Clinical trials: Ovarian Hyperstimulation Syndrome
Ovarian Hyperstimulation Syndrome
Administration of Methylprednisolone for Prevention of Ovarian Hyper Stimulation Syndrome
This study is a prospective randomized clinical controlled trial to assess the efficacy of the Methylprednisolone for preventing ovarian hyper stimulation syndrome in in vitro fertilization (IVF) cycles.
- Trial name
- NCT01014104
- Testing
- Methylprednisolone, Control
- Where
- Iran
- Volunteers
- 218 people
- Sponsor
- Royan Institute
Polycystic Ovary Syndrome, Ovarian Hyperstimulation Syndrome
In Vitro Maturation of Immature Oocytes
The aim of this study is to aspirate immature oocytes from antral follicles and mature the oocytes in vitro. These mature oocytes will serve for fertilization and the creation of embryos which will be replace in the uterus as…
- Trial name
- NCT00480337
- Testing
- In Vitro Maturation of immature oocytes
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Polycystic Ovary Syndrome, Ovarian Hyperstimulation Syndrome
The Four Methods of Ovarian Stimulation in Patients With Polycystic Ovarian Syndrome
This study is a randomized controlled clinical trial to compare the pregnancy outcomes of mild and minimal stimulation in infertile women with polycystic ovarian syndrome.
- Trial name
- NCT03876145
- Testing
- Minimal ovarian stimulation
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Coasting is one of the means to reduce the risk of OHSS for patients at risk for severe OHSS. During coasting gonadotrophin administration is withheld until serum E2 levels drop to a range considered safe.
- Trial name
- NCT01109888
- Testing
- Cetrotide
- Sponsor
- Wolfson Medical Center
Ovarian Hyperstimulation Syndrome
Calcium for Prevention of Ovarian Hyperstimulation Syndrome
There are many protocols for prevention of ovarian hyperstimulation syndrome, intravenous calcium is a novel protocol. But still there is lack of evidence of it is real effect in prevention of OHSS \& the mechanism of its action…
- Trial name
- OHSS (NCT01427335)
- Testing
- calcium, 0.9 % saline
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ovarian Hyperstimulation Syndrome
Management of Ovarian Hyperstimulation Syndrome as a State of Defective Mineralocorticoid Response
lines of evidence that support nature of ovarian hyperstimulation syndrome (OHSS) as "defective mineralocorticoid response" are cited, our hypothesis is tested clinically in both prophylaxis against and treatment of OHSS.
- Trial name
- NCT04351126
- Testing
- Fludrocortisone 0.1 Milligrams (mg), Bromocriptine
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- Ganin Fertility Center
Infertility
Resveratrol as a Preventive Treatment of OHSS
Evaluation of resveratrol treatment oh ovarian hyperstimulation syndrome in egg donors
- Trial name
- RES-OHSS (NCT03446625)
- Testing
- Resveratrol
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Ovarian Hyperstimulation Syndrome
The Effect of Human Albumin Infusion on VEGF Levels in Women at Risk for Ovarian Hyperstimulation Syndrome
This research study was designed to look at the effect of human albumin transfusion on circulating levels of Vascular Endothelial Derived Growth Factor (VEGF), a protein that is believed to be responsible for the syndrome of…
- Trial name
- NCT00617864
- Testing
- Human Albumin Infusion, Saline Infusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Polycystic Ovarian Syndrome
Letrozole Combined With Gonadotropins (Gn) for Ovarian Stimulation Undergoing in Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI) in Patients With Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine whether letrozole combined with gonadotropins are effective in the ovarian hyperstimulating for IVF/ICSI in patients with PCOS.
- Trial name
- NCT00894608
- Testing
- letrozole + gonadotropins, GnRHa + gonadotropins
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yunyang Medical College
Ovarian Hyperstimulation Syndrome
The Use of GnRH Agonist Trigger in the Prevention of OHSS
To compare the incidence of ovarian hyperstimulation syndrome (OHSS) and implantation rate between high responder patients using Gonadotropin releasing GnRH) agonist or human chorionic gonadotropin (hCG) to trigger final oocyte…
- Trial name
- NCT00349258
- Testing
- Leuprolide acetate
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Infertility
Calcium Dobesilate Versus Coasting for Prevention of Ovarian Hyperstimulation Syndrome
The purpose of this study is to compare the effect of oral Calcium Dobesilate versus costing in the prevention of ovarian hyperstimulation syndrome (OHSS) in high-risk women underwent intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT02290002
- Testing
- Calcium Dobesilate, coasting
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- khalid abd aziz mohamed
IVF, Oocyte Maturation Defect 1
IVF Outcome Following Progestogen Ovarian Stimulation
The new strategy is by using the progestogen to block the luteinizing hormone(LH) surge either endogenous during luteal phase stimulation, or exogenous in the follicular phase i.e progestin primed ovarian stimulation (PPOS).
- Conditions
- IVF, Oocyte Maturation Defect 1, Clinical Pregnancy Rate, Ovarian Hyperstimulation
- Trial name
- NCT04175990
- Testing
- Dydrogesterone Pill
- Where
- Malaysia
- Volunteers
- 155 people
- Sponsor
- National University of Malaysia
No Condition
Comparison of Clinical Outcomes Between IVM and Minimal Stimulation IVF in Patients With PCOS
Polycystic ovarian syndrome (PCOS) is most common endocrinologic disease in women of reproductive age with incidence of 6.6 ~ 8%.
- Trial name
- NCT03134482
- Testing
- IVM, Minimal stimulation IVF
- Where
- 2 sites in South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- CHA University
Infertility, Sterility
Real-world Evidence on Follitropin Delta Individual Dosing
As part of the in vitro fertilisation treatment, ovarian stimulation is routinely performed. For this purpose, FSH preparations are used.
- Trial name
- NCT05173597
- Testing
- Follitropin delta
- Where
- Germany
- Volunteers
- 850 people
- Sponsor
- University of Luebeck
Ovarian Hyperstimulation Syndrome, Pregnancy Related
Freeze All Strategy Versus Fresh Embryo Transfer After GnRH Analogue Trigger
Ovarian hyperstimulation syndrome (OHSS) is one of the most dangerous complications of assisted reproduction technology (ART), described in approximatively 3 to 10% of stimulation cycles although an underestimation of the real…
- Trial name
- NCT05362734
- Testing
- obstetric outcomes after fresh versus cryopreserved embryo transfer
- Volunteers
- 1,396 people
- Sponsor
- Istituto Clinico Humanitas
PCOS, OHSS
Use of Degarelix in Controlled Ovarian Hyperstimulation (COH) Protocol for Women With PoliCystic Ovarian Syndrome (PCOS)
In this study the effectiveness of degarelix, a long acting GnRH antagonist administered in a unique administration of 20 mg the first day of menstrual cycle, to prevent ovarian hyperstimulation syndrome (OHSS) in PCOS women at…
- Conditions
- PCOS, OHSS, INFERTILITY
- Trial name
- NCT01709942
- Testing
- degarelix (long acting GnRH antagonist), cetrorelix 0.25mg
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Ovarian Hyperstimulation Syndrome
Double GnRH Antagonist Daily Dose in Hyperresponding IVF/ICSI Cycles May Prevent the OHSS
The possibility to prevent the early ovarian hyperstimulation syndrome (OHSS) by doubling the daily dose of GnRH-antagonist in women stimulated with the antagonist protocol who are at risk for OHSS was evaluated.
- Trial name
- NCT01477970
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Iakentro Fertility Centre
Ovarian Hyperstimulation Syndrome
Ovarian Hyperstimulation Syndrome Using Calcium Infusion
the incidence of OHSS and clinical outcomes after calcium IV infusion in high-risk women undergoing ART
- Trial name
- NCT05198128
- Testing
- Calcium intravenous infsuion, 0.9 % saline
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Complications Associated With Artificial Fertilization, Disorder of Endocrine Ovary
Cabergoline and Hydroxyethyl Starch in Ovarian Hyperstimulation Syndrome Prevention
The purpose of this study is to assess whether, in GnRH agonist in vitro fertilization (IVF) cycles, where there is a risk of ovarian hyperstimulation syndrome (OHSS), the addition of cabergoline to the hydroxyethyl starch…
- Trial name
- NCT01530490
- Testing
- Cabergoline and Hydroxyethyl Starch, Hydroxyethyl Starch
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital de Cruces
Male Infertility, Female Infertility
'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists"
The purpose of this study is to compare two different strategies to implement the existing Guideline programme on Subfertility, as issued by the Dutch Society of Obstetrics and Gynaecology (NVOG).
- Conditions
- Male Infertility, Female Infertility, Ovarian Hyperstimulation Syndrome, Premature Ovarian Failure
- Trial name
- NCT00119925
- Testing
- patient education, professional audit and feedback (guideline adherence), professional education (communication/shared decision making)
- Where
- 16 sites in Netherlands
- Volunteers
- 5,200 people
- Sponsor
- Radboud University Medical Center