved through symptom monitoring via patient-reported outcomes between visits.
- Trial name
- PRO-TECT (NCT03249090)
- Testing
- Patient Self-Reporting of Symptoms, Usual Care Delivery
- Where
- 45 sites in United States
- Volunteers
- 1,197 people, healthy volunteers welcome
- Sponsor
- Alliance Foundation Trials, LLC.
Delirium
Delirium in the Emergency Department and Its Extension Into Hospitalization
Delirium occurs in 10% of older emergency department (ED) patients, yet it remains poorly understood. To date, the predominance of delirium studies have been conducted in hospitalized patients and therefore have limited…
- Trial name
- DELINEATE (NCT01651897)
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- Vanderbilt University
Acute Decompensated Heart Failure
The Association Between Visual Echocardiographic Scoring System and Clinical Outcomes in Patient With Acute Decompensated Heart Failure
This study aims to evaluate the association between visual echocardiographic scoring system (visual mitral and tricuspid = VMT score) with clinical outcome among patients with acute decompensated heart failure.
- Trial name
- VISCO-HF (NCT06586008)
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Universitas Diponegoro
One-day Training Simulation With 4 Immersive Scenarios
Comparison of Learning Outcomes Between the Roles of Learner During an Immersive Simulation
The use of simulation in medical education has been associated with positive results in the acquisition of knowledge, skills, behaviors and in patient outcome.
- Trial name
- NCT02804425
- Testing
- actor-spectator
- Where
- France
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Université Paris-Sud
Pressure Injuries, Spinal Cord Injuries (SCI)
Electrical Stimulation for Clinical and Psychosocial Outcomes in Chronic Pressure Injuries
Pressure injuries are chronic wounds that frequently occur in immobilized patients and are associated with delayed healing, reduced quality of life, and significant psychological burden.
- Conditions
- Pressure Injuries, Spinal Cord Injuries (SCI), Traumatic Brain Injury
- Trial name
- NCT07493889
- Testing
- High-Voltage Monophasic Pulsed Current Electrical Stimulation, Standard Wound Care
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Non-Alcoholic Fatty Liver Disease
Calisthenics Versus High Intensity Interval Training in NAFL
According to sample size calculation and after achieving the inclusion criteria, sixty patients with non-alcoholic fatty liver (NAFL) of both genders will be enrolled in this study and their ages will be ranged from30s-40s; they…
- Trial name
- NCT06032650
- Testing
- Calisthenics exercise and High intensity interval training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Prostate Cancer
Genetic Counseling Processes and Outcomes Among Males With Prostate Cancer (ProGen)
This randomized controlled trial aims to evaluate the impact of pre-test video education and post-test genetic counseling as compared to in-person pre-test genetic counseling in males with advanced prostate cancer.
- Trial name
- ProGen (NCT03328091)
- Testing
- Traditional pre-test genetic counseling, Pre-test video education
- Where
- 3 sites in United States
- Volunteers
- 662 people
- Sponsor
- Dana-Farber Cancer Institute
Type 2 Diabetes
Evaluation of a Single Center Expansion of Continuous Glucose Monitor Access in Patients With Type 2 Diabetes
The purpose of this pilot study is to hopefully generate interest that will lead to more robust trials evaluating FreeStyle Libre 2 sensors in patients with type 2 diabetes on any diabetes regimen.
- Trial name
- NCT05200390
- Testing
- Continuous glucose monitor
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Chieh Chen
Head and Neck Carcinoma
An Exercise Prehabilitation Intervention for Improving Mobility and Recovery Outcomes in Patients Undergoing Head and Neck Cancer Surgery
This clinical trial evaluates a prehabilitation exercise intervention for improving mobility and recovery outcomes in patients undergoing surgery for head and neck cancer.
- Trial name
- NCT06079697
- Testing
- Electronic Health Record Review, Exercise Intervention, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- OHSU Knight Cancer Institute
HIV (Human Immunodeficiency Virus), Malnutrition
Income Generation, Food and Nutrient Security for Improved Livelihoods and Health Outcomes Among HIV-Positive, Kenya
The goal of this trial is to evaluate whether cassava root and sesame seed granules combined with nutrition education can improve the nutritional status of HIV-seropositive adults.
- Trial name
- NCT07620197
- Testing
- Arm1 - Cassava root and (sesame) simsim seed granules, Nutrition education
- Where
- 2 sites in Kenya
- Volunteers
- 64 people
- Sponsor
- Maseno University
Weight Management, Disordered Eating Behaviors
GLP-1 Impacts on Weight Management
The goal of this observational study is to learn about the long-term effects of GLP-1RAs (Ozempic, Wegovy, Rybelsus, Mounjaro, or Zepbound) in adolescents and young adults aged 12-21 who will start taking this drug for weight…
- Trial name
- GLOW (NCT07829016)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco