Clinical trials: Ovarian Reserve
Endometriosis
Ovarian Reserve Following Medical Therapy in Patients With Endometriosis
This study aims to investigate whether there is an effect on ovarian reserve from medical therapy for endometriosis. Although the therapeutic efficacy of medical hormone therapy on ovarian endometriosis has been proven in many…
- Trial name
- NCT06799754
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Crohn Disease, Ovary Disease
Ovarian Reserve in Crohn's Disease
Crohn's disease reduces fertility by inducing inflammation both directly and in the fallopian tubes and ovaries and indirectly through surgical interventions and tubal adhesions associated with disease treatment.
- Conditions
- Crohn Disease, Ovary Disease, Anti-Mullerian Hormone Deficiency
- Trial name
- NCT03897400
- Testing
- AMH levels in young women with crohn's disease will be considered.
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cancer, Toxicity Due to Chemotherapy
Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer
The purpose of this study is to determine the efficacy of a temporary ovarian suppression obtained by administration of a gonadotropin releasing hormone agonist during alkylating agents containing chemotherapy on ovarian reserve…
- Conditions
- Cancer, Toxicity Due to Chemotherapy, Sarcoma, Osteosarcoma
- Trial name
- PRESOV (NCT02856048)
- Testing
- Triptorelin (GnRHa) + Chemotherapy
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility, Decreased Ovarian Reserve
A Trial of Dehydroepiandrosterone (DHEA) Treatment for in Vitro Fertilization (IVF)
Our long term goal is to elucidate the role of DHEA on follicular dynamics in the human ovary and to better understand the interaction of DHEA supplementation with other treatments for ovulation induction, especially among older…
- Trial name
- NCT00419913
- Testing
- Dehydroepiandrosterone
- Where
- 2 sites in United States, Austria
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Infertility, Female
Caloric Intake and Ovarian Reserve
The goal of this study is to observe the impact of caloric intake on ovarian reserve as measured by anti-müllerian hormone (AMH) levels and antral follicles (AFC) visualized on ultrasound.
- Trial name
- NCT03604770
- Testing
- Survey & Food Diary
- Where
- United States
- Sponsor
- TriHealth Inc.
Endometriosis Related Infertility
Surgery Before Embryo Transfer in ERROR (Endometrioma Related Reduction in Ovarian Reserve)
This prospective study evaluates the pregnancy results after laparoscopic endometriosis operation in infertile patients with ERROR (endometrioma related reduction in ovarian reserve)
- Trial name
- NCT04233983
- Testing
- Laparoscopic Endometriosis Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uludag University
Anti-Mullerian Hormone Isoforms
Measurement of Different Anti-Müllerian Hormone Isoforms in Expected Poor Responders
This study wants to evaluate significant clinical impact of different AMH isoforms in serum can be present or absent in expected poor responder participants.
- Trial name
- NCT03826888
- Where
- United Arab Emirates
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Ovarian Reserve
Antioxidants vs. Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve
Two group of patients were selected. Group 1 represents 46 patients that received ovarian-biostimulation monthly for three months. Group 2 represents 32 patients that received antioxidant therapy daily for 3 months.
- Trial name
- NCT03621683
- Testing
- blood rich plasma platelets, Antioxidant therapy
- Where
- Venezuela
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Lucy Coleman
Infertility
Hormone-free Antral Retrieval for Viable Embryo Storage & Transfer
This study is testing whether eggs can be collected from small follicles without using the usual ovarian stimulation medications. Participants will have up to three egg retrieval procedures.
- Trial name
- HARVEST (NCT07801105)
- Testing
- CAPA-IVM System, Serial Unstimulated Transvaginal Oocyte Retrieval, ICSI, Blastocyst Culture, PGT-A, Embryo Vitrification/Accumulation, and Single Euploid Embryo Transfer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kevin Doody
Cystic Fibrosis, Infertility, Female
Ovarian Reserve in Women With Cystic Fibrosis and the Correlation With Demographic and Clinical Parameters
The main objective of this study is to assess the ovarian reserve of CF patients via measurement of AMH and AFC. Secondly, we aim to correlate between the ovarian reserve and demographic and clinical characteristics of these…
- Trial name
- NCT05029817
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Poor Ovarian Response
the Effect of Transcutaneous Electrical Acupoint Stimulation on the Quality of Oocyte on Poor Ovarian Response(POR)
Patients in experimental group will be given transcutaneous electrical acupoint stimulation (TEAS) treatment for 12 weeks prior to controlled ovarian stimulation (COS).The patients will be given three times acupuncture every week…
- Trial name
- POR (NCT03994614)
- Testing
- TEAS
- Where
- China
- Volunteers
- 92 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Ovarian Reserve, Endometrioma
Endometrioma Per se Versus Treatment Related Reduction in Ovarian Reserve (ERROR-2 Trial)
The present multi-center study aimed to evaluate whether endometrioma-associated decline in ovarian reserve is progressive in the absence of an intervention and is greater in magnitude than the natural decline over time.
- Trial name
- ERROR2 (NCT03620838)
- Testing
- oral contraceptive pill, oral progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Diminished Ovarian Reserve, IVF
Study of G-CSF for DOR in Patients Undergoing IVF
Diminished ovarian reserve (DOR) is defined by reduced follicle counts in women, associated with decreased fertility and lower success rates with In Vitro Fertilization (IVF).
- Conditions
- Diminished Ovarian Reserve, IVF, G-CSF, Granulocyte Colony Stimulating Factor
- Trial name
- NCT07871825
- Testing
- Neupogen 300 μg subcutaneous injection, Subcutaneous injections of a saline solution
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Center for Human Reproduction
Female Infertility
Effectiveness of Low Dose Gonadotropin Stimulation Protocol Vs High Dose Gonadotropin Protocol in Poor Responders
In the present study we examined the effect of addition of CC to a low dose gonadotropin (150 IU/day) / GnRH antagonist protocol in comparison to a high gonadotropin dose (300 IU/day) regiment (short protocol) in women with poor…
- Trial name
- NCT06778733
- Testing
- Clomiphane citrate, recombinant human Follicle-Stimulating Hormone (r-FSH-alfa)
- Where
- 2 sites in Greece
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Athens
Disorder of Phosphate, Calcium and Vitamin D Metabolism, Female Infertility Due to Diminished Ovarian Reserve
Vitamin D Influence on Oocyte Donation
Objective: To investigate the correlation between total and bioavailable serum 25-OH vitamin D, ovarian reserve and ovarian response to controlled stimulation in egg donors.
- Conditions
- Disorder of Phosphate, Calcium and Vitamin D Metabolism, Female Infertility Due to Diminished Ovarian Reserve, Hormonal Requirement, Reproductive Disorder
- Trial name
- NCT02341365
- Testing
- vitamin D,AMH, AFC, reproductive outcome egg recipients
- Volunteers
- 269 people
- Sponsor
- IVI Madrid
Female Infertility, Reproductive Health
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Female Fertility
This study evaluates the effects of a daily dietary supplement (WeNatal For Her) on markers of female fertility, reproductive health, and sexual health over three menstrual cycles.
- Conditions
- Female Infertility, Reproductive Health, Fertility, Hormonal Imbalance
- Trial name
- NCT07740187
- Testing
- WeNatal For Her Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Diminished Ovarian Reserve
A Clinical Study of Chinese Herbal Compound TJAOA101 in Therapy of Diminished Ovarian Reserve
Currently, no drugs have been developed for DOR. We developed the Chinese herbal compound TJAOA101 and has validated its effects in animals.
- Trial name
- NCT05459493
- Testing
- TJAOA101
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Ovary Injury
Effect of Laparoscopic Suturing Versus Bipolar Coagulation on Ovarian Reserve in Patients Undergoing Endometriotic Ovarian Cystectomy.
In women undergoing laparoscopic ovarian cystectomy which is less harmfull on the ovarian reserve (electrocoagulation or suturing).
- Trial name
- Eolsb (NCT03989856)
- Testing
- 2-0 polyglican absorbable sutures, Diathermy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypogonadism; Ovarian, Female Infertility
Effect of 12 Weeks of Acupuncture on AMH and COH in Low Responder Patients
the investigators want to study whether 12 weeks of acupuncture has any effect on AMH and the ovarian reserve in women with low ovarian reserve (low responders).
- Trial name
- NCT03080584
- Testing
- acupuncture
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Dansk Fertilitetsklinik
Assisted Reproductive Techniques
Dual Ovarian Stimulation (Duostim) and Shanghai Protocols in Poor Ovarian Responders
A combination of follicular phase stimulation and luteal phase stimulation in the same cycle, can be a valuable choice in poor responder patients with reduced ovarian reserve, in order to achieve extreme the number of oocytes in…
- Trial name
- NCT06199960
- Testing
- Doustim protocol
- Where
- Iran
- Volunteers
- 116 people
- Sponsor
- Royan Institute