Clinical trials: Ovarian Resistance Syndrome
Polycystic Ovary Syndrome
Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction
Polycystic Ovary Syndrome (PCOS) is characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovaries. Insulin resistance (IR) is a common feature of PCOS, and the resultant hyperinsulinemia is theorized to promote…
- Trial name
- TIN-PCOS-AOD (NCT03229408)
- Testing
- Salsalate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Anxiety, Fatigue
Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
This clinical trial studies the quality of life and care needs of patients with persistent or recurrent ovarian cancer, fallopian tube cancer, or peritoneal cancer.
- Conditions
- Anxiety, Fatigue, Nausea and Vomiting, Neurotoxicity Syndrome
- Trial name
- NCT01372787
- Testing
- Assessment of Therapy Complications, Medical Chart Review, Quality-of-Life Assessment
- Where
- 144 sites in United States
- Volunteers
- 103 people
- Sponsor
- Gynecologic Oncology Group
Polycystic Ovary Syndrome
Plant Exosomes and Patients Diagnosed With Polycystic Ovary Syndrome (PCOS) 17
The purpose of this study is to see if substances contained in ginger or aloe plants, called exosomes, will treat and improve the condition polycystic ovary syndrome
- Trial name
- NCT03493984
- Testing
- Ginger exosomes, Aloe exosomes
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Polycystic Ovary Syndrome, Insulin Resistance
MicroRNA as Biomarkers for Development of Metabolic Syndrome in Women With Polycystic Ovary Syndrome
The aim of this study is to explore the microRNA profile in serum of women with Polycystic Ovary Syndrome and investigate the correlation between the microRNA profile and markers of metabolic syndrome.
- Trial name
- NCT03142633
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Holbaek Sygehus
Polycystic Ovary Syndrome
Could the Therapy With Inositol Affect the Cardiovascular Risk in PCOS Women? Results of a Randomized Clinical Trial
Polycystic ovary syndrome (PCOS) is associated with an increased cardiovascular risk. The aim of the study was to evaluate long-term effects of inositol on some cardiovascular risk factors in PCOS patients.
- Trial name
- NCT01574261
- Testing
- Inositol
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
PCOS, Myo-inositol-resistance
Myo-inositol Plus Alpha-lactalbumin in PCOS Myo-inositol-resistant Patients
The investigator's aim is to evaluate if the combination of myo-inositol and alpha-lactalbumin can overcome the resistance to myo-inositol in PCOS patients
- Trial name
- NCT03667443
- Testing
- Myo-inositol + folic a. + α-lactalbumin, Myo-inositol + folic a.
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Lo.Li.Pharma s.r.l
Polycystic Ovary Syndrome, Insulin Resistance
The Role of Insulin Resistance in PCOS
Polycystic ovary syndrome (PCOS) phenotype can be structured into three components: anovulation, hyperandrogenism and the metabolic syndrome (of which hyperinsulinemia, secondary to insulin resistance, is the central…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Obesity
- Trial name
- NCT00173043
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Polycystic Ovary Syndrome
Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome
Objective of the study was to evaluate the effect of combination of oral Coenzyme Q10 (CoQ10), with clomiphene citrate (CC) for ovulation induction in CC-resistant polycystic ovary syndrome (PCOS).In a prospective controlled…
- Trial name
- NCT01910766
- Testing
- Coenzyme Q10, clomiphene citrate
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome, Familial Partial Lipodystrophy
Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)
Diagnostic case-control study (1 case for 2 controls). Inclusion of patients with severe insulin resistance syndrome of genetic origin, then inclusion of controls: patients examined for PCOS in day hospital with matching age (+/…
- Conditions
- Polycystic Ovary Syndrome, Familial Partial Lipodystrophy, LMNA (LaMin Nuclear A) Related Disorders
- Trial name
- ANDROLIPO (NCT07412028)
- Testing
- Genetic analysis, Biological analysis, imaging test
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polycystic Ovary Syndrome
SGLT2 Inhibitors in Patients With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often…
- Trial name
- PCOS (NCT04700839)
- Testing
- SGLT2 inhibitors, Metformin
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Shanghai 10th People's Hospital
Clomiphene Citrate Resistant Polycystic Ovary Syndrome
Efficacy of Vit E in PCOS Resistant to Clomiphene Citrate
This study evaluate the addition of Vit E to clomiphene citrate in the treatment of poly cystic ovary.Half the patients will receive both Vit E and clomiphene citrate the other half will receive clomiphene citrate only.
- Trial name
- NCT03674385
- Testing
- vitamin E, Metformin, Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Obesity
Females, Aging, Metabolism, and Exercise
This study is designed to determine whether a reduction in hormones (such as occurs during menopause) causes a decrease in calories burned during physical activity.
- Trial name
- FAME (NCT01712230)
- Testing
- GnRH agonist, Supervised cardiovascular exercise
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Insulin Resistance, Oxidative Stress
Alpha Lipoic Acid and Polycystic Ovary Syndrome
The study will recruit 40 subjects with Polycystic Ovary Syndrome (PCOS) as defined by the NIH criteria. The subjects will be pre-screened for insulin sensitivity using fasting insulin and glucose levels and oral glucose…
- Trial name
- NCT00505427
- Testing
- Alpha Lipoic Acid
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Polycystic Ovary Syndrome, Insulin Resistance
Comparison of Alogliptin Versus Alogliptin and Pioglitazone on Insulin Resistance of Metformin Treated Women With PCOS
The purpose of this study was to determine whether dual treatment with metformin and alogliptin is more effective than treatment with metformin, alogliptin and pioglitazone in the treatment of obese women with polycystic ovary…
- Trial name
- NCT02683226
- Testing
- Vipdomet, Incresync
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
PCOS
A Metabolomic Study of Polycystic Ovary Syndrome With Insulin Resistance and Its Relationship With TCM Syndrome Types
The type-2 diabetes mellitus（T2DM）, metabolic syndrome, cardiovascular disease complications induced by polycystic ovary syndrome(PCOS) with insulin resistance(IR）, which become serious threat to public health.
- Trial name
- NCT02992093
- Testing
- all the indicators
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
Acute Myeloid Leukemia, Brain Glioblastoma
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer
This randomized pilot clinical trial studies health care coach support in reducing acute care use and cost in patients with cancer.
- Conditions
- Acute Myeloid Leukemia, Brain Glioblastoma, Estrogen Receptor Negative, Extensive Stage Small Cell Lung Carcinoma
- Trial name
- NCT03154190
- Testing
- Best Practice, Laboratory Biomarker Analysis, Supportive Care
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Stanford University
Polycystic Ovary Syndrome
Evaluation of Oral Lipid Ingestion in Relation to Ovarian Androgen Secretion in Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine the relationship between lipid-induced inflammation and ovarian androgen secretion in women with polycystic ovary syndrome (PCOS); and to examine the effect of salsalate and polygonum…
- Trial name
- ELI-ROAS (NCT01489319)
- Testing
- Salsalate
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Indiana University
Polycystic Ovarian Syndrome, Insulin Sensitivity
PED/PEA-15 Protein, PCOS, Obesity, Insulin Sensitivity Indexes, Metformin, Oral Contraceptives
Insulin-resistance plays an important role in polycystic ovary syndrome (PCOS) physiopathology. The phosphoprotein enriched in the diabetes (PED/PEA-15), a 15 kDa protein related to insulin sensitivity, is over-expressed in type…
- Trial name
- NCT00948402
- Testing
- Metformin, oral contraceptive
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federico II University
Polycystic Ovary Syndrome
Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study
The purpose is to investigate the effects of 2 different treatments (drospirenone/ethinyl estradiol versus rosiglitazone) on insulin sensitivity and androgen levels, inflammatory markers, vascular markers and bone development in…
- Trial name
- NCT00640224
- Testing
- rosiglitazone, drospirenone/ethinyl estradiol
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Silva Arslanian
Study the Relationship Between Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome
Correlation of Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome
We designed a study to determine if ovarian volume (OV) and/or follicle number (FN) are independently associated with abnormal metabolic findings in women diagnosed with PCOS.
- Trial name
- NCT05661565
- Testing
- No intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University