Clinical trials: Ovarian Resistance Syndrome
Polycystic Ovary Syndrome, Insulin Resistance
The Effect of Acupuncture on Insulin Sensitivity Polycystic Ovary Syndrome
Hyperinsulinemia and insulin resistance play a key role in the pathogenesis of polycystic ovary syndrome (PCOS). Insulin resistance is significantly associated with the long-term risks of metabolic syndrome and cardiovascular…
- Trial name
- NCT02026323
- Testing
- acupuncture
- Where
- China
- Volunteers
- 112 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Infertility
Comparison Between Letrozole and Urinary Purified FSH in Women With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome.
210 women with clomiphene resistant PCOS will be randomly divided into 3 equal groups using computer generated random numbers. Group 1 will receive FSH, group 2 will have Letrozole and group 3 will act as the control group with…
- Trial name
- FSH (NCT02304107)
- Testing
- FSH, Letrozole
- Where
- 2 sites in Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Insulin Resistant PCOS
Magnesium Oxide and Letrozole Versus Letrozole Alone on Ovarian Response in Insulin Resistant PCOS
Does pretreatment with magnesium oxide followed by letrozole increase ovulation rate? What medical problems do participants have when taking drug magnesium oxide and letrozole? Researchers will compare magnesium oxide and…
- Trial name
- NCT07766590
- Testing
- Experimental drug: Magnesium oxide (365 mg), Letrozole 2.5mg
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Polycystic Ovary Syndrome
SGLT2 Inhibitors in Patients With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often…
- Trial name
- PCOS (NCT04700839)
- Testing
- SGLT2 inhibitors, Metformin
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Shanghai 10th People's Hospital
PCOS, Insulin Resistance
Myoinositol Treatment and Asprosin Levels in PCOS
Policystic ovary syndrome is the most common endocrinopthy during reproductive period. One of the factors implicated in the pathogenesis is insulin resistance.
- Trial name
- NCT05951309
- Testing
- inofolic combi, Glucophage 500Mg Tablet
- Where
- Cyprus
- Volunteers
- 30 people
- Sponsor
- Near East University, Turkey
Polycystic Ovarian Syndrome (PCOS), Infertility
Effect of NAE on Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovarian Syndrome (PCOS) is a multifaceted endocrine metabolic condition impacting about 5-10% of women throughout their reproductive lifespan.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Infertility, Metabolic Disorders
- Trial name
- NAE-PCOS (NCT07603505)
- Testing
- Herbal Formulation, Metformin XR, Metformin 750 mg and herbal formulation 500 mg
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Jinnah Sindh Medical University
Metabolic Syndrome, Polycystic Ovary Syndrome
Evaluation of Licorice Root on Metabolic Syndrome in Polycystic Ovary Syndrome Females
The goal of this study is to learn about the effect of licorice root powder on parameters of metabolic syndrome in those women diagnosed with PCOS with age range of 15-49 years of age.
- Trial name
- NCT06043375
- Testing
- Licorice Root Powder Capsule
- Where
- Pakistan
- Volunteers
- 55 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Polycystic Ovary, Obesity
Polycystic Ovary Syndrome and BETATROPHIN
This is an original study giving an information about the association body mass index, polycystic ovary syndrome and betatrophin.
- Trial name
- NCT04448730
- Testing
- serum marker levels
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Hatice Akkaya
Infertility, Polycystic Ovarian Syndrome
IVF Versus Gonadotropin Therapy in Women With CC Resistant PCOS
The purpose of this study is to compare the efficacy of in vitro fertilization (IVF) versus gonadotropin therapy in infertile women having clomiphene citrate (CC) resistant polycystic ovarian syndrome (PCOS).
- Trial name
- NCT02458963
- Testing
- IVF, Gonadotropin
- Where
- 2 sites in Egypt
- Sponsor
- Mohamed Sayed Abdelhafez
Laparoscopic, Ovarian Drilling
Unilateral vs Bilateral Laparoscopic Ovarian Drilling In Clomiphene Citrate Resistant Cases of Polycystic Ovarian Syndrome
The aim of the current study is to compare the efficacy of laparoscopic unilateral ovarian drilling with bilateral ovarian drilling in clomiphene citrate resistant cases of polycystic ovarian syndrome in terms of clinical…
- Conditions
- Laparoscopic, Ovarian Drilling, Clomiphene Citrate, Polycystic Ovarian Syndrome
- Trial name
- NCT06537102
- Testing
- Unilateral laparoscopic ovarian drilling, Bilateral laparoscopic ovarian drilling
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Tanta University
Polycystic Ovary Syndrome (PCOS) Women, Polycystic Ovary Syndrome
Extended Letrozole Protocol Versus Letrozole Plus Inositol for Induction of Ovulation in Letrozole Resistant PCOS Women
Extended letrozole protocol versus letrozole plus Inositol for Induction of ovulation in letrozole resistant PCOS Women
- Trial name
- NCT07635082
- Testing
- ELP (Extended Letrozole Protocol), LIP (Letrozole + Inositol Protocol)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Eman Basuni Ebrahim Mowad
Polycystic Ovary Syndrome
Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine if insulin resistance (how well the body uses insulin and clears sugar) can affect cortisol levels in normal healthy women and women with polycystic ovary syndrome of all body weights.
- Trial name
- NCT00694759
- Testing
- pioglitazone, metformin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Insulin Resistance, Oxidative Stress
Alpha Lipoic Acid and Polycystic Ovary Syndrome
The study will recruit 40 subjects with Polycystic Ovary Syndrome (PCOS) as defined by the NIH criteria. The subjects will be pre-screened for insulin sensitivity using fasting insulin and glucose levels and oral glucose…
- Trial name
- NCT00505427
- Testing
- Alpha Lipoic Acid
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Polycystic Ovary Syndrome
Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS
Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women of reproductive age and despite decades of research the etiology the disorder is not known.
- Trial name
- PULSE (NCT01482286)
- Testing
- Metformin, Dietary Restriction, Exercise Training
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Pennington Biomedical Research Center
Polycystic Ovary Syndrome, Abnormal Weight Gain
Go Girls! Fitness Support Group Intervention Effectiveness Study
The main purpose of this study is to determine if the Go Girls! program to take place at the Kluge Children's Rehabilitation Center Therapeutic Recreation Gymnasium, intended to introduce girls to a fun, non-threatening…
- Conditions
- Polycystic Ovary Syndrome, Abnormal Weight Gain, Excess Weight, Insulin Resistance
- Trial name
- CBS002 (NCT02117063)
- Testing
- Go Girls! Fitness Support Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome, Insulin Resistance
Endocrine and Menstrual Disturbances in Women With Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive age women, which causes disordered follicle growth and ovulation resulting in infertility.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Vitamin D Deficiency, Obesity
- Trial name
- EMDPCOS (NCT03652987)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- St George's, University of London
Polycystic Ovary Syndrome
Effect of Laser Acupuncture on Insulin Resistance in Obese Women With Polycystic Ovarian Syndrome
This study will be conducted to investigate the effect of laser acupuncture on insulin resistance in obese women with polycystic ovarian syndrome.
- Trial name
- NCT06549647
- Testing
- low caloric diet, Laser Acupuncture
- Volunteers
- 40 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome, Resistance, Insulin
Effects of Myo-inositol in Women With Polycystic Ovary Syndrome
The study will be carried out at the hospital of the medical school of sao paulo (HC-FMUSP) and the goal is to compare the effects of the administration of myo-inositol in relation to the effects of metformin in women with…
- Conditions
- Polycystic Ovary Syndrome, Resistance, Insulin, Glucose Intolerance
- Trial name
- NCT04892186
- Testing
- Myo-inositol, Metformin
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
PCOS (Polycystic Ovary Syndrome)
Comparative Effect of Myo-inositol With That of D-chiro-inositol on Insulin Resistance in Infertile Women With Polycystic Ovary Syndrome (PCOS).
This randomized controlled trial was conducted in the Department of Reproductive Endocrinology and Infertility, BSMMU.A total of 80 infertile women ofPCOS withinsulinresistanceparticipatedinthestudyandwere randomly allocated into…
- Trial name
- PCOS HOMA IR (NCT07453680)
- Testing
- Tab Myo-inositol 750mg, D-chiro-inositol 500mg
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- Mst.Sumyara Khatun
PCOS, Insulin Resistance
Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. Hyperandrogenism is the central feature of PCOS.
- Trial name
- NCT02766803
- Testing
- Simvastatin and micronized trans-resveratrol
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences