Clinical trials: Outpatients, open to volunteers
Cancer T1-N0 or T2-N0 of the Oral Cavity
Sentinel. Ambulatory. Oral Cavity. Oropharynx (S.A.C.O)
This is a single-center pilot study of open-label, non-randomized interventional research based on the outpatient management of 30 patients with T1-N0 or T2-N0 cancer in the oral cavity or oropharynx.
- Trial name
- SACO (NCT03545256)
- Testing
- outpatient surgery for T1-N0 or T2-N0 cancers of the oral cavity or oropharynx with lymph node search
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer
Effect of Mandala Coloring on Anxiety, Distress, and Comfort in Breast Cancer Patients Receiving Outpatient Chemotherapy
Breast cancer patients receiving chemotherapy often experience psychological distress, anxiety, and discomfort during treatment. Non-drug supportive methods may help improve patients' well-being during chemotherapy.
- Trial name
- NCT07367269
- Testing
- Mandala Coloring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Artvin Coruh University
Refractive Errors
Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study)
This study aims to evaluate the SmartEyes smart refraction measurement device in two phases under real outpatient optometry room visits at Wuhan Children's Hospital.
- Trial name
- CVSP-SOMD (NCT07803094)
- Testing
- SmartEyes smart refraction measuring device, Topcon KR800, Subjective refraction
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Cardiovascular Diseases, Schizophrenia
Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psychosis or Bipolar Affective Disorder
The goal of this clinical trial is to compare the effect of nutritional counseling versus no treatment in patients with schizophenia or bipolar affective disorder.
- Conditions
- Cardiovascular Diseases, Schizophrenia, Psychosis, Bipolar Disorder
- Trial name
- NCT06197048
- Testing
- Nutritional counseling
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Vestre Viken Hospital Trust
COVID-19, SARS-CoV-2
To Evaluate SCTA01 Treatment of High-risk Outpatients With COVID-19
The study is a multicenter, adaptive, randomized, double-blinded and placebo-controlled Phase II/III clinical trial. It will be conducted at selected investigational sites globally. The study is comprised of 2 parts.
- Trial name
- MAOP3 (NCT04709328)
- Testing
- SCTA01
- Volunteers
- 690 people
- Sponsor
- Sinocelltech Ltd.
Lung Transplant, Well-Being, Psychological
A Study of Latin Dance for Post- Lung Transplant
The purpose of this research study is to see if participating in Latin dance for 12 sessions can improve wellbeing in several areas including balance, fear of movement, anxiety, depression and spirometry.
- Trial name
- NCT05924113
- Testing
- Latin Dance
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Mayo Clinic
Inflammatory Bowel Diseases, Ulcerative Colitis
Development of the SC-IBD Self-Care Measurement Scale
This study aims to develop and validate a disease-specific self-care measurement scale for patients with Inflammatory Bowel Disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- SC-IBD (NCT07494227)
- Where
- Italy
- Volunteers
- 275 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Concussion, Mild Traumatic Brain Injury, Brain Injury
Expanding Access to mTBI Treatment for Veterans and Service Members With Co-occurring Substance Use
The purpose of this research is to determine whether military veterans and service members with mild traumatic brain injury with and without co-occurring substance use can complete and benefit from integrated interdisciplinary…
- Conditions
- Concussion, Mild Traumatic Brain Injury, Brain Injury, Traumatic Brain Injury, Substance Use
- Trial name
- ExpandAccess (NCT06620900)
- Testing
- Integrated Model of Care
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Shepherd Center, Atlanta GA
Hemodialysis, Clinical Assessment
Contactless Optical Monitoring of AV Access Using the PatenSee System in Outpatient Hemodialysis Patients
This is a prospective, non-interventional, single arm, international multicenter study in which up to 120 adult participants with kidney failure requiring regular hemodialysis through arteriovenous (AV) access (AV fistula or…
- Trial name
- NCT07194395
- Testing
- PatenSee System
- Where
- 2 sites in United States, Israel
- Volunteers
- 90 people
- Sponsor
- PatenSee Ltd.
Heart Failure, Renal Disease, Chronic
Outpatient Hypertonic Saline and Loop Diuretic Combination Therapy in Cardiorenal
Congestive heart failure (CHF) remains a major cause of morbidity, rehospitalization, and mortality worldwide, particularly among elderly and polymorbid patients.
- Trial name
- SALT-HF (NCT07596329)
- Testing
- Hypertonic sodium chloride 10%, Sodium Chloride 0.9%, Furosemide intravenous solution
- Volunteers
- 60 people
- Sponsor
- University of Monastir
Endocarditis Infective
Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis
Non-inferiority trial to determine whether partial oral treatment is non-inferior to OPAT(Outpatient parenteral therapy) in patients diagnosed with infective endocarditis
- Trial name
- OraPAT-IEGAMES (NCT05398679)
- Testing
- Cefaclor, Ciprofloxacin Tablets, Ciprofloxacin Injection
- Where
- 20 sites in Spain
- Volunteers
- 360 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Staphylococcus Aureus Colonization, Surgical Site Infections
Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients
The purpose of the study is to determine the effectiveness, safety, and health-care utilization and costs of a preoperative Staphylococcus aureus (SA) screening and decolonization bundle, (5 days of nasal mupirocin ointment…
- Conditions
- Staphylococcus Aureus Colonization, Surgical Site Infections, Healthcare Associated Infections
- Trial name
- NCT06378359
- Testing
- Screening and decolonization for SA carriers with the 3 drug bundle, No screening for SA, no screening
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Minnesota
Induction of Labor Affected Fetus / Newborn
Cervical Ripening as an Outpatient Method Using the Foley (COMFORT)
A multicenter pragmatic randomized trial of nulliparous women undergoing a term (≥37 weeks) induction of labor wherein the provider intends to use a Foley catheter for cervical ripening.
- Trial name
- COMFORT (NCT05759988)
- Testing
- Outpatient Foley catheter
- Where
- 6 sites in United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Fibroid Uterus, Polyp Uterus
Comparison of Operative Hysteroscopy Performed in the Operating Room Versus Outpatient Settings
This is an observational prospective monocentric study which aims to compare operative hysteroscopies performed in the operating room under general or loco-regional anesthesia and those performed outside the operating room…
- Conditions
- Fibroid Uterus, Polyp Uterus, Retained Products of Conception
- Trial name
- NCT07146659
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Distal Radius Fracture Fixation
Same Day Discharge Vs. Hospitalization for Operative Fixation of Distal Radius Fractures
The goal of this clinical trial is to examine the results for same-day discharge after distal radius operative fixation in adult pupolation.
- Trial name
- NCT07276334
- Testing
- early release from hospital, Day after surgery release
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Assaf-Harofeh Medical Center
Insomnia, Delayed Sleep Phase Disorder
Blue-blocking Glasses for Sleep Disorders in Child and Adolescent Psychiatry
Sleep problems and regulation difficulties are frequent in the child and adolescent psychiatry population. Insomnia and delayed sleep-wake phase disorders (DSPWD) are highly prevalent, and risk factors for developing more severe…
- Conditions
- Insomnia, Delayed Sleep Phase Disorder, Hyperarousal, Transdiagnostic Psychopathology
- Trial name
- BATCAT-pilot (NCT07433491)
- Testing
- Blue-blocking glasses (BB-glasses) or real darkness from 9 p.m. to desired wake-up time + night mode setting on mobile phone, Control
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Fonna
Acute Respiratory Infection, Influenza-like Illness
Effectiveness and Implementation of a National Guideline for Acute Respiratory Tract Infections to Reduce Antibiotic Prescribing in Swiss Primary Care
The ImpProGUIDE study aims to find out whether implementing new Swiss national guidelines for acute respiratory infections (ARI) can help to reduce antibiotic prescribing in primary care.
- Trial name
- ImpProGUIDE (NCT07396428)
- Testing
- Training Session on acute respiratory infection guideline within a multifaceted implementation strategy
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis
Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient Treatment
Vaginal disorders, including vulvovaginal candidiasis (VVC), bacterial vaginosis (BV), and genitourinary syndrome of menopause (GSM), are highly prevalent conditions that significantly affect women's quality of life and sexual…
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis, Vulvovaginal Candidiasis (VVC)
- Trial name
- NCT07697768
- Testing
- Blue LED Photobiomodulation
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Patricia Lordelo
Kidney Replacement Therapy
Community Health Workers in an Interdisciplinary Outpatient CKD Clinic to Optimize Social Care Navigation, Patient Engagement, and Home Dialysis Utilization
The goal of this clinical trial is to learn if this intervention (the CHOOSE Home intervention) is feasible and may lead to more home dialysis usage in a high-risk patient population.
- Trial name
- CHOOSE Home (NCT06925776)
- Testing
- CHOOSE Home Intervention, Usual Care
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Montefiore Medical Center
Opioid Use Disorder
Measurement-Based Care to Support Buprenorphine-Naloxone Treatment in Outpatient Addiction Clinics
People receiving buprenorphine-naloxone (bup-nx) for opioid use disorder often face changes in cravings, withdrawal, and return to use risk between clinic visits, but their care team may not know about these changes until the…
- Trial name
- Bup-MBC (NCT07839182)
- Testing
- Bup-MBC
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Vanderbilt University Medical Center